CS271331B2 - Method of mitomycin's n7-amidino-substituted derivatives production - Google Patents

Method of mitomycin's n7-amidino-substituted derivatives production Download PDF

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Publication number
CS271331B2
CS271331B2 CS863117A CS311786A CS271331B2 CS 271331 B2 CS271331 B2 CS 271331B2 CS 863117 A CS863117 A CS 863117A CS 311786 A CS311786 A CS 311786A CS 271331 B2 CS271331 B2 CS 271331B2
Authority
CS
Czechoslovakia
Prior art keywords
mitomycin
chloride
amino
reacted
methoxymitosan
Prior art date
Application number
CS863117A
Other languages
Czech (cs)
English (en)
Other versions
CS311786A2 (en
Inventor
Takushi Kaneko
Henry S L Wong
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of CS311786A2 publication Critical patent/CS311786A2/cs
Publication of CS271331B2 publication Critical patent/CS271331B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/06—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing nitrogen as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CS863117A 1985-04-29 1986-04-29 Method of mitomycin's n7-amidino-substituted derivatives production CS271331B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/728,650 US4652644A (en) 1985-04-29 1985-04-29 Process for preparation of N7 -amidino substituted mitomycin C derivatives

Publications (2)

Publication Number Publication Date
CS311786A2 CS311786A2 (en) 1989-12-13
CS271331B2 true CS271331B2 (en) 1990-09-12

Family

ID=24927725

Family Applications (1)

Application Number Title Priority Date Filing Date
CS863117A CS271331B2 (en) 1985-04-29 1986-04-29 Method of mitomycin's n7-amidino-substituted derivatives production

Country Status (21)

Country Link
US (1) US4652644A (no)
KR (1) KR910002080B1 (no)
CN (1) CN1020731C (no)
AR (1) AR242210A1 (no)
AT (1) AT394724B (no)
CA (1) CA1247617A (no)
CS (1) CS271331B2 (no)
DD (1) DD258011A5 (no)
DK (1) DK168708B1 (no)
ES (1) ES8706685A1 (no)
FI (1) FI83519C (no)
GR (1) GR861152B (no)
HU (1) HU194243B (no)
IT (1) IT1208605B (no)
LU (1) LU86411A1 (no)
NO (1) NO164543C (no)
OA (1) OA08243A (no)
PT (1) PT82471B (no)
SU (1) SU1436881A3 (no)
YU (1) YU45778B (no)
ZW (1) ZW5386A1 (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6354380A (ja) * 1986-08-26 1988-03-08 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
JPH0867676A (ja) * 1994-03-30 1996-03-12 Eisai Kagaku Kk 保護アミノチアゾリル酢酸誘導体
JP3202960B2 (ja) * 1998-02-17 2001-08-27 大塚化学株式会社 ハロゲン化剤及び水酸基のハロゲン化方法
CN104710426B (zh) * 2014-12-12 2017-08-01 常州大学 苯并吡咯里西啶生物碱及其制备方法和用途
CN104478885B (zh) * 2014-12-12 2017-08-01 常州大学 9‑氨基‑9a‑烯丙基苯并吡咯里西啶生物碱的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1135270B (it) * 1980-04-12 1986-08-20 Erba Farmitalia 3-amidino-ansamicine
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
US4567256A (en) * 1983-05-09 1986-01-28 Bristol-Myers Company Amidine process

Also Published As

Publication number Publication date
FI861720A0 (fi) 1986-04-24
IT1208605B (it) 1989-07-10
AT394724B (de) 1992-06-10
ES8706685A1 (es) 1987-07-01
HU194243B (en) 1988-01-28
GR861152B (en) 1986-09-02
KR860008201A (ko) 1986-11-12
US4652644A (en) 1987-03-24
NO861652L (no) 1986-10-30
OA08243A (fr) 1987-10-30
YU70086A (en) 1987-12-31
FI83519C (fi) 1991-07-25
DK193786D0 (da) 1986-04-28
CN1020731C (zh) 1993-05-19
NO164543C (no) 1990-10-17
HUT40665A (en) 1987-01-28
FI83519B (fi) 1991-04-15
CN86101611A (zh) 1986-12-17
ATA101886A (de) 1991-11-15
IT8620228A0 (it) 1986-04-28
AR242210A1 (es) 1993-03-31
PT82471A (en) 1986-05-01
CS311786A2 (en) 1989-12-13
YU45778B (sh) 1992-07-20
ES554469A0 (es) 1987-07-01
NO164543B (no) 1990-07-09
DD258011A5 (de) 1988-07-06
DK193786A (da) 1986-10-30
KR910002080B1 (ko) 1991-04-03
CA1247617A (en) 1988-12-28
ZW5386A1 (en) 1986-10-01
PT82471B (pt) 1988-10-14
DK168708B1 (da) 1994-05-24
FI861720A (fi) 1986-10-30
SU1436881A3 (ru) 1988-11-07
LU86411A1 (fr) 1986-11-05

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