CZ293745B6 - Polynukleotidová sekvence, DNA, polypeptid, farmaceutický prostředek, vektor, hostitel, expresivní systém, protilátka, způsob čištění proteinu a hybridom - Google Patents

Polynukleotidová sekvence, DNA, polypeptid, farmaceutický prostředek, vektor, hostitel, expresivní systém, protilátka, způsob čištění proteinu a hybridom Download PDF

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Publication number
CZ293745B6
CZ293745B6 CZ20014056A CZ20014056A CZ293745B6 CZ 293745 B6 CZ293745 B6 CZ 293745B6 CZ 20014056 A CZ20014056 A CZ 20014056A CZ 20014056 A CZ20014056 A CZ 20014056A CZ 293745 B6 CZ293745 B6 CZ 293745B6
Authority
CZ
Czechia
Prior art keywords
polypeptide
sequence
antibody
polynucleotide sequence
gly
Prior art date
Application number
CZ20014056A
Other languages
Czech (cs)
English (en)
Inventor
Tohru Takahashi
Ryuta Koishi
Ichiro Kawashima
Nobufusa Serizava
Original Assignee
Sankyo Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP30380994A external-priority patent/JP3337178B2/ja
Application filed by Sankyo Company Limited filed Critical Sankyo Company Limited
Publication of CZ293745B6 publication Critical patent/CZ293745B6/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0051—Oxidoreductases (1.) acting on a sulfur group of donors (1.8)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5431—IL-11
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
    • C12N9/506—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses derived from RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/35—Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/95—Fusion polypeptide containing a motif/fusion for degradation (ubiquitin fusions, PEST sequence)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
CZ20014056A 1994-07-13 1995-07-13 Polynukleotidová sekvence, DNA, polypeptid, farmaceutický prostředek, vektor, hostitel, expresivní systém, protilátka, způsob čištění proteinu a hybridom CZ293745B6 (cs)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP16105394 1994-07-13
JP21839294 1994-09-13
JP30380994A JP3337178B2 (ja) 1994-07-13 1994-12-07 クローバーイエローベインウイルスプロテアーゼ

Publications (1)

Publication Number Publication Date
CZ293745B6 true CZ293745B6 (cs) 2004-07-14

Family

ID=27321781

Family Applications (2)

Application Number Title Priority Date Filing Date
CZ20014056A CZ293745B6 (cs) 1994-07-13 1995-07-13 Polynukleotidová sekvence, DNA, polypeptid, farmaceutický prostředek, vektor, hostitel, expresivní systém, protilátka, způsob čištění proteinu a hybridom
CZ19951808A CZ293582B6 (cs) 1994-07-13 1995-07-13 Polynukleotidová sekvence, vektor, který ji obsahuje, hostitel a expresivní systém s obsahem tohoto vektoru, polypeptid, fúzní protein, způsob výroby polynukleotidové sekvence a její použití

Family Applications After (1)

Application Number Title Priority Date Filing Date
CZ19951808A CZ293582B6 (cs) 1994-07-13 1995-07-13 Polynukleotidová sekvence, vektor, který ji obsahuje, hostitel a expresivní systém s obsahem tohoto vektoru, polypeptid, fúzní protein, způsob výroby polynukleotidové sekvence a její použití

Country Status (14)

Country Link
US (3) US5955072A (OSRAM)
EP (2) EP0700999A3 (OSRAM)
KR (1) KR100417026B1 (OSRAM)
CN (4) CN1090676C (OSRAM)
AU (1) AU696358B2 (OSRAM)
CA (1) CA2153720A1 (OSRAM)
CZ (2) CZ293745B6 (OSRAM)
FI (1) FI953422L (OSRAM)
HU (2) HU0202280D0 (OSRAM)
IL (1) IL114582A0 (OSRAM)
MX (1) MX9503070A (OSRAM)
NO (1) NO952763L (OSRAM)
NZ (1) NZ272561A (OSRAM)
TW (1) TW459046B (OSRAM)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904539D0 (sv) * 1999-12-10 1999-12-10 Alphahelix Ab Method and device for the handling of samples and reagents
FR2824334B1 (fr) * 2001-05-03 2003-10-10 Coletica Procede pour tester une substance eventuellement active dans le domaine de la lipolyse et son utilisation principalement cosmetique
US20050053942A1 (en) * 2002-06-24 2005-03-10 Sakari Kauppinen Methods and systems for detection and isolation of a nucleotide sequence
CN101184780B (zh) 2005-05-05 2012-10-03 森馨香料公司 β-葡聚糖和甘露聚糖的制备
EP2468881A3 (en) 2005-07-21 2012-08-15 Abbott Laboratories Multiple gene expression including sorf contructs and methods with polyproteins, pro-proteins, and proteolysis
US20100035300A1 (en) * 2006-02-27 2010-02-11 Wang Andrew H-J Producing a Target Protein Using Intramolecular Cleavage by TEV Protease
US9206431B2 (en) * 2007-09-27 2015-12-08 Academia Sinica Kit for producing recombinant tag-cleavable fusion proteins via at least two different expression vectors allow protein production in two different species host cells
US8501449B2 (en) * 2007-12-04 2013-08-06 Proteon Therapeutics, Inc. Recombinant elastase proteins and methods of manufacturing and use thereof
WO2011053699A1 (en) * 2009-10-30 2011-05-05 Abbott Laboratories Sorf constructs and multiple gene expression

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2059482T3 (es) * 1987-12-23 1994-11-16 Boehringer Ingelheim Int Expresion de la proteasa p2a de hrv2 codificada por virus.
US5162601A (en) * 1989-11-22 1992-11-10 The Upjohn Company Plant potyvirus expression vector with a gene for protease
US6077694A (en) * 1990-09-21 2000-06-20 The United States Of America As Represented By The Department Of Health And Human Services Method for over-expression and rapid purification of biosynthetic proteins
JP2759895B2 (ja) * 1991-08-30 1998-05-28 サノフィ インターロイキン１βプロテアーゼをコードするＤＮＡ配列単離体
WO1995021249A1 (en) * 1994-02-03 1995-08-10 The Scripps Research Institute A cassette to accumulate multiple proteins through synthesis of a self-processing polypeptide

Also Published As

Publication number Publication date
US6307038B1 (en) 2001-10-23
EP0700999A3 (en) 1997-04-16
EP0700999A2 (en) 1996-03-13
NO952763L (no) 1996-01-15
HU0202280D0 (OSRAM) 2002-09-28
FI953422A7 (fi) 1996-01-14
CN1090676C (zh) 2002-09-11
EP1251176A3 (en) 2002-12-18
NZ272561A (en) 1997-03-24
CN1385532A (zh) 2002-12-18
EP1251176A2 (en) 2002-10-23
HU9502114D0 (en) 1995-09-28
TW459046B (en) 2001-10-11
CN1126759A (zh) 1996-07-17
CZ293582B6 (cs) 2004-06-16
US6743611B2 (en) 2004-06-01
US5955072A (en) 1999-09-21
AU2497095A (en) 1996-01-25
HUT72922A (en) 1996-06-28
CA2153720A1 (en) 1996-01-14
KR100417026B1 (ko) 2004-05-17
FI953422A0 (fi) 1995-07-13
CN1320689A (zh) 2001-11-07
NO952763D0 (no) 1995-07-12
CN1385529A (zh) 2002-12-18
FI953422L (fi) 1996-01-14
US20030176688A1 (en) 2003-09-18
IL114582A0 (en) 1995-11-27
MX9503070A (es) 1997-01-31
CZ180895A3 (en) 1996-02-14
AU696358B2 (en) 1998-09-10

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MM4A Patent lapsed due to non-payment of fee

Effective date: 20050713