DD235872A5 - Verfahren zur herstellung von benzo-(pyrano und thiopyrano)-pyridine - Google Patents

Verfahren zur herstellung von benzo-(pyrano und thiopyrano)-pyridine Download PDF

Info

Publication number
DD235872A5
DD235872A5 DD85276081A DD27608185A DD235872A5 DD 235872 A5 DD235872 A5 DD 235872A5 DD 85276081 A DD85276081 A DD 85276081A DD 27608185 A DD27608185 A DD 27608185A DD 235872 A5 DD235872 A5 DD 235872A5
Authority
DD
German Democratic Republic
Prior art keywords
alkyl
hydroxy
formula
ring
compounds
Prior art date
Application number
DD85276081A
Other languages
German (de)
English (en)
Inventor
Alan J Hutchison
Original Assignee
����`��@���k��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ����`��@���k�� filed Critical ����`��@���k��
Publication of DD235872A5 publication Critical patent/DD235872A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
DD85276081A 1984-05-10 1985-05-07 Verfahren zur herstellung von benzo-(pyrano und thiopyrano)-pyridine DD235872A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60903784A 1984-05-10 1984-05-10

Publications (1)

Publication Number Publication Date
DD235872A5 true DD235872A5 (de) 1986-05-21

Family

ID=24439108

Family Applications (1)

Application Number Title Priority Date Filing Date
DD85276081A DD235872A5 (de) 1984-05-10 1985-05-07 Verfahren zur herstellung von benzo-(pyrano und thiopyrano)-pyridine

Country Status (20)

Country Link
US (1) US4604397A (da)
EP (1) EP0161218B1 (da)
JP (1) JPS60243090A (da)
AR (1) AR243526A1 (da)
AT (1) ATE64735T1 (da)
AU (1) AU592308B2 (da)
CA (1) CA1298582C (da)
DD (1) DD235872A5 (da)
DE (1) DE3583307D1 (da)
DK (1) DK168571B1 (da)
ES (5) ES8706687A1 (da)
FI (1) FI83652C (da)
GR (1) GR851116B (da)
HU (1) HU199476B (da)
IE (1) IE57978B1 (da)
IL (1) IL75135A (da)
NO (1) NO162860C (da)
NZ (1) NZ212031A (da)
PT (1) PT80415B (da)
ZA (1) ZA853507B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8426584D0 (en) * 1984-10-19 1984-11-28 Beecham Group Plc Compounds
US4666916A (en) * 1985-11-08 1987-05-19 Ciba-Geigy Corporation Hexahydro-(1)-benzo-(pyrano and thiopyrano) (4,3-C)pyridines, useful as serotin-2 blocking agents
US4792548A (en) * 1986-05-21 1988-12-20 Warner-Lambert Company Trans-benzopyran-(4,3-b)-1,4-oxazine derivatives, intermediates and pharmaceutical use
US4801605A (en) * 1986-08-29 1989-01-31 Ciba-Geigy Corporation 3-amino-dihydro-[1]-benzopyrans and benzothiopyrans
FR2619112B1 (fr) * 1987-08-07 1989-11-17 Synthelabo Derives de (piperidinyl-4)methyl-2 benzo(b)furo(2,3-c) pyridines, leur preparation et leur application en therapeutique
US4992465A (en) * 1988-09-27 1991-02-12 Ciba-Geigy Corporation 3-amino-dihydro-(1)-benzopyrans
US5962463A (en) * 1992-10-09 1999-10-05 Massachusetts Institute Of Technology Methods of stimulating non-amyloidogenic processing of the amyloid precursor protein
FR2721027B1 (fr) * 1994-06-08 1996-07-19 Adir Nouveaux dérivés tétracycliques de la 1,4-oxazine, leur procédé de préparation et les compositions pharmaceutiques les contenant.
FR2741074B1 (fr) 1995-11-09 1997-12-19 Adir Nouveaux composes tetracycliques de la 1,4-oxazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6342533B1 (en) 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
PL350924A1 (en) * 1999-04-06 2003-02-10 Sepracor Inc Derivatives of venlafaxine and methods of preparing and using the same
WO2005032485A2 (en) * 2003-10-03 2005-04-14 Psychogenics, Inc. Compounds and methods for the treatment of attention-deficit hyperactivity disorder
WO2007005961A2 (en) * 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and o-desmethylvenlafaxine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
BRPI1003506B1 (pt) 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143819A (da) * 1965-09-27
US3514464A (en) * 1967-05-29 1970-05-26 Little Inc A 5-oxo-1,2,3,4-tetrahydro-5h-(1)benzopyrano(3,4-c)pyridines
US3689497A (en) * 1971-03-09 1972-09-05 Warner Lambert Co Substituted benzopyrano (3,4-b) pyridines and process for their preparation
US3915996A (en) * 1972-10-16 1975-10-28 Abbott Lab Process for making benzopyrans
US4025630A (en) * 1973-09-19 1977-05-24 Abbott Laboratories Anesthesia methods using benzopyrans and esters thereof as pre-anesthesia medication
US4292316A (en) * 1978-10-02 1981-09-29 Abbott Laboratories Antiglaucoma agents
US4198511A (en) * 1979-03-21 1980-04-15 Warner-Lambert Company 1,5-Dihydro-1,5-dioxo-N-1H-tetrazol-5-yl-4H-[1]benzopyrano[3,4-b]pyridine-3-carboxamides and process thereof
US4210758A (en) * 1979-03-21 1980-07-01 Warner-Lambert Company 1,5-Dihydro-1,5-dioxo-N-1H-tetrazol-5-yl-4H-[1]benzopyrano[3,4-b]pyridine-2-carboxamides
JPS5746903A (en) * 1980-09-05 1982-03-17 Mitsubishi Chem Ind Ltd Agricultural and gardening fungicide
NL8005754A (nl) * 1980-10-18 1982-05-17 Akzo Nv Benzo 4,5 pyrano 2,3-c pyrrool derivaten.
US4420480A (en) * 1981-11-20 1983-12-13 Merck & Co., Inc. Hexahydronaphth[1,2-b]-1,4-oxazines
US4540691A (en) * 1984-04-13 1985-09-10 Nelson Research & Development Co. Dopamine agonists and use thereof
US4666916A (en) * 1985-11-08 1987-05-19 Ciba-Geigy Corporation Hexahydro-(1)-benzo-(pyrano and thiopyrano) (4,3-C)pyridines, useful as serotin-2 blocking agents

Also Published As

Publication number Publication date
GR851116B (da) 1985-11-25
US4604397A (en) 1986-08-05
FI851802L (fi) 1985-11-11
EP0161218A3 (en) 1987-03-04
JPH0443917B2 (da) 1992-07-20
DE3583307D1 (en) 1991-08-01
NO162860B (no) 1989-11-20
DK205285D0 (da) 1985-05-09
EP0161218B1 (de) 1991-06-26
ES542929A0 (es) 1987-07-01
ES555529A0 (es) 1988-01-01
AR243526A1 (es) 1993-08-31
FI83652B (fi) 1991-04-30
ES8801279A1 (es) 1988-01-01
FI851802A0 (fi) 1985-05-08
AU592308B2 (en) 1990-01-11
FI83652C (fi) 1991-08-12
JPS60243090A (ja) 1985-12-03
AU4224885A (en) 1985-11-14
ES8706687A1 (es) 1987-07-01
ES8801280A1 (es) 1988-01-01
NO162860C (no) 1990-02-28
NZ212031A (en) 1988-08-30
ES8801282A1 (es) 1988-01-01
ES555530A0 (es) 1988-01-01
IE851155L (en) 1985-11-10
ZA853507B (en) 1985-12-24
HUT37939A (en) 1986-03-28
EP0161218A2 (de) 1985-11-13
ES555528A0 (es) 1988-01-01
CA1298582C (en) 1992-04-07
PT80415B (en) 1987-04-16
ES8801281A1 (es) 1988-01-01
DK168571B1 (da) 1994-04-25
IE57978B1 (en) 1993-06-02
DK205285A (da) 1985-11-11
IL75135A0 (en) 1985-09-29
NO851846L (no) 1985-11-11
ATE64735T1 (de) 1991-07-15
PT80415A (en) 1985-06-01
IL75135A (en) 1989-07-31
ES555527A0 (es) 1988-01-01
HU199476B (en) 1990-02-28

Similar Documents

Publication Publication Date Title
EP0683166B1 (de) 3-Indolylpiperidine
EP0736525B1 (de) Benzonitrile als 5-HT Agonisten und Antagonisten
EP0280269B1 (de) 3-Amino-dihydro-[1]-benzopyrane und Benzothiopyrane
DD273833A5 (de) N 9 - cyclopentylsubstituierte adeninderivate
EP0161218B1 (de) Benzo-(pyrano und thiopyrano)-pyridine
EP0722942A1 (de) Indolpiperidin-Derivate
DD155988A5 (de) Verfahren zur herstellung von 2-acylaminomethyl-1,4-benzodiazepine und deren salze
DE3023626A1 (de) 1,9-dihydroxyoctahydrobenzo eckige klammer auf c eckige klammer zu chinoline und 1-hydroxyhexahydrobenzo eckige klammer auf c eckige klammer zu chinolin-9 (8h)- one als antiemetika
WO2003037863A2 (de) Substituierte indole, verfahren zu deren herstellung und deren verwendung zur schmerzbekämpfung
EP0252005A1 (de) Hydrierte 1-Benzooxacycloalkyl-pyridincarbonsäureverbindungen
DE2165276A1 (de) 8-Benzofurylmethyl-l,3,8-triazaspiro (4,5) dekane
DD263289A5 (de) Verfahren zur herstellung disubstituierter piperazine
DE2719294A1 (de) Neue derivate des 1,4-benzodioxans, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
EP0266308B1 (de) Indolo-pyrazino-benzodiazepin-Derivate
DE19932314A1 (de) Benzofuranderivate
DE102005062098A1 (de) Oxaphenanthren-Derivate
DE3300522C2 (da)
EP0389425A1 (de) Neue Benzothiopyranylamine
EP0068240B1 (de) 2-Acylaminomethyl-1,4-benzodiazepin-Verbindungen sowie Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US4721787A (en) Process for the preparation of benzo-(pyrano and thiopyrano)-pyridines
EP0017727A1 (de) Polysubstituierte Diazatricyclen, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
DE69907636T2 (de) 2-aminochinolinderivate mit d4-agonistischer wirkung
CH625789A5 (da)
EP0187619A2 (de) 1,3-disubstituierte Tetrahydropyridine
EP0241654B1 (de) Hydroxyindolester

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee