DD151162A5 - Verfahren zur herstellung von 3-allyl-7,8-dihydroxy-6-halogen-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1h-3-benzazepin-derivaten - Google Patents

Verfahren zur herstellung von 3-allyl-7,8-dihydroxy-6-halogen-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1h-3-benzazepin-derivaten Download PDF

Info

Publication number
DD151162A5
DD151162A5 DD80221356A DD22135680A DD151162A5 DD 151162 A5 DD151162 A5 DD 151162A5 DD 80221356 A DD80221356 A DD 80221356A DD 22135680 A DD22135680 A DD 22135680A DD 151162 A5 DD151162 A5 DD 151162A5
Authority
DD
German Democratic Republic
Prior art keywords
acid
tetrahydro
general formula
compound
allyl
Prior art date
Application number
DD80221356A
Other languages
German (de)
English (en)
Inventor
Joseph Weinstock
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of DD151162A5 publication Critical patent/DD151162A5/de

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Classifications

    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N3/00—Scanning details of television systems; Combination thereof with generation of supply voltages
    • H04N3/10—Scanning details of television systems; Combination thereof with generation of supply voltages by means not exclusively optical-mechanical
    • H04N3/16—Scanning details of television systems; Combination thereof with generation of supply voltages by means not exclusively optical-mechanical by deflecting electron beam in cathode-ray tube, e.g. scanning corrections
    • H04N3/26—Modifications of scanning arrangements to improve focusing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Multimedia (AREA)
  • Signal Processing (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DD80221356A 1979-05-25 1980-05-23 Verfahren zur herstellung von 3-allyl-7,8-dihydroxy-6-halogen-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1h-3-benzazepin-derivaten DD151162A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/042,680 US4251525A (en) 1979-05-25 1979-05-25 3-Allyl-7,8-dihydroxy-6-halo-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine derivatives

Publications (1)

Publication Number Publication Date
DD151162A5 true DD151162A5 (de) 1981-10-08

Family

ID=21923200

Family Applications (1)

Application Number Title Priority Date Filing Date
DD80221356A DD151162A5 (de) 1979-05-25 1980-05-23 Verfahren zur herstellung von 3-allyl-7,8-dihydroxy-6-halogen-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1h-3-benzazepin-derivaten

Country Status (26)

Country Link
US (1) US4251525A (cs)
EP (1) EP0020107B1 (cs)
JP (1) JPS55157569A (cs)
KR (1) KR840001212B1 (cs)
AT (1) ATE1448T1 (cs)
AU (1) AU534783B2 (cs)
CS (1) CS216929B2 (cs)
DD (1) DD151162A5 (cs)
DE (1) DE3060753D1 (cs)
DK (1) DK154833C (cs)
ES (1) ES8104235A1 (cs)
FI (1) FI66599C (cs)
GR (1) GR68523B (cs)
HU (1) HU180582B (cs)
IE (1) IE49815B1 (cs)
IL (1) IL60144A (cs)
IN (1) IN154373B (cs)
MX (1) MX6526E (cs)
NO (1) NO146025C (cs)
NZ (1) NZ193767A (cs)
PH (1) PH15922A (cs)
PL (1) PL124374B1 (cs)
PT (1) PT71262A (cs)
SU (1) SU982539A3 (cs)
YU (1) YU140580A (cs)
ZA (1) ZA802325B (cs)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4340601A (en) * 1980-07-08 1982-07-20 Smithkline Corporation Dopaminergic isoquinolines
US4328153A (en) * 1980-07-17 1982-05-04 Smith Kline Corporation Dopaminergic benzazepines
CA2098446A1 (en) * 1992-09-30 1994-03-31 Eckard Weber 2,5-dihydro-2,5-dioxo-1h-azepines and 2,5-dihydro-2-oxo-1h-azepines and the use thereof as excitatory amino acid and glycine receptor antagonists
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
US20030051728A1 (en) * 2001-06-05 2003-03-20 Lloyd Peter M. Method and device for delivering a physiologically active compound
US7090830B2 (en) * 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US20040105818A1 (en) * 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
US7913688B2 (en) * 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
CA2526475A1 (en) 2003-05-21 2004-12-02 Alexza Pharmaceuticals, Inc. Optically ignited or electrically ignited self-contained heating unit and drug-supply unit employing same
US7540286B2 (en) * 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
US7581540B2 (en) * 2004-08-12 2009-09-01 Alexza Pharmaceuticals, Inc. Aerosol drug delivery device incorporating percussively activated heat packages
US20100006092A1 (en) * 2004-08-12 2010-01-14 Alexza Pharmaceuticals, Inc. Aerosol Drug Delivery Device Incorporating Percussively Activated Heat Packages
EP2121088B1 (en) 2007-03-09 2016-07-13 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
KR102852740B1 (ko) 2018-02-02 2025-08-29 알렉스자 파마스티칼즈, 인크. 전기적 응축 에어로졸 디바이스

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4160765A (en) * 1976-11-17 1979-07-10 Smithkline Corporation Method for 6-bromination of 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
ZA777444B (en) * 1977-01-19 1978-10-25 Smithkline Corp Alkylthio-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines having dopaminergic activity
US4104379A (en) * 1977-01-19 1978-08-01 Smithkline Corporation Substituted 1-alkylthiophenyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
US4108989A (en) * 1977-04-01 1978-08-22 Smithkline Corporation 2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diones
US4171359A (en) * 1978-04-12 1979-10-16 Smithkline Corporation Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines

Also Published As

Publication number Publication date
PH15922A (en) 1983-04-22
EP0020107B1 (en) 1982-08-11
DK154833C (da) 1989-05-16
JPS55157569A (en) 1980-12-08
NO146025C (no) 1982-07-14
IE801063L (en) 1980-11-25
DE3060753D1 (en) 1982-10-07
KR830002715A (ko) 1983-05-30
IN154373B (cs) 1984-10-20
NO801497L (no) 1980-11-26
ES491620A0 (es) 1981-04-16
AU534783B2 (en) 1984-02-16
PL224415A1 (cs) 1981-02-13
NZ193767A (en) 1982-12-21
CS216929B2 (en) 1982-12-31
ATE1448T1 (de) 1982-08-15
ES8104235A1 (es) 1981-04-16
IL60144A0 (en) 1980-07-31
DK154833B (da) 1988-12-27
MX6526E (es) 1985-06-28
US4251525A (en) 1981-02-17
SU982539A3 (ru) 1982-12-15
DK217380A (da) 1980-11-26
FI66599B (fi) 1984-07-31
GR68523B (cs) 1982-01-11
PT71262A (en) 1980-06-01
NO146025B (no) 1982-04-05
KR840001212B1 (ko) 1984-08-21
YU140580A (en) 1983-02-28
IL60144A (en) 1984-09-30
ZA802325B (en) 1981-08-26
EP0020107A1 (en) 1980-12-10
AU5852080A (en) 1980-11-27
IE49815B1 (en) 1985-12-25
HU180582B (en) 1983-03-28
FI801612A7 (fi) 1980-11-26
PL124374B1 (en) 1983-01-31
FI66599C (fi) 1984-11-12

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ENJ Ceased due to non-payment of renewal fee