FI822386A0 - Indol-tromboxansyntetas-inhibitorer, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska kompositioner - Google Patents

Indol-tromboxansyntetas-inhibitorer, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska kompositioner

Info

Publication number
FI822386A0
FI822386A0 FI822386A FI822386A FI822386A0 FI 822386 A0 FI822386 A0 FI 822386A0 FI 822386 A FI822386 A FI 822386A FI 822386 A FI822386 A FI 822386A FI 822386 A0 FI822386 A0 FI 822386A0
Authority
FI
Finland
Prior art keywords
trombox
indo
pharmaceutical composition
foerfarande foer
synthetic inhibitor
Prior art date
Application number
FI822386A
Other languages
English (en)
Other versions
FI822386L (fi
Inventor
Peter Edward Cross
Roger Peter Dickinson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI822386A0 publication Critical patent/FI822386A0/fi
Publication of FI822386L publication Critical patent/FI822386L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI822386A 1981-07-07 1982-07-05 Indol-tromboxansyntetas-inhibitorer, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska kompositioner FI822386L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8120878 1981-07-07
GB8213864 1982-05-13

Publications (2)

Publication Number Publication Date
FI822386A0 true FI822386A0 (fi) 1982-07-05
FI822386L FI822386L (fi) 1983-01-08

Family

ID=26280039

Family Applications (1)

Application Number Title Priority Date Filing Date
FI822386A FI822386L (fi) 1981-07-07 1982-07-05 Indol-tromboxansyntetas-inhibitorer, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska kompositioner

Country Status (17)

Country Link
US (1) US4451472A (fi)
EP (1) EP0069513B1 (fi)
AR (1) AR230056A1 (fi)
AU (1) AU532640B2 (fi)
CS (1) CS229934B2 (fi)
DD (1) DD202714A5 (fi)
DE (1) DE3275545D1 (fi)
DK (1) DK297382A (fi)
ES (1) ES8305355A1 (fi)
FI (1) FI822386L (fi)
GB (1) GB2101992A (fi)
GR (1) GR76214B (fi)
IL (1) IL66223A0 (fi)
NO (1) NO822360L (fi)
PL (1) PL240814A1 (fi)
PT (1) PT75191B (fi)
YU (1) YU145482A (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536505A (en) * 1983-05-17 1985-08-20 Ciba-Geigy Corporation Certain N-(pyridyl) indoles
US4609733A (en) * 1984-12-27 1986-09-02 Ciba-Geigy Corporation 3-keto-substituted-N-pyridylindoles
EP0427860A1 (en) * 1989-03-31 1991-05-22 Kyoto Pharmaceutical Industries, Ltd. New imidazole derivatives, production thereof, and uses thereof as medicines
JPH03258779A (ja) * 1990-03-06 1991-11-19 Mitsui Toatsu Chem Inc イミダゾール誘導体及び該イミダゾール誘導体を有効成分とする抗痙攣剤
US5538973A (en) * 1992-03-27 1996-07-23 Kyoto Pharmaceutical Industries, Ltd. Imidazole derivative, pharmaceutical use thereof, and intermediate therefor
GB9310635D0 (en) * 1993-05-21 1993-07-07 Glaxo Group Ltd Chemical compounds
GB9319100D0 (en) * 1993-09-15 1993-11-03 Pfizer Ltd 3-(3-pyridinyl)h-indoles
PL3333164T3 (pl) 2011-07-29 2023-12-18 Karyopharm Therapeutics Inc. Modulatory transportu jądrowego zawierające ugrupowanie hydrazydu i ich zastosowania
US9266843B2 (en) 2012-05-09 2016-02-23 Karyopharm Therapeutics Inc. Nuclear transport modulators and uses thereof
WO2014144772A1 (en) 2013-03-15 2014-09-18 Karyopharm Therapeutics Inc. Methods of promoting wound healing using crm1 inhibitors
CN105339358B (zh) 2013-06-21 2019-06-04 卡尔约药物治疗公司 核转运调节剂及其用途
ES2926377T3 (es) 2014-08-15 2022-10-25 Karyopharm Therapeutics Inc Polimorfos de selinexor
MA43530A (fr) 2015-12-31 2018-11-07 Karyopharm Therapeutics Inc Modulateurs de transport nucléaire et leurs utilisations
US10526295B2 (en) 2015-12-31 2020-01-07 Karyopharm Therapeutics Inc. Nuclear transport modulators and uses thereof
US11602530B2 (en) 2016-11-28 2023-03-14 Biogen Ma Inc. CRM1 inhibitors for treating epilepsy

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3445472A (en) * 1965-12-03 1969-05-20 American Home Prod Mono- and di-aroyl pyridylethyl and piperidylethyl indoles
FR2272081A1 (en) * 1974-05-22 1975-12-19 Labaz Anti-inflammatory indolylpyridylketones prepn. - from 2-alkyl (or aryl) indole and pyridine carboxylic acid chlorides
EP0003901B1 (en) * 1978-02-24 1981-08-05 Pfizer Limited 3-(imidazol-1-ylalkyl)indoles as selective inhibitors of thromboxane synthetase,pharmaceutical compositions thereof, and methods for preparing them
IT1162310B (it) * 1978-05-02 1987-03-25 Ono Pharmaceutical Co Derivati di imidazolo e procedimento per produrli
JPS55313A (en) * 1978-06-13 1980-01-05 Kissei Pharmaceut Co Ltd Imidazole derivative
JPS5951943B2 (ja) * 1978-08-21 1984-12-17 キツセイ薬品工業株式会社 新規なイミダゾ−ル誘導体
GB2045244B (en) * 1979-03-07 1983-01-26 Pfizer Ltd 3-1-(imidazolylalkyl) indoles
US4363912A (en) * 1980-12-15 1982-12-14 Pfizer Inc. Indole thromboxane synthetase inhibitors

Also Published As

Publication number Publication date
FI822386L (fi) 1983-01-08
EP0069513A2 (en) 1983-01-12
ES513765A0 (es) 1983-04-01
CS229934B2 (en) 1984-07-16
YU145482A (en) 1985-03-20
GB2101992A (en) 1983-01-26
ES8305355A1 (es) 1983-04-01
GR76214B (fi) 1984-08-04
AR230056A1 (es) 1984-02-29
NO822360L (no) 1983-01-10
US4451472A (en) 1984-05-29
DK297382A (da) 1983-01-08
AU532640B2 (en) 1983-10-06
EP0069513B1 (en) 1987-03-04
IL66223A0 (en) 1982-11-30
PT75191A (en) 1982-08-01
AU8563882A (en) 1983-02-03
DD202714A5 (de) 1983-09-28
EP0069513A3 (en) 1984-03-21
PT75191B (en) 1985-10-04
DE3275545D1 (en) 1987-04-09
PL240814A1 (en) 1983-10-10

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: PFIZER CORPORATION