CZ300925B6 - Kit ze soucástí pro antitrombotickou terapii, antagonista receptoru P2T, farmaceutický prostredek a lécivo pro lécení trombózy - Google Patents

Kit ze soucástí pro antitrombotickou terapii, antagonista receptoru P2T, farmaceutický prostredek a lécivo pro lécení trombózy Download PDF

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Publication number
CZ300925B6
CZ300925B6 CZ20021887A CZ20021887A CZ300925B6 CZ 300925 B6 CZ300925 B6 CZ 300925B6 CZ 20021887 A CZ20021887 A CZ 20021887A CZ 20021887 A CZ20021887 A CZ 20021887A CZ 300925 B6 CZ300925 B6 CZ 300925B6
Authority
CZ
Czechia
Prior art keywords
pharmaceutically acceptable
compound
receptor antagonist
formula
melagatran
Prior art date
Application number
CZ20021887A
Other languages
Czech (cs)
English (en)
Other versions
CZ20021887A3 (cs
Inventor
Dixon@John
Humphries@Robert
Jarvis@Gavin
Kirk@Ian
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of CZ20021887A3 publication Critical patent/CZ20021887A3/cs
Publication of CZ300925B6 publication Critical patent/CZ300925B6/cs

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CZ20021887A 1999-12-01 2000-11-29 Kit ze soucástí pro antitrombotickou terapii, antagonista receptoru P2T, farmaceutický prostredek a lécivo pro lécení trombózy CZ300925B6 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9904377A SE9904377D0 (sv) 1999-12-01 1999-12-01 Pharmaceutical combinations

Publications (2)

Publication Number Publication Date
CZ20021887A3 CZ20021887A3 (cs) 2002-11-13
CZ300925B6 true CZ300925B6 (cs) 2009-09-09

Family

ID=20417947

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ20021887A CZ300925B6 (cs) 1999-12-01 2000-11-29 Kit ze soucástí pro antitrombotickou terapii, antagonista receptoru P2T, farmaceutický prostredek a lécivo pro lécení trombózy

Country Status (33)

Country Link
US (2) US20030032618A1 (fr)
EP (2) EP1719526A3 (fr)
JP (1) JP2003515565A (fr)
KR (1) KR100785953B1 (fr)
CN (1) CN1402639A (fr)
AR (1) AR033658A1 (fr)
AT (1) ATE332698T1 (fr)
AU (1) AU781691B2 (fr)
BR (1) BR0016043A (fr)
CA (1) CA2391161C (fr)
CO (1) CO5271717A1 (fr)
CY (1) CY1105211T1 (fr)
CZ (1) CZ300925B6 (fr)
DE (1) DE60029340T2 (fr)
DK (1) DK1237559T3 (fr)
EE (1) EE05127B1 (fr)
ES (1) ES2267591T3 (fr)
HK (1) HK1047893A1 (fr)
HU (1) HU230890B1 (fr)
IL (1) IL149495A0 (fr)
IS (1) IS2841B (fr)
MX (1) MXPA02004871A (fr)
MY (1) MY128896A (fr)
NO (1) NO331215B1 (fr)
NZ (2) NZ530058A (fr)
PT (1) PT1237559E (fr)
RU (1) RU2242232C2 (fr)
SE (1) SE9904377D0 (fr)
SI (1) SI1237559T1 (fr)
SK (1) SK288707B6 (fr)
TW (1) TWI251491B (fr)
WO (1) WO2001039781A1 (fr)
ZA (1) ZA200203707B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7115585B2 (en) 2000-08-21 2006-10-03 Inspire Pharmaceuticals, Inc. Compositions for treating epithelial and retinal tissue diseases
US7132408B2 (en) 2000-08-21 2006-11-07 Inspire Pharmaceuticals, Inc. Composition and method for inhibiting platelet aggregation
US6897201B2 (en) 2000-08-21 2005-05-24 Inspire Pharmaceuticals, Inc. Compositions and methods for the treatment of glaucoma or ocular hypertension
US7018985B1 (en) 2000-08-21 2006-03-28 Inspire Pharmaceuticals, Inc. Composition and method for inhibiting platelet aggregation
US7452870B2 (en) 2000-08-21 2008-11-18 Inspire Pharmaceuticals, Inc. Drug-eluting stents coated with P2Y12 receptor antagonist compound
DE10064797A1 (de) * 2000-12-22 2002-06-27 Knoll Ag Orale und parenterale pharmazeutische Formulierung, umfassend eine niedermolekulare Thrombininhibitor-Pro-Pharmakon
SE0101932D0 (sv) * 2001-05-31 2001-05-31 Astrazeneca Ab Pharmaceutical combinations
US7435724B2 (en) 2002-02-27 2008-10-14 Inspire Pharmaceutical, Inc. Degradation-resistant mononucleoside phosphate compounds
EP1604669A1 (fr) * 2004-06-10 2005-12-14 Institut National De La Sante Et De La Recherche Medicale (Inserm) Utilisation d'analogues de l'ATP pour le traitement de maladies cardiovasculaires
EP1926736A4 (fr) * 2005-09-21 2010-08-25 Chong Kun Dang Pharm Corp Nouveau complexe de resinate de s-clopidogrel et procede pour le produire
US20120141468A1 (en) 2008-05-13 2012-06-07 Lisa Ruderman Chen Maintenance of platelet inhibition during antiplatelet therapy
US20130303477A1 (en) 2008-05-13 2013-11-14 The Medicines Company Maintenance of Platelet Inhibition During Antiplatelet Therapy
US9427448B2 (en) 2009-11-11 2016-08-30 The Medicines Company Methods of treating, reducing the incidence of, and/or preventing ischemic events
US8759316B2 (en) 2008-05-13 2014-06-24 The Medicines Company Maintenance of platelet inhibition during antiplatelet therapy
WO2009140092A1 (fr) 2008-05-13 2009-11-19 The Medicines Company Conservation de l'inhibition de plaquettes durant une thérapie anti-plaquettes
US10376532B2 (en) 2009-11-11 2019-08-13 Chiesi Farmaceutici, S.P.A. Methods of treating, reducing the incidence of, and/or preventing ischemic events
EA028885B1 (ru) * 2009-11-11 2018-01-31 Чиези Фармачеутичи С.П.А. Способы лечения или предотвращения тромбоза стента и инфаркта миокарда (варианты)
WO2012109406A1 (fr) 2011-02-09 2012-08-16 The Medicines Company Méthodes de traitement de l'hypertension pulmonaire
CN106102750A (zh) 2013-03-09 2016-11-09 凯西制药公司 治疗局部缺血事件、减少局部缺血事件的发生和/或预防局部缺血事件的方法
WO2018234565A1 (fr) 2017-06-23 2018-12-27 Chiesi Farmaceutici S.P.A. Procédé de prévention de thrombose de shunt de l'artère systémique-pulmonaire

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992017488A1 (fr) * 1991-04-06 1992-10-15 Fisons Plc Analogues d'atp
WO1994018216A1 (fr) * 1993-02-10 1994-08-18 Astra Pharmaceuticals Limited Analogues d'adenosine triphosphate (atb) substitues en position 2 par n-alkyle
US5795896A (en) * 1994-12-02 1998-08-18 Astra Aktiebolag Antithrombotic formulation, process for its manufacturing, and use thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8826448D0 (en) * 1988-11-11 1988-12-14 Thrombosis Res Inst Improvements in/relating to organic compounds
MA23420A1 (fr) * 1994-01-07 1995-10-01 Smithkline Beecham Corp Antagonistes bicycliques de fibrinogene.
US5747496A (en) * 1995-07-11 1998-05-05 Astra Pharmaceuticals Limited Inhibitors of platelet aggregation
PT1087775E (pt) * 1998-06-17 2005-11-30 Bristol Myers Squibb Co Prevencao de enfarte cerebral por administracao de uma combinacao de farmacos antiplaquetarios bloqueadores de receptores de adp e anti-hipertensivos
SE9802973D0 (sv) * 1998-09-03 1998-09-03 Astra Ab Immediate release tablet
TWI229674B (en) * 1998-12-04 2005-03-21 Astra Pharma Prod Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses
US6462021B1 (en) * 2000-11-06 2002-10-08 Astrazeneca Ab Use of low molecular weight thrombin inhibitor
US6696468B2 (en) * 2002-05-16 2004-02-24 Dainippon Pharmaceutical Co., Ltd. (s)-4-amino-5-chloro-2-methoxy-n-[1-[1-(2-tetrahydrofuryl-carbonyl)-4-piperidinylmethyl]-4-piperidinyl]benzamide, process for the preparation thereof, pharmaceutical composition containing the same, and intermediate therefor
US20040067995A1 (en) * 2002-10-02 2004-04-08 Wong Pancras C. Novel combination of a factor Xa inhibitor and clopidogrel
JPWO2005007191A1 (ja) * 2003-07-16 2006-08-31 協和醗酵工業株式会社 医薬組成物

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992017488A1 (fr) * 1991-04-06 1992-10-15 Fisons Plc Analogues d'atp
WO1994018216A1 (fr) * 1993-02-10 1994-08-18 Astra Pharmaceuticals Limited Analogues d'adenosine triphosphate (atb) substitues en position 2 par n-alkyle
US5795896A (en) * 1994-12-02 1998-08-18 Astra Aktiebolag Antithrombotic formulation, process for its manufacturing, and use thereof

Also Published As

Publication number Publication date
SI1237559T1 (sl) 2007-02-28
US20060270607A1 (en) 2006-11-30
DE60029340D1 (de) 2006-08-24
EE200200271A (et) 2003-06-16
NO20022606L (no) 2002-07-11
IS2841B (is) 2013-08-15
HUP0203585A2 (hu) 2003-03-28
EP1719526A2 (fr) 2006-11-08
HK1047893A1 (en) 2003-03-14
NO20022606D0 (no) 2002-05-31
AU781691B2 (en) 2005-06-09
EP1719526A3 (fr) 2007-04-25
AR033658A1 (es) 2004-01-07
SK288707B6 (sk) 2019-10-02
IS6398A (is) 2002-05-27
WO2001039781A1 (fr) 2001-06-07
NO331215B1 (no) 2011-11-07
US20030032618A1 (en) 2003-02-13
EE05127B1 (et) 2009-02-16
SE9904377D0 (sv) 1999-12-01
NZ530058A (en) 2005-04-29
BR0016043A (pt) 2002-07-23
CO5271717A1 (es) 2003-04-30
EP1237559A1 (fr) 2002-09-11
JP2003515565A (ja) 2003-05-07
CY1105211T1 (el) 2010-03-03
MXPA02004871A (es) 2002-08-30
IL149495A0 (en) 2004-03-28
CA2391161C (fr) 2010-10-05
PT1237559E (pt) 2006-10-31
DK1237559T3 (da) 2006-10-30
KR20020069201A (ko) 2002-08-29
NZ518904A (en) 2004-02-27
RU2242232C2 (ru) 2004-12-20
EP1237559B1 (fr) 2006-07-12
RU2002117296A (ru) 2004-01-20
CZ20021887A3 (cs) 2002-11-13
MY128896A (en) 2007-02-28
ZA200203707B (en) 2003-10-29
SK7502002A3 (en) 2003-02-04
CA2391161A1 (fr) 2001-06-07
HUP0203585A3 (en) 2005-01-28
AU1910901A (en) 2001-06-12
KR100785953B1 (ko) 2007-12-14
TWI251491B (en) 2006-03-21
CN1402639A (zh) 2003-03-12
DE60029340T2 (de) 2007-07-19
ATE332698T1 (de) 2006-08-15
PL355841A1 (en) 2004-05-17
ES2267591T3 (es) 2007-03-16
HU230890B1 (hu) 2018-12-28

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MK4A Patent expired

Effective date: 20201129