DD202290A5 - Verfahren zur herstellung von indolderivaten - Google Patents

Verfahren zur herstellung von indolderivaten Download PDF

Info

Publication number
DD202290A5
DD202290A5 DD81235742A DD23574281A DD202290A5 DD 202290 A5 DD202290 A5 DD 202290A5 DD 81235742 A DD81235742 A DD 81235742A DD 23574281 A DD23574281 A DD 23574281A DD 202290 A5 DD202290 A5 DD 202290A5
Authority
DD
German Democratic Republic
Prior art keywords
formula
compound
alkyl
deep
converting
Prior art date
Application number
DD81235742A
Other languages
German (de)
English (en)
Inventor
Peter E Cross
Roger P Dickinson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DD202290A5 publication Critical patent/DD202290A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
DD81235742A 1980-12-15 1981-12-14 Verfahren zur herstellung von indolderivaten DD202290A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8040081 1980-12-15

Publications (1)

Publication Number Publication Date
DD202290A5 true DD202290A5 (de) 1983-09-07

Family

ID=10517993

Family Applications (1)

Application Number Title Priority Date Filing Date
DD81235742A DD202290A5 (de) 1980-12-15 1981-12-14 Verfahren zur herstellung von indolderivaten

Country Status (22)

Country Link
US (1) US4363912A (fi)
EP (1) EP0054417B1 (fi)
JP (1) JPS57181082A (fi)
KR (1) KR830007552A (fi)
AR (1) AR229110A1 (fi)
AU (1) AU525296B2 (fi)
CA (1) CA1143737A (fi)
CS (1) CS228527B2 (fi)
DD (1) DD202290A5 (fi)
DE (1) DE3167879D1 (fi)
DK (1) DK552581A (fi)
ES (1) ES8308872A1 (fi)
FI (1) FI814003L (fi)
GR (1) GR76355B (fi)
IE (1) IE51949B1 (fi)
IL (1) IL64534A0 (fi)
NO (1) NO814264L (fi)
PH (1) PH17576A (fi)
PL (1) PL133634B1 (fi)
PT (1) PT74123B (fi)
YU (1) YU293481A (fi)
ZA (1) ZA818665B (fi)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS229934B2 (en) * 1981-07-07 1984-07-16 Pfizer Production method subst.indolylacryte acid derivative
US4460777A (en) * 1981-11-19 1984-07-17 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4478842A (en) * 1981-11-19 1984-10-23 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4511573A (en) * 1983-05-17 1985-04-16 Ciba-Geigy Corporation 3-Substituted-2-(heteroaryl) indoles
US4536505A (en) * 1983-05-17 1985-08-20 Ciba-Geigy Corporation Certain N-(pyridyl) indoles
GB8524157D0 (en) * 1984-10-19 1985-11-06 Ici America Inc Heterocyclic amides
US4609733A (en) * 1984-12-27 1986-09-02 Ciba-Geigy Corporation 3-keto-substituted-N-pyridylindoles
GB8609175D0 (en) * 1986-04-15 1986-05-21 Ici America Inc Heterocyclic carboxamides
OA11622A (en) * 1998-03-31 2004-09-16 Inst For Pharm Discovery Inc Substituted indolealkanoic acids.
TNSN99224A1 (fr) 1998-12-01 2005-11-10 Inst For Pharm Discovery Inc Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
WO2001051489A2 (en) * 2000-01-14 2001-07-19 The Institutes For Pharmaceutical Discovery, Llc Methods for lowering uric acid levels
BR0316583A (pt) * 2002-12-10 2005-10-04 Wyeth Corp Derivados de ácido acético 3-alquil e 3-arilalquil 1h-indol-1-il substituìdo como inibidores do inibidor-1 do ativador do plasminogênio (pai-1)
GB0324763D0 (en) 2003-10-23 2003-11-26 Oxagen Ltd Use of compounds in therapy
RU2458918C2 (ru) 2006-07-22 2012-08-20 Оксаген Лимитед Соединения, обладающие антагонистической активностью по отношению к crth2
CA2700539A1 (en) * 2007-09-24 2009-04-02 Allergan, Inc. Indole compounds bearing aryl or heteroaryl groups having sphingosine-1-phosphate (s1p) receptor biological activity
RU2503672C2 (ru) 2008-01-18 2014-01-10 Оксаген Лимитед Соединения, обладающие активностью антагонистов crth2
US7750027B2 (en) * 2008-01-18 2010-07-06 Oxagen Limited Compounds having CRTH2 antagonist activity
WO2009093029A1 (en) * 2008-01-22 2009-07-30 Oxagen Limited Compounds having crth2 antagonist activity
EP2265581A1 (en) 2008-01-22 2010-12-29 Oxagen Limited Compounds having crth2 antagonist activity
GB201322273D0 (en) 2013-12-17 2014-01-29 Atopix Therapeutics Ltd Process
GB201407807D0 (en) * 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
GB201407820D0 (en) * 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5173M (fi) * 1966-02-11 1967-06-19
FR7337M (fi) * 1968-01-11 1969-10-13
GB2045244B (en) 1979-03-07 1983-01-26 Pfizer Ltd 3-1-(imidazolylalkyl) indoles
US4322533A (en) * 1980-03-17 1982-03-30 Lesher George Y 1H-Indole-2,3-dione derivatives

Also Published As

Publication number Publication date
FI814003L (fi) 1982-06-16
IE812928L (en) 1982-06-15
PL133634B1 (en) 1985-06-29
AR229110A1 (es) 1983-06-15
ES507960A0 (es) 1983-10-01
KR830007552A (ko) 1983-10-21
IL64534A0 (en) 1982-03-31
DE3167879D1 (en) 1985-01-31
YU293481A (en) 1984-10-31
NO814264L (no) 1982-06-16
PH17576A (en) 1984-10-01
GR76355B (fi) 1984-08-06
EP0054417A1 (en) 1982-06-23
EP0054417B1 (en) 1984-12-19
CA1143737A (en) 1983-03-29
AU7848881A (en) 1982-06-24
PT74123B (en) 1983-12-19
ZA818665B (en) 1982-10-27
IE51949B1 (en) 1987-04-29
ES8308872A1 (es) 1983-10-01
US4363912A (en) 1982-12-14
PT74123A (en) 1982-01-01
CS228527B2 (en) 1984-05-14
AU525296B2 (en) 1982-10-28
JPS57181082A (en) 1982-11-08
DK552581A (da) 1982-06-16
PL234253A1 (en) 1983-05-23

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