GB9910934D0 - Chemical compounds - Google Patents

Chemical compounds

Info

Publication number
GB9910934D0
GB9910934D0 GBGB9910934.0A GB9910934A GB9910934D0 GB 9910934 D0 GB9910934 D0 GB 9910934D0 GB 9910934 A GB9910934 A GB 9910934A GB 9910934 D0 GB9910934 D0 GB 9910934D0
Authority
GB
United Kingdom
Prior art keywords
sup
group
hydrogen atom
hydroxyl
araliphatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB9910934.0A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Institute for Medicine and Chemistry Inc
Original Assignee
Research Institute for Medicine and Chemistry Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Institute for Medicine and Chemistry Inc filed Critical Research Institute for Medicine and Chemistry Inc
Priority to GBGB9910934.0A priority Critical patent/GB9910934D0/en
Publication of GB9910934D0 publication Critical patent/GB9910934D0/en
Priority to AU45960/00A priority patent/AU779743B2/en
Priority to NZ515482A priority patent/NZ515482A/en
Priority to DE60006665T priority patent/DE60006665T2/de
Priority to IL14644200A priority patent/IL146442A0/xx
Priority to PT00927569T priority patent/PT1179005E/pt
Priority to ES00927569T priority patent/ES2207509T3/es
Priority to KR1020017014382A priority patent/KR100690040B1/ko
Priority to EP00927569A priority patent/EP1179005B1/en
Priority to HU0201047A priority patent/HUP0201047A3/hu
Priority to AT00927569T priority patent/ATE254629T1/de
Priority to CNB008095175A priority patent/CN1158297C/zh
Priority to DK00927569T priority patent/DK1179005T3/da
Priority to HK02105910.4A priority patent/HK1046001B/en
Priority to JP2000616220A priority patent/JP2002544137A/ja
Priority to CZ20014049A priority patent/CZ297316B6/cs
Priority to CA002373443A priority patent/CA2373443A1/en
Priority to PCT/GB2000/001813 priority patent/WO2000068246A1/en
Priority to ZA200109272A priority patent/ZA200109272B/xx
Priority to IL146442A priority patent/IL146442A/en
Priority to NO20015520A priority patent/NO319949B1/no
Priority to US09/926,491 priority patent/US6881730B1/en
Priority to US11/055,620 priority patent/US20050171075A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Pregnancy & Childbirth (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Steroid Compounds (AREA)
GBGB9910934.0A 1999-05-11 1999-05-11 Chemical compounds Ceased GB9910934D0 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
GBGB9910934.0A GB9910934D0 (en) 1999-05-11 1999-05-11 Chemical compounds
PCT/GB2000/001813 WO2000068246A1 (en) 1999-05-11 2000-05-11 Steroid compounds with a c17-alkyl side chain and an aromatic a-ring for use in therapy
AT00927569T ATE254629T1 (de) 1999-05-11 2000-05-11 C17-alkyl substituierte steroidverbindungen mit einem aromatischen a-ring zur therapeutischen verwendung
DK00927569T DK1179005T3 (da) 1999-05-11 2000-05-11 Steroidforbindelser med en C17-alkyl-sidekæde og en aromatisk A-ring til anvendelse i terapi
DE60006665T DE60006665T2 (de) 1999-05-11 2000-05-11 C17-alkyl substituierte steroidverbindungen mit einem aromatischen a-ring zur therapeutischen verwendung
IL14644200A IL146442A0 (en) 1999-05-11 2000-05-11 Steroid compounds with a c17-alkyl side chain and an aromatic a-ring for use in therapy
PT00927569T PT1179005E (pt) 1999-05-11 2000-05-11 Compostos esteroides com uma cadeia alquilica em c-17 e um anel-a aromatico para utilizacao em terapia
ES00927569T ES2207509T3 (es) 1999-05-11 2000-05-11 Compuestos esteroides con una cadena lateral alquilica c17 y un anillo a aromatico para uso en terapia.
KR1020017014382A KR100690040B1 (ko) 1999-05-11 2000-05-11 치료용 ｃ17-알킬 측쇄 및 방향족 ａ-고리를 갖는스테로이드 화합물
EP00927569A EP1179005B1 (en) 1999-05-11 2000-05-11 Steroid compounds with a c17-alkyl side chain and an aromatic a-ring for use in therapy
HU0201047A HUP0201047A3 (en) 1999-05-11 2000-05-11 Steroid compounds with a c17-alkyl side chain and an aromatic a-ring, process for their preparation and pharmaceutical compositions containing the compounds
AU45960/00A AU779743B2 (en) 1999-05-11 2000-05-11 Steroid compounds with a C17-alkyl side chain and an aromatic A-ring for use in therapy
CNB008095175A CN1158297C (zh) 1999-05-11 2000-05-11 用于治疗的具有c-17烷基侧链和芳香a-环的甾族化合物
NZ515482A NZ515482A (en) 1999-05-11 2000-05-11 Steroid compounds with a C17-alkyl side chain and an aromatic A-ring for use in therapy
HK02105910.4A HK1046001B (en) 1999-05-11 2000-05-11 Steroid compounds with A C17-ALKYL side chain and aromatic A-ring for treatment
JP2000616220A JP2002544137A (ja) 1999-05-11 2000-05-11 Ｃ１７アルキル側鎖および芳香族ａ環をもつ治療に使用するステロイド化合物
CZ20014049A CZ297316B6 (cs) 1999-05-11 2000-05-11 Steroidní slouceniny a farmaceutický prostredek sjejich obsahem
CA002373443A CA2373443A1 (en) 1999-05-11 2000-05-11 Steroid compounds with a c17-alkyl side chain and an aromatic a-ring for use in therapy
ZA200109272A ZA200109272B (en) 1999-05-11 2001-11-09 Steriod compounds with a C17-alkyl side chain and an aromatic a-ring for use in theraphy.
IL146442A IL146442A (en) 1999-05-11 2001-11-11 Steroid compounds with C17-alkyl side chain and aromatic ring A for use in healing
NO20015520A NO319949B1 (no) 1999-05-11 2001-11-12 Steroidforbindelser med en C17-alkyl sidekjede og en aromatisk A-ring for anvendelse i terapi, samt deres fremstilling.
US09/926,491 US6881730B1 (en) 1999-05-11 2003-05-11 Steroid compounds with a c17-alkyl side chain and an aromatic a-ring for use in therapy
US11/055,620 US20050171075A1 (en) 1999-05-11 2005-02-11 Steroid compounds with a c17-alkyl side chain and an aromatic a-ring for use in therapy

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9910934.0A GB9910934D0 (en) 1999-05-11 1999-05-11 Chemical compounds

Publications (1)

Publication Number Publication Date
GB9910934D0 true GB9910934D0 (en) 1999-07-14

Family

ID=10853250

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB9910934.0A Ceased GB9910934D0 (en) 1999-05-11 1999-05-11 Chemical compounds

Country Status (21)

Country Link
US (2) US6881730B1 (enExample)
EP (1) EP1179005B1 (enExample)
JP (1) JP2002544137A (enExample)
KR (1) KR100690040B1 (enExample)
CN (1) CN1158297C (enExample)
AT (1) ATE254629T1 (enExample)
AU (1) AU779743B2 (enExample)
CA (1) CA2373443A1 (enExample)
CZ (1) CZ297316B6 (enExample)
DE (1) DE60006665T2 (enExample)
DK (1) DK1179005T3 (enExample)
ES (1) ES2207509T3 (enExample)
GB (1) GB9910934D0 (enExample)
HK (1) HK1046001B (enExample)
HU (1) HUP0201047A3 (enExample)
IL (2) IL146442A0 (enExample)
NO (1) NO319949B1 (enExample)
NZ (1) NZ515482A (enExample)
PT (1) PT1179005E (enExample)
WO (1) WO2000068246A1 (enExample)
ZA (1) ZA200109272B (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6908910B2 (en) 1993-08-06 2005-06-21 The Children's Medical Center Corporation Estrogenic compounds as anti-mitotic agents
GB9910934D0 (en) * 1999-05-11 1999-07-14 Res Inst Medicine Chem Chemical compounds
US7087592B1 (en) 1999-08-23 2006-08-08 Entre Med, Inc. Compositions comprising purified 2-methoxyestradiol and methods of producing same
NZ523042A (en) * 2000-05-11 2004-05-28 Res Inst Medicine Chem 2-substituted pregna-1, 3, 5 (10) -triene and chola-1, 3, 5 (10)-triene derivatives and their biological activity
US6995278B2 (en) 2000-08-18 2006-02-07 Entre Med, Inc. Antiangiogenic agents
US7135581B2 (en) 2000-08-18 2006-11-14 Entremed, Inc. Antiangiogenic agents
JP2004537499A (ja) * 2000-11-27 2004-12-16 エントレメッド インコーポレイテッド 抗血管新生薬
WO2002092100A1 (en) * 2001-05-11 2002-11-21 Marsden, John, Christopher 17-(c(ch3) (ch2) o-3c (r4, r5) n (r6, r7))-substituted 19-nor-pregna-1, 3, 5(10)-triene derivatives and their medical use
AU2004275693A1 (en) 2003-05-28 2005-04-07 Entremed, Inc. Antiangiogenic agents
JP2007529426A (ja) 2004-03-12 2007-10-25 エントレメッド インコーポレイテッド 抗血管新生薬
CA2646065C (en) 2006-03-20 2014-01-14 Entremed, Inc. Disease modifying anti-arthritic activity of 2-methoxyestradiol
NZ581081A (en) * 2007-06-19 2012-12-21 Kythera Biopharmaceuticals Inc Synthetic deoxycholic acid (dca) or an ester, hydroxamale, or hydroxyamide thereof
US8242294B2 (en) 2007-06-19 2012-08-14 Kythera Biopharmaceuticals, Inc. Synthetic bile acid compositions and methods
JOP20180077A1 (ar) 2007-06-19 2019-01-30 Kythera Biopharmaceuticals Inc تركيبات وطرق لحمض صفراوي تخليقي
US20080318870A1 (en) 2007-06-19 2008-12-25 Kythera Biopharmaceuticals, Inc. Synthetic bile acid compositions and methods
WO2013036835A1 (en) * 2011-09-08 2013-03-14 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
RS67266B1 (sr) 2013-03-13 2025-10-31 Sage Therapeutics Inc Neuroaktivni steroidi i postupci za njihovu upotrebu
WO2015195967A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
BR112018000129B1 (pt) 2015-07-06 2024-01-09 Sage Therapeutics, Inc Compostos oxiesteróis, seus usos e composição farmacêutica
SMT202100476T1 (it) 2015-07-06 2021-09-14 Sage Therapeutics Inc Ossisteroli e metodi di uso degli stessi
JP6882996B2 (ja) 2015-07-06 2021-06-02 セージ セラピューティクス， インコーポレイテッド オキシステロールおよびそれらの使用の方法
SI3436022T1 (sl) 2016-04-01 2022-08-31 Sage Therapeutics, Inc. Oksisteroli in postopki za uporabo le-teh
WO2017193046A1 (en) 2016-05-06 2017-11-09 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
ES2884071T3 (es) 2016-07-07 2021-12-10 Sage Therapeutics Inc 24-hidroxiesteroles sustituidos en 11 para el tratamiento de afecciones relacionadas con NMDA
MX392270B (es) 2016-09-30 2025-03-24 Sage Therapeutics Inc Oxisteroles sustituidos en c7 y metodos de uso de los mismos.
EP4105223B1 (en) 2016-10-18 2025-04-30 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
CN110267966B (zh) 2016-10-18 2022-07-08 萨奇治疗股份有限公司 氧甾醇及其使用方法
CN115040524A (zh) * 2022-07-27 2022-09-13 深圳市中西医结合医院 4-胆甾烯-3-酮用于治疗多发性骨髓瘤骨病的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3562260A (en) * 1965-08-23 1971-02-09 Ormonoterapia Richter Spa 2-carbonyl-estratrienes and method of their preparation
GB1267915A (en) * 1968-05-24 1972-03-22 Glaxo Lab Ltd Ring a-substituted ring a-aromatic steroids
FR2528434B1 (fr) * 1982-06-11 1985-07-19 Roussel Uclaf Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament
JP2623285B2 (ja) * 1988-03-09 1997-06-25 雪印乳業株式会社 ２（３―ハイドロキシ―１，３，５（１０）―エストリエン―１７―イル）プロピオン酸の製造法
GB9910934D0 (en) * 1999-05-11 1999-07-14 Res Inst Medicine Chem Chemical compounds
US6967195B2 (en) * 2000-05-11 2005-11-22 Research Institute For Medicine And Chemistry, Inc. 2-substituted pregna-1-3,5(10) triene and chola-1,3,5(10) triene derivatives and their biological activity

Also Published As

Publication number Publication date
AU779743B2 (en) 2005-02-10
NZ515482A (en) 2004-05-28
DE60006665D1 (de) 2003-12-24
JP2002544137A (ja) 2002-12-24
EP1179005B1 (en) 2003-11-19
HK1046001B (en) 2004-12-24
US6881730B1 (en) 2005-04-19
DE60006665T2 (de) 2004-10-07
NO20015520D0 (no) 2001-11-12
NO319949B1 (no) 2005-10-03
CN1158297C (zh) 2004-07-21
IL146442A0 (en) 2002-07-25
US20050171075A1 (en) 2005-08-04
AU4596000A (en) 2000-11-21
HK1046001A1 (en) 2002-12-20
ZA200109272B (en) 2003-02-26
EP1179005A1 (en) 2002-02-13
KR20020013542A (ko) 2002-02-20
HUP0201047A3 (en) 2003-07-28
KR100690040B1 (ko) 2007-03-09
CZ20014049A3 (cs) 2002-04-17
IL146442A (en) 2006-10-05
CZ297316B6 (cs) 2006-11-15
CA2373443A1 (en) 2000-11-16
PT1179005E (pt) 2004-04-30
WO2000068246A1 (en) 2000-11-16
CN1358193A (zh) 2002-07-10
HUP0201047A2 (en) 2002-08-28
ES2207509T3 (es) 2004-06-01
ATE254629T1 (de) 2003-12-15
DK1179005T3 (da) 2004-03-01
NO20015520L (no) 2002-01-09

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