DD210258A5 - Verfahren zur herstellung von a-21978c-cyclopeptidderivaten - Google Patents

Verfahren zur herstellung von a-21978c-cyclopeptidderivaten Download PDF

Info

Publication number
DD210258A5
DD210258A5 DD83251130A DD25113083A DD210258A5 DD 210258 A5 DD210258 A5 DD 210258A5 DD 83251130 A DD83251130 A DD 83251130A DD 25113083 A DD25113083 A DD 25113083A DD 210258 A5 DD210258 A5 DD 210258A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
amino
group
alkyl
aminoacyl
Prior art date
Application number
DD83251130A
Other languages
German (de)
English (en)
Inventor
Manuel Debono
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DD210258A5 publication Critical patent/DD210258A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/045Actinoplanes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/19Antibiotic
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/27Cyclic peptide or cyclic protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DD83251130A 1982-05-21 1983-05-20 Verfahren zur herstellung von a-21978c-cyclopeptidderivaten DD210258A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/380,499 US4396543A (en) 1982-05-21 1982-05-21 Derivatives of A-21978C cyclic peptides

Publications (1)

Publication Number Publication Date
DD210258A5 true DD210258A5 (de) 1984-06-06

Family

ID=23501405

Family Applications (1)

Application Number Title Priority Date Filing Date
DD83251130A DD210258A5 (de) 1982-05-21 1983-05-20 Verfahren zur herstellung von a-21978c-cyclopeptidderivaten

Country Status (14)

Country Link
US (1) US4396543A (https=)
KR (1) KR860002193B1 (https=)
AT (1) AT381104B (https=)
CA (1) CA1216580A (https=)
DD (1) DD210258A5 (https=)
DK (1) DK221283A (https=)
ES (1) ES8407011A1 (https=)
FI (1) FI831747A7 (https=)
GR (1) GR78850B (https=)
HU (1) HU193528B (https=)
PH (1) PH23417A (https=)
PL (1) PL242097A1 (https=)
PT (1) PT76702B (https=)
RO (1) RO86723B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4977083A (en) * 1988-04-11 1990-12-11 Eli Lilly And Company Processes for preparing A54145 compounds
DE69739532D1 (de) * 1996-03-08 2009-09-24 Astellas Pharma Inc Prozess für die deacylierung von zyklischen lipopeptiden.
CN1425025A (zh) 1999-12-15 2003-06-18 卡比斯特制药公司 作为抗菌剂的新颖的脂肽
MXPA02006028A (es) * 1999-12-15 2004-08-23 Cubist Pharm Inc Lipopeptidos novedosos como agentes antibacterianos.
WO2001044274A1 (en) * 1999-12-15 2001-06-21 Cubist Pharmaceuticals, Inc. Lipopeptides as antibacterial agents
AU2002303480A1 (en) * 2001-04-25 2002-11-05 Wyeth Holdings Corporation Glycopeptide antibiotics
BRPI0923567A2 (pt) * 2008-12-22 2016-09-27 Cubist Pharm Inc agentes antibactericidas novos para o tratamento de infecções gram positivas
US11174288B2 (en) 2016-12-06 2021-11-16 Northeastern University Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3150059A (en) * 1962-12-26 1964-09-22 Lilly Co Eli Penicillin deacylation via actinoplanaceae fermentation
US4050989A (en) * 1974-12-05 1977-09-27 Eisai Co., Ltd. Process of preparing desacyl-pepsidine with bacillus pumilus
US4208403A (en) * 1978-10-16 1980-06-17 Eli Lilly And Company A-21978 Antibiotics and process for their production
US4293485A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of S31794/F-1 nucleus
US4293483A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
US4293488A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912B nucleus
US4293491A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912H nucleus
US4293482A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company A-30912A Nucleus
US4293487A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912D nucleus

Also Published As

Publication number Publication date
GR78850B (https=) 1984-10-02
HU193528B (en) 1987-10-28
US4396543A (en) 1983-08-02
AT381104B (de) 1986-08-25
RO86723A (ro) 1985-04-17
KR860002193B1 (ko) 1986-12-30
KR840005077A (ko) 1984-11-03
PL242097A1 (en) 1984-07-02
ATA178483A (de) 1986-01-15
FI831747A0 (fi) 1983-05-18
PT76702B (en) 1986-03-27
PT76702A (en) 1983-06-01
DK221283A (da) 1983-11-22
RO86723B (ro) 1985-05-01
ES522559A0 (es) 1984-09-01
FI831747L (fi) 1983-11-22
ES8407011A1 (es) 1984-09-01
FI831747A7 (fi) 1983-11-22
CA1216580A (en) 1987-01-13
DK221283D0 (da) 1983-05-18
PH23417A (en) 1989-08-07

Similar Documents

Publication Publication Date Title
DE69122432T2 (de) Zyklisches Polypeptid mit antibiotischer Aktivität, dessen Herstellung und Reinkultur eines Coelomycetes Stammes
DE3782720T2 (de) Glykopeptid-antibiotika.
DE68905119T2 (de) Methode zur kontrolle von pneumocystis carinii.
EP0629636A1 (de) Lipopeptide aus Actinoplanes sp. mit pharmakologischer Wirkung, Verfahren zu ihrer Herstellung und Verwendung derselben
DE3780644T2 (de) Glykopeptid-antibiotika.
USRE32311E (en) Derivatives of A-21978C cyclic peptides
DD146618A5 (de) Verfahren zur herstellung des antibiotikums
DD209810A5 (de) Verfahren zur herstellung von a-21978c-cyclopeptidderivaten
EP0362520B1 (de) Ein neues Antibiotikum, Mersacidin, ein Verfahren zur seiner Herstellung und seine Verwendung als Arzneimittel
DE68914021T2 (de) Antibiotika TAN-1057.
EP0916680B1 (de) Lantibiotikum verwandt mit Actagardine, Verfahren zur Herstellung und Verwendung desselben
DE68925806T2 (de) C63-Amidderivate von 34-de(acetylglucosaminyl)-34-deoxy-teicoplaninen
DD210258A5 (de) Verfahren zur herstellung von a-21978c-cyclopeptidderivaten
NZ204249A (en) A-21978c cyclic peptide derivatives and antimicrobial compositions
DE3886718T2 (de) Hydrogenierte Derivate von Antibiotika A/16686.
DE69108972T2 (de) Antibiotika GE 2270 Faktoren B1, B2, C1, D1, D2, E und T.
DE68920898T2 (de) Aglykone von A/16686-Antibiotika.
DE3885394T2 (de) Teicoplaninähnliche Derivate.
EP0521408B1 (de) Balhimycin-abgeleitete glykopeptidische Antibiotika
DE68925540T2 (de) Peptid-Antibiotika
DE69224497T2 (de) Faktor C2a des Antibiotikums CE 2270
EP0005956A1 (en) A-38533 antibiotics, their preparation, formulations containing them, and micro-organism employed in their production
DE69709802T2 (de) Amythiamicin Amid-Derivate
DE69317058T2 (de) Die antibiotika ge 37468 a, b und c
DE3887292T2 (de) Antibiotische Verbindungen, genannt A/16686-Faktoren A'1,A'2 und A'3.