CY1108861T1 - Μεθοδος δια την παρασκευη παραγωγων 4-(ιμιδαζολ-1-υλ)-βενζολοσουλφοναμιδης - Google Patents

Μεθοδος δια την παρασκευη παραγωγων 4-(ιμιδαζολ-1-υλ)-βενζολοσουλφοναμιδης

Info

Publication number
CY1108861T1
CY1108861T1 CY20081100892T CY081100892T CY1108861T1 CY 1108861 T1 CY1108861 T1 CY 1108861T1 CY 20081100892 T CY20081100892 T CY 20081100892T CY 081100892 T CY081100892 T CY 081100892T CY 1108861 T1 CY1108861 T1 CY 1108861T1
Authority
CY
Cyprus
Prior art keywords
imidazol
preparation
formula
benzolosulfonamidis
producers
Prior art date
Application number
CY20081100892T
Other languages
English (en)
Inventor
Rosales Carmen Almansa
Gonzalez Concepcion Gonzalez
Original Assignee
Palau Pharma, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Palau Pharma, S.A. filed Critical Palau Pharma, S.A.
Publication of CY1108861T1 publication Critical patent/CY1108861T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
    • C07C311/39—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/40—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms

Abstract

Μέθοδος δια την παρασκευή παραγώγων 4- (ιμιδαζολ -1 -υλ) βενζολοσουλφοναμίδης του τύπου I, όπου το R1 παριστά ενδεχομένως υποκατεστημένο αρύλ ή ετεροαρύλ, το οποίον περιλαμβάνει κατεργασία μιας ενώσεως του τύπου II, όπου το R1 έχει την ιδία σημασία που ορίσθη εις τον τύπο I και το But παριστά τριτ-βουτύλ, με ένα οξύ. Τα παράγωγα 4- (ιμιδαζόλ-1- υλ) βενζολοσουλφοναμίδης του τύπου I είναι χρήσιμα ως αντιφλογιστικοί παράγοντες.
CY20081100892T 2001-08-07 2008-08-21 Μεθοδος δια την παρασκευη παραγωγων 4-(ιμιδαζολ-1-υλ)-βενζολοσουλφοναμιδης CY1108861T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200101853A ES2184633B1 (es) 2001-08-07 2001-08-07 Procedimiento para la preparacion de derivados de 4-(imidazol-1-il) bencenosulfonamida.
EP02794802A EP1424329B1 (en) 2001-08-07 2002-08-01 Process for the preparation of 4-(imidazol-1-yl)benzenesulfonamide derivatives

Publications (1)

Publication Number Publication Date
CY1108861T1 true CY1108861T1 (el) 2014-08-13

Family

ID=8498662

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081100892T CY1108861T1 (el) 2001-08-07 2008-08-21 Μεθοδος δια την παρασκευη παραγωγων 4-(ιμιδαζολ-1-υλ)-βενζολοσουλφοναμιδης

Country Status (17)

Country Link
US (2) US7351836B2 (el)
EP (1) EP1424329B1 (el)
JP (1) JP4309262B2 (el)
KR (1) KR100888905B1 (el)
AR (2) AR037231A1 (el)
AT (1) ATE396976T1 (el)
BR (1) BRPI0211749B8 (el)
CA (1) CA2456531C (el)
CY (1) CY1108861T1 (el)
DE (1) DE60226879D1 (el)
DK (1) DK1424329T3 (el)
ES (2) ES2184633B1 (el)
HK (1) HK1066214A1 (el)
MX (1) MXPA04001147A (el)
NO (1) NO326162B1 (el)
PT (1) PT1424329E (el)
WO (1) WO2003016285A1 (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2015DN00202A (el) 2012-07-12 2015-06-12 Chiesi Farma Spa
WO2022269384A1 (en) * 2021-06-24 2022-12-29 Ami Organics Ltd. A process for the direct synthesis of fedratinib intermediate

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TNSN99111A1 (fr) * 1998-06-11 2005-11-10 Pfizer Derives de sulfonylbenzene nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant.
DE69935913T2 (de) * 1998-07-02 2008-01-10 Cryptography Research Inc., San Francisco Leckresistente aktualisierung eines indexierten kryptographischen schlüssels
AR024222A1 (es) * 1998-10-16 2002-09-25 Palau Pharma Sa Imidazoles con actividad antiinflamatoria un procedimiento para su preparacion y composiciones farmaceuticas que lo contienen
ES2159489B1 (es) 2000-03-23 2002-04-16 Uriach & Cia Sa J Nuevos derivados de imidazol con actividad antiinflamatoria.

Also Published As

Publication number Publication date
AR086065A2 (es) 2013-11-13
KR20040020079A (ko) 2004-03-06
ES2184633A1 (es) 2003-04-01
US8476456B2 (en) 2013-07-02
MXPA04001147A (es) 2004-07-08
AR037231A1 (es) 2004-11-03
ES2307817T3 (es) 2008-12-01
JP2005502659A (ja) 2005-01-27
NO326162B1 (no) 2008-10-13
KR100888905B1 (ko) 2009-03-16
CA2456531A1 (en) 2003-02-27
BR0211749B1 (pt) 2013-09-10
DE60226879D1 (de) 2008-07-10
WO2003016285A8 (es) 2003-08-28
ATE396976T1 (de) 2008-06-15
EP1424329A1 (en) 2004-06-02
WO2003016285A1 (es) 2003-02-27
EP1424329B1 (en) 2008-05-28
US7351836B2 (en) 2008-04-01
BR0211749A (pt) 2004-10-13
US20090012307A1 (en) 2009-01-08
HK1066214A1 (en) 2005-03-18
NO20040981L (no) 2004-03-05
ES2184633B1 (es) 2004-08-01
BRPI0211749B8 (pt) 2021-05-25
DK1424329T3 (da) 2008-09-29
CA2456531C (en) 2010-12-14
JP4309262B2 (ja) 2009-08-05
PT1424329E (pt) 2008-08-06
US20040242872A1 (en) 2004-12-02

Similar Documents

Publication Publication Date Title
CY1105797T1 (el) Ν-αρυλ-2-οχαζολιδινονο-5-καρβοξαμιδια και παραγωγα αυτων και χρηση αυτων σαν αντιβιοτικα
CY1109886T1 (el) Καινοφανεις ενωσεις ως αντι-φλεγμονωδεις, ανοσοτροποποιητικοι και αντι υπερπλαστικοι παραγοντες
BR9900177A (pt) Inibidores de metaloprotease.
CY1108254T1 (el) Ενωσεις που επηρεαζουν τη γλυκοκιναση
CY1110434T1 (el) Παραγωγα ν-πυρρολιδιν-3-υλ-αμιδιου ως αναστολεις επαναπροσληψεως σεροτονινης και νοραδρεναλινης
CY1111425T1 (el) ΠΑΡΑΓΩΓΑ ΤΗΣ ΠΥΡΙΔΟ[2,1-a]-ΙΣΟΚΙΝΟΛΙΝΗΣ ΩΣ DPP-IV ΑΝΑΣΤΟΛΕΙΣ
CY1108707T1 (el) Αναλογα νοσισεπτινης
CY1105047T1 (el) Ενωσεις πυριδοπυριμιδινονης, η μεθοδος παρασκευης τους και φαρμακευτικες συνθεσεις που τις περιεχουν
CY1113487T1 (el) Νεα παραγωγα μανδελικου οξεος και η χρηση τους ως αναστολεις θροβινης
BR9910326A (pt) Processo para preeparar isoxazóis, composto, processo para preparar compostos, uso de compostos, e, processo para preparar tioéteres
CY1106003T1 (el) Παραγωγα του ν-βενζοϋλοουρεϊδο-κινναμωμικου οξεος, μεθοδος για την παρασκευη τους και η χρηση τους
CY1110539T1 (el) Μεθοδος για παραγωγα φαινυλοξικου οξεος
CY1106343T1 (el) Παραγωγα νικοτιναμιδιου χρησιμα σαν pde4 αναστολεις
CY1108848T1 (el) Εντομοκτονες ανθρανιλαμιδες
CY1108183T1 (el) Θειαζολυλο-διυδρο-ινδαζολια
CY1105423T1 (el) Παραγωγα ιμιδαζολης μεθοδος παραγωγης και χρηση αυτων
DK1295890T3 (da) Hidtil ukendte pyrazinderivater eller salte deraf, farmaceutiske præparater, der indeholder derivaterne eller saltene, og mellemprodukter til fremstilling af begge
CY1107149T1 (el) Νεα παραγωγα αμιδινοβενζυλαμινης και χρηση τους ως αναστολεων θρομβινης
CY1109300T1 (el) Νεοι συντηγμενοι ετεροκυκλικοι δακτυλιοι και χρησεις αυτων
EA200000826A1 (ru) Галоидированные производные амидиноаминокислот, применимые в качестве ингибиторов no-синтазы
CY1113171T1 (el) Αντιφλεγμονωδεις παραγοντες
CY1123488T1 (el) Πεντακυκλοθειενυλο και ινδανυλο παραγωγα ουριας ως παραγοντες διανοιξης διαυλου καλιου
DE60116589D1 (de) Fungizide Phenylamidinderivative
CY1106993T1 (el) Παραγωγα αζολινης
DK1706414T3 (da) Fremgangsmåde til fluorcytidinderivater