DD202714A5 - Verfahren zur herstellung 3-substituierter indolylacrylsaeurederivate - Google Patents
Verfahren zur herstellung 3-substituierter indolylacrylsaeurederivate Download PDFInfo
- Publication number
- DD202714A5 DD202714A5 DD82241446A DD24144682A DD202714A5 DD 202714 A5 DD202714 A5 DD 202714A5 DD 82241446 A DD82241446 A DD 82241446A DD 24144682 A DD24144682 A DD 24144682A DD 202714 A5 DD202714 A5 DD 202714A5
- Authority
- DD
- German Democratic Republic
- Prior art keywords
- formula
- compound
- deep
- compounds
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8120878 | 1981-07-07 | ||
| GB8213864 | 1982-05-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD202714A5 true DD202714A5 (de) | 1983-09-28 |
Family
ID=26280039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD82241446A DD202714A5 (de) | 1981-07-07 | 1982-07-06 | Verfahren zur herstellung 3-substituierter indolylacrylsaeurederivate |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4451472A (da) |
| EP (1) | EP0069513B1 (da) |
| AR (1) | AR230056A1 (da) |
| AU (1) | AU532640B2 (da) |
| CS (1) | CS229934B2 (da) |
| DD (1) | DD202714A5 (da) |
| DE (1) | DE3275545D1 (da) |
| DK (1) | DK297382A (da) |
| ES (1) | ES513765A0 (da) |
| FI (1) | FI822386L (da) |
| GB (1) | GB2101992A (da) |
| GR (1) | GR76214B (da) |
| IL (1) | IL66223A0 (da) |
| NO (1) | NO822360L (da) |
| PL (1) | PL240814A1 (da) |
| PT (1) | PT75191B (da) |
| YU (1) | YU145482A (da) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4536505A (en) * | 1983-05-17 | 1985-08-20 | Ciba-Geigy Corporation | Certain N-(pyridyl) indoles |
| US4609733A (en) * | 1984-12-27 | 1986-09-02 | Ciba-Geigy Corporation | 3-keto-substituted-N-pyridylindoles |
| EP0427860A1 (en) * | 1989-03-31 | 1991-05-22 | Kyoto Pharmaceutical Industries, Ltd. | New imidazole derivatives, production thereof, and uses thereof as medicines |
| JPH03258779A (ja) * | 1990-03-06 | 1991-11-19 | Mitsui Toatsu Chem Inc | イミダゾール誘導体及び該イミダゾール誘導体を有効成分とする抗痙攣剤 |
| US5538973A (en) * | 1992-03-27 | 1996-07-23 | Kyoto Pharmaceutical Industries, Ltd. | Imidazole derivative, pharmaceutical use thereof, and intermediate therefor |
| GB9310635D0 (en) * | 1993-05-21 | 1993-07-07 | Glaxo Group Ltd | Chemical compounds |
| GB9319100D0 (en) * | 1993-09-15 | 1993-11-03 | Pfizer Ltd | 3-(3-pyridinyl)h-indoles |
| KR102022716B1 (ko) | 2011-07-29 | 2019-09-18 | 카리오팜 쎄라퓨틱스, 인코포레이티드 | 하이드라지드 함유 핵 수송 조절인자 및 이의 용도 |
| SI3404027T1 (sl) | 2012-05-09 | 2020-08-31 | Biogen Ma Inc. | Modulatorji jedrnega transporta in njihova uporaba |
| WO2014144772A1 (en) | 2013-03-15 | 2014-09-18 | Karyopharm Therapeutics Inc. | Methods of promoting wound healing using crm1 inhibitors |
| DK3492455T3 (da) | 2013-06-21 | 2023-08-14 | Karyopharm Therapeutics Inc | 1,2,4-triazoler som nukleare transportmodulatorer og anvendelse til behandling af specifikke former for cancer |
| SG10201808624VA (en) | 2014-08-15 | 2018-11-29 | Karyopharm Therapeutics Inc | Polymorphs of selinexor |
| WO2017117535A1 (en) | 2015-12-31 | 2017-07-06 | Karyopharm Therapeutics Inc. | Nuclear transport modulators and uses thereof |
| EP3397633A1 (en) | 2015-12-31 | 2018-11-07 | Karyopharm Therapeutics, Inc. | Nuclear transport modulators and uses thereof |
| US11602530B2 (en) | 2016-11-28 | 2023-03-14 | Biogen Ma Inc. | CRM1 inhibitors for treating epilepsy |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3462440A (en) * | 1965-12-03 | 1969-08-19 | American Home Prod | 1,4-bis(2-indol-3-ylethyl)piperidines |
| FR2272081A1 (en) * | 1974-05-22 | 1975-12-19 | Labaz | Anti-inflammatory indolylpyridylketones prepn. - from 2-alkyl (or aryl) indole and pyridine carboxylic acid chlorides |
| DE2960547D1 (en) * | 1978-02-24 | 1981-11-05 | Pfizer Ltd | 3-(imidazol-1-ylalkyl)indoles as selective inhibitors of thromboxane synthetase,pharmaceutical compositions thereof, and methods for preparing them |
| IT1162310B (it) * | 1978-05-02 | 1987-03-25 | Ono Pharmaceutical Co | Derivati di imidazolo e procedimento per produrli |
| JPS55313A (en) * | 1978-06-13 | 1980-01-05 | Kissei Pharmaceut Co Ltd | Imidazole derivative |
| JPS5951943B2 (ja) * | 1978-08-21 | 1984-12-17 | キツセイ薬品工業株式会社 | 新規なイミダゾ−ル誘導体 |
| GB2045244B (en) * | 1979-03-07 | 1983-01-26 | Pfizer Ltd | 3-1-(imidazolylalkyl) indoles |
| US4363912A (en) * | 1980-12-15 | 1982-12-14 | Pfizer Inc. | Indole thromboxane synthetase inhibitors |
-
1982
- 1982-06-23 CS CS825037A patent/CS229934B2/cs unknown
- 1982-06-25 DE DE8282303313T patent/DE3275545D1/de not_active Expired
- 1982-06-25 EP EP82303313A patent/EP0069513B1/en not_active Expired
- 1982-06-25 GB GB08218431A patent/GB2101992A/en not_active Withdrawn
- 1982-07-01 PL PL24081482A patent/PL240814A1/xx unknown
- 1982-07-02 AR AR289873A patent/AR230056A1/es active
- 1982-07-02 US US06/394,554 patent/US4451472A/en not_active Expired - Fee Related
- 1982-07-02 DK DK297382A patent/DK297382A/da unknown
- 1982-07-05 FI FI822386A patent/FI822386L/fi not_active Application Discontinuation
- 1982-07-05 IL IL66223A patent/IL66223A0/xx unknown
- 1982-07-05 GR GR68642A patent/GR76214B/el unknown
- 1982-07-05 YU YU01454/82A patent/YU145482A/xx unknown
- 1982-07-06 AU AU85638/82A patent/AU532640B2/en not_active Ceased
- 1982-07-06 DD DD82241446A patent/DD202714A5/de unknown
- 1982-07-06 PT PT75191A patent/PT75191B/pt unknown
- 1982-07-06 NO NO822360A patent/NO822360L/no unknown
- 1982-07-06 ES ES513765A patent/ES513765A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| AR230056A1 (es) | 1984-02-29 |
| PL240814A1 (en) | 1983-10-10 |
| NO822360L (no) | 1983-01-10 |
| GB2101992A (en) | 1983-01-26 |
| EP0069513A2 (en) | 1983-01-12 |
| CS229934B2 (en) | 1984-07-16 |
| ES8305355A1 (es) | 1983-04-01 |
| YU145482A (en) | 1985-03-20 |
| ES513765A0 (es) | 1983-04-01 |
| DK297382A (da) | 1983-01-08 |
| FI822386A0 (fi) | 1982-07-05 |
| DE3275545D1 (en) | 1987-04-09 |
| FI822386L (fi) | 1983-01-08 |
| EP0069513B1 (en) | 1987-03-04 |
| AU532640B2 (en) | 1983-10-06 |
| AU8563882A (en) | 1983-02-03 |
| EP0069513A3 (en) | 1984-03-21 |
| PT75191A (en) | 1982-08-01 |
| IL66223A0 (en) | 1982-11-30 |
| US4451472A (en) | 1984-05-29 |
| GR76214B (da) | 1984-08-04 |
| PT75191B (en) | 1985-10-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3008632C2 (da) | ||
| DD215546A5 (de) | Verfahren zur herstellung bicyclischer thromboxansynthetase-inhibitoren | |
| CH646154A5 (de) | Imidazol-derivate, verfahren zu ihrer herstellung und solche derivate enthaltende arzneimittel. | |
| CH644597A5 (de) | Imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. | |
| EP1198453B9 (de) | N-(indolcarbonyl-)piperazinderivate als 5-ht2a-rezeptor liganden | |
| DD202290A5 (de) | Verfahren zur herstellung von indolderivaten | |
| DD202714A5 (de) | Verfahren zur herstellung 3-substituierter indolylacrylsaeurederivate | |
| DD264919A5 (de) | Verfahren zur herstellung von 5-hydroxy-3-aminochromanen | |
| CH646426A5 (en) | Process for the preparation of hydantoin derivatives | |
| EP0007399B1 (de) | Indolalkylamine, diese enthaltende pharmazeutische Zubereitungen und Verfahren zu ihrer Herstellung | |
| US4230714A (en) | Imidazole therapeutic agents | |
| EP0095640A1 (de) | Alkylenverbrückte Guanidinothiazolderivate, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel | |
| DD229402A5 (de) | Verfahren zur herstellung von piperidinion-derivaten, die als myocard-schutz eine antiarrhytmische aktivitaet ausweisen | |
| DE3326164A1 (de) | Neue p-oxibenzoesaeure-derivate, sowie verfahren zu ihrer herstellung und ihre verwendung als arzneimittel | |
| EP1228041A2 (de) | Indolderivate und deren verwendung als 5ht2a liganden | |
| CH642348A5 (de) | Alkylthiophenoxyalkylamine. | |
| CH622516A5 (en) | Process for the preparation of substituted indoles, and their use | |
| EP0194579A2 (de) | Neue 3-Pyridylmethylnaphthylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel | |
| EP0401798B1 (de) | Substituierte Aminoalkylbenzolderivate | |
| DD209194A5 (de) | Verfahren zur herstellung von als histamin h tief 2-rezeptor-antagonisten wirkenden pyrimidon-derivaten | |
| DE4204686A1 (de) | Imidazolylphenolderivate, diese enthaltende arzneimittel sowie ein verfahren zur herstellung dieser verbindungen und arzneimitteln | |
| DE2522218B2 (de) | Zusammensetzung für die Human- oder Veterinärmedizin, Methylaminderivate und Verfahren zu deren Herstellung | |
| EP0388739A1 (de) | Tetrahydronaphtalinderivate | |
| DE2656227C2 (de) | Basisch alkylierte Diphenyldisulfid-2,2'-biscarbonsäureamide, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel | |
| AT295516B (de) | Verfahren zur Herstellung neuer cyclischer Amidine und ihrer Salze |