CY1125187T1 - Εκχυλισματα φυτων εμπλουτισμενα με παραγωγα ιπολαμιιδης ως ανοσοκατασταλτικα για τη θεραπεια ανοσολογικων διαταραχων - Google Patents
Εκχυλισματα φυτων εμπλουτισμενα με παραγωγα ιπολαμιιδης ως ανοσοκατασταλτικα για τη θεραπεια ανοσολογικων διαταραχωνInfo
- Publication number
- CY1125187T1 CY1125187T1 CY20221100223T CY221100223T CY1125187T1 CY 1125187 T1 CY1125187 T1 CY 1125187T1 CY 20221100223 T CY20221100223 T CY 20221100223T CY 221100223 T CY221100223 T CY 221100223T CY 1125187 T1 CY1125187 T1 CY 1125187T1
- Authority
- CY
- Cyprus
- Prior art keywords
- treatment
- immune disorders
- ipolamide
- immunosuppressants
- derivatives
- Prior art date
Links
- 208000026278 immune system disease Diseases 0.000 title abstract 2
- 229960003444 immunosuppressant agent Drugs 0.000 title 1
- 239000003018 immunosuppressive agent Substances 0.000 title 1
- 239000000419 plant extract Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 241000196324 Embryophyta Species 0.000 abstract 1
- 241001530100 Stachytarpheta Species 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/47—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/92—Unsaturated compounds containing keto groups containing —CHO groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Η ακόλουθη εφεύρεση περιγράφει νέες και εφευρετικές απομονωμένες ενώσεις και τη διαδικασία παραγωγής ενώσεων και εκχυλισμάτων με ανοσοκατασταλτική δράση, από φυτά του γένους Stachytarpheta. Με αυτόν τον τρόπο, η παρούσα αίτηση περιγράφει επίσης νέες και εφευρετικές συνθέσεις και τη χρήση τους για τη θεραπεία ανοσολογικών διαταραχών. Η παρούσα εφεύρεση είναι στους τομείς της φαρμακευτικής, της ιατρικής και της χημείας.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR102017003318A BR102017003318A2 (pt) | 2017-02-17 | 2017-02-17 | compostos, processo de produção de compostos, extrato enriquecido, frações ativas de extrato enriquecido, processo de produção de extrato enriquecido, método de seleção de biomassa vegetal para produção de extrato enriquecido, composição e uso para tratamento de desordens imunológicas |
PCT/BR2018/050037 WO2018148816A2 (en) | 2017-02-17 | 2018-02-19 | Compounds, process of production of compounds, enriched extract, enriched extract active fractions, enriched extract process of production, method for selecting vegetal biomass for enriched extract production, composition and use for treatment of immunological disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1125187T1 true CY1125187T1 (el) | 2023-06-09 |
Family
ID=61282932
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20221100223T CY1125187T1 (el) | 2017-02-17 | 2022-03-21 | Εκχυλισματα φυτων εμπλουτισμενα με παραγωγα ιπολαμιιδης ως ανοσοκατασταλτικα για τη θεραπεια ανοσολογικων διαταραχων |
Country Status (27)
Country | Link |
---|---|
US (1) | US20200231561A1 (el) |
EP (2) | EP4001270A1 (el) |
JP (2) | JP7349362B2 (el) |
KR (1) | KR20190121790A (el) |
CN (1) | CN110475768B (el) |
AU (1) | AU2018221956B2 (el) |
BR (2) | BR102017003318A2 (el) |
CA (1) | CA3052713A1 (el) |
CL (1) | CL2019002309A1 (el) |
CO (1) | CO2019008891A2 (el) |
CY (1) | CY1125187T1 (el) |
DK (1) | DK3583103T3 (el) |
EC (1) | ECSP19058322A (el) |
ES (1) | ES2909387T3 (el) |
HR (1) | HRP20220377T1 (el) |
IL (1) | IL268732A (el) |
LT (1) | LT3583103T (el) |
MX (2) | MX2019009655A (el) |
PE (1) | PE20200449A1 (el) |
PL (1) | PL3583103T3 (el) |
PT (1) | PT3583103T (el) |
RS (1) | RS63162B1 (el) |
SA (1) | SA519402443B1 (el) |
SG (1) | SG11201907375VA (el) |
SI (1) | SI3583103T1 (el) |
WO (1) | WO2018148816A2 (el) |
ZA (1) | ZA201906106B (el) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115304652A (zh) * | 2022-07-25 | 2022-11-08 | 福建华闽晟业生物科技有限公司 | 一种利用巨菌草制备野芝麻新甙的方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3703543A (en) * | 1969-11-05 | 1972-11-21 | American Home Prod | Hydroxamic acids of alicyclic amino acids |
DE3030477C2 (de) * | 1980-08-12 | 1986-10-16 | Dr. Willmar Schwabe GmbH & Co, 7500 Karlsruhe | Iridoid-Derivate, Verfahren zu ihrer Herstellung und deren Verwendung |
JPH0366682A (ja) * | 1989-08-04 | 1991-03-22 | Tsumura & Co | 新規イリドイド誘導体 |
AU651849B2 (en) * | 1990-10-09 | 1994-08-04 | Tsumura & Co. | Iridoid derivatives and their use as medicines |
DE19644422C2 (de) * | 1996-10-25 | 2000-06-15 | Stefan Schulz | Verwendung von Terpenen zur Behandlung von Autoimmunkrankheiten und bei Transplantat-Abstoßungsreaktionen |
EP1145709A1 (de) * | 2000-04-14 | 2001-10-17 | Laboratoires Serobiologiques | Verwendung von Naturstoffen zur Herstellung von kosmetischen Zubereitungen |
AU2003224361B2 (en) * | 2002-05-10 | 2008-01-31 | Council Of Scientific And Industrial Research | Hepatoprotective activity of 2'-p-Hydroxybenzoylmussaenosidic acid |
EP1371372A1 (de) * | 2002-06-08 | 2003-12-17 | Cognis Iberia, S.L. | Verwendung von Wirkstoffgemischen enthaltend Tocopherole und Extrakte des Harpagophytum procumbens zur Herstellung eines Medikamentes gegen rheumatische Arthritis |
JP2008024670A (ja) | 2006-07-24 | 2008-02-07 | Daiwa Kagaku Kogyo Kk | 害虫駆除剤 |
BRPI0700767B8 (pt) * | 2007-02-15 | 2021-05-25 | Ache Laboratorios Farmaceuticos Sa | composição farmacêutica, produto farmaceutico, processo para obtenção de compostos farmaceuticos e uso de tais compostos para o tratamento do vitiligo |
CN103120699B (zh) * | 2011-11-18 | 2017-04-19 | 天津市国际生物医药联合研究院 | 环烯醚萜类化合物在制备抗sars的药物中的应用 |
CN103690551A (zh) * | 2013-07-18 | 2014-04-02 | 江苏大学 | 猪殃殃中环烯醚萜苷提取物及其提取方法和医药用途 |
DE102015102020A1 (de) * | 2015-02-12 | 2016-08-18 | Renate Wilmanowicz | Immunologisch aktives Phyto-Gemisch und seine Anwendung bei der Prävention und in einem Verfahren zur Behandlung von Effloreszenzen |
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2017
- 2017-02-17 BR BR102017003318A patent/BR102017003318A2/pt active Search and Examination
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2018
- 2018-02-19 EP EP21215133.6A patent/EP4001270A1/en active Pending
- 2018-02-19 CA CA3052713A patent/CA3052713A1/en active Pending
- 2018-02-19 ES ES18707229T patent/ES2909387T3/es active Active
- 2018-02-19 MX MX2019009655A patent/MX2019009655A/es unknown
- 2018-02-19 EP EP18707229.3A patent/EP3583103B1/en active Active
- 2018-02-19 LT LTEPPCT/BR2018/050037T patent/LT3583103T/lt unknown
- 2018-02-19 RS RS20220241A patent/RS63162B1/sr unknown
- 2018-02-19 KR KR1020197026718A patent/KR20190121790A/ko not_active Application Discontinuation
- 2018-02-19 DK DK18707229.3T patent/DK3583103T3/da active
- 2018-02-19 JP JP2019544005A patent/JP7349362B2/ja active Active
- 2018-02-19 SI SI201830594T patent/SI3583103T1/sl unknown
- 2018-02-19 SG SG11201907375VA patent/SG11201907375VA/en unknown
- 2018-02-19 WO PCT/BR2018/050037 patent/WO2018148816A2/en active Application Filing
- 2018-02-19 US US16/486,683 patent/US20200231561A1/en active Pending
- 2018-02-19 AU AU2018221956A patent/AU2018221956B2/en active Active
- 2018-02-19 PL PL18707229.3T patent/PL3583103T3/pl unknown
- 2018-02-19 HR HRP20220377TT patent/HRP20220377T1/hr unknown
- 2018-02-19 PT PT187072293T patent/PT3583103T/pt unknown
- 2018-02-19 CN CN201880018995.0A patent/CN110475768B/zh active Active
- 2018-02-19 BR BR112019017128A patent/BR112019017128A2/pt unknown
- 2018-02-19 PE PE2019001711A patent/PE20200449A1/es unknown
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2019
- 2019-08-13 MX MX2022012282A patent/MX2022012282A/es unknown
- 2019-08-14 CL CL2019002309A patent/CL2019002309A1/es unknown
- 2019-08-14 EC ECSENADI201958322A patent/ECSP19058322A/es unknown
- 2019-08-15 IL IL26873219A patent/IL268732A/en unknown
- 2019-08-15 CO CONC2019/0008891A patent/CO2019008891A2/es unknown
- 2019-08-15 SA SA519402443A patent/SA519402443B1/ar unknown
- 2019-09-16 ZA ZA2019/06106A patent/ZA201906106B/en unknown
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2022
- 2022-03-21 CY CY20221100223T patent/CY1125187T1/el unknown
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2023
- 2023-01-25 JP JP2023009384A patent/JP2023061959A/ja active Pending
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