CU24291B1 - Nuevo procedimiento de síntesis de la agomelatina - Google Patents
Nuevo procedimiento de síntesis de la agomelatinaInfo
- Publication number
- CU24291B1 CU24291B1 CUP2013000087A CU20130087A CU24291B1 CU 24291 B1 CU24291 B1 CU 24291B1 CU P2013000087 A CUP2013000087 A CU P2013000087A CU 20130087 A CU20130087 A CU 20130087A CU 24291 B1 CU24291 B1 CU 24291B1
- Authority
- CU
- Cuba
- Prior art keywords
- synthesis procedure
- new
- agomelatine synthesis
- new agomelatine
- formula
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- YJYPHIXNFHFHND-UHFFFAOYSA-N agomelatine Chemical compound C1=CC=C(CCNC(C)=O)C2=CC(OC)=CC=C21 YJYPHIXNFHFHND-UHFFFAOYSA-N 0.000 title 1
- 229960002629 agomelatine Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/10—Preparation of carboxylic acid amides from compounds not provided for in groups C07C231/02 - C07C231/08
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
- Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1100023A FR2970001B1 (fr) | 2011-01-05 | 2011-01-05 | Nouveau procede de synthese de l'agomelatine |
| PCT/FR2012/000004 WO2012093225A1 (fr) | 2011-01-05 | 2012-01-04 | Nouveau procede de synthese de l'agomelatine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CU20130087A7 CU20130087A7 (es) | 2013-08-29 |
| CU24291B1 true CU24291B1 (es) | 2017-12-08 |
Family
ID=44121614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CUP2013000087A CU24291B1 (es) | 2011-01-05 | 2012-01-04 | Nuevo procedimiento de síntesis de la agomelatina |
Country Status (42)
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2658818B1 (fr) | 1990-02-27 | 1993-12-31 | Adir Cie | Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2866335B1 (fr) | 2004-02-13 | 2006-05-26 | Servier Lab | Nouveau procede de synthese de l'agomelatine |
| FR2934859B1 (fr) * | 2008-08-05 | 2010-08-13 | Servier Lab | Nouveau procede de synthese de l'agomelatine |
-
2011
- 2011-01-05 FR FR1100023A patent/FR2970001B1/fr not_active Expired - Fee Related
- 2011-12-20 JO JOP/2011/0391A patent/JO3085B1/ar active
- 2011-12-30 UY UY0001033847A patent/UY33847A/es unknown
-
2012
- 2012-01-02 SA SA112330135A patent/SA112330135B1/ar unknown
- 2012-01-04 AP AP2013007024A patent/AP3399A/xx active
- 2012-01-04 PE PE2013001436A patent/PE20140169A1/es active IP Right Grant
- 2012-01-04 EA EA201300793A patent/EA024126B1/ru unknown
- 2012-01-04 DK DK12703857.8T patent/DK2661423T3/da active
- 2012-01-04 SI SI201230217T patent/SI2661423T1/sl unknown
- 2012-01-04 CA CA2823584A patent/CA2823584C/fr active Active
- 2012-01-04 GE GEAP201213179A patent/GEP201606576B/en unknown
- 2012-01-04 ME MEP-2015-60A patent/ME02109B/me unknown
- 2012-01-04 PL PL12703857T patent/PL2661423T3/pl unknown
- 2012-01-04 CU CUP2013000087A patent/CU24291B1/xx unknown
- 2012-01-04 AR ARP120100019A patent/AR084779A1/es unknown
- 2012-01-04 WO PCT/FR2012/000004 patent/WO2012093225A1/fr active Application Filing
- 2012-01-04 PT PT127038578T patent/PT2661423E/pt unknown
- 2012-01-04 CN CN201280004722.3A patent/CN103298779B/zh not_active Expired - Fee Related
- 2012-01-04 US US13/977,796 patent/US8871975B2/en active Active
- 2012-01-04 JP JP2013547893A patent/JP5837615B2/ja not_active Expired - Fee Related
- 2012-01-04 MY MYPI2013701042A patent/MY162973A/en unknown
- 2012-01-04 ES ES12703857.8T patent/ES2539173T3/es active Active
- 2012-01-04 KR KR1020137020467A patent/KR101544129B1/ko active IP Right Grant
- 2012-01-04 EP EP12703857.8A patent/EP2661423B1/fr active Active
- 2012-01-04 SG SG2013046354A patent/SG191191A1/en unknown
- 2012-01-04 AU AU2012204817A patent/AU2012204817B2/en not_active Ceased
- 2012-01-04 TW TW101100371A patent/TWI534127B/zh not_active IP Right Cessation
- 2012-01-04 MX MX2013007838A patent/MX2013007838A/es active IP Right Grant
- 2012-01-04 BR BR112013017264A patent/BR112013017264A2/pt not_active IP Right Cessation
- 2012-01-04 RS RS20150268A patent/RS53958B1/en unknown
- 2012-04-01 UA UAA201309591A patent/UA104123C2/uk unknown
-
2013
- 2013-06-19 CR CR20130300A patent/CR20130300A/es unknown
- 2013-06-25 TN TNP2013000273A patent/TN2013000273A1/fr unknown
- 2013-06-25 CL CL2013001881A patent/CL2013001881A1/es unknown
- 2013-07-01 IL IL227282A patent/IL227282A/en active IP Right Grant
- 2013-07-03 GT GT201300176A patent/GT201300176A/es unknown
- 2013-07-03 NI NI201300061A patent/NI201300061A/es unknown
- 2013-07-03 CO CO13156553A patent/CO6731102A2/es unknown
- 2013-07-04 ZA ZA2013/05026A patent/ZA201305026B/en unknown
-
2014
- 2014-03-06 HK HK14102274.7A patent/HK1189217A1/xx not_active IP Right Cessation
-
2015
- 2015-05-12 HR HRP20150504TT patent/HRP20150504T1/hr unknown
- 2015-06-10 CY CY20151100504T patent/CY1116366T1/el unknown
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