MXPA02006028A - Lipopeptidos novedosos como agentes antibacterianos. - Google Patents

Lipopeptidos novedosos como agentes antibacterianos.

Info

Publication number
MXPA02006028A
MXPA02006028A MXPA02006028A MXPA02006028A MXPA02006028A MX PA02006028 A MXPA02006028 A MX PA02006028A MX PA02006028 A MXPA02006028 A MX PA02006028A MX PA02006028 A MXPA02006028 A MX PA02006028A MX PA02006028 A MXPA02006028 A MX PA02006028A
Authority
MX
Mexico
Prior art keywords
compounds
daptomycin
analogs
antibacterial agents
relates
Prior art date
Application number
MXPA02006028A
Other languages
English (en)
Inventor
Yan Zhang
Original Assignee
Cubist Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cubist Pharm Inc filed Critical Cubist Pharm Inc
Publication of MXPA02006028A publication Critical patent/MXPA02006028A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invencion se relaciona con compuestos lipopeptidicos novedosos. La invencion tambien se relaciona con composiciones farmaceuticas de estos compuestos y los metodos para utilizar estos compuestos como compuestos antibacterianos. La invencion tambien se relaciona con los metodos para producir estos compuestos lipopeptidicos novedosos y los intermediarios utilizados para producir estos compuestos.
MXPA02006028A 1999-12-15 2000-12-15 Lipopeptidos novedosos como agentes antibacterianos. MXPA02006028A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17094599P 1999-12-15 1999-12-15
PCT/US2000/034051 WO2001044271A2 (en) 1999-12-15 2000-12-15 Daptomycin analogs and their use as antibacterial agents

Publications (1)

Publication Number Publication Date
MXPA02006028A true MXPA02006028A (es) 2004-08-23

Family

ID=22621920

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02006028A MXPA02006028A (es) 1999-12-15 2000-12-15 Lipopeptidos novedosos como agentes antibacterianos.

Country Status (13)

Country Link
US (1) US6794490B2 (es)
EP (1) EP1240182A2 (es)
JP (1) JP2003517003A (es)
KR (1) KR20020063230A (es)
CN (1) CN1423655A (es)
AU (1) AU784942B2 (es)
BR (1) BR0017028A (es)
CA (1) CA2394313A1 (es)
IL (1) IL150224A0 (es)
MX (1) MXPA02006028A (es)
NO (1) NO20022886L (es)
WO (1) WO2001044271A2 (es)
ZA (1) ZA200205113B (es)

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US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
CA2301336A1 (en) * 2000-03-17 2001-09-17 Michael T. Kelly Topical treatment of rosacea
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
ES2377931T5 (es) 2000-12-18 2015-11-04 Cubist Pharmaceuticals, Inc. Métodos para preparar lipopéptidos purificados
EP1932853A1 (en) 2001-08-06 2008-06-18 Cubist Pharmaceutical Inc. Novel depsipeptides and process for preparing same
EP1423414A4 (en) 2001-08-06 2005-11-30 Cubist Pharm Inc NEW DEPSIPEPTIDES AND METHOD FOR THE PRODUCTION THEREOF
US6767718B2 (en) 2002-05-10 2004-07-27 Biosource Pharm, Inc. Lipodepsipeptide antibiotics and methods of preparation
WO2003099217A2 (en) * 2002-05-23 2003-12-04 Activbiotics, Inc. Methods of treating bacterial infections and diseases associated therewith
US20090149453A1 (en) * 2002-05-23 2009-06-11 Activbiotics Pharma Llc Methods and compositions for treating bacterial infections and diseases associated therewith
US20040077533A1 (en) * 2002-05-23 2004-04-22 Sayada Chalom B. Methods and compositions for treating bacterial infections and diseases associated therewith
US7317001B2 (en) 2002-06-06 2008-01-08 Oscient Pharmaceuticals Corporation Use of ramoplanin to treat diseases associated with the use of antibiotics
IL150907A (en) * 2002-07-25 2007-07-04 Stephan Cherkez Process for the preparation of stable amorphous calcium pseudomonate
US7671011B2 (en) * 2003-06-19 2010-03-02 Yeda Research & Development Co. Ltd. Antimicrobial and anticancer lipopeptides
US20050123602A1 (en) * 2003-09-25 2005-06-09 Michaelis Arthur F. Rifalazil formulations
SE0303588D0 (sv) 2003-12-30 2003-12-30 Bioactive Polymers Ab C O Lund Surface protection of exposed biological tissues
ES2305897T3 (es) * 2003-12-30 2008-11-01 Bioactive Polymers Ab Proteccion de superficie de tejidos biologicos expuestos.
WO2005089236A2 (en) 2004-03-13 2005-09-29 Cluster Resources, Inc. System and method for providing intelligent pre-staging of data in a compute environment
US8782654B2 (en) 2004-03-13 2014-07-15 Adaptive Computing Enterprises, Inc. Co-allocating a reservation spanning different compute resources types
US20070266388A1 (en) 2004-06-18 2007-11-15 Cluster Resources, Inc. System and method for providing advanced reservations in a compute environment
US20060004185A1 (en) 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
US8176490B1 (en) 2004-08-20 2012-05-08 Adaptive Computing Enterprises, Inc. System and method of interfacing a workload manager and scheduler with an identity manager
US8271980B2 (en) 2004-11-08 2012-09-18 Adaptive Computing Enterprises, Inc. System and method of providing system jobs within a compute environment
CA2587848A1 (en) * 2004-11-12 2006-10-19 Cubist Pharmaceuticals, Inc. Antiinfective lipopeptides
US20080051326A1 (en) * 2004-11-12 2008-02-28 Alexander Dylan C Antiinfective Lipopeptides
US20080171766A1 (en) * 2005-03-10 2008-07-17 Smithkline Beecham Corporation Novel Method
US8863143B2 (en) 2006-03-16 2014-10-14 Adaptive Computing Enterprises, Inc. System and method for managing a hybrid compute environment
US9231886B2 (en) 2005-03-16 2016-01-05 Adaptive Computing Enterprises, Inc. Simple integration of an on-demand compute environment
ES2614751T3 (es) 2005-04-07 2017-06-01 Iii Holdings 12, Llc Acceso bajo demanda a recursos informáticos
US8968781B2 (en) * 2005-04-29 2015-03-03 Cubist Pharmaceuticals, Inc. Therapeutic compositions
EP2018864A1 (en) 2007-07-23 2009-01-28 Biomet Deutschland GmbH Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition
US8041773B2 (en) 2007-09-24 2011-10-18 The Research Foundation Of State University Of New York Automatic clustering for self-organizing grids
PT2379580E (pt) * 2008-12-22 2014-01-20 Cubist Pharm Inc Novos agentes antibacterianos para o tratamento de infecções por bactérias gram positivas
TW201035111A (en) 2008-12-23 2010-10-01 Biosource Pharm Inc Antibiotic compositions for the treatment of gram negative infections
US11720290B2 (en) 2009-10-30 2023-08-08 Iii Holdings 2, Llc Memcached server functionality in a cluster of data processing nodes
US10877695B2 (en) 2009-10-30 2020-12-29 Iii Holdings 2, Llc Memcached server functionality in a cluster of data processing nodes
US8415307B1 (en) 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
WO2012011917A1 (en) * 2010-07-23 2012-01-26 Activbiotics Pharma, Llc Administration of rifalazil to immunocompromised patients
KR20140037877A (ko) * 2011-05-26 2014-03-27 큐비스트 파마슈티컬즈 인코포레이티드 Cb-183,315 조성물 및 관련 방법
WO2013039861A2 (en) 2011-09-12 2013-03-21 modeRNA Therapeutics Engineered nucleic acids and methods of use thereof
WO2013059610A1 (en) 2011-10-20 2013-04-25 Trius Therapeutics, Inc. Therapeutic combination of daptomycin and protein synthesis inhibitor antibiotic, and methods of use
EP2833892A4 (en) 2012-04-02 2016-07-20 Moderna Therapeutics Inc MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS AND PEPTIDES ASSOCIATED WITH ONCOLOGY
WO2013151666A2 (en) 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of biologics and proteins associated with human disease
WO2017083515A2 (en) 2015-11-10 2017-05-18 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
US10358463B2 (en) * 2016-04-05 2019-07-23 Bristol-Myers Squibb Company Immunomodulators
US11890319B2 (en) 2017-01-18 2024-02-06 Visterra, Inc. Antibody molecule-drug conjugates and uses thereof
KR20200020858A (ko) * 2017-06-23 2020-02-26 브리스톨-마이어스 스큅 컴퍼니 Pd-1의 길항제로서 작용하는 면역조정제
CN116710146A (zh) 2020-04-03 2023-09-05 威特拉公司 抗体分子-药物偶联物及其用途

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USRE32310E (en) 1982-05-21 1986-12-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4524135A (en) 1982-05-21 1985-06-18 Eli Lilly And Company A-21978C cyclic peptides
US4537717A (en) 1982-05-21 1985-08-27 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4399067A (en) 1982-05-21 1983-08-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
USRE32311E (en) 1982-05-21 1986-12-16 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
IL68700A0 (en) * 1982-05-21 1983-09-30 Lilly Co Eli Improvements relating to a-21978c cyclic peptide derivatives and their production
US4396543A (en) 1982-05-21 1983-08-02 Eli Lilly And Company Derivatives of A-21978C cyclic peptides
US4482487A (en) 1982-05-21 1984-11-13 Eli Lilly And Company A-21978C cyclic peptides
CA1315229C (en) 1987-06-10 1993-03-30 Patrick J. Baker Chromatographic purification process
EP0460882B1 (en) 1990-06-07 1996-07-24 Eli Lilly And Company Lipopeptide deacylase
DE4411025A1 (de) 1994-03-30 1995-10-05 Hoechst Ag Lipopeptid-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung
KR100545506B1 (ko) 1996-03-08 2006-10-04 아스테라스 세이야쿠 가부시키가이샤 환상 리포펩티드 물질의 탈아실화 방법
DE19807972A1 (de) 1998-02-25 1999-08-26 Hoechst Marion Roussel De Gmbh Lipopeptidantibiotika-Calciumsalze, Verfahren zu ihrer Herstellung und Verwendung

Also Published As

Publication number Publication date
ZA200205113B (en) 2003-11-26
NO20022886D0 (no) 2002-06-17
KR20020063230A (ko) 2002-08-01
AU3264001A (en) 2001-06-25
WO2001044271A2 (en) 2001-06-21
EP1240182A2 (en) 2002-09-18
CA2394313A1 (en) 2001-06-21
NO20022886L (no) 2002-08-02
WO2001044271A3 (en) 2002-03-07
JP2003517003A (ja) 2003-05-20
IL150224A0 (en) 2002-12-01
BR0017028A (pt) 2003-01-07
US20020058785A1 (en) 2002-05-16
CN1423655A (zh) 2003-06-11
AU784942B2 (en) 2006-08-03
US6794490B2 (en) 2004-09-21

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