CY1114171T1 - Συζευγματα αλλεργιογονων γατας και χρησεις τους - Google Patents
Συζευγματα αλλεργιογονων γατας και χρησεις τουςInfo
- Publication number
- CY1114171T1 CY1114171T1 CY20131100638T CY131100638T CY1114171T1 CY 1114171 T1 CY1114171 T1 CY 1114171T1 CY 20131100638 T CY20131100638 T CY 20131100638T CY 131100638 T CY131100638 T CY 131100638T CY 1114171 T1 CY1114171 T1 CY 1114171T1
- Authority
- CY
- Cyprus
- Prior art keywords
- cat
- antigen
- compositions
- vlp
- conjunctions
- Prior art date
Links
- 230000002009 allergenic effect Effects 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 6
- 102000036639 antigens Human genes 0.000 abstract 6
- 108091007433 antigens Proteins 0.000 abstract 6
- 241000282326 Felis catus Species 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 239000013566 allergen Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 208000001840 Dandruff Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 230000005875 antibody response Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000005180 public health Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Η παρούσα εφεύρεση είναι στο πεδίο της ιατρικής, της δημόσιας υγείας, της ανοσολογίας, της μοριακής βιολογίας και της ιολογίας. Η εφεύρεση παρέχει συνθέσεις οι οποίες περιλαμβάνουν ένα ιόμορφο σωματίδιο (VLΡ) ή ένα σωμάτιο ιού και τουλάχιστον ένα αντιγόνο, ειδικότερα τουλάχιστον ένα αντιγόνο γάτας, και πιο συγκεκριμένα τουλάχιστον ένα αντιγόνο γάτας το οποίο είναι ένα ανθρώπινο αλλεργιογόνο. Σε ορισμένες υλοποιήσεις, το αντιγόνο είναι ένα Fel d1 αντιγόνο ή ένα θραύσμα αυτού, ομοιοπολικά συνδεδεμένο με το VLP. Η εφεύρεση επίσης παρέχει μεθόδους για παρασκευή των συνθέσεων. Οι συνθέσεις της εφεύρεσης επάγουν αποτελεσματικές άνοσες αποκρίσεις, ειδικότερα αποκρίσεις αντισωμάτων, σε θηλαστικά, ειδικότερα ανθρώπους. Οι συνθέσεις και μέθοδοι της εφεύρεσης είναι χρήσιμες στην παραγωγή εμβολίων, ειδικότερα για την αντιμετώπιση και/ή πρόληψη αλλεργιών σε πιτυρίδα γάτας και άλλα αντιγόνα και αλλεργιογόνα γάτας.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66291805P | 2005-03-18 | 2005-03-18 | |
EP06725140.5A EP1868642B1 (en) | 2005-03-18 | 2006-03-17 | Cat allergen fusion proteins and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1114171T1 true CY1114171T1 (el) | 2016-08-31 |
Family
ID=36843236
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20131100638T CY1114171T1 (el) | 2005-03-18 | 2013-07-26 | Συζευγματα αλλεργιογονων γατας και χρησεις τους |
Country Status (19)
Country | Link |
---|---|
US (3) | US7767212B2 (el) |
EP (1) | EP1868642B1 (el) |
JP (2) | JP5302671B2 (el) |
KR (1) | KR20070112225A (el) |
CN (2) | CN103203016A (el) |
AU (1) | AU2006224529B2 (el) |
BR (1) | BRPI0608455A2 (el) |
CA (1) | CA2599218C (el) |
CY (1) | CY1114171T1 (el) |
DK (1) | DK1868642T3 (el) |
ES (1) | ES2424229T3 (el) |
IL (1) | IL185103A0 (el) |
MX (1) | MX2007011160A (el) |
NZ (1) | NZ561040A (el) |
PL (1) | PL1868642T3 (el) |
PT (1) | PT1868642E (el) |
RU (1) | RU2414239C2 (el) |
WO (1) | WO2006097530A2 (el) |
ZA (1) | ZA200707413B (el) |
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RU2324704C2 (ru) * | 2002-07-17 | 2008-05-20 | Цитос Байотекнолоджи Аг | Молекулярные массивы антигенов |
EP2338510A1 (en) * | 2002-07-19 | 2011-06-29 | Novartis Pharma AG | Vaccine compositions containing amyloid beta1-6 antigen arrays |
ES2424229T3 (es) * | 2005-03-18 | 2013-09-30 | Cytos Biotechnology Ag | Proteínas de fusión de alérgenos de gato y utilización de las mismas |
US20070184068A1 (en) * | 2005-12-14 | 2007-08-09 | Cytos Biotechnology Ag | Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity |
WO2007113633A2 (en) * | 2006-04-03 | 2007-10-11 | Pfizer Products Inc. | Immunogenic compositions comprising cat allergen fel dl |
AT503690A1 (de) * | 2006-06-09 | 2007-12-15 | Biomay Ag | Hypoallergene moleküle |
PL2032592T3 (pl) | 2006-06-12 | 2013-11-29 | Kuros Biosciences Ag | Sposoby pakowania oligonukleotydów do cząstek wirusopodobnych z bakteriofagów RNA |
DK2601969T3 (en) | 2006-09-29 | 2016-04-18 | Takeda Vaccines Inc | Norovirus vaccine formulations |
RU2491937C2 (ru) * | 2007-07-09 | 2013-09-10 | Нестек С.А. | Способы уменьшения аллергических реакций, вызванных аллергенами окружающей среды |
US9388236B2 (en) | 2007-07-09 | 2016-07-12 | Nestec Sa | Methods for reducing allergies caused by environmental allergens |
US20100266636A1 (en) | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
CN104740624B (zh) | 2007-09-18 | 2018-04-24 | 武田疫苗股份有限公司 | 赋予针对诺如病毒的保护性免疫应答的疫苗 |
EP2042193A1 (en) * | 2007-09-28 | 2009-04-01 | Biomay AG | RNA Vaccines |
PL2324113T3 (pl) | 2008-08-08 | 2018-08-31 | Takeda Vaccines, Inc. | Cząstki wirusopodobne zawierające złożone kapsydowe sekwencje aminokwasowe do zwiększonej reaktywności krzyżowej |
BR112013011069A2 (pt) * | 2009-11-05 | 2017-03-28 | Padgett Hal | geração de partículas antigênicas semelhantes a virus através de ligações de proteína-proteína |
US8321012B2 (en) * | 2009-12-22 | 2012-11-27 | The Invention Science Fund I, Llc | Device, method, and system for neural modulation as vaccine adjuvant in a vertebrate subject |
PL3299030T3 (pl) | 2011-07-11 | 2022-12-05 | Takeda Vaccines, Inc. | Pozajelitowe preparaty szczepionek przeciw norowirusowi |
BR112014013035A2 (pt) | 2011-12-22 | 2018-10-09 | Hoffmann La Roche | métodos de seleção de células, conjuntos de expressão bicistrônica, células eucarióticas, vetores lentivirais, uso de vetor lentiviral, bibliotecas de ventores lentivirais e de células eucarióticas, métodos de seleção de células, fluxos de trabalho e uso de célula |
JO3820B1 (ar) | 2012-05-03 | 2021-01-31 | Regeneron Pharma | أجسام مضادة بشرية لـ fel d1وطرق لاستخدامها |
EP2912069B1 (en) * | 2012-10-23 | 2019-07-31 | Emory University | Gm-csf and il-4 conjugates, compositions, and methods related thereto |
EP3564671B1 (en) | 2013-08-23 | 2021-09-29 | Regeneron Pharmaceuticals, Inc. | Diagnostic tests and methods for assessing safety, efficacy or outcome of allergen-specific immunotherapy (sit) |
CN105873603A (zh) | 2013-12-19 | 2016-08-17 | 雀巢产品技术援助有限公司 | 用于减少环境中猫变应原的组合物和方法 |
MA40824A (fr) * | 2014-10-22 | 2017-08-29 | Saiba Gmbh | Particules de cmv de type virus modifié |
EA035378B1 (ru) | 2015-01-15 | 2020-06-04 | Юниверсити Оф Копенгаген | Вирусоподобная частица с эффективным экспонированием эпитопов |
WO2016192788A1 (en) * | 2015-06-03 | 2016-12-08 | Universität Zürich Prorektorat Mnw | Methods and compositions for preventing and treating cat or dog dander allergy |
RU2018105007A (ru) | 2015-09-08 | 2019-10-10 | Университет Цюрих | Композиции против аллергии на кошек |
US11129882B2 (en) | 2015-10-30 | 2021-09-28 | University Of Copenhagen | Virus like particle with efficient epitope display |
CN105219742A (zh) * | 2015-11-10 | 2016-01-06 | 海南大学 | 一种展示重组猫致敏原rFel d 1蛋白的免疫增强型病毒样颗粒、其表达载体及其制备与应用 |
WO2017179025A1 (en) | 2016-04-15 | 2017-10-19 | Alk-Abelló A/S | Epitope polypeptides of ragweed pollen allergens |
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ES2424229T3 (es) * | 2005-03-18 | 2013-09-30 | Cytos Biotechnology Ag | Proteínas de fusión de alérgenos de gato y utilización de las mismas |
-
2006
- 2006-03-17 ES ES06725140T patent/ES2424229T3/es active Active
- 2006-03-17 DK DK06725140.5T patent/DK1868642T3/da active
- 2006-03-17 KR KR1020077022225A patent/KR20070112225A/ko not_active Application Discontinuation
- 2006-03-17 MX MX2007011160A patent/MX2007011160A/es active IP Right Grant
- 2006-03-17 EP EP06725140.5A patent/EP1868642B1/en not_active Not-in-force
- 2006-03-17 RU RU2007138265/15A patent/RU2414239C2/ru not_active IP Right Cessation
- 2006-03-17 CN CN2013101152149A patent/CN103203016A/zh active Pending
- 2006-03-17 JP JP2008501331A patent/JP5302671B2/ja not_active Expired - Fee Related
- 2006-03-17 CN CN2006800088726A patent/CN101141979B/zh not_active Expired - Fee Related
- 2006-03-17 AU AU2006224529A patent/AU2006224529B2/en not_active Ceased
- 2006-03-17 US US11/886,577 patent/US7767212B2/en not_active Expired - Fee Related
- 2006-03-17 PL PL06725140T patent/PL1868642T3/pl unknown
- 2006-03-17 BR BRPI0608455-9A patent/BRPI0608455A2/pt active Search and Examination
- 2006-03-17 ZA ZA200707413A patent/ZA200707413B/xx unknown
- 2006-03-17 WO PCT/EP2006/060845 patent/WO2006097530A2/en active Application Filing
- 2006-03-17 CA CA2599218A patent/CA2599218C/en not_active Expired - Fee Related
- 2006-03-17 NZ NZ561040A patent/NZ561040A/en not_active IP Right Cessation
- 2006-03-17 PT PT67251405T patent/PT1868642E/pt unknown
-
2007
- 2007-08-07 IL IL185103A patent/IL185103A0/en not_active IP Right Cessation
-
2010
- 2010-05-21 US US12/785,174 patent/US20110045013A1/en not_active Abandoned
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2012
- 2012-12-21 US US13/724,331 patent/US20130344098A1/en not_active Abandoned
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2013
- 2013-03-12 JP JP2013048847A patent/JP2013155176A/ja active Pending
- 2013-07-26 CY CY20131100638T patent/CY1114171T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO2006097530A2 (en) | 2006-09-21 |
CN103203016A (zh) | 2013-07-17 |
PT1868642E (pt) | 2013-07-10 |
RU2007138265A (ru) | 2009-04-27 |
CN101141979A (zh) | 2008-03-12 |
PL1868642T3 (pl) | 2013-10-31 |
IL185103A0 (en) | 2007-12-03 |
RU2414239C2 (ru) | 2011-03-20 |
US20090175896A1 (en) | 2009-07-09 |
JP2013155176A (ja) | 2013-08-15 |
JP2008535800A (ja) | 2008-09-04 |
US20110045013A1 (en) | 2011-02-24 |
US20130344098A1 (en) | 2013-12-26 |
WO2006097530A3 (en) | 2007-06-21 |
CA2599218A1 (en) | 2006-09-21 |
AU2006224529B2 (en) | 2012-05-24 |
EP1868642A2 (en) | 2007-12-26 |
US7767212B2 (en) | 2010-08-03 |
BRPI0608455A2 (pt) | 2010-01-05 |
EP1868642B1 (en) | 2013-05-08 |
ES2424229T3 (es) | 2013-09-30 |
KR20070112225A (ko) | 2007-11-22 |
CA2599218C (en) | 2015-08-11 |
DK1868642T3 (da) | 2013-06-24 |
ZA200707413B (en) | 2009-01-28 |
CN101141979B (zh) | 2013-05-08 |
AU2006224529A1 (en) | 2006-09-21 |
NZ561040A (en) | 2009-04-30 |
MX2007011160A (es) | 2007-11-13 |
JP5302671B2 (ja) | 2013-10-02 |
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