KR860002193B1 - A-21978c 사이클릭 펩타이드 유도체의 제조방법 - Google Patents

A-21978c 사이클릭 펩타이드 유도체의 제조방법 Download PDF

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Publication number
KR860002193B1
KR860002193B1 KR1019830002223A KR830002223A KR860002193B1 KR 860002193 B1 KR860002193 B1 KR 860002193B1 KR 1019830002223 A KR1019830002223 A KR 1019830002223A KR 830002223 A KR830002223 A KR 830002223A KR 860002193 B1 KR860002193 B1 KR 860002193B1
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KR
South Korea
Prior art keywords
amino
formula
aminoacyl
alkyl
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019830002223A
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English (en)
Korean (ko)
Other versions
KR840005077A (ko
Inventor
데보노 마누엘
Original Assignee
일라이 릴리 앤드 캄파니
아더알. 웨일
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 일라이 릴리 앤드 캄파니, 아더알. 웨일 filed Critical 일라이 릴리 앤드 캄파니
Publication of KR840005077A publication Critical patent/KR840005077A/ko
Application granted granted Critical
Publication of KR860002193B1 publication Critical patent/KR860002193B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/045—Actinoplanes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/19—Antibiotic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
KR1019830002223A 1982-05-21 1983-05-19 A-21978c 사이클릭 펩타이드 유도체의 제조방법 Expired KR860002193B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US380499 1982-05-21
US06/380,499 US4396543A (en) 1982-05-21 1982-05-21 Derivatives of A-21978C cyclic peptides

Publications (2)

Publication Number Publication Date
KR840005077A KR840005077A (ko) 1984-11-03
KR860002193B1 true KR860002193B1 (ko) 1986-12-30

Family

ID=23501405

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830002223A Expired KR860002193B1 (ko) 1982-05-21 1983-05-19 A-21978c 사이클릭 펩타이드 유도체의 제조방법

Country Status (14)

Country Link
US (1) US4396543A (https=)
KR (1) KR860002193B1 (https=)
AT (1) AT381104B (https=)
CA (1) CA1216580A (https=)
DD (1) DD210258A5 (https=)
DK (1) DK221283A (https=)
ES (1) ES8407011A1 (https=)
FI (1) FI831747A7 (https=)
GR (1) GR78850B (https=)
HU (1) HU193528B (https=)
PH (1) PH23417A (https=)
PL (1) PL242097A1 (https=)
PT (1) PT76702B (https=)
RO (1) RO86723B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4977083A (en) * 1988-04-11 1990-12-11 Eli Lilly And Company Processes for preparing A54145 compounds
DE69739532D1 (de) * 1996-03-08 2009-09-24 Astellas Pharma Inc Prozess für die deacylierung von zyklischen lipopeptiden.
CN1425025A (zh) 1999-12-15 2003-06-18 卡比斯特制药公司 作为抗菌剂的新颖的脂肽
MXPA02006028A (es) * 1999-12-15 2004-08-23 Cubist Pharm Inc Lipopeptidos novedosos como agentes antibacterianos.
WO2001044274A1 (en) * 1999-12-15 2001-06-21 Cubist Pharmaceuticals, Inc. Lipopeptides as antibacterial agents
AU2002303480A1 (en) * 2001-04-25 2002-11-05 Wyeth Holdings Corporation Glycopeptide antibiotics
BRPI0923567A2 (pt) * 2008-12-22 2016-09-27 Cubist Pharm Inc agentes antibactericidas novos para o tratamento de infecções gram positivas
US11174288B2 (en) 2016-12-06 2021-11-16 Northeastern University Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3150059A (en) * 1962-12-26 1964-09-22 Lilly Co Eli Penicillin deacylation via actinoplanaceae fermentation
US4050989A (en) * 1974-12-05 1977-09-27 Eisai Co., Ltd. Process of preparing desacyl-pepsidine with bacillus pumilus
US4208403A (en) * 1978-10-16 1980-06-17 Eli Lilly And Company A-21978 Antibiotics and process for their production
US4293485A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of S31794/F-1 nucleus
US4293483A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
US4293488A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912B nucleus
US4293491A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912H nucleus
US4293482A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company A-30912A Nucleus
US4293487A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912D nucleus

Also Published As

Publication number Publication date
GR78850B (https=) 1984-10-02
HU193528B (en) 1987-10-28
US4396543A (en) 1983-08-02
AT381104B (de) 1986-08-25
RO86723A (ro) 1985-04-17
KR840005077A (ko) 1984-11-03
PL242097A1 (en) 1984-07-02
ATA178483A (de) 1986-01-15
FI831747A0 (fi) 1983-05-18
DD210258A5 (de) 1984-06-06
PT76702B (en) 1986-03-27
PT76702A (en) 1983-06-01
DK221283A (da) 1983-11-22
RO86723B (ro) 1985-05-01
ES522559A0 (es) 1984-09-01
FI831747L (fi) 1983-11-22
ES8407011A1 (es) 1984-09-01
FI831747A7 (fi) 1983-11-22
CA1216580A (en) 1987-01-13
DK221283D0 (da) 1983-05-18
PH23417A (en) 1989-08-07

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