CY1108303T1 - Η χρηση μιας ενωσης ινγκενανης για την κατασκευη ενος φαρμακου για την θεραπεια του καρκινου - Google Patents

Η χρηση μιας ενωσης ινγκενανης για την κατασκευη ενος φαρμακου για την θεραπεια του καρκινου

Info

Publication number
CY1108303T1
CY1108303T1 CY20081100929T CY081100929T CY1108303T1 CY 1108303 T1 CY1108303 T1 CY 1108303T1 CY 20081100929 T CY20081100929 T CY 20081100929T CY 081100929 T CY081100929 T CY 081100929T CY 1108303 T1 CY1108303 T1 CY 1108303T1
Authority
CY
Cyprus
Prior art keywords
compounds
euphorbia
plants
compound
group
Prior art date
Application number
CY20081100929T
Other languages
English (en)
Inventor
James Harrison Aylward
Original Assignee
Peplin Research Pty Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3802927&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1108303(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Peplin Research Pty Ltd. filed Critical Peplin Research Pty Ltd.
Publication of CY1108303T1 publication Critical patent/CY1108303T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Emergency Medicine (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Αυτή η εφεύρεση αναφέρεται σε μία ένωση ή ομάδα ενώσεων παρουσών σε μία δραστική κύρια ουσία προερχόμενη από τα φυτά του είδους Euphorbia peplus, Euphorbia hirta και Euphorbia drummondii, και σε φαρμακευτικές συνθέσεις που περιλαμβάνουν αυτές τις ενώσεις. Τα εκχυλίσματα απ' αυτά τα φυτά έχει διαπιστωθεί ότι παρουσιάζουν επιλεκτική κυτταροτοξικότητα ενάντια σε αρκετές διαφορετικές καρκινικές κυτταρικές γραμμές. Οι ενώσεις είναι χρήσιμες στην αποτελεσματική θεραπεία των καρκίνων, ιδιαίτερα των κακοήθων μελανωμάτων και των καρκινωμάτων των λεπιδωδών κυττάρων (SCCs). Σε μια προτιμώμενη ενσωμάτωση της εφεύρεσης, η ένωση επιλέγεται από την ομάδα που αποτελείται από τις γιατροφάνες, τις πεπλουάνες, τις παραλιάνες και τις ινγκενάνες, και τα φαρμακευτικά αποδεκτά άλατα ή τους εστέρες τους, και ειδικότερα τις γιατροφάνες Συμμόρφωσης II.
CY20081100929T 1997-08-19 2008-08-29 Η χρηση μιας ενωσης ινγκενανης για την κατασκευη ενος φαρμακου για την θεραπεια του καρκινου CY1108303T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPO8640A AUPO864097A0 (en) 1997-08-19 1997-08-19 Anti-cancer compounds
EP98938534A EP1015413B1 (en) 1997-08-19 1998-08-19 Use of an ingenane compound for the manufacture of a medicament for the treatment of cancer

Publications (1)

Publication Number Publication Date
CY1108303T1 true CY1108303T1 (el) 2014-02-12

Family

ID=3802927

Family Applications (2)

Application Number Title Priority Date Filing Date
CY20081100929T CY1108303T1 (el) 1997-08-19 2008-08-29 Η χρηση μιας ενωσης ινγκενανης για την κατασκευη ενος φαρμακου για την θεραπεια του καρκινου
CY2013020C CY2013020I1 (el) 1997-08-19 2013-05-13 Η χρηση μιας ενωσης ινγκενανης για την κατασκευη ενος φαρμακου για την θεραπεια του καρκινου

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY2013020C CY2013020I1 (el) 1997-08-19 2013-05-13 Η χρηση μιας ενωσης ινγκενανης για την κατασκευη ενος φαρμακου για την θεραπεια του καρκινου

Country Status (17)

Country Link
US (4) US6432452B1 (el)
EP (1) EP1015413B1 (el)
JP (3) JP2001515059A (el)
CN (1) CN1266421B (el)
AT (1) ATE397580T1 (el)
AU (1) AUPO864097A0 (el)
BE (1) BE2013C026I2 (el)
BR (1) BR9811327A (el)
CA (1) CA2301082C (el)
CY (2) CY1108303T1 (el)
DE (1) DE69839586D1 (el)
DK (1) DK1015413T3 (el)
ES (1) ES2308810T3 (el)
HU (2) HU228862B1 (el)
LU (1) LU92185I2 (el)
PT (1) PT1015413E (el)
WO (1) WO1999008994A1 (el)

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Also Published As

Publication number Publication date
CN1266421B (zh) 2014-06-18
AU8721798A (en) 1999-03-08
JP2012031212A (ja) 2012-02-16
BE2013C026I2 (en) 2018-06-05
HUP0004262A1 (hu) 2001-08-28
LU92185I2 (fr) 2014-04-23
HU228862B1 (en) 2013-06-28
ES2308810T3 (es) 2008-12-01
DE69839586D1 (de) 2008-07-17
BR9811327A (pt) 2000-09-19
CY2013020I2 (el) 2019-11-27
WO1999008994A1 (en) 1999-02-25
US6787161B2 (en) 2004-09-07
AUPO864097A0 (en) 1997-09-11
DK1015413T3 (da) 2008-09-22
US6844013B2 (en) 2005-01-18
ATE397580T1 (de) 2008-06-15
US20050003031A1 (en) 2005-01-06
US7410656B2 (en) 2008-08-12
CY2013020I1 (el) 2019-11-27
US20020076457A1 (en) 2002-06-20
US20010051644A1 (en) 2001-12-13
PT1015413E (pt) 2008-09-15
CN1266421A (zh) 2000-09-13
HUS1300063I1 (hu) 2019-11-28
CA2301082C (en) 2009-02-03
JP2015007130A (ja) 2015-01-15
EP1015413B1 (en) 2008-06-04
AU736230B2 (en) 2001-07-26
EP1015413A4 (en) 2004-01-28
CA2301082A1 (en) 1999-02-25
EP1015413A1 (en) 2000-07-05
US6432452B1 (en) 2002-08-13
JP2001515059A (ja) 2001-09-18

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