CY1112561T1 - Φαρμοκολογικη λυση του υαλοειδους, με τη χρηση κολουρης πλασμινης - Google Patents

Φαρμοκολογικη λυση του υαλοειδους, με τη χρηση κολουρης πλασμινης

Info

Publication number
CY1112561T1
CY1112561T1 CY20121100179T CY121100179T CY1112561T1 CY 1112561 T1 CY1112561 T1 CY 1112561T1 CY 20121100179 T CY20121100179 T CY 20121100179T CY 121100179 T CY121100179 T CY 121100179T CY 1112561 T1 CY1112561 T1 CY 1112561T1
Authority
CY
Cyprus
Prior art keywords
eye
vitreous
plasmin
reduce
color
Prior art date
Application number
CY20121100179T
Other languages
Greek (el)
English (en)
Inventor
Steve Pakola
Smet Marc De
Original Assignee
Thrombogenics N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thrombogenics N.V. filed Critical Thrombogenics N.V.
Publication of CY1112561T1 publication Critical patent/CY1112561T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/484Plasmin (3.4.21.7)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01023Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01035Hyaluronoglucosaminidase (3.2.1.35), i.e. hyaluronidase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21007Plasmin (3.4.21.7), i.e. fibrinolysin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24Metalloendopeptidases (3.4.24)
    • C12Y304/24007Interstitial collagenase (3.4.24.7), i.e. matrix metalloprotease 1 or MMP1
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/02Carbon-oxygen lyases (4.2) acting on polysaccharides (4.2.2)
    • C12Y402/02004Chondroitin ABC lyase (4.2.2.4), i.e. chondroitinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/02Carbon-oxygen lyases (4.2) acting on polysaccharides (4.2.2)
    • C12Y402/02005Chondroitin AC lyase (4.2.2.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y402/00Carbon-oxygen lyases (4.2)
    • C12Y402/02Carbon-oxygen lyases (4.2) acting on polysaccharides (4.2.2)
    • C12Y402/02019Chondroitin B lyase (4.2.2.19)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Inorganic Insulating Materials (AREA)
CY20121100179T 2002-12-06 2012-02-21 Φαρμοκολογικη λυση του υαλοειδους, με τη χρηση κολουρης πλασμινης CY1112561T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0228409.9A GB0228409D0 (en) 2002-12-06 2002-12-06 Pharmacological vitreolysis
EP03812818A EP1581254B1 (fr) 2002-12-06 2003-12-05 Vitreolyse pharmacologique en utilisant une plasmine raccourci

Publications (1)

Publication Number Publication Date
CY1112561T1 true CY1112561T1 (el) 2015-11-04

Family

ID=9949140

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20121100179T CY1112561T1 (el) 2002-12-06 2012-02-21 Φαρμοκολογικη λυση του υαλοειδους, με τη χρηση κολουρης πλασμινης
CY2013033C CY2013033I2 (el) 2002-12-06 2013-08-23 Φαρμοκολογικη λυση του υαλοειδους, με τη χρηση κολουρης πλασμινης

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY2013033C CY2013033I2 (el) 2002-12-06 2013-08-23 Φαρμοκολογικη λυση του υαλοειδους, με τη χρηση κολουρης πλασμινης

Country Status (25)

Country Link
US (11) US7547435B2 (fr)
EP (3) EP2327416B1 (fr)
JP (4) JP5426063B2 (fr)
CN (1) CN100577202C (fr)
AT (1) ATE534400T1 (fr)
AU (1) AU2003300821C1 (fr)
BE (1) BE2013C055I2 (fr)
BR (2) BRPI0310144A8 (fr)
CA (1) CA2508606C (fr)
CY (2) CY1112561T1 (fr)
DK (1) DK1581254T3 (fr)
ES (2) ES2377965T3 (fr)
FR (1) FR13C0052I2 (fr)
GB (1) GB0228409D0 (fr)
HK (1) HK1082419A1 (fr)
HU (1) HUS1300040I1 (fr)
IL (3) IL169008A (fr)
LU (1) LU92273I2 (fr)
MX (1) MXPA05006038A (fr)
NO (4) NO333837B1 (fr)
NZ (1) NZ541075A (fr)
PT (2) PT2327416T (fr)
SI (1) SI1581254T1 (fr)
WO (1) WO2004052228A2 (fr)
ZA (1) ZA200505193B (fr)

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Also Published As

Publication number Publication date
JP5451533B2 (ja) 2014-03-26
NO343759B1 (no) 2019-06-03
EP1581254A4 (fr) 2007-03-28
CN1738641A (zh) 2006-02-22
CY2013033I1 (el) 2015-11-04
NO333837B1 (no) 2013-09-30
US9770494B2 (en) 2017-09-26
LU92273I2 (fr) 2013-10-29
EP2327416A1 (fr) 2011-06-01
AU2003300821B2 (en) 2009-07-09
SI1581254T1 (sl) 2012-05-31
JP2013241448A (ja) 2013-12-05
US7867489B2 (en) 2011-01-11
LU92273I9 (fr) 2019-01-15
NO2013016I2 (no) 2017-06-28
CN100577202C (zh) 2010-01-06
US8383105B2 (en) 2013-02-26
EP2327415B1 (fr) 2017-10-18
IL213838A0 (en) 2011-07-31
AU2003300821A1 (en) 2004-06-30
WO2004052228A2 (fr) 2004-06-24
US7914783B2 (en) 2011-03-29
GB0228409D0 (en) 2003-01-08
AU2003300821C1 (en) 2012-03-22
CA2508606A1 (fr) 2004-06-24
US20080095753A1 (en) 2008-04-24
PT2327416T (pt) 2019-07-04
NO20121169A1 (no) 2012-10-12
BE2013C055I2 (fr) 2023-03-07
IL202851A (en) 2015-04-30
WO2004052228A3 (fr) 2004-10-07
BR0317033A (pt) 2005-10-25
EP1581254A2 (fr) 2005-10-05
FR13C0052I2 (fr) 2014-11-21
US20110171190A1 (en) 2011-07-14
CA2508606C (fr) 2015-07-28
NO20121170A1 (no) 2012-10-12
JP2015131842A (ja) 2015-07-23
NO20052988D0 (no) 2005-06-17
DK1581254T3 (da) 2012-02-27
US20050118158A1 (en) 2005-06-02
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US7547435B2 (en) 2009-06-16
US20150064161A1 (en) 2015-03-05
US20130195887A1 (en) 2013-08-01
HK1082419A1 (en) 2006-06-09
US7803368B2 (en) 2010-09-28
US20110300123A1 (en) 2011-12-08
US8834869B2 (en) 2014-09-16
BRPI0310144A8 (pt) 2018-04-24
ZA200505193B (en) 2007-08-29
JP2010222369A (ja) 2010-10-07
US20080050356A1 (en) 2008-02-28
PT1581254E (pt) 2012-02-06
CY2013033I2 (el) 2015-11-04
US8460655B2 (en) 2013-06-11
ES2731625T3 (es) 2019-11-18
EP2327416B1 (fr) 2019-05-01
JP2006518708A (ja) 2006-08-17
JP5426063B2 (ja) 2014-02-26
EP2327415A1 (fr) 2011-06-01
FR13C0052I1 (fr) 2013-04-10
EP1581254B1 (fr) 2011-11-23
HUS1300040I1 (hu) 2013-08-15
IL169008A (en) 2011-08-31
ES2377965T3 (es) 2012-04-03
NO2013016I1 (no) 2013-11-19
JP5739487B2 (ja) 2015-06-24
NO20052988L (no) 2005-09-05
IL202851A0 (en) 2011-07-31
ATE534400T1 (de) 2011-12-15
US20090074739A1 (en) 2009-03-19
US20130302304A1 (en) 2013-11-14
NZ541075A (en) 2008-02-29
US9186394B2 (en) 2015-11-17
US20130202613A1 (en) 2013-08-08
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US20090081187A1 (en) 2009-03-26
US8747842B2 (en) 2014-06-10

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