GR3002483T3 - Bridged bicyclic imides as anxiolytics and antidepressants - Google Patents

Bridged bicyclic imides as anxiolytics and antidepressants

Info

Publication number
GR3002483T3
GR3002483T3 GR91401123T GR910401123T GR3002483T3 GR 3002483 T3 GR3002483 T3 GR 3002483T3 GR 91401123 T GR91401123 T GR 91401123T GR 910401123 T GR910401123 T GR 910401123T GR 3002483 T3 GR3002483 T3 GR 3002483T3
Authority
GR
Greece
Prior art keywords
bridged bicyclic
anxiolytics
antidepressants
bicyclic imides
imides
Prior art date
Application number
GR91401123T
Other languages
English (en)
Inventor
Gene Michael Bright
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of GR3002483T3 publication Critical patent/GR3002483T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GR91401123T 1986-10-21 1991-08-16 Bridged bicyclic imides as anxiolytics and antidepressants GR3002483T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1986/002224 WO1988003024A1 (en) 1986-10-21 1986-10-21 Bridged bicyclic imides as anxiolytics and antidepressants

Publications (1)

Publication Number Publication Date
GR3002483T3 true GR3002483T3 (en) 1992-12-30

Family

ID=22195680

Family Applications (1)

Application Number Title Priority Date Filing Date
GR91401123T GR3002483T3 (en) 1986-10-21 1991-08-16 Bridged bicyclic imides as anxiolytics and antidepressants

Country Status (26)

Country Link
EP (1) EP0268369B1 (el)
JP (1) JPS63112581A (el)
KR (1) KR900000565B1 (el)
CN (1) CN1015987B (el)
AT (1) ATE66222T1 (el)
AU (1) AU579963B2 (el)
DD (1) DD263531A5 (el)
DE (1) DE3772158D1 (el)
DK (1) DK547487A (el)
EG (1) EG18718A (el)
ES (1) ES2031517T3 (el)
FI (1) FI90775C (el)
GR (1) GR3002483T3 (el)
HU (1) HU198203B (el)
IE (1) IE60378B1 (el)
IL (1) IL84206A (el)
MX (1) MX8898A (el)
MY (1) MY101833A (el)
NO (1) NO882715L (el)
NZ (1) NZ222229A (el)
PH (1) PH23806A (el)
PL (1) PL149172B1 (el)
PT (1) PT85944B (el)
WO (1) WO1988003024A1 (el)
YU (1) YU45461B (el)
ZA (1) ZA877863B (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4748240A (en) * 1987-04-03 1988-05-31 American Home Products Corporation Psychotropic bicyclic imides
US4810789A (en) * 1987-08-28 1989-03-07 Bristol-Myers Company Process for buspirone hydrochloride polymorphic crystalline form conversion
WO1990002552A1 (en) * 1988-09-16 1990-03-22 Pfizer Inc. Antipsychotic 4-[4-(3-benzisothiazolyl)-1-piperazinyl]butyl bridged bicyclic imides
SU1825501A3 (ru) * 1990-10-29 1995-12-10 И.В. Комиссаров Dl-3-[(4-[4- (2-пиридил)-1- пиперазинил]бутил)] -1,8,8-триметил -3-азабицикло[3,2,1] октан-2,4-диона дигидрохлорид, проявляющий противотревожную, нейролептическую и противорвотную активность
CN101906107B (zh) * 2010-08-02 2012-12-26 南京林业大学 一种由α-蒎烯合成樟脑酸酐的方法
EP3610890A1 (en) 2012-11-14 2020-02-19 The Johns Hopkins University Methods and compositions for treating schizophrenia

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4006233A (en) * 1974-10-04 1977-02-01 Merck & Co., Inc. N-(pyrimidinyl)-tricyclo[3(or 4).2.2.02,4(or 5) ]-non (or dec)ene-dicarboximides
US4173646A (en) * 1974-10-04 1979-11-06 Merck & Co., Inc. Tricyclicdicarboximides
US4182763A (en) * 1978-05-22 1980-01-08 Mead Johnson & Company Buspirone anti-anxiety method
US4524206A (en) * 1983-09-12 1985-06-18 Mead Johnson & Company 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
US4562255A (en) * 1984-03-30 1985-12-31 American Home Products Corporation Substituted bi-alicyclic imides
JPS61238784A (ja) * 1985-04-17 1986-10-24 Sumitomo Seiyaku Kk コハク酸イミド誘導体及びその酸付加塩
DE3529872A1 (de) * 1985-08-21 1987-02-26 Kali Chemie Pharma Gmbh Neue tetraoxoverbindungen

Also Published As

Publication number Publication date
MX8898A (es) 1993-10-01
YU192087A (en) 1988-10-31
DK547487D0 (da) 1987-10-20
HU198203B (en) 1989-08-28
FI90775C (fi) 1994-03-25
ES2031517T3 (es) 1992-12-16
FI882942A (fi) 1988-06-20
IL84206A (en) 1992-07-15
DD263531A5 (de) 1989-01-04
AU579963B2 (en) 1988-12-15
CN87107107A (zh) 1988-05-04
MY101833A (en) 1992-01-31
EP0268369A1 (en) 1988-05-25
JPS63112581A (ja) 1988-05-17
PL268296A1 (en) 1988-08-18
EP0268369B1 (en) 1991-08-14
WO1988003024A1 (en) 1988-05-05
HUT47270A (en) 1989-02-28
PH23806A (en) 1989-11-23
JPH0448792B2 (el) 1992-08-07
NO882715D0 (no) 1988-06-20
ZA877863B (en) 1989-06-28
ATE66222T1 (de) 1991-08-15
PL149172B1 (en) 1990-01-31
AU7994687A (en) 1988-04-28
DE3772158D1 (de) 1991-09-19
IL84206A0 (en) 1988-03-31
FI882942A0 (fi) 1988-06-20
FI90775B (fi) 1993-12-15
IE872835L (en) 1988-04-21
PT85944A (en) 1987-11-01
NO882715L (no) 1988-06-20
PT85944B (pt) 1990-07-31
KR900000565B1 (ko) 1990-01-31
NZ222229A (en) 1989-12-21
YU45461B (en) 1992-05-28
EG18718A (en) 1993-12-30
KR880005120A (ko) 1988-06-28
IE60378B1 (en) 1994-07-13
CN1015987B (zh) 1992-03-25
DK547487A (da) 1988-04-22

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