CY1107271T1 - Μεθοδος για αντιβιοτικη επικαλυψη σωματων με συγκοινωνουσες μικροκοιλοτητες, σωματα επικαλυμμενα με τον τροπο αυτο και χρηση αυτων - Google Patents
Μεθοδος για αντιβιοτικη επικαλυψη σωματων με συγκοινωνουσες μικροκοιλοτητες, σωματα επικαλυμμενα με τον τροπο αυτο και χρηση αυτωνInfo
- Publication number
- CY1107271T1 CY1107271T1 CY081100074T CY081100074T CY1107271T1 CY 1107271 T1 CY1107271 T1 CY 1107271T1 CY 081100074 T CY081100074 T CY 081100074T CY 081100074 T CY081100074 T CY 081100074T CY 1107271 T1 CY1107271 T1 CY 1107271T1
- Authority
- CY
- Cyprus
- Prior art keywords
- gentamycin
- dodekylotheiiki
- tetrakis
- pentakis
- coated
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
- A61L2300/406—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
- A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/249921—Web or sheet containing structurally defined element or component
- Y10T428/249953—Composite having voids in a component [e.g., porous, cellular, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Transplantation (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Saccharide Compounds (AREA)
- Fertilizers (AREA)
- Laminated Bodies (AREA)
Abstract
Η μέθοδος αφορά την παραγωγή επικαλυμμένων με μια αντιβιοτική επικάλυψη σωμάτων με συγκοινωνούσες μικροκοιλότητες, σώματα επικαλυμμένα με τον τρόπο αυτό, καθώς και τη χρήση αυτών. Σε μια προτιμώμενη μορφή υλοποίησης στις μικροκοιλότητες των μη μεταλλικών σωμάτων με διασυνδεδεμένες μικροκοιλότητες, τα οποία αποτελούνται από κολλαγόνο ή ζελατίνη ή πολυεστέρες ή τριφωσφορικό ασβέστιο ή υδροξυαπατίτη, εισάγεται, ένα ομογενές διάλυμα από πεντάκις δωδεκυλοθειική γενταμυκίνη, από τετράκις δωδεκυλοθειική γενταμυκίνη, από πεντάκις δωδεκυλοσουλφονική γενταμυκίνη ή από τετράκις δωδεκυλοσουλφονική γενταμυκίνη, το οποίο περιέχει ως διαλύτη μεθανόλη και/ή αιθανόλη και ή Ν,Ν-διμεθυλοφορμαμίδιο και ή διμεθυλοσουλφοξείδιο, με εμβάπτιση, ψεκασμό και ενστάλαξη και μετά από εξάτμιση ή εξαέρωση του οργανικού διαλύτη σχηματίζει στην επιφάνεια των μικροκοιλοτήτων ένα στρώμα από πεντάκις δωδεκυλοθειική γενταμυκίνη, τετράκις δωδεκυλοθειική γενταμυκίνη, πεντάκις δωδεκυλοσουλφονική γενταμυκίνη ή τετράκις δωδεκυλοσουλφονική γενταμυκίνη.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10142465A DE10142465A1 (de) | 2001-08-31 | 2001-08-31 | Verfahren zur antibiotischen Beschichtung von nichtmetallischen Körpern mit interkonnektierenden Mikrohohlräumen, nichtmetallischer Körper sowie seine Verwendung |
| DE10204307 | 2002-02-01 | ||
| EP20020018322 EP1287818B1 (de) | 2001-08-31 | 2002-08-14 | Verfahren zur antibiotischen Beschichtung von Körpern mit interkonnektierenden Mikrohohlräumen, so beschichtete Körper sowie deren Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1107271T1 true CY1107271T1 (el) | 2012-11-21 |
Family
ID=26010028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY081100074T CY1107271T1 (el) | 2001-08-31 | 2008-01-18 | Μεθοδος για αντιβιοτικη επικαλυψη σωματων με συγκοινωνουσες μικροκοιλοτητες, σωματα επικαλυμμενα με τον τροπο αυτο και χρηση αυτων |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US6984410B2 (el) |
| EP (1) | EP1287818B1 (el) |
| JP (1) | JP3740449B2 (el) |
| CN (1) | CN1203903C (el) |
| AU (1) | AU2002300656B2 (el) |
| BG (1) | BG65774B1 (el) |
| BR (1) | BR0203427A (el) |
| CA (1) | CA2396146C (el) |
| CY (1) | CY1107271T1 (el) |
| CZ (1) | CZ301740B6 (el) |
| DE (1) | DE50211246D1 (el) |
| DK (1) | DK1287818T3 (el) |
| EE (1) | EE200200491A (el) |
| ES (1) | ES2295268T3 (el) |
| GE (1) | GEP20043333B (el) |
| HR (1) | HRP20020680B1 (el) |
| HU (1) | HUP0202916A3 (el) |
| IL (1) | IL150999A0 (el) |
| IS (1) | IS6390A (el) |
| MD (1) | MD2633C2 (el) |
| MX (1) | MXPA02008326A (el) |
| NO (1) | NO20024101L (el) |
| NZ (1) | NZ521043A (el) |
| PL (1) | PL206972B1 (el) |
| PT (1) | PT1287818E (el) |
| RU (1) | RU2236261C2 (el) |
| SA (1) | SA02230286B1 (el) |
| SK (1) | SK9852002A3 (el) |
| YU (1) | YU51902A (el) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10227935B4 (de) * | 2002-06-21 | 2007-10-04 | Heraeus Kulzer Gmbh | Verfahren zur Herstellung einer antibiotische Beschichtung von porösen Körpern sowie Verwendung |
| ITFI20030105A1 (it) * | 2003-04-14 | 2004-10-15 | Italmed Di Galli Giovanna E Pacini Gigliola S N C | Composizione ad uso odontoiatrico per la rigenerazione ossea |
| US20070134287A1 (en) * | 2005-12-09 | 2007-06-14 | Biomet Manufacturing Corp | Method for coating biocompatible substrates with antibiotics |
| DE102006016598A1 (de) * | 2006-04-06 | 2007-11-15 | Heraeus Kulzer Gmbh | Beschichtete Vaskulärimplantate |
| JP5161452B2 (ja) | 2006-10-03 | 2013-03-13 | 日本コヴィディエン株式会社 | 医療用具の製造方法、医療用具の表面に抗生物質を付与する方法および医療用具 |
| CN101721750B (zh) * | 2009-12-25 | 2013-08-07 | 安徽医科大学 | 一种抗菌可降解活性纳米复合仿生骨组织修复材料的制备方法 |
| DE102010055560B4 (de) | 2010-12-23 | 2017-02-23 | Heraeus Medical Gmbh | Beschichtungsvorrichtung |
| DE102012002209A1 (de) * | 2012-02-07 | 2013-08-08 | Carl Freudenberg Kg | Biodegradierbares Vlies für medizinische Zwecke |
| EP3377558B1 (de) | 2016-09-27 | 2020-06-17 | Wacker Chemie AG | Verfahren zur herstellung sphärischer polysilsesquioxanpartikel |
| US10662293B2 (en) | 2016-10-06 | 2020-05-26 | Wacker Chemie Ag | Method for producing spherical polysilsesquioxane particles |
| US11517650B2 (en) | 2017-10-24 | 2022-12-06 | University Of Cincinnati | Antibiotic implant coatings and process for manufacturing implant coatings |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA950831A (en) | 1972-04-25 | 1974-07-09 | Leonard D. Kurtz | Biocidal salts |
| FR2272680B1 (el) * | 1974-05-29 | 1978-07-21 | Hosbon Sa Lab | |
| DE2807132C2 (de) * | 1978-02-20 | 1983-11-03 | Battelle-Institut E.V., 6000 Frankfurt | Implantierbares Pharmaka-Depot |
| DE3206725A1 (de) | 1981-05-13 | 1982-12-02 | Merck Patent Gmbh, 6100 Darmstadt | Schwer loesliche salze von aminoglykosidantibiotika |
| DE3206726A1 (de) | 1982-02-25 | 1983-09-01 | Merck Patent Gmbh, 6100 Darmstadt | Pharmakadepot |
| DE4314871A1 (de) | 1993-05-05 | 1994-11-10 | Merck Patent Gmbh | Lösungsmittel für ein schwerlösliches Gentamicin-Salz |
| DE4404018A1 (de) | 1994-02-09 | 1995-08-10 | Merck Patent Gmbh | Protrahiert freisetzende Darreichungsformen enthaltend Clindamycin-Palmitat |
| US5624704A (en) * | 1995-04-24 | 1997-04-29 | Baylor College Of Medicine | Antimicrobial impregnated catheters and other medical implants and method for impregnating catheters and other medical implants with an antimicrobial agent |
| WO1997038698A1 (en) | 1996-04-18 | 1997-10-23 | University Technology Corporation | Methods for treating middle and inner ear disorders |
| US6417293B1 (en) * | 2000-12-04 | 2002-07-09 | Dow Corning Corporation | Thermoplastic silicone elastomers formed from polyester resins |
| DE10114245A1 (de) | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung |
-
2002
- 2002-05-17 IS IS6390A patent/IS6390A/is unknown
- 2002-06-03 MD MDA20020153A patent/MD2633C2/ro not_active IP Right Cessation
- 2002-06-27 BG BG106881A patent/BG65774B1/bg unknown
- 2002-07-02 CZ CZ20022322A patent/CZ301740B6/cs not_active IP Right Cessation
- 2002-07-04 SK SK985-2002A patent/SK9852002A3/sk unknown
- 2002-07-05 YU YUP51902 patent/YU51902A/sh unknown
- 2002-07-29 CA CA 2396146 patent/CA2396146C/en not_active Expired - Fee Related
- 2002-07-31 IL IL15099902A patent/IL150999A0/xx not_active IP Right Cessation
- 2002-08-12 GE GEAP2002004867 patent/GEP20043333B/en unknown
- 2002-08-13 US US10/217,788 patent/US6984410B2/en not_active Expired - Fee Related
- 2002-08-14 PT PT02018322T patent/PT1287818E/pt unknown
- 2002-08-14 EP EP20020018322 patent/EP1287818B1/de not_active Expired - Lifetime
- 2002-08-14 DK DK02018322T patent/DK1287818T3/da active
- 2002-08-14 DE DE50211246T patent/DE50211246D1/de not_active Expired - Lifetime
- 2002-08-14 ES ES02018322T patent/ES2295268T3/es not_active Expired - Lifetime
- 2002-08-19 AU AU2002300656A patent/AU2002300656B2/en not_active Ceased
- 2002-08-20 HR HR20020680A patent/HRP20020680B1/xx not_active IP Right Cessation
- 2002-08-27 MX MXPA02008326A patent/MXPA02008326A/es active IP Right Grant
- 2002-08-27 NZ NZ521043A patent/NZ521043A/en not_active IP Right Cessation
- 2002-08-28 NO NO20024101A patent/NO20024101L/no not_active Application Discontinuation
- 2002-08-28 JP JP2002249580A patent/JP3740449B2/ja not_active Expired - Fee Related
- 2002-08-28 BR BR0203427A patent/BR0203427A/pt not_active IP Right Cessation
- 2002-08-29 PL PL355778A patent/PL206972B1/pl not_active IP Right Cessation
- 2002-08-30 HU HU0202916A patent/HUP0202916A3/hu unknown
- 2002-08-30 RU RU2002123420A patent/RU2236261C2/ru not_active IP Right Cessation
- 2002-08-30 EE EEP200200491A patent/EE200200491A/xx unknown
- 2002-08-30 CN CNB02141503XA patent/CN1203903C/zh not_active Expired - Fee Related
- 2002-09-03 SA SA02230286A patent/SA02230286B1/ar unknown
-
2008
- 2008-01-18 CY CY081100074T patent/CY1107271T1/el unknown
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