DD215550A5 - Verfahren zur herstellung neuer imidazo/1,2-a/pyrimidine - Google Patents

Verfahren zur herstellung neuer imidazo/1,2-a/pyrimidine Download PDF

Info

Publication number
DD215550A5
DD215550A5 DD83254274A DD25427483A DD215550A5 DD 215550 A5 DD215550 A5 DD 215550A5 DD 83254274 A DD83254274 A DD 83254274A DD 25427483 A DD25427483 A DD 25427483A DD 215550 A5 DD215550 A5 DD 215550A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
group
compound
alkyl
ethyl
Prior art date
Application number
DD83254274A
Other languages
German (de)
English (en)
Inventor
Wilfred R Tully
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838303612A external-priority patent/GB8303612D0/en
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of DD215550A5 publication Critical patent/DD215550A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DD83254274A 1982-08-27 1983-08-26 Verfahren zur herstellung neuer imidazo/1,2-a/pyrimidine DD215550A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8224606 1982-08-27
GB838303612A GB8303612D0 (en) 1983-02-09 1983-02-09 Imidazo 1,2-a pyrimidines

Publications (1)

Publication Number Publication Date
DD215550A5 true DD215550A5 (de) 1984-11-14

Family

ID=26283682

Family Applications (1)

Application Number Title Priority Date Filing Date
DD83254274A DD215550A5 (de) 1982-08-27 1983-08-26 Verfahren zur herstellung neuer imidazo/1,2-a/pyrimidine

Country Status (19)

Country Link
US (2) US4532243A (pt)
EP (1) EP0104104B1 (pt)
KR (1) KR890003000B1 (pt)
AR (1) AR241020A1 (pt)
AU (1) AU559419B2 (pt)
CA (1) CA1228589A (pt)
DD (1) DD215550A5 (pt)
DE (1) DE3366467D1 (pt)
DK (1) DK390583A (pt)
ES (1) ES8506314A1 (pt)
FI (1) FI74010C (pt)
GB (1) GB2128989B (pt)
GR (1) GR79375B (pt)
IE (1) IE55900B1 (pt)
IL (1) IL69417A (pt)
NZ (1) NZ205387A (pt)
PH (1) PH20037A (pt)
PT (1) PT77258B (pt)
SU (1) SU1287752A3 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL69417A (en) * 1982-08-27 1987-12-20 Roussel Uclaf 2-acyl imidazo(1,2-a)pyrimidines,their preparation and pharmaceutical compositions containing them
GB8334210D0 (en) * 1983-12-22 1984-02-01 Roussel Lab Ltd Imidazo(1 2-c)pyrimidines
GB8432073D0 (en) * 1984-12-19 1985-01-30 Roussel Lab Ltd Chemical compounds
GB8613591D0 (en) * 1986-06-04 1986-07-09 Roussel Lab Ltd Chemical compounds
GB8620060D0 (en) * 1986-08-18 1986-10-01 Roussel Lab Ltd Chemical compounds
US4731446A (en) * 1987-05-01 1988-03-15 The Dow Chemical Company Imidazo[1,2-a]pyrimidine sulfonic acids and acid halides
GB8712466D0 (en) * 1987-05-27 1987-07-01 Roussel Lab Ltd Chemical compounds
GB8719368D0 (en) * 1987-08-15 1987-09-23 Wellcome Found Heterocyclic compounds
US5302586A (en) * 1991-12-19 1994-04-12 G. D. Searle & Co. Phosphonomethyl-imidazo[1,2-a]pyrimidine-2-carboxylic acid compounds for treatment of neurotoxic injury
IL156813A0 (en) * 2001-01-26 2004-02-08 Bristol Myers Squibb Co Imidazolyl derivatives and pharmaceutical compositions containing the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3594379A (en) * 1968-09-16 1971-07-20 Sandoz Ag 2,3-dihydroimidazo(1,2-c)quinazolines
US4223031A (en) * 1978-05-05 1980-09-16 Mead Johnson & Company Azolopyrimidinones
US4236005A (en) * 1979-07-02 1980-11-25 American Cyanamid Company Imidazo[1,5-a]pyrimidines
FR2502622A1 (fr) * 1981-03-25 1982-10-01 Synthelabo Derives d'imidazo (1,2-a) pyrimidines, leur preparation et leur application en therapeutique
US4374988A (en) * 1981-11-05 1983-02-22 American Cyanamid Company 4-Heteroarylimidazo-[1,5-A]pyrimidines
IL69417A (en) * 1982-08-27 1987-12-20 Roussel Uclaf 2-acyl imidazo(1,2-a)pyrimidines,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
GB8322993D0 (en) 1983-09-28
KR840005812A (ko) 1984-11-19
AR241020A2 (es) 1991-04-30
FI833055A (fi) 1984-02-28
KR890003000B1 (ko) 1989-08-18
IL69417A0 (en) 1983-11-30
FI74010C (fi) 1987-12-10
ES525186A0 (es) 1985-07-01
SU1287752A3 (ru) 1987-01-30
PT77258A (en) 1983-09-01
DK390583D0 (da) 1983-08-26
FI74010B (fi) 1987-08-31
FI833055A0 (fi) 1983-08-26
DK390583A (da) 1984-02-28
GB2128989A (en) 1984-05-10
GR79375B (pt) 1984-10-22
PH20037A (en) 1986-09-04
AR241020A1 (es) 1991-04-30
EP0104104A1 (fr) 1984-03-28
ES8506314A1 (es) 1985-07-01
PT77258B (en) 1986-03-21
AU559419B2 (en) 1987-03-12
US4588720A (en) 1986-05-13
IL69417A (en) 1987-12-20
EP0104104B1 (fr) 1986-09-24
DE3366467D1 (en) 1986-10-30
GB2128989B (en) 1986-03-19
US4532243A (en) 1985-07-30
IE832001L (en) 1984-02-27
CA1228589A (en) 1987-10-27
IE55900B1 (en) 1991-02-14
NZ205387A (en) 1986-06-11
AU1846183A (en) 1984-03-01

Similar Documents

Publication Publication Date Title
DE69916578T2 (de) Pyrazolotriazine als crf-antagonisten
EP0374808B1 (de) Neue Xanthinderivate mit Adenosin-antagonistischer Wirkung
DE2265617C3 (de) 5-Chlor-2- [3-(aminomethyl)-5-methyl-4H-1.2.4-triazol-4-yl]-benzophenone
EP0682027B1 (de) Pyrrolopyrimidinderivate mit antiproliferativer Wirkung
DE60020994T2 (de) Neue verwendung sowie neue n-azabicycloamid-verbindungen
DE2903653A1 (de) Imidazolderivate oder deren salze, sie enthaltende pharmazeutische zubereitungen, sowie verfahren zu ihrer herstellung
DE1957711A1 (de) 1-H-Imidazo[4,5-b]pyrazin-2-one und Verfahren zu deren Herstellung
DE19744027A1 (de) Substituierte Pyrazolo[3,4-b]pyridine, ihre Herstellung und Verwendung in Arzneimitteln
IE49077B1 (en) 5-(4-pyridyl)-6-(4-fluorophenyl)-2,3-dihydroimidazo(2,1-b)thiazole,process for its preparation and medical composition
DE2237765A1 (de) Neue aminoderivate von pyrazolo (3,4-b)pyridin-5-carbonsaeuren mit deren estern und salzen, verfahren zu ihrer herstellung und ihre verwendung
EP1628980B1 (de) 6-arylmethyl-substituierte pyrazolopyrimidine
DD215550A5 (de) Verfahren zur herstellung neuer imidazo/1,2-a/pyrimidine
WO1991009858A1 (de) NEUE β-CARBOLINE, VERFAHREN ZU DEREN HERSTELLUNG UND DEREN VERWENDUNG IN ARZNEIMITTELN
DE19636769A1 (de) 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE2130408A1 (de) Pharmazeutische Zusammensetzungen
DE3343922A1 (de) Gewisse substituierte pyrazolochinoline, verfahren zu ihrer herstellung, pharmazeutische praeparate enthaltend diese verbindungen und ihre therapeutische anwendung
EP2655360B1 (de) Verfahren zur herstellung von n-sulfonylsubstituierten oxindolen
DE2604748A1 (de) Aminoderivate von imidazo(4,5-b) pyridinen
DD266355A5 (de) Verfahren zur herstellung von neuen 1,4-benzodiozepinen
DD216022A5 (de) Verfahren zur herstellung einer neuen heterocyclischen verbindung
DE69612037T2 (de) Thiopyran Derivate
DD236928A5 (de) Verfahren zur herstellung neuer 1,2,4-triazolo-carbamate
DE3785987T2 (de) Imidazol-derivate und deren salze, verfahren zu deren herstellung, deren anwendung als arzneimittel und deren zusammensetzungen.
DE2301268A1 (de) Neue pyrazolopyridine
DE2928219A1 (de) Optisch aktive oder racemische 10-brom-14-oxo-e-homoeburnanderivate, 1-alkyl-9-bromhexahydroindolochinoliziniumderivate, 1-alkyl-1-(2'-alkoxycarbonylaethyl)-9-brom-1,2,3,4,6,7,12,12b-octahydroindolo eckige klammer auf 2,3-a eckige klammer zu chinolizin- bzw. 1-alkyl-1 -(2'-carboxyaethyl)-9-brom-1,2,3,4,6,7, 12,12b-octahydroindolo eckige klammer auf 2,3-a eckige klammer zu chinolizinderivate und 5-bromtryptamin-2-carbonsaeurederivate, verfahren zur herstellung derselben und von optisch aktiven oder racemischen 10-bromvincaminsaeureesterderivaten und optisch aktive oder racemische 10-bromvincaminsaeureesterderivate sowie erstere oder letztere enthaltende arzneimittel

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee