CZ297316B6 - Steroidní slouceniny a farmaceutický prostredek sjejich obsahem - Google Patents
Steroidní slouceniny a farmaceutický prostredek sjejich obsahem Download PDFInfo
- Publication number
- CZ297316B6 CZ297316B6 CZ20014049A CZ20014049A CZ297316B6 CZ 297316 B6 CZ297316 B6 CZ 297316B6 CZ 20014049 A CZ20014049 A CZ 20014049A CZ 20014049 A CZ20014049 A CZ 20014049A CZ 297316 B6 CZ297316 B6 CZ 297316B6
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- CZ
- Czechia
- Prior art keywords
- cholest
- hydroxy
- tetraene
- homo
- trien
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
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Landscapes
- Health & Medical Sciences (AREA)
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- Pulmonology (AREA)
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- Pregnancy & Childbirth (AREA)
- Psychiatry (AREA)
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- Obesity (AREA)
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Applications Claiming Priority (1)
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| GBGB9910934.0A GB9910934D0 (en) | 1999-05-11 | 1999-05-11 | Chemical compounds |
Publications (2)
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| CZ20014049A3 CZ20014049A3 (cs) | 2002-04-17 |
| CZ297316B6 true CZ297316B6 (cs) | 2006-11-15 |
Family
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| Application Number | Title | Priority Date | Filing Date |
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| CZ20014049A CZ297316B6 (cs) | 1999-05-11 | 2000-05-11 | Steroidní slouceniny a farmaceutický prostredek sjejich obsahem |
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| PT (1) | PT1179005E (enExample) |
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| ZA (1) | ZA200109272B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ298835B6 (cs) * | 2000-05-11 | 2008-02-20 | Research Institute For Medicine And Chemistry Inc. | 2-substituované pregnatrienové a cholatrienové deriváty |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US6908910B2 (en) | 1993-08-06 | 2005-06-21 | The Children's Medical Center Corporation | Estrogenic compounds as anti-mitotic agents |
| GB9910934D0 (en) * | 1999-05-11 | 1999-07-14 | Res Inst Medicine Chem | Chemical compounds |
| US7087592B1 (en) | 1999-08-23 | 2006-08-08 | Entre Med, Inc. | Compositions comprising purified 2-methoxyestradiol and methods of producing same |
| US6995278B2 (en) | 2000-08-18 | 2006-02-07 | Entre Med, Inc. | Antiangiogenic agents |
| US7135581B2 (en) | 2000-08-18 | 2006-11-14 | Entremed, Inc. | Antiangiogenic agents |
| JP2004537499A (ja) * | 2000-11-27 | 2004-12-16 | エントレメッド インコーポレイテッド | 抗血管新生薬 |
| WO2002092100A1 (en) * | 2001-05-11 | 2002-11-21 | Marsden, John, Christopher | 17-(c(ch3) (ch2) o-3c (r4, r5) n (r6, r7))-substituted 19-nor-pregna-1, 3, 5(10)-triene derivatives and their medical use |
| AU2004275693A1 (en) | 2003-05-28 | 2005-04-07 | Entremed, Inc. | Antiangiogenic agents |
| JP2007529426A (ja) | 2004-03-12 | 2007-10-25 | エントレメッド インコーポレイテッド | 抗血管新生薬 |
| CA2646065C (en) | 2006-03-20 | 2014-01-14 | Entremed, Inc. | Disease modifying anti-arthritic activity of 2-methoxyestradiol |
| NZ581081A (en) * | 2007-06-19 | 2012-12-21 | Kythera Biopharmaceuticals Inc | Synthetic deoxycholic acid (dca) or an ester, hydroxamale, or hydroxyamide thereof |
| US8242294B2 (en) | 2007-06-19 | 2012-08-14 | Kythera Biopharmaceuticals, Inc. | Synthetic bile acid compositions and methods |
| JOP20180077A1 (ar) | 2007-06-19 | 2019-01-30 | Kythera Biopharmaceuticals Inc | تركيبات وطرق لحمض صفراوي تخليقي |
| US20080318870A1 (en) | 2007-06-19 | 2008-12-25 | Kythera Biopharmaceuticals, Inc. | Synthetic bile acid compositions and methods |
| WO2013036835A1 (en) * | 2011-09-08 | 2013-03-14 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| RS67266B1 (sr) | 2013-03-13 | 2025-10-31 | Sage Therapeutics Inc | Neuroaktivni steroidi i postupci za njihovu upotrebu |
| WO2015195967A1 (en) | 2014-06-18 | 2015-12-23 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| BR112018000129B1 (pt) | 2015-07-06 | 2024-01-09 | Sage Therapeutics, Inc | Compostos oxiesteróis, seus usos e composição farmacêutica |
| SMT202100476T1 (it) | 2015-07-06 | 2021-09-14 | Sage Therapeutics Inc | Ossisteroli e metodi di uso degli stessi |
| JP6882996B2 (ja) | 2015-07-06 | 2021-06-02 | セージ セラピューティクス， インコーポレイテッド | オキシステロールおよびそれらの使用の方法 |
| SI3436022T1 (sl) | 2016-04-01 | 2022-08-31 | Sage Therapeutics, Inc. | Oksisteroli in postopki za uporabo le-teh |
| WO2017193046A1 (en) | 2016-05-06 | 2017-11-09 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| ES2884071T3 (es) | 2016-07-07 | 2021-12-10 | Sage Therapeutics Inc | 24-hidroxiesteroles sustituidos en 11 para el tratamiento de afecciones relacionadas con NMDA |
| MX392270B (es) | 2016-09-30 | 2025-03-24 | Sage Therapeutics Inc | Oxisteroles sustituidos en c7 y metodos de uso de los mismos. |
| EP4105223B1 (en) | 2016-10-18 | 2025-04-30 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
| CN110267966B (zh) | 2016-10-18 | 2022-07-08 | 萨奇治疗股份有限公司 | 氧甾醇及其使用方法 |
| CN115040524A (zh) * | 2022-07-27 | 2022-09-13 | 深圳市中西医结合医院 | 4-胆甾烯-3-酮用于治疗多发性骨髓瘤骨病的应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4547493A (en) * | 1982-06-11 | 1985-10-15 | Roussel Uclaf | Novel 11β-substituted-19-nor-steroids |
Family Cites Families (5)
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| US3562260A (en) * | 1965-08-23 | 1971-02-09 | Ormonoterapia Richter Spa | 2-carbonyl-estratrienes and method of their preparation |
| GB1267915A (en) * | 1968-05-24 | 1972-03-22 | Glaxo Lab Ltd | Ring a-substituted ring a-aromatic steroids |
| JP2623285B2 (ja) * | 1988-03-09 | 1997-06-25 | 雪印乳業株式会社 | ２（３―ハイドロキシ―１，３，５（１０）―エストリエン―１７―イル）プロピオン酸の製造法 |
| GB9910934D0 (en) * | 1999-05-11 | 1999-07-14 | Res Inst Medicine Chem | Chemical compounds |
| US6967195B2 (en) * | 2000-05-11 | 2005-11-22 | Research Institute For Medicine And Chemistry, Inc. | 2-substituted pregna-1-3,5(10) triene and chola-1,3,5(10) triene derivatives and their biological activity |
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2000
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4547493A (en) * | 1982-06-11 | 1985-10-15 | Roussel Uclaf | Novel 11β-substituted-19-nor-steroids |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ298835B6 (cs) * | 2000-05-11 | 2008-02-20 | Research Institute For Medicine And Chemistry Inc. | 2-substituované pregnatrienové a cholatrienové deriváty |
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| DE60006665D1 (de) | 2003-12-24 |
| JP2002544137A (ja) | 2002-12-24 |
| EP1179005B1 (en) | 2003-11-19 |
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| NO20015520D0 (no) | 2001-11-12 |
| NO319949B1 (no) | 2005-10-03 |
| CN1158297C (zh) | 2004-07-21 |
| IL146442A0 (en) | 2002-07-25 |
| US20050171075A1 (en) | 2005-08-04 |
| AU4596000A (en) | 2000-11-21 |
| HK1046001A1 (en) | 2002-12-20 |
| ZA200109272B (en) | 2003-02-26 |
| GB9910934D0 (en) | 1999-07-14 |
| EP1179005A1 (en) | 2002-02-13 |
| KR20020013542A (ko) | 2002-02-20 |
| HUP0201047A3 (en) | 2003-07-28 |
| KR100690040B1 (ko) | 2007-03-09 |
| CZ20014049A3 (cs) | 2002-04-17 |
| IL146442A (en) | 2006-10-05 |
| CA2373443A1 (en) | 2000-11-16 |
| PT1179005E (pt) | 2004-04-30 |
| WO2000068246A1 (en) | 2000-11-16 |
| CN1358193A (zh) | 2002-07-10 |
| HUP0201047A2 (en) | 2002-08-28 |
| ES2207509T3 (es) | 2004-06-01 |
| ATE254629T1 (de) | 2003-12-15 |
| DK1179005T3 (da) | 2004-03-01 |
| NO20015520L (no) | 2002-01-09 |
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| MM4A | Patent lapsed due to non-payment of fee |
Effective date: 20100511 |