CY1105371T1 - Νευροπροστατευτικα 7-βητα-υδροξυστepοειδη - Google Patents

Νευροπροστατευτικα 7-βητα-υδροξυστepοειδη

Info

Publication number
CY1105371T1
CY1105371T1 CY20051101355T CY051101355T CY1105371T1 CY 1105371 T1 CY1105371 T1 CY 1105371T1 CY 20051101355 T CY20051101355 T CY 20051101355T CY 051101355 T CY051101355 T CY 051101355T CY 1105371 T1 CY1105371 T1 CY 1105371T1
Authority
CY
Cyprus
Prior art keywords
hydroxystepoids
neuroprotective
beta
hydroxysteroids
oxo
Prior art date
Application number
CY20051101355T
Other languages
English (en)
Inventor
Ernst Wulfert
Ashley Ker Pringle
Lars Eric Sundstrom
Original Assignee
Hunter-Fleming Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hunter-Fleming Limited filed Critical Hunter-Fleming Limited
Publication of CY1105371T1 publication Critical patent/CY1105371T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Τα 3-Υδροξυ-7β-υδροξυστεροειδή και τα 3-οξο-7β-υδροξυστεροειδή και οι φαρμακευτικώς αποδεκτοί εστέρες εξ αυτών ήσαν χρήσιμοι για την προστασία έναντι της νευρωνικής βλάβης.
CY20051101355T 2000-06-29 2005-11-07 Νευροπροστατευτικα 7-βητα-υδροξυστepοειδη CY1105371T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0016027A GB2363984A (en) 2000-06-29 2000-06-29 Protection against neuronal damage using 3-hydroxy-7 -hydroxy steroids and 3-oxo-7 -hydroxy steroids
EP01945490A EP1294381B1 (en) 2000-06-29 2001-06-29 Neuroprotective 7-beta-hydroxysteroids

Publications (1)

Publication Number Publication Date
CY1105371T1 true CY1105371T1 (el) 2010-04-28

Family

ID=9894710

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20051101355T CY1105371T1 (el) 2000-06-29 2005-11-07 Νευροπροστατευτικα 7-βητα-υδροξυστepοειδη

Country Status (23)

Country Link
US (2) US20030186953A1 (el)
EP (1) EP1294381B1 (el)
JP (1) JP2004501195A (el)
KR (1) KR100829490B1 (el)
CN (1) CN100441189C (el)
AT (1) ATE303152T1 (el)
AU (2) AU2001267705B2 (el)
CA (1) CA2414583C (el)
CY (1) CY1105371T1 (el)
CZ (1) CZ305306B6 (el)
DE (1) DE60113112T2 (el)
DK (1) DK1294381T3 (el)
ES (1) ES2247141T3 (el)
GB (1) GB2363984A (el)
HK (1) HK1052299B (el)
HU (1) HU229265B1 (el)
IL (2) IL153540A0 (el)
NO (1) NO332089B1 (el)
PL (1) PL200698B1 (el)
RU (1) RU2258511C2 (el)
SI (1) SI1294381T1 (el)
WO (1) WO2002000224A1 (el)
ZA (1) ZA200210214B (el)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2363983A (en) * 2000-06-29 2002-01-16 Hunter Fleming Ltd Protection against neuronal damage using 7-hydroxyepiandrosterone
GB2378898A (en) * 2001-08-14 2003-02-26 Hunter Fleming Ltd Prophylactic and therapeutic use of hydroxysteroids
EP2298316A1 (en) * 2002-08-28 2011-03-23 Harbor BioSciences, Inc. Therapeutic treatment methods
GB0409498D0 (en) * 2004-04-28 2004-06-02 Hunter Fleming Ltd Transdermal steroid formulation
US7910755B2 (en) * 2004-09-29 2011-03-22 Harbor Biosciences, Inc. Stem cell expansion and uses
WO2006058007A2 (en) * 2004-11-23 2006-06-01 Celgene Corporation Jnk inhibitors for treatment of cns injury
WO2008063128A1 (en) 2006-11-21 2008-05-29 Umecrine Ab The use of pregnane and androstane steroids for the manufacture of a pharmaceutical composition for the treatment of cns disorders
GB0623971D0 (en) * 2006-11-30 2007-01-10 Hunter Fleming Ltd Modulation of prostaglandin/cyclooxygenase metabolic pathways
JP2010511028A (ja) * 2006-11-30 2010-04-08 ハンター−フレミング・リミテッド プロスタグランジン／シクロオキシゲナーゼの代謝経路の調節
CZ2008434A3 (cs) * 2008-07-10 2009-12-09 Ústav organické chemie a biochemie Akademie ved CR, v. v. i. Pregnanové anionické slouceniny, zpusob jejich výroby a jejich použití
CU20110244A7 (es) 2011-12-27 2013-08-29 Ct De Investigación Y Desarrollo De Medicamentos Cidem Sistemas espiroesteroidales con efectos neuroactivos y anti-inflamatorios
DE102012001361A1 (de) 2012-01-24 2013-07-25 Linde Aktiengesellschaft Verfahren zum Kaltgasspritzen
US20160362442A1 (en) * 2015-06-10 2016-12-15 IronMag Labs Method For DHEA Enanthate Processing

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292730A (en) * 1990-08-29 1994-03-08 Humanetics Corporation Modulation of immune system with Δ5-androstenes
FR2696934B1 (fr) * 1992-10-20 1995-06-02 Conservatoire Nal Arts Metiers Dérivés de stéroïdes naturels 3B hydroxyles ayant des propriétés de déclenchement et de stimulation de l'immunité, composition les contenant et procédé pour les obtenir.
HUT72968A (en) * 1993-03-09 1996-06-28 Univ Utah Res Found Process for producing pharmaceutical composition which is applicable for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome
DE69634039T2 (de) * 1995-06-06 2005-12-08 Euro-Celtique S.A. Steroidderivate der Androstan- und der Pregnanreihe
GB2317826B (en) * 1995-08-29 1999-12-15 Univ Edinburgh Regulation of intracellular glucocorticoid concentrations
US5985242A (en) * 1995-10-27 1999-11-16 Praecis Pharmaceuticals, Inc. Modulators of β-amyloid peptide aggregation comprising D-amino acids
AU716503B2 (en) * 1996-04-09 2000-02-24 Btg International Limited Neurosteroids
CN1222851A (zh) * 1996-04-09 1999-07-14 英国技术集团国际有限公司 7α－取代的类固醇用于治疗神经精神病、免疫或内分泌疾病的用途
EP1586584A1 (en) * 1996-08-27 2005-10-19 Praecis Pharmaceuticals Incorporated Modulators of beta-amyloid peptide aggregation comprising D-amino acids
WO1999015179A1 (en) * 1997-09-25 1999-04-01 Regents Of The University Of Minnesota Methods of limiting apoptosis of cells
WO1999024400A1 (en) * 1997-11-10 1999-05-20 Vyrex Corporation Probucol esters and uses thereof
JP2004515446A (ja) * 1997-11-24 2004-05-27 ユニバーシティ・オブ・フロリダ・リサーチ・ファンデーション・インコーポレーテッド テストステロン阻害剤及びニューロンの保護のためのその用途
AU3467699A (en) * 1998-04-14 1999-11-01 Pharmadigm, Inc. Method for reducing central nervous system impairment
US6667299B1 (en) * 2000-03-16 2003-12-23 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical compositions and treatment methods
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
WO2001032680A2 (de) * 1999-11-02 2001-05-10 Schering Aktiengesellschaft 18-nor-steroide als selektiv wirksame estrogene
GB0003524D0 (en) * 2000-02-15 2000-04-05 Btg Int Ltd Cytoprotective steroids (II)
GB2363983A (en) * 2000-06-29 2002-01-16 Hunter Fleming Ltd Protection against neuronal damage using 7-hydroxyepiandrosterone

Also Published As

Publication number Publication date
KR20030034112A (ko) 2003-05-01
EP1294381B1 (en) 2005-08-31
SI1294381T1 (sl) 2006-04-30
ZA200210214B (en) 2004-03-17
WO2002000224A1 (en) 2002-01-03
KR100829490B1 (ko) 2008-05-16
DE60113112D1 (de) 2005-10-06
HUP0301317A3 (en) 2006-06-28
IL153540A0 (en) 2003-07-06
GB0016027D0 (en) 2000-08-23
CA2414583C (en) 2010-08-24
DK1294381T3 (da) 2005-10-31
CN1443071A (zh) 2003-09-17
HK1052299B (zh) 2006-01-27
NO20026244D0 (no) 2002-12-27
HUP0301317A2 (hu) 2003-08-28
DE60113112T2 (de) 2006-07-13
PL200698B1 (pl) 2009-01-30
AU2001267705B2 (en) 2005-08-18
ATE303152T1 (de) 2005-09-15
US20100130459A1 (en) 2010-05-27
EP1294381A1 (en) 2003-03-26
US20030186953A1 (en) 2003-10-02
NO332089B1 (no) 2012-06-18
IL153540A (en) 2008-07-08
CN100441189C (zh) 2008-12-10
NO20026244L (no) 2003-02-27
PL359105A1 (en) 2004-08-23
CZ305306B6 (cs) 2015-07-22
CA2414583A1 (en) 2002-01-03
RU2258511C2 (ru) 2005-08-20
AU6770501A (en) 2002-01-08
ES2247141T3 (es) 2006-03-01
JP2004501195A (ja) 2004-01-15
GB2363984A (en) 2002-01-16
HK1052299A1 (en) 2003-09-11
HU229265B1 (en) 2013-10-28

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