CZ298148B6 - Zarízení na jedno pouzití pro axenické pestování a sklízení bunek a/nebo tkání, baterie takových zarízení a príslusný zpusob - Google Patents

Zarízení na jedno pouzití pro axenické pestování a sklízení bunek a/nebo tkání, baterie takových zarízení a príslusný zpusob Download PDF

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Publication number
CZ298148B6
CZ298148B6 CZ0104799A CZ104799A CZ298148B6 CZ 298148 B6 CZ298148 B6 CZ 298148B6 CZ 0104799 A CZ0104799 A CZ 0104799A CZ 104799 A CZ104799 A CZ 104799A CZ 298148 B6 CZ298148 B6 CZ 298148B6
Authority
CZ
Czechia
Prior art keywords
harvesting
container
tissues
sterile
cells
Prior art date
Application number
CZ0104799A
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Czech (cs)
English (en)
Other versions
CZ104799A3 (cs
Inventor
Shaaltiel@Yoseph
Original Assignee
Protalix Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Protalix Ltd. filed Critical Protalix Ltd.
Publication of CZ104799A3 publication Critical patent/CZ104799A3/cs
Publication of CZ298148B6 publication Critical patent/CZ298148B6/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/14—Bags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/22—Transparent or translucent parts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
CZ0104799A 1996-09-26 1997-09-26 Zarízení na jedno pouzití pro axenické pestování a sklízení bunek a/nebo tkání, baterie takových zarízení a príslusný zpusob CZ298148B6 (cs)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL11931096A IL119310A (en) 1996-09-26 1996-09-26 Cell/tissue culturing device and method
PCT/IL1997/000316 WO1998013469A1 (en) 1996-09-26 1997-09-26 Cell/tissue culturing device and method

Publications (2)

Publication Number Publication Date
CZ104799A3 CZ104799A3 (cs) 1999-08-11
CZ298148B6 true CZ298148B6 (cs) 2007-07-04

Family

ID=11069322

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ0104799A CZ298148B6 (cs) 1996-09-26 1997-09-26 Zarízení na jedno pouzití pro axenické pestování a sklízení bunek a/nebo tkání, baterie takových zarízení a príslusný zpusob

Country Status (14)

Country Link
US (2) US6391638B1 (enExample)
EP (1) EP0938544B1 (enExample)
JP (1) JP3987121B2 (enExample)
AT (1) ATE231912T1 (enExample)
AU (1) AU4318097A (enExample)
CA (1) CA2266851C (enExample)
CZ (1) CZ298148B6 (enExample)
DE (1) DE69718812T2 (enExample)
DK (1) DK0938544T3 (enExample)
ES (1) ES2191851T3 (enExample)
HU (1) HU226908B1 (enExample)
IL (1) IL119310A (enExample)
PL (1) PL190829B1 (enExample)
WO (1) WO1998013469A1 (enExample)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL155588A0 (en) 2003-04-27 2003-11-23 Metabogal Ltd Methods for expression of enzymatically active recombinant lysosomal enzymes in transgenic plant root cells and vectors used thereby
US20050032211A1 (en) * 1996-09-26 2005-02-10 Metabogal Ltd. Cell/tissue culturing device, system and method
FR2781202B1 (fr) * 1998-07-16 2001-01-12 Stedim Sa Poches pour produits fluides bio-pharmaceutiques
GB9915874D0 (en) * 1999-07-08 1999-09-08 Biofence Ltd Microorganism culture
EP1087010B1 (de) * 1999-09-08 2011-11-09 Levitronix LLC Bioreaktor mit Einmalpumpe
US7086778B2 (en) * 2000-10-09 2006-08-08 Levtech, Inc. System using a levitating, rotating pumping or mixing element and related methods
US6635441B2 (en) * 2001-02-08 2003-10-21 Irm, Llc Multi-sample fermentor and method of using same
US20030100945A1 (en) 2001-11-23 2003-05-29 Mindguard Ltd. Implantable intraluminal device and method of using same in treating aneurysms
JP4398125B2 (ja) * 2001-12-05 2010-01-13 高木産業株式会社 細胞・組織培養装置
US7168459B2 (en) * 2002-04-12 2007-01-30 Hynetics Llc Feed bags and methods of use
USD475795S1 (en) 2002-04-15 2003-06-10 Michael K. Johnson Liquid flow bubble release device
IL166340A0 (en) * 2002-07-18 2006-01-16 Kemire Phosphates Pty Ltd Proliferation and delivery apparatus
MXPA05000816A (es) 2002-07-19 2005-04-28 Baxter Int Sistemas y metodos para realizar dialisis peritoneal.
US20100196345A1 (en) * 2003-04-27 2010-08-05 Protalix Production of high mannose proteins in plant culture
US7951557B2 (en) 2003-04-27 2011-05-31 Protalix Ltd. Human lysosomal proteins from plant cell culture
FR2854901B1 (fr) * 2003-05-13 2006-05-26 Rhodia Chimie Sa Procede de preparation d'une suspension de micro-organismes
US20070113474A1 (en) * 2003-05-30 2007-05-24 Biolex, Inc. Bioreactor for growing biological materials supported on a liquid surface
US7176024B2 (en) * 2003-05-30 2007-02-13 Biolex, Inc. Bioreactor for growing biological materials supported on a liquid surface
WO2005006838A2 (en) * 2003-07-21 2005-01-27 Ben-Gurion University Of The Negev Flat panel photobioreactor
US8206973B2 (en) * 2003-09-04 2012-06-26 Gotohti.Com Inc Automated biological growth and dispensing system
AU2004287645A1 (en) 2003-11-06 2005-05-19 Compugen Ltd. Variants of human glycoprotein hormone alpha chain: compositions and uses thereof
CA2552717C (en) * 2004-01-07 2011-11-29 Levtech, Inc. Mixing bag with integral sparger and sensor receiver
US7875448B2 (en) * 2004-01-12 2011-01-25 Single Use Brx, Llc Bioreactor systems and disposable bioreactor
GB0410118D0 (en) * 2004-05-06 2004-06-09 Glaxo Group Ltd Novel bioreactor
CN101001945B (zh) 2004-06-04 2012-02-08 艾克塞勒雷克斯公司 一次性生物反应器系统及方法
JP4570032B2 (ja) * 2004-07-12 2010-10-27 応用地質株式会社 フレキシブル培養バッグを用いる嫌気培養試験装置
US8603805B2 (en) 2005-04-22 2013-12-10 Hyclone Laboratories, Inc. Gas spargers and related container systems
DK1891205T3 (en) * 2005-06-15 2018-03-19 Zhejiang Jinyishengshi Bioengineering Co Ltd SUSPENSION CULTURE CONTAINERS
WO2006138143A1 (en) * 2005-06-15 2006-12-28 Amprotein Corporation Suspension culture vessels
US7628528B2 (en) * 2005-10-26 2009-12-08 PRS Biotech, Inc. Pneumatic bioreactor
US8790913B2 (en) 2005-10-26 2014-07-29 Pbs Biotech, Inc. Methods of using pneumatic bioreactors
US20090047722A1 (en) * 2005-12-09 2009-02-19 Bionavitas, Inc. Systems, devices, and methods for biomass production
GB2433266A (en) 2005-12-16 2007-06-20 Kevin Andrew Auton Cell culture vessel
AU2007217821B2 (en) * 2006-02-21 2012-06-14 The Arizona Board Of Regents, A Body Corporate Acting On Behalf Of Arizona State University Photobioreactor and uses therefor
JP4986659B2 (ja) * 2006-03-23 2012-07-25 藤森工業株式会社 培養袋及び培養器
DE102006018824A1 (de) 2006-04-22 2007-10-25 Bayer Technology Services Gmbh Einweg-Bioreaktor
DE102006022307A1 (de) * 2006-05-11 2007-11-15 Respironics Novametrix, LLC, Wallingford Einwegbioreaktor mit Sensoranordnung
EP1961806B1 (en) * 2006-05-13 2019-03-27 Pall Life Sciences Belgium Disposable bioreactor
WO2007142664A1 (en) * 2006-06-08 2007-12-13 Amprotein Corporation A method to increase dissolved oxygen in a culture vessel
US9512392B2 (en) * 2006-06-08 2016-12-06 Zhejiang Jinyishengshi Bioengineering Co., Ltd Method to increase dissolved oxygen in a culture vessel
EP2049646A2 (en) * 2006-07-14 2009-04-22 Xcellerex, Inc. Environmental containment systems
CA2754719C (en) * 2006-08-10 2013-12-31 Allen C. Barnes Portable biological testing device and method
US10753927B2 (en) 2006-09-22 2020-08-25 ALERE TECHNOLOGIES GmbH Methods for detecting an analyte
US20080131960A1 (en) * 2006-11-15 2008-06-05 Millipore Corporation Self standing bioreactor construction
DE102006062634A1 (de) * 2006-12-23 2008-06-26 Stiftung Alfred-Wegener-Institut für Polar- und Meeresforschung Stiftung des öffentlichen Rechts Kulturvorrichtung für aquatische Organismen
US20100075405A1 (en) * 2007-02-15 2010-03-25 Broadley-James Corporation Bioreactor jacket
WO2008101124A1 (en) * 2007-02-15 2008-08-21 Broadley-James Corporation Sterile bioreactor bag with integrated drive unit
WO2008131019A1 (en) * 2007-04-20 2008-10-30 Bionavitas, Inc. Systems, devices, and, methods for releasing biomass cell components
US7713730B2 (en) 2007-04-24 2010-05-11 Pbs Biotech, Inc. Pneumatic bioreactor
JP5493855B2 (ja) * 2007-04-27 2014-05-14 東洋製罐グループホールディングス株式会社 細胞培養装置、細胞培養システム及び細胞培養方法
ES2660667T3 (es) 2007-05-07 2018-03-23 Protalix Ltd. Biorreactor desechable a gran escala
GB2450337B (en) * 2007-06-19 2009-06-17 Cellexus Biosystems Plc Cell culture and mixing vessel
DK2169054T3 (en) * 2007-07-03 2016-03-07 Idemitsu Kosan Co A vaccine against edema disease in swine
US20090148931A1 (en) * 2007-08-01 2009-06-11 Bionavitas, Inc. Illumination systems, devices, and methods for biomass production
US8742079B2 (en) 2007-08-20 2014-06-03 Protalix Ltd. Saccharide-containing protein conjugates and uses thereof
BE1017763A5 (nl) * 2007-09-24 2009-06-02 Proviron Holding Bioreactor.
US7871462B2 (en) * 2007-10-01 2011-01-18 Baxter International Inc. Dialysis systems having air separation chambers with internal structures to enhance air removal
US8444587B2 (en) 2007-10-01 2013-05-21 Baxter International Inc. Fluid and air handling in blood and dialysis circuits
US7892331B2 (en) 2007-10-01 2011-02-22 Baxter International Inc. Dialysis systems having air separation chambers with internal structures to enhance air removal
US7892332B2 (en) * 2007-10-01 2011-02-22 Baxter International Inc. Dialysis systems having air traps with internal structures to enhance air removal
US20090090022A1 (en) * 2007-10-09 2009-04-09 Hememics Biotechnologies, Inc. Desiccation Chamber and Methods for Drying Biological Materials
US8123947B2 (en) * 2007-10-22 2012-02-28 Baxter International Inc. Priming and air removal systems and methods for dialysis
US8114276B2 (en) 2007-10-24 2012-02-14 Baxter International Inc. Personal hemodialysis system
WO2009132192A2 (en) * 2008-04-25 2009-10-29 Pbs Biotech, Inc. Bioreactor apparatus
US8535936B2 (en) * 2008-06-30 2013-09-17 Twistaferm Vessels for mixing bioprocessing materials
US8057679B2 (en) 2008-07-09 2011-11-15 Baxter International Inc. Dialysis system having trending and alert generation
WO2010062742A2 (en) * 2008-11-03 2010-06-03 The Johns Hopkins University Methods for freparation and use of marrow infiltrating lymphocytes (mils)
DE102009005962A1 (de) 2009-01-23 2010-07-29 Bayer Technology Services Gmbh Begasungssystem
EP2409130B1 (en) * 2009-03-20 2013-12-04 Pbs Biotech, Inc. Automatable aseptic sample withdrawal system
DE102009028059A1 (de) 2009-07-28 2011-02-10 Wacker Chemie Ag Verfahren zur Kultivierung von phototrophen Organismen
WO2011061736A1 (en) 2009-11-17 2011-05-26 Protalix Ltd. Alkaline alpha galactosidase for the treatment of fabry disease
US9194011B2 (en) 2009-11-17 2015-11-24 Protalix Ltd. Stabilized alpha-galactosidase and uses thereof
US8382711B2 (en) 2010-12-29 2013-02-26 Baxter International Inc. Intravenous pumping air management systems and methods
EP2665814B1 (en) 2011-01-20 2017-05-17 Protalix Ltd. Nucleic acid construct for expression of alpha-galactosidase in plants and plant cells
CA2863415C (en) * 2011-03-31 2015-08-11 Rival Societe En Commandite Photobioreactors and culture bags for use therewith
US9376655B2 (en) 2011-09-29 2016-06-28 Life Technologies Corporation Filter systems for separating microcarriers from cell culture solutions
CN104114266B (zh) 2011-09-30 2016-12-14 生命科技股份有限公司 具有膜喷洒器的容器
WO2013114371A1 (en) 2012-02-01 2013-08-08 Protalix Ltd. Dry powder formulations of dnase i
IN2014MN01806A (enExample) 2012-02-19 2015-07-03 Protalix Ltd
CN104379727A (zh) 2012-05-18 2015-02-25 威尔逊沃夫制造公司 改进的用于过继细胞治疗的细胞培养方法
DE102012010155B4 (de) * 2012-05-24 2015-06-11 Pan-Biotech Gmbh Zellkulturbehälter für den Einmalgebrauch
US20140099700A1 (en) * 2012-10-04 2014-04-10 Energaia, Inc. Apparatus and system for bioreactor cultivating microorganisms and reducing carbon dioxide
WO2014074772A1 (en) 2012-11-09 2014-05-15 Heliae Development, Llc Mixotrophic, phototrophic, and heterotrophic combination methods and systems
WO2014074770A2 (en) 2012-11-09 2014-05-15 Heliae Development, Llc Balanced mixotrophy methods
EP2964668B1 (en) 2013-03-06 2019-11-27 Protalix Ltd. Tnf alpha inhibitor polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same
SG10201705494YA (en) * 2013-06-24 2017-08-30 Wolf Wilson Mfg Corp Closed system device and methods for gas permeable cell culture process
WO2015091455A1 (en) * 2013-12-17 2015-06-25 Dpx Holdings B.V. Bioreactor
JP6311306B2 (ja) * 2013-12-26 2018-04-18 株式会社Ihi 細胞回収装置及び細胞培養システム
US20170101633A1 (en) 2014-02-10 2017-04-13 Protalix Ltd. Method of maintaining disease stability in a subject having gaucher's disease
US9079690B1 (en) 2014-06-26 2015-07-14 Advanced Scientifics, Inc. Freezer bag, storage system, and method of freezing
DE102014111913A1 (de) 2014-08-20 2016-02-25 Best Vitality International Ltd. Verfahren zum Gewinnen von Phytoplankton
US10000551B2 (en) 2014-09-11 2018-06-19 Protalix Ltd. Chimeric polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same
US9486590B2 (en) 2014-09-29 2016-11-08 Fenwal, Inc. Automatic purging of air from a fluid processing system
JP2018524718A (ja) 2015-06-25 2018-08-30 ガンブロ・ルンディア・エービーGambro Lundia Ab 分散データベースを有する医療装置システム及び方法
US10625009B2 (en) 2016-02-17 2020-04-21 Baxter International Inc. Airtrap, system and method for removing microbubbles from a fluid stream
US10589197B2 (en) 2016-12-01 2020-03-17 Life Technologies Corporation Microcarrier filter bag assemblies and methods of use
CN110100283B (zh) 2016-12-21 2023-07-04 甘布罗伦迪亚股份公司 包括具有支持外域的安全集群域的信息技术基础架构的医疗设备系统
DE102017107423A1 (de) 2017-04-06 2018-10-11 Agriculture New Energy Gmbh Kultiviereinrichtung sowie Verfahren zum Gewinnen von Phytoplankton
ES2924826T3 (es) * 2017-12-22 2022-10-11 Evologic Tech Gmbh Recipiente de inoculación y biorreactor para cultivos de raíces pilosas
KR102041088B1 (ko) 2018-02-19 2019-11-06 (주)마이크로디지탈 일회용 세포 배양백
CA3107770C (en) 2018-08-16 2023-09-05 Emd Millipore Corporation Closed bioprocessing device
US20220002653A1 (en) * 2018-11-07 2022-01-06 Bluebird Bio, Inc. Cell therapy vessels
DE102018128010B4 (de) * 2018-11-08 2021-02-11 Bastian Steudel Bioreaktor zum Kultivieren von photoautotrophen Mikroorganismen und dessen Verwendung
CA3125250A1 (en) * 2019-01-04 2020-07-09 Oribiotech Ltd Cell processing unit, cell processing system and methods of use thereof
JP2024535811A (ja) 2021-09-13 2024-10-02 プランティバディーズ 組換えタンパク質作製のための遺伝子改変された生物

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS202395B1 (cs) * 1978-12-01 1981-01-30 Zdenek Aunicky Zařízeni na odtahování zralého média při kontinuálních aerobních kultivacích mikroorganismů
CS229179B1 (cs) * 1982-12-22 1984-06-18 Miroslav Ing Cerovsky Zařízení pro kultivací mikroorganismů
EP0200792A1 (de) * 1985-02-01 1986-11-12 Herbert Prof. Dr.-Ing. Märkl Folienfermenter
US4668632A (en) * 1985-02-06 1987-05-26 Vxr, Inc. Sparger and apparatus for and method of growing cells

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1053848A (enExample) *
US467993A (en) 1892-02-02 Alfred jorgensen
US2147271A (en) 1937-07-16 1939-02-14 Schwarz Lab Inc Pure yeast culture apparatus
US2341259A (en) 1941-01-22 1944-02-08 Lummus Co Inoculating method and apparatus
US2836434A (en) * 1952-08-21 1958-05-27 Separator Ab Arrangement for sterile interconnection and sealing of apparatuses in a plant for instance for cultivation of bacteria
US3201327A (en) 1962-08-21 1965-08-17 Sun Oil Co Fermentation apparatus and process
SE371208B (enExample) 1966-10-06 1974-11-11 Sanraku Ocean Co
US3468520A (en) 1967-05-12 1969-09-23 American Cyanamid Co Combination agitation and transfer unit for suspended cells
US3504185A (en) 1968-05-09 1970-03-31 Univ Syracuse Res Corp Apparatus for measuring and controlling cell population density in a liquid medium
GB1284077A (en) 1968-10-18 1972-08-02 British Petroleum Co Process and apparatus for the cultivation of micro-organisms
US3540700A (en) 1969-01-24 1970-11-17 New Brunswick Scientific Co Rotary processing apparatus
DE2059931C3 (de) 1970-12-05 1973-10-18 Knapsack Ag, 5033 Huerth-Knapsack Verfahren zum Verhindern von Schaumausbrüchen aus geschlossenen Reaktionsräumen
US3793154A (en) 1970-12-21 1974-02-19 Univ St Johns Apparatus for gaseous environmental control of batch cultures of micro-organisms
US3950227A (en) 1970-12-21 1976-04-13 St. John's University Batch method of establishing and maintaining a controlled aerobic environment for a microbial culture
CS192067B1 (en) * 1975-12-02 1979-08-31 Drahoslav Pravda Separation blood bag for the sterile preparation of the blood serum for single use
US4179339A (en) 1977-03-02 1979-12-18 Olympus Optical Company, Ltd. Liquid feeder for automatic culture apparatus
US4228243A (en) 1978-07-13 1980-10-14 Toray Industries, Inc. Cell culture propagation apparatus
US4328317A (en) 1980-03-31 1982-05-04 Solargizer International, Inc. Continuous chemical conversion or fermentation apparatus
DE3133314A1 (de) 1981-08-22 1983-03-10 Hoechst Ag, 6000 Frankfurt "vorrichtung zum dispergieren einer zweiten phase in einer ersten phase"
CH663422A5 (de) 1982-05-27 1987-12-15 Chemap Ag Verfahren und fermenter zur zuechtung von gewebezellen.
US4708938A (en) 1984-04-30 1987-11-24 Hickinbotham Winemakers Pty. Ltd. Alcoholic fermentation
US5372945A (en) 1985-06-06 1994-12-13 Alchas; Paul G. Device and method for collecting and processing fat tissue and procuring microvessel endothelial cells to produce endothelial cell product
US4713345A (en) 1985-07-29 1987-12-15 Grain Processing Corporation Fermentation methods and apparatus
EP0224962A1 (en) 1985-11-25 1987-06-10 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur Apparatus for the continuous cultivation of microorganisms in a culture liquid
US5166072A (en) 1986-06-26 1992-11-24 Bayer Aktiengesellschaft Apparatus for the cultivation of immobilized micro-organisms
SE453752B (sv) * 1986-07-04 1988-02-29 Alfa Laval Food & Dairy Eng Forfarande och anordning for aseptisk overforing av en vetskemengd, serskilt vid provtagning
US4717668A (en) 1986-12-12 1988-01-05 Baxter Travenol Laboratories, Inc. Plastic roller bottle for suspension cultures
US5081036A (en) 1987-01-23 1992-01-14 Hoffmann-La Roche Inc. Method and apparatus for cell culture
US4908315A (en) * 1987-03-04 1990-03-13 Agristar, Inc. Integument and method for micropropagation and tissue culturing
GB2202549A (en) * 1987-03-20 1988-09-28 Philip John Whitney Foldable fermenter
IL86442A (en) * 1988-05-19 1992-02-16 Plant Biotec Ltd Air lift fermenter formed from flexible plastic sheets
DE3823711C1 (enExample) * 1988-07-13 1990-04-12 Chemap Ag, Volketswil, Ch
US4931401A (en) 1988-09-01 1990-06-05 La Societe De Recherche Snc Inc. Bioreactor
US5073491A (en) 1988-12-23 1991-12-17 Hoffman-La Roche Inc. Immobilization of cells in alginate beads containing cavities for growth of cells in airlift bioreactors
SU1687604A1 (ru) 1989-01-05 1991-10-30 Всесоюзный научно-исследовательский и технологический институт биологической промышленности Аппарат дл культивировани клеток
US5188946A (en) 1989-01-26 1993-02-23 Biocontrol Systems Incorporated Process and device for sequential microbial enrichment in a single apparatus
US5100801A (en) 1989-01-26 1992-03-31 Biocontrol Systems, Inc. Device for sequential microbial enrichment in a single apparatus
EP0471947A1 (en) 1990-06-29 1992-02-26 Sekisui Chemical Co., Ltd. Culture bag
US5240598A (en) 1990-09-18 1993-08-31 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Microbubble generator for the transfer of oxygen to microbial inocula and microbubble generator immobilized cell reactor
AT394576B (de) 1991-01-16 1992-05-11 Vogelbusch Gmbh Reaktor zur durchfuehrung biologischer reaktionen mittels biokatalysatoren
US5612188A (en) 1991-11-25 1997-03-18 Cornell Research Foundation, Inc. Automated, multicompartmental cell culture system
US5267791A (en) 1991-12-13 1993-12-07 Corning Incorporated Suspended cell culture stirring vessel closure and apparatus
US5409833A (en) 1993-07-01 1995-04-25 Baxter International Inc. Microvessel cell isolation apparatus
US5342781A (en) 1993-07-15 1994-08-30 Su Wei Wen W External-loop perfusion air-lift bioreactor

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS202395B1 (cs) * 1978-12-01 1981-01-30 Zdenek Aunicky Zařízeni na odtahování zralého média při kontinuálních aerobních kultivacích mikroorganismů
CS229179B1 (cs) * 1982-12-22 1984-06-18 Miroslav Ing Cerovsky Zařízení pro kultivací mikroorganismů
EP0200792A1 (de) * 1985-02-01 1986-11-12 Herbert Prof. Dr.-Ing. Märkl Folienfermenter
US4668632A (en) * 1985-02-06 1987-05-26 Vxr, Inc. Sparger and apparatus for and method of growing cells

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PL332483A1 (en) 1999-09-13
DK0938544T3 (da) 2003-05-26
IL119310A0 (en) 1996-12-05
PL190829B1 (pl) 2006-02-28
HUP9904529A3 (en) 2001-07-30
DE69718812D1 (de) 2003-03-06
ES2191851T3 (es) 2003-09-16
WO1998013469A1 (en) 1998-04-02
IL119310A (en) 1999-07-14
CZ104799A3 (cs) 1999-08-11
DE69718812T2 (de) 2004-01-22
US6391638B1 (en) 2002-05-21
JP3987121B2 (ja) 2007-10-03
CA2266851C (en) 2009-07-07
HUP9904529A2 (hu) 2000-04-28
CA2266851A1 (en) 1998-04-02
US20020110915A1 (en) 2002-08-15
HU226908B1 (hu) 2010-03-01
ATE231912T1 (de) 2003-02-15
HK1023361A1 (en) 2000-09-08
EP0938544B1 (en) 2003-01-29
JP2001502526A (ja) 2001-02-27
EP0938544A1 (en) 1999-09-01

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