CY1969A - Azabicyclo quinolone carboxylic acids - Google Patents

Azabicyclo quinolone carboxylic acids

Info

Publication number
CY1969A
CY1969A CY196997A CY196997A CY1969A CY 1969 A CY1969 A CY 1969A CY 196997 A CY196997 A CY 196997A CY 196997 A CY196997 A CY 196997A CY 1969 A CY1969 A CY 1969A
Authority
CY
Cyprus
Prior art keywords
carboxylic acids
quinolone carboxylic
azabicyclo
alkyl
methyl
Prior art date
Application number
CY196997A
Other languages
English (en)
Inventor
Katherine Elizabeth Brighty
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CY1969A publication Critical patent/CY1969A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
CY196997A 1989-08-16 1997-09-05 Azabicyclo quinolone carboxylic acids CY1969A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/003489 WO1991002526A1 (en) 1989-08-16 1989-08-16 Azabicyclo quinolone carboxylic acids

Publications (1)

Publication Number Publication Date
CY1969A true CY1969A (en) 1997-09-05

Family

ID=22215165

Family Applications (2)

Application Number Title Priority Date Filing Date
CY196997A CY1969A (en) 1989-08-16 1997-09-05 Azabicyclo quinolone carboxylic acids
CY1999010C CY99010I2 (en) 1989-08-16 1999-05-24 Azabicyclo quinolone carboxylic acids

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY1999010C CY99010I2 (en) 1989-08-16 1999-05-24 Azabicyclo quinolone carboxylic acids

Country Status (29)

Country Link
EP (1) EP0413455B1 (pl)
JP (2) JPH072734B2 (pl)
KR (1) KR930004844B1 (pl)
CN (1) CN1025192C (pl)
AT (1) ATE124040T1 (pl)
AU (1) AU623801B2 (pl)
BA (1) BA98299A (pl)
CA (2) CA2127561C (pl)
CY (2) CY1969A (pl)
CZ (1) CZ281127B6 (pl)
DD (1) DD298399A5 (pl)
DE (3) DE69020262T2 (pl)
DK (1) DK0413455T3 (pl)
EG (1) EG19251A (pl)
ES (1) ES2074131T4 (pl)
FI (2) FI108228B (pl)
GR (1) GR3017072T3 (pl)
HU (2) HU219403B (pl)
IE (1) IE66202B1 (pl)
IL (1) IL95331A (pl)
LU (2) LU90310I2 (pl)
NL (2) NL980033I2 (pl)
NO (1) NO300214B1 (pl)
NZ (1) NZ234920A (pl)
PL (1) PL166381B1 (pl)
PT (1) PT94998B (pl)
RU (1) RU2049777C1 (pl)
WO (1) WO1991002526A1 (pl)
ZA (1) ZA906450B (pl)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0449445A3 (en) * 1990-03-27 1993-08-25 Pfizer Inc. Preparation of beta-ketoesters useful in preparing quinolone antibiotics
FR2675144B1 (fr) * 1991-04-10 1995-06-16 Bouchara Sa Nouvelles quinolones difluorees - leur procede de preparation et les compositions pharmaceutiques en renfermant.
ES2136086T3 (es) * 1991-06-19 1999-11-16 Pfizer Agentes antibacterianos con azaespiroquinolona.
US5256791A (en) * 1992-03-02 1993-10-26 Pfizer Inc. Preparation of intermediates in the synthesis of quinoline antibiotics
EG20543A (en) * 1992-10-30 1999-07-31 Procter & Gamble Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones
US5527910A (en) * 1992-12-30 1996-06-18 Cheil Foods & Chemicals, Inc. Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria
US5591766A (en) * 1993-12-03 1997-01-07 Cheil Foods & Chemicals, Inc. Solid oral formulations of pyridone carboxylic acids
ES2173175T3 (es) * 1994-02-04 2002-10-16 Dainippon Pharmaceutical Co Derivado de acido piridonacarboxilico sustituido con un grupo amino biciclico, ester del mismo, sal del mismo, y amina biciclica como intermedio para su preparacion.
JPH08213881A (ja) * 1995-02-02 1996-08-20 Fujitsu Ltd 周波数制御回路
DK0807630T3 (da) * 1995-02-02 2003-09-01 Daiichi Seiyaku Co Heterocykliske forbindelser
TW466237B (en) * 1995-02-07 2001-12-01 Daiichi Seiyaku Co Heterocyclic spiro-derivative
DK0789697T3 (da) * 1995-06-06 1998-10-19 Pfizer Krystalform af vandfrit 7-([1alfa, 5alfa, 6alfa,]-6-amino-3-azabicyclo[3.1.0]hex-3-yl)-6-fluor-1-(2,4-difluorphenyl)-1,4-d
WO1997000268A1 (en) * 1995-06-15 1997-01-03 Pfizer Inc. Process for preparing derivatives of azabicyclo naphthyridine carboxylic acid comprising a dipeptide
PT882725E (pt) * 1996-02-09 2003-04-30 Toyama Chemical Co Ltd Derivados do acido quinolonacarboxilico ou os seus sais
AP788A (en) * 1996-08-26 1999-12-03 Pfizer Novel crystal form of anhydrous 7-(1a, 5a, 6a)-6-Amino-3-Azabicyclo(3.1.0) hex-3-YI)-6-Fluoro-1-(2,4- Difluorophenyl)-1,4-Dihydro-4-Oxo-1, 8-Naphthyridine-3-Carboxylic Acid, Methanesulfonic acid salt.
TW519542B (en) * 1996-09-27 2003-02-01 Daiichi Seiyaku Co Bicyclic amine derivative
ATE267191T1 (de) * 1996-10-25 2004-06-15 Daiichi Seiyaku Co Tricyclische aminderivate
MA24500A1 (fr) 1997-03-21 1998-10-01 Lg Life Sciences Ltd Derive du sel d'acide carboxylique de naphthyridine .
US20020032216A1 (en) 1997-03-21 2002-03-14 Lg Chemical Ltd. Salt of naphthyridine carboxylic acid derivative
DE19733439A1 (de) * 1997-08-02 1999-02-04 Bayer Ag Neue 6-endo-Amino-3-azabicyclo(3.1.0)hexande, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung von Chinolon- und Naphthyridincarbonsäure-Derviaten mit verbesserten Eigenschaften
PT1015445E (pt) 1997-09-15 2009-05-14 Procter & Gamble Quinolonas antimicrobianas, suas composições e seus usos
US6184380B1 (en) * 1999-01-25 2001-02-06 Pfizer Inc. Process for preparing naphthyridones and intermediates
PA8464701A1 (es) * 1998-01-16 2000-09-29 Pfizer Prod Inc Procedimiento e intermedios para preparar naftiridonas
US7019142B2 (en) 1998-01-16 2006-03-28 Pfizer Inc. Process for preparing naphthyridones and intermediates
GB9820405D0 (en) 1998-09-18 1998-11-11 Smithkline Beecham Plc Process
EP1161956A4 (en) 1999-03-17 2005-03-16 Daiichi Seiyaku Co DRUG COMPOSITIONS
GB9920919D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel compound
GB9920917D0 (en) 1999-09-03 1999-11-10 Sb Pharmco Inc Novel process
NZ525571A (en) 2000-12-14 2004-09-24 Procter & Gamble Antimicrobial quinolones
IL155678A0 (en) 2000-12-14 2003-11-23 Procter & Gamble Antimicrobial 2-pyridones, their compositions and uses
KR100517638B1 (ko) 2002-04-08 2005-09-28 주식회사 엘지생명과학 게미플록사신 산염의 새로운 제조방법
US7399779B2 (en) 2002-07-08 2008-07-15 Ranbaxy Laboratories Limited 3,6-disubstituted azabicyclo [3.1.0] hexane derivatives useful as muscarinic receptor antagonists
ATE423769T1 (de) 2002-08-23 2009-03-15 Ranbaxy Lab Ltd Fluor- und sulfonylaminohaltige, 3,6- disubstituierte azabicyclo 3.1.0 hexanderivate als muscarinrezeptorantagonisten
US7517905B2 (en) 2003-04-09 2009-04-14 Ranbaxy Laboratories Limited Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists
BR0318242A (pt) 2003-04-10 2006-04-04 Ranbaxy Lab Ltd derivados de azabiciclo hexano substituìdo como antagonistas de receptores muscarìnicos e processo para sua preparação
US20070021487A1 (en) 2003-04-11 2007-01-25 Mohammad Salman Azabicyclo derivatives as muscarinic receptor antagonists
KR101077755B1 (ko) 2003-09-10 2011-10-27 교린 세이야꾸 가부시키 가이샤 7-(4-치환-3-시클로프로필아미노메틸-1-피롤리디닐)퀴놀론카르본산 유도체
EP1670759A1 (en) * 2003-09-18 2006-06-21 Ranbaxy Laboratories Limited PROCESS FOR THE PREPARATION OF (1a, 5a, 6a)-6-AMINOME THYL-3-BENZYL-3-AZABICYCLO 3.1.0 HEXANE
TWI391378B (zh) * 2006-03-16 2013-04-01 Astellas Pharma Inc 喹啉酮衍生物或其製藥學上可被容許之鹽
BRPI0709220A2 (pt) 2006-03-28 2011-07-12 Procter & Gamble processo de acoplamento para preparo de intermediários de quinolona
SI2001862T1 (sl) 2006-03-28 2011-10-28 Warner Chilcott Co Llc Soli malatov in polimorfi (3S, 5S)-7-(3-amino-5-metil-piperidinil)-1-ciklopropil-1,4-dihidro-8-metoksi- 4-okso-3-kinolinkarboksline kisline
US7902227B2 (en) * 2007-07-27 2011-03-08 Janssen Pharmaceutica Nv. C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents
US9133116B2 (en) 2010-09-28 2015-09-15 Panacea Biotec Ltd. Bicyclic compounds
EP3856735B1 (en) * 2018-10-05 2023-09-06 New York University Fused bicyclic heterocycles as therapeutic agents
CN112442084B (zh) * 2020-12-03 2022-09-09 国药集团致君（深圳）制药有限公司 一种抗菌药中间体的制备方法
CN113307768B (zh) * 2021-04-29 2023-12-12 中国农业科学院兰州畜牧与兽药研究所 喹诺酮类衍生物及其制备方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0676400B2 (ja) * 1987-08-25 1994-09-28 大日本製薬株式会社 新規ピリドンカルボン酸誘導体、そのエステルおよびその塩
JP2844079B2 (ja) * 1988-05-23 1999-01-06 塩野義製薬株式会社 ピリドンカルボン酸系抗菌剤
US4973091A (en) * 1989-09-20 1990-11-27 Truth Incorporated Sliding patio door dual point latch and lock

Also Published As

Publication number Publication date
DE69020262D1 (de) 1995-07-27
DE69020262T2 (de) 1995-10-26
CN1049501A (zh) 1991-02-27
CY99010I2 (en) 2010-07-28
CA2023217C (en) 1996-12-10
AU6104290A (en) 1991-02-21
NO920599D0 (no) 1992-02-14
KR930004844B1 (ko) 1993-06-09
PL286484A1 (en) 1991-05-20
FI920632A0 (fi) 1992-02-14
NL980032I1 (nl) 1999-02-01
JPH072734B2 (ja) 1995-01-18
HU219403B (hu) 2001-04-28
ATE124040T1 (de) 1995-07-15
IE902950A1 (en) 1991-02-27
DD298399A5 (de) 1992-02-20
CA2127561C (en) 1998-07-28
NL980032I2 (nl) 1999-05-03
RU2049777C1 (ru) 1995-12-10
DE19875050I2 (de) 2009-05-28
CA2127561A1 (en) 1991-02-17
LU90310I2 (fr) 1999-01-25
DE19875052I2 (de) 2009-05-28
FI103879B1 (fi) 1999-10-15
CZ402790A3 (en) 1996-04-17
ZA906450B (en) 1992-03-25
HK1000207A1 (en) 1998-02-06
AU623801B2 (en) 1992-05-21
PT94998B (pt) 1997-05-28
CZ281127B6 (cs) 1996-06-12
JPH0386875A (ja) 1991-04-11
IL95331A (en) 1995-07-31
FI108228B (fi) 2001-12-14
NL980033I2 (nl) 1999-05-03
FI964520A0 (fi) 1996-11-11
PT94998A (pt) 1991-04-18
GR3017072T3 (en) 1995-11-30
EG19251A (en) 1994-09-29
CN1025192C (zh) 1994-06-29
ES2074131T4 (es) 1996-05-01
LU90311I2 (fr) 1999-01-25
EP0413455A2 (en) 1991-02-20
NZ234920A (en) 1992-06-25
CA2023217A1 (en) 1991-02-17
KR910004572A (ko) 1991-03-28
FI964520L (fi) 1996-11-11
JPH0819099B2 (ja) 1996-02-28
NO920599L (no) 1992-04-14
DK0413455T3 (da) 1995-08-14
JPH07149758A (ja) 1995-06-13
IE66202B1 (en) 1995-12-13
NL980033I1 (nl) 1999-02-01
ES2074131T3 (es) 1995-09-01
EP0413455B1 (en) 1995-06-21
WO1991002526A1 (en) 1991-03-07
PL166381B1 (pl) 1995-05-31
FI103879B (fi) 1999-10-15
IL95331A0 (en) 1991-06-30
BA98299A (bs) 2001-09-14
NO300214B1 (no) 1997-04-28
HU211681A9 (en) 1995-12-28
EP0413455A3 (en) 1991-10-09

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