CY1110309T1 - Φαρμακευτικες συνθεσεις για την προληψη και την αγωγη διαταραχων του κεντρικου νευρικου συστηματος περιλαμβανοντας ενα αναλογο νικοτινης και εναν αναστολεα ακετυλχολινεστερασης - Google Patents
Φαρμακευτικες συνθεσεις για την προληψη και την αγωγη διαταραχων του κεντρικου νευρικου συστηματος περιλαμβανοντας ενα αναλογο νικοτινης και εναν αναστολεα ακετυλχολινεστερασηςInfo
- Publication number
- CY1110309T1 CY1110309T1 CY20091100150T CY091100150T CY1110309T1 CY 1110309 T1 CY1110309 T1 CY 1110309T1 CY 20091100150 T CY20091100150 T CY 20091100150T CY 091100150 T CY091100150 T CY 091100150T CY 1110309 T1 CY1110309 T1 CY 1110309T1
- Authority
- CY
- Cyprus
- Prior art keywords
- nicotinic
- trafficking
- analogue
- prevention
- pharmaceutical compositions
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Μια φαρμακευτική σύνθεση ενσωματώνει μια φαρμακευτικώς αποτελεσματική ποσότητα δύο τουλάχιστον συστατικών, ένα εξ εκείνων των συστατικών όντας μια νικοτινική ένωση δυνάμενη αλληλεπίδρασης με νικοτινικούς χολινεργικούς υποδοχείς (π.χ., έναν νικοτινικό αγωνιστή όπως είναι η Ε-μετανικοτίνη) και ένα εξ εκείνων των συστατικών όντας ένας αναστολέας ακετυλχολινεστεράσης (π.χ., η τακρίνη). Η φαρμακευτική σύνθεση είναι χρήσιμη για την αγωγή διαταραχών του ΚΝΣ, όπως είναι η νόσος του Αλζχάϊμερ.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/130,498 US6218383B1 (en) | 1998-08-07 | 1998-08-07 | Pharmaceutical compositions for the prevention and treatment of central nervous system disorders |
EP99965348A EP1102588B1 (en) | 1998-08-07 | 1999-06-02 | Pharmaceutical compositions for the prevention and treatment of central nervous system disorders comprising a nicotine analog and an acetylcholinesterase inhibitor |
Publications (1)
Publication Number | Publication Date |
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CY1110309T1 true CY1110309T1 (el) | 2015-01-14 |
Family
ID=22444976
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20091100150T CY1110309T1 (el) | 1998-08-07 | 2009-02-10 | Φαρμακευτικες συνθεσεις για την προληψη και την αγωγη διαταραχων του κεντρικου νευρικου συστηματος περιλαμβανοντας ενα αναλογο νικοτινης και εναν αναστολεα ακετυλχολινεστερασης |
CY20141100777T CY1115589T1 (el) | 1998-08-07 | 2014-09-24 | Φαρμακευτικες συνθεσεις για την προληψη και αγωγη των διαταραχων του κεντρικου νευρικου συστηματος περιλαμβανοντας μια νικοτινικη ενωση και εναν αναστολεα ακετυλχολινεστερασης |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20141100777T CY1115589T1 (el) | 1998-08-07 | 2014-09-24 | Φαρμακευτικες συνθεσεις για την προληψη και αγωγη των διαταραχων του κεντρικου νευρικου συστηματος περιλαμβανοντας μια νικοτινικη ενωση και εναν αναστολεα ακετυλχολινεστερασης |
Country Status (16)
Country | Link |
---|---|
US (1) | US6218383B1 (el) |
EP (2) | EP2018874B1 (el) |
JP (2) | JP4750945B2 (el) |
KR (1) | KR100705434B1 (el) |
AT (1) | ATE418986T1 (el) |
AU (1) | AU761087B2 (el) |
BR (1) | BR9912805A (el) |
CA (1) | CA2335012C (el) |
CY (2) | CY1110309T1 (el) |
DE (1) | DE69940199D1 (el) |
DK (2) | DK2018874T3 (el) |
ES (2) | ES2515120T3 (el) |
HK (1) | HK1127290A1 (el) |
MX (1) | MXPA01001435A (el) |
PT (2) | PT2018874E (el) |
WO (1) | WO2000007600A1 (el) |
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-
1998
- 1998-08-07 US US09/130,498 patent/US6218383B1/en not_active Expired - Lifetime
-
1999
- 1999-06-02 PT PT80199144T patent/PT2018874E/pt unknown
- 1999-06-02 ES ES08019914.4T patent/ES2515120T3/es not_active Expired - Lifetime
- 1999-06-02 EP EP08019914.4A patent/EP2018874B1/en not_active Expired - Lifetime
- 1999-06-02 WO PCT/US1999/012243 patent/WO2000007600A1/en not_active Application Discontinuation
- 1999-06-02 JP JP2000563285A patent/JP4750945B2/ja not_active Expired - Fee Related
- 1999-06-02 CA CA002335012A patent/CA2335012C/en not_active Expired - Fee Related
- 1999-06-02 KR KR1020007014515A patent/KR100705434B1/ko not_active IP Right Cessation
- 1999-06-02 BR BR9912805-5A patent/BR9912805A/pt not_active Application Discontinuation
- 1999-06-02 ES ES99965348T patent/ES2322725T3/es not_active Expired - Lifetime
- 1999-06-02 DE DE69940199T patent/DE69940199D1/de not_active Expired - Lifetime
- 1999-06-02 MX MXPA01001435A patent/MXPA01001435A/es not_active IP Right Cessation
- 1999-06-02 AT AT99965348T patent/ATE418986T1/de active
- 1999-06-02 EP EP99965348A patent/EP1102588B1/en not_active Expired - Lifetime
- 1999-06-02 DK DK08019914.4T patent/DK2018874T3/da active
- 1999-06-02 AU AU43285/99A patent/AU761087B2/en not_active Ceased
- 1999-06-02 DK DK99965348T patent/DK1102588T3/da active
- 1999-06-02 PT PT99965348T patent/PT1102588E/pt unknown
-
2009
- 2009-02-10 CY CY20091100150T patent/CY1110309T1/el unknown
- 2009-06-25 HK HK09105736.9A patent/HK1127290A1/xx not_active IP Right Cessation
-
2011
- 2011-02-24 JP JP2011038189A patent/JP2011137027A/ja active Pending
-
2014
- 2014-09-24 CY CY20141100777T patent/CY1115589T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2322725T3 (es) | 2009-06-25 |
JP4750945B2 (ja) | 2011-08-17 |
CA2335012A1 (en) | 2000-02-17 |
US6218383B1 (en) | 2001-04-17 |
CY1115589T1 (el) | 2017-01-04 |
WO2000007600A1 (en) | 2000-02-17 |
EP1102588B1 (en) | 2008-12-31 |
EP2018874A3 (en) | 2012-11-21 |
DK1102588T3 (da) | 2009-04-14 |
JP2011137027A (ja) | 2011-07-14 |
BR9912805A (pt) | 2001-05-02 |
EP2018874A2 (en) | 2009-01-28 |
AU761087B2 (en) | 2003-05-29 |
PT1102588E (pt) | 2009-02-26 |
ES2515120T3 (es) | 2014-10-29 |
ATE418986T1 (de) | 2009-01-15 |
HK1127290A1 (en) | 2009-09-25 |
EP2018874B1 (en) | 2014-08-13 |
AU4328599A (en) | 2000-02-28 |
JP2002522390A (ja) | 2002-07-23 |
MXPA01001435A (es) | 2003-09-10 |
KR100705434B1 (ko) | 2007-04-09 |
DK2018874T3 (da) | 2014-10-13 |
EP1102588A1 (en) | 2001-05-30 |
CA2335012C (en) | 2009-08-11 |
PT2018874E (pt) | 2014-10-16 |
DE69940199D1 (de) | 2009-02-12 |
KR20010072631A (ko) | 2001-07-31 |
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