CU24425B1 - Amino-heteroaril-benzamidas como inhibidores de cinasa - Google Patents

Amino-heteroaril-benzamidas como inhibidores de cinasa

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Publication number
CU24425B1
CU24425B1 CU2016000052A CU20160052A CU24425B1 CU 24425 B1 CU24425 B1 CU 24425B1 CU 2016000052 A CU2016000052 A CU 2016000052A CU 20160052 A CU20160052 A CU 20160052A CU 24425 B1 CU24425 B1 CU 24425B1
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CU
Cuba
Prior art keywords
benzamidas
heteroaril
amino
inhibitors
cinasa
Prior art date
Application number
CU2016000052A
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English (en)
Other versions
CU20160052A7 (es
Inventor
Jeffrey T Bagdanoff
Yu Ding
Wooseok Han
Zilin Huang
Qun Jiang
Jeff Xianming Jin
Xiang Kou
Patrick Lee
Mika Lindvall
Zhongcheng Min
Yue Pan
Sabina Pecchi
Keith Bruce Pfister
Daniel Poon
Vivek Rauniyar
Xiaojing Michael Wang
Qiong Zhang
Jianguang Zhou
Shejin Zhu
Original Assignee
Novartis Ag
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Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CU20160052A7 publication Critical patent/CU20160052A7/es
Publication of CU24425B1 publication Critical patent/CU24425B1/es

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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract

<p>La presente invención proporciona un compuesto de Ia formula (1), </p> <p>ESPACIO PARA FÓRMULA</p> <p>útil en condiciones asociadas con niveles excesivos o indeseados de actividad de ERK1 y/o ERK2, particularmente cánceres que responden a inhibidores de ERK1 y/o ERK2.</p>
CU2016000052A 2013-11-01 2014-10-29 Amino-heteroaril-benzamidas como inhibidores de cinasa CU24425B1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361898761P 2013-11-01 2013-11-01
CN2014088409 2014-10-11
PCT/US2014/062913 WO2015066188A1 (en) 2013-11-01 2014-10-29 Aminoheteroaryl benzamides as kinase inhibitors

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CU20160052A7 CU20160052A7 (es) 2017-02-02
CU24425B1 true CU24425B1 (es) 2019-06-04

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US (4) US9242996B2 (es)
EP (1) EP3063143B1 (es)
JP (2) JP6219507B2 (es)
KR (1) KR101910720B1 (es)
CN (1) CN105658646B (es)
AP (1) AP2016009099A0 (es)
AU (1) AU2014342338B2 (es)
BR (1) BR112016008133B1 (es)
CA (1) CA2922532C (es)
CL (1) CL2016000807A1 (es)
CU (1) CU24425B1 (es)
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DK (1) DK3063143T3 (es)
DO (1) DOP2016000085A (es)
EA (1) EA032754B1 (es)
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