CY324A - Benzodiazepine derivatives - Google Patents

Benzodiazepine derivatives

Info

Publication number
CY324A
CY324A CY32465A CY32465A CY324A CY 324 A CY324 A CY 324A CY 32465 A CY32465 A CY 32465A CY 32465 A CY32465 A CY 32465A CY 324 A CY324 A CY 324A
Authority
CY
Cyprus
Prior art keywords
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
CY32465A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CY324A publication Critical patent/CY324A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/42Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/16Saturated compounds containing keto groups bound to acyclic carbon atoms containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/74Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/20Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/26Preparation from compounds already containing the benzodiazepine skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CY32465A 1959-12-10 1965-11-03 Benzodiazepine derivatives CY324A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85856459A 1959-12-10 1959-12-10
US260560A 1960-01-15 1960-01-15
US2468660A 1960-04-26 1960-04-26
US3873260A 1960-06-27 1960-06-27

Publications (1)

Publication Number Publication Date
CY324A true CY324A (en) 1965-11-03

Family

ID=27485190

Family Applications (1)

Application Number Title Priority Date Filing Date
CY32465A CY324A (en) 1959-12-10 1965-11-03 Benzodiazepine derivatives

Country Status (11)

Country Link
BE (4) BE598013A (de)
BR (1) BR6024755D0 (de)
CH (9) CH408045A (de)
CY (1) CY324A (de)
DE (5) DE1288609B (de)
ES (2) ES263123A1 (de)
GB (13) GB972968A (de)
MY (1) MY6500178A (de)
NL (2) NL6412251A (de)
OA (7) OA00817A (de)
SE (2) SE310887B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1300114B (de) * 1963-05-29 1969-07-31 American Home Prod Verfahren zur Herstellung von 5-Chlor-2-(2'-hydroxylamino-acetamido)-benzophenon
GB1333501A (en) * 1971-03-05 1973-10-10 Ravizza Spa Process for the preparation of 7-chlorobenzodiazepine de rivatives
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
US4820834A (en) * 1984-06-26 1989-04-11 Merck & Co., Inc. Benzodiazepine analogs
WO2002098865A2 (fr) * 2001-06-07 2002-12-12 Neuro3D Inhibiteurs des phosphodiesterases des nucleotides cycliques, preparation et utilisations de ces inhibiteurs
EP2402310A1 (de) * 2002-05-24 2012-01-04 Millennium Pharmaceuticals, Inc. CCR9-Hemmer und Verwendungsverfahren dafür

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2893992A (en) * 1959-07-07 I ii i i

Also Published As

Publication number Publication date
ES263123A1 (es) 1961-06-01
OA00953A (fr) 1968-03-22
CH414653A (de) 1966-06-15
SE318283B (de) 1969-12-08
DE1290143B (de) 1969-03-06
OA00959A (fr) 1968-03-22
GB972968A (en) 1964-10-21
CH396016A (de) 1965-07-31
GB972973A (en) 1964-10-21
CH414652A (de) 1966-06-15
BE598015A (fr) 1961-06-09
CH418342A (de) 1966-08-15
CH408940A (de) 1966-03-15
CH418341A (de) 1966-08-15
BR6024755D0 (pt) 1973-05-24
MY6500178A (en) 1965-12-31
GB972962A (en) 1964-10-21
GB972963A (en) 1964-10-21
CH408029A (de) 1966-02-28
NL6412250A (de) 1966-01-25
ES263124A1 (es) 1961-06-01
BE598012A (fr) 1961-06-09
BE598013A (fr) 1961-06-09
GB972970A (en) 1964-10-21
DE1288609B (de) 1969-02-06
CH408045A (de) 1966-02-28
GB972972A (en) 1964-10-21
GB972969A (en) 1964-10-21
GB972961A (en) 1964-10-21
OA00958A (fr) 1968-03-22
GB972976A (en) 1964-10-21
NL6412251A (de) 1966-01-25
GB972964A (en) 1964-10-21
BE598008A (fr) 1961-06-09
OA02385A (fr) 1970-05-05
OA02384A (fr) 1970-05-05
DE1445908A1 (de) 1969-04-17
OA00816A (fr) 1967-11-15
SE310887B (de) 1969-05-19
OA00817A (fr) 1967-11-15
GB972965A (en) 1964-10-21
DE1288610B (de) 1969-02-06
GB972966A (en) 1964-10-21
DE1445073A1 (de) 1968-10-31
CH411910A (de) 1966-04-30
GB972967A (en) 1964-10-21

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