CZ188794A3 - Process for preparing 3-carbonylandrostadiene-17-carboxamides and novel intermediate - Google Patents
Process for preparing 3-carbonylandrostadiene-17-carboxamides and novel intermediate Download PDFInfo
- Publication number
- CZ188794A3 CZ188794A3 CZ941887A CZ188794A CZ188794A3 CZ 188794 A3 CZ188794 A3 CZ 188794A3 CZ 941887 A CZ941887 A CZ 941887A CZ 188794 A CZ188794 A CZ 188794A CZ 188794 A3 CZ188794 A3 CZ 188794A3
- Authority
- CZ
- Czechia
- Prior art keywords
- formula
- compound
- alkyl
- cyanide
- process according
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0066—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83228092A | 1992-02-07 | 1992-02-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CZ188794A3 true CZ188794A3 (en) | 1994-12-15 |
Family
ID=25261209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CZ941887A CZ188794A3 (en) | 1992-02-07 | 1993-02-05 | Process for preparing 3-carbonylandrostadiene-17-carboxamides and novel intermediate |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP0643724A4 (xx) |
| JP (1) | JPH07505140A (xx) |
| KR (1) | KR950700319A (xx) |
| CN (1) | CN1078475A (xx) |
| AP (1) | AP9600790A0 (xx) |
| AU (1) | AU666177B2 (xx) |
| BG (1) | BG98955A (xx) |
| BR (1) | BR9305837A (xx) |
| CA (1) | CA2129342A1 (xx) |
| CZ (1) | CZ188794A3 (xx) |
| FI (1) | FI943660A0 (xx) |
| HU (1) | HUT68303A (xx) |
| IL (1) | IL104602A (xx) |
| MA (1) | MA22788A1 (xx) |
| MX (1) | MX9300676A (xx) |
| NO (1) | NO942925L (xx) |
| NZ (1) | NZ249382A (xx) |
| OA (1) | OA10090A (xx) |
| RU (1) | RU94045824A (xx) |
| SI (1) | SI9300065A (xx) |
| TW (1) | TW327175B (xx) |
| WO (1) | WO1993016097A1 (xx) |
| ZA (1) | ZA93801B (xx) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9206413D0 (en) * | 1992-03-24 | 1992-05-06 | Smithkline Beecham Corp | N-t-butyl-androst-3,5-diene-17b-carboxamide-3-carboxylic acid polymorph a |
| US5641765A (en) * | 1992-11-18 | 1997-06-24 | Smithkline Beecham Corporation | 17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase |
| US5683995A (en) * | 1992-11-18 | 1997-11-04 | Smithkline Beecham Corporation | 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA883034B (en) * | 1987-04-29 | 1989-03-29 | Smithkline Beckman Corp | Steroid 5-alpha-reductase inhibitors |
| IL104601A0 (en) * | 1992-02-07 | 1993-07-08 | Smithkline Beecham Corp | Process for the preparation of steroidal dienes |
-
1993
- 1993-02-03 IL IL104602A patent/IL104602A/xx not_active IP Right Cessation
- 1993-02-05 JP JP5514208A patent/JPH07505140A/ja active Pending
- 1993-02-05 HU HU9402303A patent/HUT68303A/hu unknown
- 1993-02-05 CZ CZ941887A patent/CZ188794A3/cs unknown
- 1993-02-05 BR BR9305837A patent/BR9305837A/pt not_active Application Discontinuation
- 1993-02-05 AP APAP/P/1996/000790A patent/AP9600790A0/en unknown
- 1993-02-05 NZ NZ249382A patent/NZ249382A/en unknown
- 1993-02-05 RU RU94045824/04A patent/RU94045824A/ru unknown
- 1993-02-05 ZA ZA93801A patent/ZA93801B/xx unknown
- 1993-02-05 SI SI19939300065A patent/SI9300065A/sl unknown
- 1993-02-05 CA CA002129342A patent/CA2129342A1/en not_active Abandoned
- 1993-02-05 WO PCT/US1993/001068 patent/WO1993016097A1/en not_active Application Discontinuation
- 1993-02-05 EP EP93904946A patent/EP0643724A4/en not_active Ceased
- 1993-02-05 AU AU36126/93A patent/AU666177B2/en not_active Ceased
- 1993-02-05 MA MA23079A patent/MA22788A1/fr unknown
- 1993-02-06 CN CN 93102531 patent/CN1078475A/zh active Pending
- 1993-02-06 TW TW082100820A patent/TW327175B/zh active
- 1993-02-08 MX MX9300676A patent/MX9300676A/es unknown
-
1994
- 1994-08-02 KR KR1019940702656A patent/KR950700319A/ko not_active Application Discontinuation
- 1994-08-03 OA OA60547A patent/OA10090A/en unknown
- 1994-08-04 BG BG98955A patent/BG98955A/bg unknown
- 1994-08-05 NO NO942925A patent/NO942925L/no unknown
- 1994-08-05 FI FI943660A patent/FI943660A0/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU94045824A (ru) | 1996-07-10 |
| KR950700319A (ko) | 1995-01-16 |
| EP0643724A1 (en) | 1995-03-22 |
| FI943660A (fi) | 1994-08-05 |
| AU3612693A (en) | 1993-09-03 |
| BG98955A (bg) | 1995-06-30 |
| HUT68303A (en) | 1995-06-28 |
| AP9600790A0 (en) | 1996-04-30 |
| WO1993016097A1 (en) | 1993-08-19 |
| SI9300065A (en) | 1993-09-30 |
| EP0643724A4 (en) | 1995-05-10 |
| NO942925L (no) | 1994-08-08 |
| JPH07505140A (ja) | 1995-06-08 |
| CN1078475A (zh) | 1993-11-17 |
| CA2129342A1 (en) | 1993-08-19 |
| IL104602A (en) | 1997-07-13 |
| FI943660A0 (fi) | 1994-08-05 |
| HU9402303D0 (en) | 1994-10-28 |
| NZ249382A (en) | 1996-05-28 |
| BR9305837A (pt) | 1997-02-18 |
| NO942925D0 (xx) | 1994-08-05 |
| AU666177B2 (en) | 1996-02-01 |
| ZA93801B (en) | 1993-11-05 |
| MX9300676A (es) | 1994-07-29 |
| IL104602A0 (en) | 1993-07-08 |
| MA22788A1 (fr) | 1993-10-01 |
| OA10090A (en) | 1996-12-18 |
| TW327175B (en) | 1998-02-21 |
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