CY1968A - Triazole antifungal agents - Google Patents

Triazole antifungal agents

Info

Publication number
CY1968A
CY1968A CY196897A CY196897A CY1968A CY 1968 A CY1968 A CY 1968A CY 196897 A CY196897 A CY 196897A CY 196897 A CY196897 A CY 196897A CY 1968 A CY1968 A CY 1968A
Authority
CY
Cyprus
Prior art keywords
antifungal agents
triazole antifungal
triazole
agents
antifungal
Prior art date
Application number
CY196897A
Other languages
English (en)
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10642109&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1968(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of CY1968A publication Critical patent/CY1968A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/08—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
CY196897A 1988-08-13 1997-09-05 Triazole antifungal agents CY1968A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888819308A GB8819308D0 (en) 1988-08-13 1988-08-13 Triazole antifungal agents

Publications (1)

Publication Number Publication Date
CY1968A true CY1968A (en) 1997-09-05

Family

ID=10642109

Family Applications (1)

Application Number Title Priority Date Filing Date
CY196897A CY1968A (en) 1988-08-13 1997-09-05 Triazole antifungal agents

Country Status (39)

Country Link
US (2) US5116844A (zh)
EP (1) EP0357241B1 (zh)
JP (2) JPH0786100B2 (zh)
KR (1) KR930002729B1 (zh)
CN (1) CN1029231C (zh)
AP (1) AP104A (zh)
AR (1) AR246963A1 (zh)
AU (1) AU602638B2 (zh)
BG (1) BG60865B1 (zh)
CA (1) CA1341325C (zh)
CY (1) CY1968A (zh)
CZ (1) CZ284318B6 (zh)
DD (1) DD284010A5 (zh)
DE (1) DE68913105T2 (zh)
DK (1) DK172471B1 (zh)
ES (1) ES2062009T4 (zh)
FI (1) FI96859C (zh)
GB (1) GB8819308D0 (zh)
HK (1) HK1000320A1 (zh)
HU (2) HU205348B (zh)
IE (1) IE61412B1 (zh)
IL (1) IL91231A (zh)
IN (1) IN175438B (zh)
IS (1) IS1586B (zh)
LV (1) LV10714B (zh)
MA (1) MA21610A1 (zh)
MX (1) MX17169A (zh)
MY (1) MY105092A (zh)
NO (1) NO174101C (zh)
NZ (1) NZ230283A (zh)
OA (1) OA09126A (zh)
PE (1) PE1591A1 (zh)
PL (2) PL163756B1 (zh)
PT (1) PT91440B (zh)
RO (1) RO108453B1 (zh)
RU (2) RU1836366C (zh)
SK (1) SK476189A3 (zh)
YU (1) YU47093B (zh)
ZA (1) ZA896151B (zh)

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US5278175A (en) * 1990-02-02 1994-01-11 Pfizer Inc. Triazole antifungal agents
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GB9121456D0 (en) * 1991-10-10 1991-11-27 Pfizer Ltd Triazole antifungal agents
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NZ270418A (en) * 1994-02-07 1997-09-22 Eisai Co Ltd Polycyclic triazole & imidazole derivatives, antifungal compositions
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CA2180091A1 (en) * 1995-07-08 1997-01-09 Hiroki Kodama Optically active triazole derivative, process for producing the same, antifungal agent, and method for using the same
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KR100572996B1 (ko) * 2003-08-12 2006-04-25 한국화학연구원 불소화 비닐 에테르 측쇄기를 갖는 아졸계 살균제 화합물및 그의 제조방법
AR061889A1 (es) 2006-07-13 2008-10-01 Medichem Sa Proceso mejorado para la preparacion de voriconazol
DK2650291T3 (en) 2006-08-07 2017-10-23 Palau Pharma Sa Crystalline, anti-fungal compounds
WO2009137611A2 (en) * 2008-05-06 2009-11-12 Board Of Regents, The University Of Texas System Treatment of pulmonary fungal infection with voriconazole via inhalation
MX2012000212A (es) * 2009-07-08 2012-01-25 Bayer Cropscience Ag Derivados de fenil (oxi/tio) alcanol sustituidos.
WO2011064558A2 (en) 2009-11-30 2011-06-03 Cipla Limited Pharmaceutical composition
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US9056855B2 (en) 2010-10-28 2015-06-16 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
RU2478106C2 (ru) * 2010-11-25 2013-03-27 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Казанский (Приволжский) Федеральный Университет" (ФГАОУ ВПО КФУ) СОЕДИНЕНИЯ НА ОСНОВЕ КОМПЛЕКСОВ ГИПЕРРАЗВЕТВЛЕННЫХ ПОЛИМЕРОВ Boltorn H, ОБЛАДАЮЩИЕ АНТИКАНДИДОЗНОЙ АКТИВНОСТЬЮ, И СПОСОБ ИХ ПОЛУЧЕНИЯ
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CN105884743B (zh) * 2011-06-19 2019-08-06 威尔金制药(Nc)有限公司 金属酶抑制剂化合物
KR20140040235A (ko) 2011-06-19 2014-04-02 비아멧 파마슈티컬즈, 인코포레이티드 금속효소 억제제 화합물
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JP2017531636A (ja) 2014-10-02 2017-10-26 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 殺菌剤として有用な新規トリアゾール誘導体
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Also Published As

Publication number Publication date
RU2095358C1 (ru) 1997-11-10
FI96859B (fi) 1996-05-31
KR930002729B1 (ko) 1993-04-09
EP0357241A1 (en) 1990-03-07
LV10714A (lv) 1995-06-20
DK394589A (da) 1990-02-14
GB8819308D0 (en) 1988-09-14
HK1000320A1 (en) 1998-02-27
BG60865B1 (bg) 1996-05-31
AU3893089A (en) 1990-03-22
DK172471B1 (da) 1998-09-07
RU1836366C (ru) 1993-08-23
FI96859C (fi) 1996-09-10
DE68913105T2 (de) 1994-05-26
ZA896151B (en) 1991-03-27
CN1029231C (zh) 1995-07-05
IE892582L (en) 1990-02-13
PT91440A (pt) 1990-03-08
MY105092A (en) 1994-08-30
IE61412B1 (en) 1994-11-02
NO893248D0 (no) 1989-08-11
PL162953B1 (pl) 1994-01-31
OA09126A (fr) 1991-10-31
JPH0786100B2 (ja) 1995-09-20
SK280775B6 (sk) 2000-07-11
ES2062009T4 (es) 2006-07-01
RO108453B1 (ro) 1994-05-31
PT91440B (pt) 1995-05-04
HUT52089A (en) 1990-06-28
US5364938A (en) 1994-11-15
US5116844A (en) 1992-05-26
DD284010A5 (de) 1990-10-31
PE1591A1 (es) 1991-03-16
ES2062009T3 (es) 1994-12-16
AU602638B2 (en) 1990-10-18
HU205348B (en) 1992-04-28
CZ476189A3 (cs) 1998-09-16
FI893809A (fi) 1990-02-14
JPH07173154A (ja) 1995-07-11
KR900003157A (ko) 1990-03-23
JP2713394B2 (ja) 1998-02-16
SK476189A3 (en) 2000-07-11
DK394589D0 (da) 1989-08-11
CZ284318B6 (cs) 1998-10-14
IS1586B (is) 1996-03-01
NO893248L (no) 1990-02-14
MX17169A (es) 1993-08-01
YU158789A (en) 1991-04-30
BG89519A (bg) 1993-12-24
AP104A (en) 1990-11-02
IL91231A0 (en) 1990-03-19
HU211511A9 (en) 1995-11-28
IS3499A7 (is) 1990-02-14
EP0357241B1 (en) 1994-02-16
IL91231A (en) 1994-08-26
AP8900135A0 (en) 1989-10-31
CA1341325C (en) 2001-12-11
IN175438B (zh) 1995-06-17
PL163756B1 (pl) 1994-04-29
NO174101C (no) 1994-03-16
DE68913105D1 (de) 1994-03-24
FI893809A0 (fi) 1989-08-11
JPH02104583A (ja) 1990-04-17
YU47093B (sh) 1994-12-28
MA21610A1 (fr) 1990-04-01
NZ230283A (en) 1991-02-26
LV10714B (en) 1995-12-20
AR246963A1 (es) 1994-10-31
NO174101B (no) 1993-12-06
CN1040795A (zh) 1990-03-28

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