ES555528A0 - Procedimiento para la obtencion de benzo-(pirano y tiopirano)-piridinas - Google Patents

Procedimiento para la obtencion de benzo-(pirano y tiopirano)-piridinas

Info

Publication number
ES555528A0
ES555528A0 ES555528A ES555528A ES555528A0 ES 555528 A0 ES555528 A0 ES 555528A0 ES 555528 A ES555528 A ES 555528A ES 555528 A ES555528 A ES 555528A ES 555528 A0 ES555528 A0 ES 555528A0
Authority
ES
Spain
Prior art keywords
thiopirano
piridinas
pyrano
benzo
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES555528A
Other languages
English (en)
Other versions
ES8801280A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES555528A0 publication Critical patent/ES555528A0/es
Publication of ES8801280A1 publication Critical patent/ES8801280A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06Benzothiopyrans; Hydrogenated benzothiopyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
ES555528A 1984-05-10 1986-05-30 Procedimiento para la obtencion de benzo-(pirano y tiopirano)-piridinas Expired ES8801280A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60903784A 1984-05-10 1984-05-10

Publications (2)

Publication Number Publication Date
ES555528A0 true ES555528A0 (es) 1988-01-01
ES8801280A1 ES8801280A1 (es) 1988-01-01

Family

ID=24439108

Family Applications (5)

Application Number Title Priority Date Filing Date
ES542929A Expired ES8706687A1 (es) 1984-05-10 1985-05-08 Procedimiento para la obtencion de benzo-(pirano y tiopira- no)-piridinas
ES555527A Expired ES8801279A1 (es) 1984-05-10 1986-05-30 Procedimiento para la obtencion de benzo-(pirano y tiopirano)-piridinas
ES555528A Expired ES8801280A1 (es) 1984-05-10 1986-05-30 Procedimiento para la obtencion de benzo-(pirano y tiopirano)-piridinas
ES555529A Expired ES8801281A1 (es) 1984-05-10 1986-05-30 Procedimiento para la obtencion de benzo-(pirano y tiopirano)-piridinas
ES555530A Expired ES8801282A1 (es) 1984-05-10 1986-05-30 Procedimiento para la obtencion de benzo-(pirano y tiopirano)-piridinas

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES542929A Expired ES8706687A1 (es) 1984-05-10 1985-05-08 Procedimiento para la obtencion de benzo-(pirano y tiopira- no)-piridinas
ES555527A Expired ES8801279A1 (es) 1984-05-10 1986-05-30 Procedimiento para la obtencion de benzo-(pirano y tiopirano)-piridinas

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES555529A Expired ES8801281A1 (es) 1984-05-10 1986-05-30 Procedimiento para la obtencion de benzo-(pirano y tiopirano)-piridinas
ES555530A Expired ES8801282A1 (es) 1984-05-10 1986-05-30 Procedimiento para la obtencion de benzo-(pirano y tiopirano)-piridinas

Country Status (20)

Country Link
US (1) US4604397A (es)
EP (1) EP0161218B1 (es)
JP (1) JPS60243090A (es)
AR (1) AR243526A1 (es)
AT (1) ATE64735T1 (es)
AU (1) AU592308B2 (es)
CA (1) CA1298582C (es)
DD (1) DD235872A5 (es)
DE (1) DE3583307D1 (es)
DK (1) DK168571B1 (es)
ES (5) ES8706687A1 (es)
FI (1) FI83652C (es)
GR (1) GR851116B (es)
HU (1) HU199476B (es)
IE (1) IE57978B1 (es)
IL (1) IL75135A (es)
NO (1) NO162860C (es)
NZ (1) NZ212031A (es)
PT (1) PT80415B (es)
ZA (1) ZA853507B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8426584D0 (en) * 1984-10-19 1984-11-28 Beecham Group Plc Compounds
US4666916A (en) * 1985-11-08 1987-05-19 Ciba-Geigy Corporation Hexahydro-(1)-benzo-(pyrano and thiopyrano) (4,3-C)pyridines, useful as serotin-2 blocking agents
US4792548A (en) * 1986-05-21 1988-12-20 Warner-Lambert Company Trans-benzopyran-(4,3-b)-1,4-oxazine derivatives, intermediates and pharmaceutical use
US4801605A (en) * 1986-08-29 1989-01-31 Ciba-Geigy Corporation 3-amino-dihydro-[1]-benzopyrans and benzothiopyrans
FR2619112B1 (fr) * 1987-08-07 1989-11-17 Synthelabo Derives de (piperidinyl-4)methyl-2 benzo(b)furo(2,3-c) pyridines, leur preparation et leur application en therapeutique
US4992465A (en) * 1988-09-27 1991-02-12 Ciba-Geigy Corporation 3-amino-dihydro-(1)-benzopyrans
US5962463A (en) * 1992-10-09 1999-10-05 Massachusetts Institute Of Technology Methods of stimulating non-amyloidogenic processing of the amyloid precursor protein
FR2721027B1 (fr) * 1994-06-08 1996-07-19 Adir Nouveaux dérivés tétracycliques de la 1,4-oxazine, leur procédé de préparation et les compositions pharmaceutiques les contenant.
FR2741074B1 (fr) 1995-11-09 1997-12-19 Adir Nouveaux composes tetracycliques de la 1,4-oxazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6342533B1 (en) 1998-12-01 2002-01-29 Sepracor, Inc. Derivatives of (−)-venlafaxine and methods of preparing and using the same
CA2368083A1 (en) * 1999-04-06 2000-10-12 Sepracor Inc. Derivatives of venlafaxine and methods of preparing and using the same
WO2005032485A2 (en) * 2003-10-03 2005-04-14 Psychogenics, Inc. Compounds and methods for the treatment of attention-deficit hyperactivity disorder
CN101257898A (zh) * 2005-07-06 2008-09-03 塞普拉科公司 艾司佐匹克隆与o-去甲基文拉法辛的组合以及治疗绝经期和心境障碍、焦虑症和认知障碍的方法
BRPI1003506B1 (pt) 2010-09-24 2019-12-03 Ache Int Bvi Ltd composto alquil-piperazino-fenil-4(3h)quinazolinonas e uso do composto alquil-piperazino-fenil-4(3h)quinazolinonas associado aos receptores serotoninérgicos 5-ht1a e 5-ht2a

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143819A (es) * 1965-09-27
US3514464A (en) * 1967-05-29 1970-05-26 Little Inc A 5-oxo-1,2,3,4-tetrahydro-5h-(1)benzopyrano(3,4-c)pyridines
US3689497A (en) * 1971-03-09 1972-09-05 Warner Lambert Co Substituted benzopyrano (3,4-b) pyridines and process for their preparation
US3915996A (en) * 1972-10-16 1975-10-28 Abbott Lab Process for making benzopyrans
US4025630A (en) * 1973-09-19 1977-05-24 Abbott Laboratories Anesthesia methods using benzopyrans and esters thereof as pre-anesthesia medication
US4292316A (en) * 1978-10-02 1981-09-29 Abbott Laboratories Antiglaucoma agents
US4210758A (en) * 1979-03-21 1980-07-01 Warner-Lambert Company 1,5-Dihydro-1,5-dioxo-N-1H-tetrazol-5-yl-4H-[1]benzopyrano[3,4-b]pyridine-2-carboxamides
US4198511A (en) * 1979-03-21 1980-04-15 Warner-Lambert Company 1,5-Dihydro-1,5-dioxo-N-1H-tetrazol-5-yl-4H-[1]benzopyrano[3,4-b]pyridine-3-carboxamides and process thereof
JPS5746903A (en) * 1980-09-05 1982-03-17 Mitsubishi Chem Ind Ltd Agricultural and gardening fungicide
NL8005754A (nl) * 1980-10-18 1982-05-17 Akzo Nv Benzo 4,5 pyrano 2,3-c pyrrool derivaten.
US4420480A (en) * 1981-11-20 1983-12-13 Merck & Co., Inc. Hexahydronaphth[1,2-b]-1,4-oxazines
US4540691A (en) * 1984-04-13 1985-09-10 Nelson Research & Development Co. Dopamine agonists and use thereof
US4666916A (en) * 1985-11-08 1987-05-19 Ciba-Geigy Corporation Hexahydro-(1)-benzo-(pyrano and thiopyrano) (4,3-C)pyridines, useful as serotin-2 blocking agents

Also Published As

Publication number Publication date
ES8801281A1 (es) 1988-01-01
EP0161218B1 (de) 1991-06-26
ES8801279A1 (es) 1988-01-01
NO162860B (no) 1989-11-20
NZ212031A (en) 1988-08-30
FI83652C (fi) 1991-08-12
PT80415B (en) 1987-04-16
HUT37939A (en) 1986-03-28
ES555530A0 (es) 1988-01-01
HU199476B (en) 1990-02-28
EP0161218A3 (en) 1987-03-04
ES555529A0 (es) 1988-01-01
NO851846L (no) 1985-11-11
IE57978B1 (en) 1993-06-02
ATE64735T1 (de) 1991-07-15
AU4224885A (en) 1985-11-14
CA1298582C (en) 1992-04-07
ES8801280A1 (es) 1988-01-01
DE3583307D1 (en) 1991-08-01
US4604397A (en) 1986-08-05
ES555527A0 (es) 1988-01-01
DK168571B1 (da) 1994-04-25
DD235872A5 (de) 1986-05-21
DK205285D0 (da) 1985-05-09
DK205285A (da) 1985-11-11
ES8801282A1 (es) 1988-01-01
IL75135A0 (en) 1985-09-29
JPH0443917B2 (es) 1992-07-20
FI851802A0 (fi) 1985-05-08
GR851116B (es) 1985-11-25
IL75135A (en) 1989-07-31
ES542929A0 (es) 1987-07-01
FI83652B (fi) 1991-04-30
IE851155L (en) 1985-11-10
EP0161218A2 (de) 1985-11-13
AR243526A1 (es) 1993-08-31
ES8706687A1 (es) 1987-07-01
JPS60243090A (ja) 1985-12-03
ZA853507B (en) 1985-12-24
FI851802L (fi) 1985-11-11
AU592308B2 (en) 1990-01-11
PT80415A (en) 1985-06-01
NO162860C (no) 1990-02-28

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519