AR230056A1 - Procedimiento para la preparacion de derivados del acido 3-ridilmetilo 3-piridilmetilo 3-inidazolilmetil indolil-acrilico - Google Patents

Procedimiento para la preparacion de derivados del acido 3-ridilmetilo 3-piridilmetilo 3-inidazolilmetil indolil-acrilico

Info

Publication number
AR230056A1
AR230056A1 AR289873A AR28987382A AR230056A1 AR 230056 A1 AR230056 A1 AR 230056A1 AR 289873 A AR289873 A AR 289873A AR 28987382 A AR28987382 A AR 28987382A AR 230056 A1 AR230056 A1 AR 230056A1
Authority
AR
Argentina
Prior art keywords
ridilmetilo
piridilmetilo
inidazolilmetil
acrilico
indolil
Prior art date
Application number
AR289873A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of AR230056A1 publication Critical patent/AR230056A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AR289873A 1981-07-07 1982-07-02 Procedimiento para la preparacion de derivados del acido 3-ridilmetilo 3-piridilmetilo 3-inidazolilmetil indolil-acrilico AR230056A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8120878 1981-07-07
GB8213864 1982-05-13

Publications (1)

Publication Number Publication Date
AR230056A1 true AR230056A1 (es) 1984-02-29

Family

ID=26280039

Family Applications (1)

Application Number Title Priority Date Filing Date
AR289873A AR230056A1 (es) 1981-07-07 1982-07-02 Procedimiento para la preparacion de derivados del acido 3-ridilmetilo 3-piridilmetilo 3-inidazolilmetil indolil-acrilico

Country Status (17)

Country Link
US (1) US4451472A (es)
EP (1) EP0069513B1 (es)
AR (1) AR230056A1 (es)
AU (1) AU532640B2 (es)
CS (1) CS229934B2 (es)
DD (1) DD202714A5 (es)
DE (1) DE3275545D1 (es)
DK (1) DK297382A (es)
ES (1) ES513765A0 (es)
FI (1) FI822386L (es)
GB (1) GB2101992A (es)
GR (1) GR76214B (es)
IL (1) IL66223A0 (es)
NO (1) NO822360L (es)
PL (1) PL240814A1 (es)
PT (1) PT75191B (es)
YU (1) YU145482A (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536505A (en) * 1983-05-17 1985-08-20 Ciba-Geigy Corporation Certain N-(pyridyl) indoles
US4609733A (en) * 1984-12-27 1986-09-02 Ciba-Geigy Corporation 3-keto-substituted-N-pyridylindoles
CA2030557A1 (en) * 1989-03-31 1990-10-01 Hiroshi Matsui Imidazole derivatives, methods for their production and pharmaceutical use thereof
JPH03258779A (ja) * 1990-03-06 1991-11-19 Mitsui Toatsu Chem Inc イミダゾール誘導体及び該イミダゾール誘導体を有効成分とする抗痙攣剤
US5538973A (en) * 1992-03-27 1996-07-23 Kyoto Pharmaceutical Industries, Ltd. Imidazole derivative, pharmaceutical use thereof, and intermediate therefor
GB9310635D0 (en) * 1993-05-21 1993-07-07 Glaxo Group Ltd Chemical compounds
GB9319100D0 (en) * 1993-09-15 1993-11-03 Pfizer Ltd 3-(3-pyridinyl)h-indoles
RS56823B1 (sr) 2011-07-29 2018-04-30 Karyopharm Therapeutics Inc Modulatori nukleusnog transporta koji sadrže hidrazid i njihove upotrebe
US9096543B2 (en) 2012-05-09 2015-08-04 Karyopharm Therapeutics Inc. Nuclear transport modulators and uses thereof
EP2968278B8 (en) 2013-03-15 2019-05-22 Karyopharm Therapeutics Inc. Methods of promoting wound healing using crm1 inhibitors
US9738624B2 (en) 2013-06-21 2017-08-22 Karyopharm Therapeutics Inc. Nuclear transport modulators and uses thereof
EA201790384A1 (ru) 2014-08-15 2017-08-31 Кариофарм Терапевтикс, Инк. Полиморфы селинексора
MA43529A (fr) 2015-12-31 2018-11-07 Karyopharm Therapeutics Inc Modulateurs de transport nucléaire et leurs utilisations
EP3397634A1 (en) 2015-12-31 2018-11-07 Karyopharm Therapeutics, Inc. Nuclear transport modulators and uses thereof
US11602530B2 (en) 2016-11-28 2023-03-14 Biogen Ma Inc. CRM1 inhibitors for treating epilepsy

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3471499A (en) * 1965-12-03 1969-10-07 American Home Prod 1,4-bis-(2-indol-3-yl-ethyl)piperazines
FR2272081A1 (en) * 1974-05-22 1975-12-19 Labaz Anti-inflammatory indolylpyridylketones prepn. - from 2-alkyl (or aryl) indole and pyridine carboxylic acid chlorides
EP0003901B1 (en) * 1978-02-24 1981-08-05 Pfizer Limited 3-(imidazol-1-ylalkyl)indoles as selective inhibitors of thromboxane synthetase,pharmaceutical compositions thereof, and methods for preparing them
IT1162310B (it) * 1978-05-02 1987-03-25 Ono Pharmaceutical Co Derivati di imidazolo e procedimento per produrli
JPS55313A (en) * 1978-06-13 1980-01-05 Kissei Pharmaceut Co Ltd Imidazole derivative
JPS5951943B2 (ja) * 1978-08-21 1984-12-17 キツセイ薬品工業株式会社 新規なイミダゾ−ル誘導体
GB2045244B (en) * 1979-03-07 1983-01-26 Pfizer Ltd 3-1-(imidazolylalkyl) indoles
US4363912A (en) * 1980-12-15 1982-12-14 Pfizer Inc. Indole thromboxane synthetase inhibitors

Also Published As

Publication number Publication date
AU532640B2 (en) 1983-10-06
GB2101992A (en) 1983-01-26
IL66223A0 (en) 1982-11-30
US4451472A (en) 1984-05-29
PT75191A (en) 1982-08-01
EP0069513A2 (en) 1983-01-12
PT75191B (en) 1985-10-04
CS229934B2 (en) 1984-07-16
PL240814A1 (en) 1983-10-10
AU8563882A (en) 1983-02-03
DK297382A (da) 1983-01-08
DE3275545D1 (en) 1987-04-09
GR76214B (es) 1984-08-04
FI822386L (fi) 1983-01-08
FI822386A0 (fi) 1982-07-05
YU145482A (en) 1985-03-20
DD202714A5 (de) 1983-09-28
EP0069513A3 (en) 1984-03-21
NO822360L (no) 1983-01-10
ES8305355A1 (es) 1983-04-01
ES513765A0 (es) 1983-04-01
EP0069513B1 (en) 1987-03-04

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