DD263290A5 - Verfahren zur herstellung von neuen chinolinderivaten - Google Patents

Verfahren zur herstellung von neuen chinolinderivaten Download PDF

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Publication number
DD263290A5
DD263290A5 DD87302040A DD30204087A DD263290A5 DD 263290 A5 DD263290 A5 DD 263290A5 DD 87302040 A DD87302040 A DD 87302040A DD 30204087 A DD30204087 A DD 30204087A DD 263290 A5 DD263290 A5 DD 263290A5
Authority
DD
German Democratic Republic
Prior art keywords
lower alkyl
group
amino
hydrogen atom
dihydro
Prior art date
Application number
DD87302040A
Other languages
German (de)
English (en)
Inventor
Jun-Ichi Matsumoto
Teruyuki Miyamoto
Hiroshi Egawa
Shinichi Nakamura
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �������@�������������@��Kk���Kk�� filed Critical �������@�������������@��Kk���Kk��
Publication of DD263290A5 publication Critical patent/DD263290A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DD87302040A 1986-04-25 1987-04-22 Verfahren zur herstellung von neuen chinolinderivaten DD263290A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9754386 1986-04-25

Publications (1)

Publication Number Publication Date
DD263290A5 true DD263290A5 (de) 1988-12-28

Family

ID=14195155

Family Applications (1)

Application Number Title Priority Date Filing Date
DD87302040A DD263290A5 (de) 1986-04-25 1987-04-22 Verfahren zur herstellung von neuen chinolinderivaten

Country Status (17)

Country Link
US (1) US4886810A (no)
EP (1) EP0242789A3 (no)
JP (1) JP2572591B2 (no)
KR (1) KR870010005A (no)
CN (1) CN87103138A (no)
AU (1) AU7190987A (no)
DD (1) DD263290A5 (no)
DK (1) DK208787A (no)
FI (1) FI871788A (no)
HU (1) HU198198B (no)
IL (1) IL82246A0 (no)
NO (1) NO871727L (no)
PH (1) PH23326A (no)
PT (1) PT84749B (no)
SU (3) SU1582986A3 (no)
YU (4) YU73987A (no)
ZA (1) ZA872874B (no)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822801A (en) * 1984-07-20 1989-04-18 Warner-Lambert Company 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents
ATE75740T1 (de) * 1985-06-26 1992-05-15 Daiichi Seiyaku Co Pyridoncarbonsaeurederivate.
AU594983B2 (en) * 1985-10-29 1990-03-22 Dainippon Pharmaceutical Co. Ltd. Novel quinoline derivatives and processes for preparation thereof
DE3711193A1 (de) * 1987-04-02 1988-10-13 Bayer Ag 5-substituierte chinolon- und naphthyridoncarbonsaeure-derivate
US5563138A (en) * 1987-04-16 1996-10-08 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
IL88003A (en) * 1987-10-16 1992-11-15 Dainippon Pharmaceutical Co Quinoline derivatives,their preparation and pharmaceutical compositions containing them
EP0319906A3 (en) * 1987-12-11 1990-05-02 Dainippon Pharmaceutical Co., Ltd. Novel quinoline derivatives, processes for preparation thereof and antibacterial agent containing them
US4920120A (en) * 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
US5585491A (en) * 1988-01-25 1996-12-17 Otsuka Pharmaceutical Co., Ltd. Antibacterial agents
US5173484A (en) * 1988-02-05 1992-12-22 Bayer Aktiengesellschaft Quinolone- and naphthyridone carboxylic acid derivatives, process for their production, antibacterial compositions and feed additives containing them
DE3814517A1 (de) * 1988-02-05 1989-08-17 Bayer Ag Chinolon- und naphthyridoncarbonsaeurederivate, verfahren zu ihrer herstellung und sie enthaltende antibakterielle mittel und futterzusatzstoffe
AU609974B2 (en) * 1988-05-18 1991-05-09 Warner-Lambert Company Improved process for the preparation of 5-amino-7- (substituted amino)-quinoline-3-carboxylic acids
JPH0674261B2 (ja) * 1988-06-21 1994-09-21 塩野義製薬株式会社 キノロンカルボン酸誘導体
US5057523A (en) * 1988-09-22 1991-10-15 Abbott Laboratories Dipeptide quinolone derivatives
CA1332605C (en) * 1988-10-03 1994-10-18 Yasuhiro Nishitani Pyridonecarboxylic acids
US5262417A (en) * 1988-12-06 1993-11-16 The Upjohn Company Antibacterial quinolone compounds
US5324735A (en) * 1989-07-21 1994-06-28 Ss Pharmaceutical Co., Ltd. Quinoline carboxylic acid derivatives
ES2019551A6 (es) * 1990-04-11 1991-06-16 Ercros Sa Procedimiento para la obtencion de derivados del acido 6-fluor-1, 4-dihidro-4-oxo-7-piperacinil-3-quinlincarboxilico.
AU640481B2 (en) 1990-04-18 1993-08-26 Norwich Eaton Pharmaceuticals, Inc. Penicillan or cephalosporin derivatives of quinolonyl
DE4019023A1 (de) * 1990-06-14 1991-12-19 Bayer Ag Verfahren zur herstellung von chinolincarbonsaeuren
US5221676A (en) * 1992-02-06 1993-06-22 Warner-Lambert Company 7-substituted quinolones and naphthyridones as antibacterial agents
EP0677522A4 (en) * 1992-12-28 1995-12-27 Yoshitomi Pharmaceutical 8-METHOXYQUINOLONECARBOXYLIC ACID DERIVATIVE.
CA2152828A1 (en) * 1993-03-16 1994-07-07 Shin-Ichi Uesato 8-methoxy-quinolonecarboxylic acid derivatives
TW252107B (no) * 1993-08-27 1995-07-21 Hokuriku Pharmacetical Co Ltd
CA2175351A1 (en) * 1993-10-28 1995-05-04 Jun Nakano Quinolinecarboxylic acid derivative and salt thereof
MX9700872A (es) * 1994-08-02 1997-05-31 Procter & Gamble Procedimiento para producir antimicrobianos de quinolonil-lactama y compuestos intermediarios novedosos.
NZ290721A (en) * 1994-08-02 1999-03-29 Procter & Gamble Process for making quinolone-containing antimicrobial compounds
CA2210007A1 (en) * 1995-01-24 1996-08-01 Yasuo Ito Quinoline carboxylic acid
CN1268132A (zh) * 1997-06-24 2000-09-27 第一制药株式会社 顺式-取代的氟甲基吡咯烷衍生物
EP1666477B1 (en) 2003-09-10 2013-07-03 Kyorin Pharmaceutical Co., Ltd. 7-(4-substituted 3- cyclopropylaminomethyl-1- pyrrolidinyl) q uinolonecarboxylic acid derivative
GB0505969D0 (en) * 2005-03-23 2005-04-27 Novartis Ag Organic compounds
US7563805B2 (en) * 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
JP5063032B2 (ja) * 2005-05-19 2012-10-31 第一三共株式会社 トリ−、テトラ−置換−3−アミノピロリジン誘導体
EP2540715A1 (en) 2007-01-05 2013-01-02 Daiichi Sankyo Company, Limited Fused substituted aminopyrrolidine derivative
WO2008143343A1 (ja) * 2007-05-24 2008-11-27 Kyorin Pharmaceutical Co., Ltd. 14位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
DE3318145A1 (de) * 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
ZA852369B (en) * 1984-04-26 1985-12-24 Abbott Lab Quinoline antibacterial compounds
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
US4771054A (en) * 1985-01-23 1988-09-13 Warner-Lambert Company Antibacterial agents
US4657913A (en) * 1985-04-18 1987-04-14 Warner-Lambert Company Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents
AU594983B2 (en) * 1985-10-29 1990-03-22 Dainippon Pharmaceutical Co. Ltd. Novel quinoline derivatives and processes for preparation thereof
US4977154A (en) * 1985-12-12 1990-12-11 Warner-Lambert Company 5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents
US4668680A (en) * 1985-12-12 1987-05-26 Warner-Lambert Company 5-amino-6,8-difluoroquinolones as antibacterial agents
US4771055A (en) * 1986-07-28 1988-09-13 Warner-Lambert Company 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acids

Also Published As

Publication number Publication date
FI871788A0 (fi) 1987-04-23
JPS6345261A (ja) 1988-02-26
ZA872874B (en) 1987-10-12
EP0242789A2 (en) 1987-10-28
EP0242789A3 (en) 1990-09-05
PT84749A (en) 1987-05-01
SU1582986A3 (ru) 1990-07-30
HUT45520A (en) 1988-07-28
YU73987A (en) 1988-08-31
DK208787A (da) 1987-10-26
CN87103138A (zh) 1987-11-04
FI871788A (fi) 1987-10-26
YU27688A (en) 1988-12-31
SU1588282A3 (ru) 1990-08-23
AU7190987A (en) 1987-10-29
NO871727L (no) 1987-10-26
DK208787D0 (da) 1987-04-24
HU198198B (en) 1989-08-28
NO871727D0 (no) 1987-04-24
IL82246A0 (en) 1987-10-30
YU27788A (en) 1990-04-30
SU1588281A3 (ru) 1990-08-23
PH23326A (en) 1989-07-14
YU27488A (en) 1988-10-31
US4886810A (en) 1989-12-12
PT84749B (en) 1989-06-07
KR870010005A (ko) 1987-11-30
JP2572591B2 (ja) 1997-01-16

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Legal Events

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ENJ Ceased due to non-payment of renewal fee