CS417291A3 - Cycloalkylthiazole derivatives, process of their preparation andpharmaceuticals prepared therefrom - Google Patents

Cycloalkylthiazole derivatives, process of their preparation andpharmaceuticals prepared therefrom Download PDF

Info

Publication number
CS417291A3
CS417291A3 CS914172A CS417291A CS417291A3 CS 417291 A3 CS417291 A3 CS 417291A3 CS 914172 A CS914172 A CS 914172A CS 417291 A CS417291 A CS 417291A CS 417291 A3 CS417291 A3 CS 417291A3
Authority
CS
Czechoslovakia
Prior art keywords
formula
thiazolyl
hydrogen
ethenyl
compound
Prior art date
Application number
CS914172A
Other languages
Czech (cs)
English (en)
Inventor
George Francis Fikld
John Raymond Wermeulen
William Joseph Zally
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/366,097 external-priority patent/US5001140A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CS417291A3 publication Critical patent/CS417291A3/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CS914172A 1988-07-15 1991-12-30 Cycloalkylthiazole derivatives, process of their preparation andpharmaceuticals prepared therefrom CS417291A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22611288A 1988-07-15 1988-07-15
US33904689A 1989-04-17 1989-04-17
US07/366,097 US5001140A (en) 1989-04-17 1989-06-13 Cycloalkylthiazoles

Publications (1)

Publication Number Publication Date
CS417291A3 true CS417291A3 (en) 1992-09-16

Family

ID=27397563

Family Applications (1)

Application Number Title Priority Date Filing Date
CS914172A CS417291A3 (en) 1988-07-15 1991-12-30 Cycloalkylthiazole derivatives, process of their preparation andpharmaceuticals prepared therefrom

Country Status (21)

Country Link
EP (1) EP0355353B1 (fi)
JP (1) JPH0737454B2 (fi)
KR (1) KR960010352B1 (fi)
AR (1) AR247737A1 (fi)
AU (1) AU626308B2 (fi)
BG (1) BG60765B2 (fi)
CA (1) CA1333906C (fi)
CS (1) CS417291A3 (fi)
DE (1) DE68913856T2 (fi)
DK (1) DK350989A (fi)
ES (1) ES2052825T3 (fi)
FI (1) FI93953C (fi)
HU (2) HU203087B (fi)
IE (1) IE64011B1 (fi)
IL (1) IL90958A0 (fi)
MC (1) MC2049A1 (fi)
MX (1) MX9203632A (fi)
NO (1) NO175476C (fi)
NZ (1) NZ229928A (fi)
PH (1) PH27275A (fi)
PT (1) PT91179B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5273986A (en) * 1992-07-02 1993-12-28 Hoffmann-La Roche Inc. Cycloalkylthiazoles
EP0643045B1 (de) * 1993-09-10 2000-03-08 Novartis AG Chinolin-Verbindungen als Leukotriene Antagonisten
US5508408A (en) * 1993-09-10 1996-04-16 Ciba-Geigy Corporation Quinoline compound
WO1996008479A1 (en) * 1994-09-13 1996-03-21 F. Hoffmann-La Roche Ag A process of making (e)-4-[3-[2-(4-cycloalkyl-2-thiazolyl)ethenyl]phenyl]amino-2,2-alkyldiyl-4-oxobutanoic acid
WO1996027592A1 (en) * 1995-03-03 1996-09-12 F. Hoffmann-La Roche Ag Polymorphic b form of (e)-4-[[3-[2-(4-cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxobutanoic acid
AU5347496A (en) * 1995-04-21 1996-11-07 Daiichi Pharmaceutical Co., Ltd. Ethynylthiazole derivative

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62142168A (ja) * 1985-10-16 1987-06-25 Mitsubishi Chem Ind Ltd チアゾ−ル誘導体及びそれを有効成分とするロイコトリエンきつ抗剤

Also Published As

Publication number Publication date
FI93953B (fi) 1995-03-15
KR900001665A (ko) 1990-02-27
KR960010352B1 (ko) 1996-07-30
JPH0737454B2 (ja) 1995-04-26
HU211268A9 (en) 1995-11-28
HU203087B (en) 1991-05-28
MX9203632A (es) 1992-07-01
MC2049A1 (fr) 1990-07-17
EP0355353A2 (en) 1990-02-28
PH27275A (en) 1993-05-04
DK350989D0 (da) 1989-07-14
FI893434A0 (fi) 1989-07-14
NO892914D0 (no) 1989-07-14
FI93953C (fi) 1995-06-26
BG60765B2 (bg) 1996-02-29
PT91179B (pt) 1995-03-01
DE68913856D1 (de) 1994-04-21
HUT52489A (en) 1990-07-28
AU3828089A (en) 1990-01-18
PT91179A (pt) 1990-02-08
DE68913856T2 (de) 1994-10-20
FI893434A (fi) 1990-01-16
CA1333906C (en) 1995-01-10
IL90958A0 (en) 1990-02-09
AR247737A1 (es) 1995-03-31
NO175476B (no) 1994-07-11
NO175476C (no) 1994-10-19
IE892294L (en) 1990-01-15
ES2052825T3 (es) 1994-07-16
JPH0269468A (ja) 1990-03-08
EP0355353A3 (en) 1990-03-07
NZ229928A (en) 1992-08-26
DK350989A (da) 1990-01-16
IE64011B1 (en) 1995-06-28
AU626308B2 (en) 1992-07-30
EP0355353B1 (en) 1994-03-16
NO892914L (no) 1990-01-16

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