GR76214B - - Google Patents

Info

Publication number
GR76214B
GR76214B GR68642A GR820168642A GR76214B GR 76214 B GR76214 B GR 76214B GR 68642 A GR68642 A GR 68642A GR 820168642 A GR820168642 A GR 820168642A GR 76214 B GR76214 B GR 76214B
Authority
GR
Greece
Application number
GR68642A
Inventor
Peter Edward Cross
Roger Peter Dickinson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of GR76214B publication Critical patent/GR76214B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GR68642A 1981-07-07 1982-07-05 GR76214B (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8120878 1981-07-07
GB8213864 1982-05-13

Publications (1)

Publication Number Publication Date
GR76214B true GR76214B (el) 1984-08-04

Family

ID=26280039

Family Applications (1)

Application Number Title Priority Date Filing Date
GR68642A GR76214B (el) 1981-07-07 1982-07-05

Country Status (17)

Country Link
US (1) US4451472A (el)
EP (1) EP0069513B1 (el)
AR (1) AR230056A1 (el)
AU (1) AU532640B2 (el)
CS (1) CS229934B2 (el)
DD (1) DD202714A5 (el)
DE (1) DE3275545D1 (el)
DK (1) DK297382A (el)
ES (1) ES513765A0 (el)
FI (1) FI822386L (el)
GB (1) GB2101992A (el)
GR (1) GR76214B (el)
IL (1) IL66223A0 (el)
NO (1) NO822360L (el)
PL (1) PL240814A1 (el)
PT (1) PT75191B (el)
YU (1) YU145482A (el)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536505A (en) * 1983-05-17 1985-08-20 Ciba-Geigy Corporation Certain N-(pyridyl) indoles
US4609733A (en) * 1984-12-27 1986-09-02 Ciba-Geigy Corporation 3-keto-substituted-N-pyridylindoles
CA2030557A1 (en) * 1989-03-31 1990-10-01 Hiroshi Matsui Imidazole derivatives, methods for their production and pharmaceutical use thereof
JPH03258779A (ja) * 1990-03-06 1991-11-19 Mitsui Toatsu Chem Inc イミダゾール誘導体及び該イミダゾール誘導体を有効成分とする抗痙攣剤
US5538973A (en) * 1992-03-27 1996-07-23 Kyoto Pharmaceutical Industries, Ltd. Imidazole derivative, pharmaceutical use thereof, and intermediate therefor
GB9310635D0 (en) * 1993-05-21 1993-07-07 Glaxo Group Ltd Chemical compounds
GB9319100D0 (en) * 1993-09-15 1993-11-03 Pfizer Ltd 3-(3-pyridinyl)h-indoles
CN110372673B (zh) 2011-07-29 2023-10-03 卡尔约药物治疗公司 含酰肼的核运输调节剂及其用途
ES2702279T3 (es) 2012-05-09 2019-02-28 Biogen Ma Inc Moduladores del transporte nuclear y usos de los mismos
US10202366B2 (en) 2013-03-15 2019-02-12 Karyopharm Therapeutics Inc. Methods of promoting wound healing using CRM1 inhibitors
ME03421B (me) 2013-06-21 2020-01-20 Karyopharm Therapeutics Inc 1,2,4-triazoli kao modulatori nuklearnog transporta i njihova upotreba
EP4112615A1 (en) 2014-08-15 2023-01-04 Karyopharm Therapeutics Inc. Compositions comprising one crystalline form of selinexor
EP3397634A1 (en) 2015-12-31 2018-11-07 Karyopharm Therapeutics, Inc. Nuclear transport modulators and uses thereof
MA43529A (fr) 2015-12-31 2018-11-07 Karyopharm Therapeutics Inc Modulateurs de transport nucléaire et leurs utilisations
WO2018098472A1 (en) 2016-11-28 2018-05-31 Karyopharm Therapeutics Inc. Crm1 inhibitors for treating epilepsy

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3445472A (en) * 1965-12-03 1969-05-20 American Home Prod Mono- and di-aroyl pyridylethyl and piperidylethyl indoles
FR2272081A1 (en) * 1974-05-22 1975-12-19 Labaz Anti-inflammatory indolylpyridylketones prepn. - from 2-alkyl (or aryl) indole and pyridine carboxylic acid chlorides
DE2960547D1 (en) * 1978-02-24 1981-11-05 Pfizer Ltd 3-(imidazol-1-ylalkyl)indoles as selective inhibitors of thromboxane synthetase,pharmaceutical compositions thereof, and methods for preparing them
IT1162310B (it) * 1978-05-02 1987-03-25 Ono Pharmaceutical Co Derivati di imidazolo e procedimento per produrli
JPS55313A (en) * 1978-06-13 1980-01-05 Kissei Pharmaceut Co Ltd Imidazole derivative
JPS5951943B2 (ja) * 1978-08-21 1984-12-17 キツセイ薬品工業株式会社 新規なイミダゾ−ル誘導体
GB2045244B (en) * 1979-03-07 1983-01-26 Pfizer Ltd 3-1-(imidazolylalkyl) indoles
US4363912A (en) * 1980-12-15 1982-12-14 Pfizer Inc. Indole thromboxane synthetase inhibitors

Also Published As

Publication number Publication date
ES8305355A1 (es) 1983-04-01
EP0069513B1 (en) 1987-03-04
FI822386A0 (fi) 1982-07-05
DD202714A5 (de) 1983-09-28
DE3275545D1 (en) 1987-04-09
YU145482A (en) 1985-03-20
NO822360L (no) 1983-01-10
EP0069513A3 (en) 1984-03-21
AU8563882A (en) 1983-02-03
IL66223A0 (en) 1982-11-30
AU532640B2 (en) 1983-10-06
CS229934B2 (en) 1984-07-16
FI822386L (fi) 1983-01-08
GB2101992A (en) 1983-01-26
DK297382A (da) 1983-01-08
PL240814A1 (en) 1983-10-10
PT75191B (en) 1985-10-04
ES513765A0 (es) 1983-04-01
EP0069513A2 (en) 1983-01-12
AR230056A1 (es) 1984-02-29
US4451472A (en) 1984-05-29
PT75191A (en) 1982-08-01

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