DE68925540T2 - Peptid-Antibiotika - Google Patents

Peptid-Antibiotika

Info

Publication number
DE68925540T2
DE68925540T2 DE68925540T DE68925540T DE68925540T2 DE 68925540 T2 DE68925540 T2 DE 68925540T2 DE 68925540 T DE68925540 T DE 68925540T DE 68925540 T DE68925540 T DE 68925540T DE 68925540 T2 DE68925540 T2 DE 68925540T2
Authority
DE
Germany
Prior art keywords
animals
hydrogen
antibiotics
growth
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68925540T
Other languages
English (en)
Other versions
DE68925540D1 (de
Inventor
Laverne Boeck
David Shuichi Fukuda
Marvin Martin Hoehn
Ralph Emil Kastner
Jon Stuart Mynderse
Harold Rudolf Papiska
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/179,773 external-priority patent/US4994270A/en
Priority claimed from US07/179,928 external-priority patent/US5039789A/en
Priority claimed from US07/179,929 external-priority patent/US5028590A/en
Priority claimed from US07/179,930 external-priority patent/US4977083A/en
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE68925540D1 publication Critical patent/DE68925540D1/de
Publication of DE68925540T2 publication Critical patent/DE68925540T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • C12R2001/54Streptomyces fradiae
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE68925540T 1988-04-11 1989-04-11 Peptid-Antibiotika Expired - Fee Related DE68925540T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/179,773 US4994270A (en) 1988-04-11 1988-04-11 A54145 antibiotics and process for their production
US07/179,928 US5039789A (en) 1988-04-11 1988-04-11 A54145 cyclic peptides
US07/179,929 US5028590A (en) 1988-04-11 1988-04-11 Derivatives of A54145 cyclic peptides
US07/179,930 US4977083A (en) 1988-04-11 1988-04-11 Processes for preparing A54145 compounds

Publications (2)

Publication Number Publication Date
DE68925540D1 DE68925540D1 (de) 1996-03-14
DE68925540T2 true DE68925540T2 (de) 1996-06-13

Family

ID=27497367

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68925540T Expired - Fee Related DE68925540T2 (de) 1988-04-11 1989-04-11 Peptid-Antibiotika

Country Status (7)

Country Link
EP (1) EP0337731B1 (de)
JP (1) JPH0213392A (de)
AT (1) ATE133686T1 (de)
CA (1) CA1337758C (de)
DE (1) DE68925540T2 (de)
ES (1) ES2085276T3 (de)
GR (1) GR3019491T3 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19521938C2 (de) * 1995-06-07 1999-11-11 Dirk Vollenbroich Verwendung von cyklischen Lipopeptiden zur Inaktivierung von oder zum Schutz vor Infektionen durch Mikroorganismen der Klasse Mollicutes
US6696412B1 (en) * 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
US20030045678A1 (en) * 2000-12-18 2003-03-06 Dennis Keith Methods for preparing purified lipopeptides
US7235651B2 (en) 2001-12-26 2007-06-26 Cubist Pharmaceuticals, Inc. Genes and proteins involved in the biosynthesis of lipopeptides
JP2005514067A (ja) * 2001-12-26 2005-05-19 エコピア バイオサイエンシーズ インク リポペプチドを見出すための組成物、方法及びシステム
NO20045442L (no) * 2004-05-28 2005-11-29 Gunnar Hagelin Cykliske peptidiske antibiotika

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL68700A0 (en) * 1982-05-21 1983-09-30 Lilly Co Eli Improvements relating to a-21978c cyclic peptide derivatives and their production

Also Published As

Publication number Publication date
EP0337731A3 (de) 1991-07-17
EP0337731B1 (de) 1996-01-31
ES2085276T3 (es) 1996-06-01
EP0337731A2 (de) 1989-10-18
GR3019491T3 (en) 1996-07-31
ATE133686T1 (de) 1996-02-15
CA1337758C (en) 1995-12-19
DE68925540D1 (de) 1996-03-14
JPH0213392A (ja) 1990-01-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee