CS245787B2 - Production method of muramylpetides - Google Patents

Production method of muramylpetides Download PDF

Info

Publication number
CS245787B2
CS245787B2 CS835484A CS548483A CS245787B2 CS 245787 B2 CS245787 B2 CS 245787B2 CS 835484 A CS835484 A CS 835484A CS 548483 A CS548483 A CS 548483A CS 245787 B2 CS245787 B2 CS 245787B2
Authority
CS
Czechoslovakia
Prior art keywords
compounds
formula
acid
group
formulas
Prior art date
Application number
CS835484A
Other languages
Czech (cs)
English (en)
Other versions
CS548483A2 (en
Inventor
Albert Hartmann
Oskar Wacker
Gerhard Baschang
Lajos Tarcsay
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to CS848406A priority Critical patent/CS245797B2/cs
Publication of CS548483A2 publication Critical patent/CS548483A2/cs
Publication of CS245787B2 publication Critical patent/CS245787B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other Liquid Machine Or Engine Such As Wave Power Use (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CS835484A 1982-07-23 1983-07-21 Production method of muramylpetides CS245787B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS848406A CS245797B2 (cs) 1982-07-23 1983-07-21 Způsob výroby muramylpeptidů

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH452782 1982-07-23

Publications (2)

Publication Number Publication Date
CS548483A2 CS548483A2 (en) 1985-09-17
CS245787B2 true CS245787B2 (en) 1986-10-16

Family

ID=4277755

Family Applications (1)

Application Number Title Priority Date Filing Date
CS835484A CS245787B2 (en) 1982-07-23 1983-07-21 Production method of muramylpetides

Country Status (23)

Country Link
US (1) US4548923A (xx)
EP (1) EP0099578B1 (xx)
JP (1) JPS5933296A (xx)
KR (1) KR910003641B1 (xx)
AT (1) ATE23536T1 (xx)
AU (1) AU555418B2 (xx)
CA (1) CA1243305A (xx)
CS (1) CS245787B2 (xx)
DD (1) DD210058A5 (xx)
DE (1) DE3367596D1 (xx)
DK (1) DK167193B1 (xx)
ES (2) ES8504676A1 (xx)
FI (1) FI79330C (xx)
GR (1) GR79611B (xx)
HU (1) HU191371B (xx)
IE (1) IE55838B1 (xx)
IL (1) IL69292A (xx)
NO (1) NO167746C (xx)
NZ (1) NZ205002A (xx)
PL (2) PL142641B1 (xx)
PT (1) PT77081B (xx)
SU (1) SU1299516A3 (xx)
ZA (1) ZA835357B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5334583A (en) * 1982-07-23 1994-08-02 Ciba-Geigy Corp. Use of sugar derivatives for the prophylaxis and treatment of virus infections
US5189017A (en) * 1982-07-23 1993-02-23 Ciba-Geigy Corporation Use of sugar derivatives for the prophylaxis and treatment of virus infections
FI852105L (fi) * 1984-05-29 1985-11-30 Ciba Geigy Ag Acylerade sockerderivat, foerfarande foer deras framstaellning och deras anvaendning.
DE3572491D1 (en) * 1984-07-25 1989-09-28 Ciba Geigy Ag Phosphatidyl compounds, process for their preparation and their use
JPS6157597A (ja) * 1984-08-29 1986-03-24 Toshiyuki Hamaoka ムラミルペプチド活性エステル誘導体
US4885285A (en) * 1984-09-13 1989-12-05 Ciba-Geigy Corporation Phosphorus compounds, processes for their manufacture, and their use
US4873322A (en) * 1986-01-24 1989-10-10 Ciba-Geigy Corporation Saccharide derivatives and processes for their manufacture
US4994440A (en) * 1989-02-13 1991-02-19 Creaven Patrick J Method for the treatment of renal cell carcinoma
FR2732604B1 (fr) * 1995-04-07 1997-06-06 Vacsyn Sa Derives et conjugues du mdp presentant une activite stimulatrice de la fonction hematopoietique et compositions les contenant
AU2002950657A0 (en) * 2002-08-08 2002-09-12 Alchemia Limited Derivatives of monosaccharides for drug discovery
AU2002951995A0 (en) * 2002-10-11 2002-10-31 Alchemia Limited Classes of compounds that interact with gpcrs
WO2005039504A2 (en) * 2003-10-24 2005-05-06 Eisai Co., Ltd. Compounds and methods for treating toll-like receptor 2-related diseases and conditions
CN111808131B (zh) * 2019-04-11 2021-09-17 中国科学院大连化学物理研究所 一对有效抑制Aβ(1-40)聚集和纤维化的手性磷脂分子及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2428051A1 (fr) * 1978-06-05 1980-01-04 Anvar Nouveaux composes du type muramyl-peptide et medicaments les contenant
FI75578C (fi) * 1979-07-25 1988-07-11 Ciba Geigy Ag Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider.
FI803077A (fi) * 1979-10-12 1981-04-13 Ciba Geigy Ag Foerfarande foer framstaellning av myramylpeptider
GR78246B (xx) * 1981-01-23 1984-09-26 Ciba Geigy Ag

Also Published As

Publication number Publication date
PL142641B1 (en) 1987-11-30
PT77081A (en) 1983-08-01
NO167746C (no) 1991-12-04
FI832639A (fi) 1984-01-24
ZA835357B (en) 1984-03-28
DD210058A5 (de) 1984-05-30
ES524386A0 (es) 1985-04-16
DK167193B1 (da) 1993-09-13
NZ205002A (en) 1987-11-27
EP0099578B1 (de) 1986-11-12
FI79330B (fi) 1989-08-31
DK337883D0 (da) 1983-07-22
GR79611B (xx) 1984-10-31
NO832691L (no) 1984-01-24
PL142775B1 (en) 1987-11-30
AU555418B2 (en) 1986-09-25
AU1721883A (en) 1984-01-26
ATE23536T1 (de) 1986-11-15
FI79330C (fi) 1989-12-11
PT77081B (en) 1986-04-11
DE3367596D1 (en) 1987-01-02
CS548483A2 (en) 1985-09-17
HU191371B (en) 1987-02-27
SU1299516A3 (ru) 1987-03-23
JPS5933296A (ja) 1984-02-23
FI832639A0 (fi) 1983-07-20
US4548923A (en) 1985-10-22
DK337883A (da) 1984-01-24
EP0099578A1 (de) 1984-02-01
KR840005733A (ko) 1984-11-16
KR910003641B1 (ko) 1991-06-07
IL69292A0 (en) 1983-11-30
IE831727L (en) 1984-01-23
NO167746B (no) 1991-08-26
IL69292A (en) 1987-03-31
IE55838B1 (en) 1991-01-30
ES8504676A1 (es) 1985-04-16
CA1243305A (en) 1988-10-18
ES8607980A1 (es) 1986-06-01
PL243132A1 (en) 1985-03-12
PL250150A1 (en) 1985-06-04
ES539505A0 (es) 1986-06-01

Similar Documents

Publication Publication Date Title
US4446128A (en) Antigen derivatives and processes for their preparation
NO157177B (no) Analogifremgangsmaate til fremstilling av farmakologisk virksomme muramylpeptider.
CS245787B2 (en) Production method of muramylpetides
US5342977A (en) Aminosulfonic acid derivatives and processes for their preparation
CA1318457C (en) Partially retro-inverted tuftsin analogues, method for the preparation thereof and pharmaceutical compositions containing them
CA3152529A1 (en) Asialoglycoprotein receptor mediated delivery of therapeutically active conjugates
FI78300B (fi) Foerfarande foer framstaellning av farmakologiskt verkande fosfatidylfoereningar.
EP0635026B1 (en) Novel lipophilic oligopeptides with immunomodulating activity
SK287682B6 (sk) Pentasacharidový konjugát, spôsob jeho prípravy, farmaceutický prostriedok s jeho obsahom a jeho použitie
AU597571B2 (en) Acylated hexose derivatives and processes for the manufacture thereof
CA1262015A (en) Acylated sugar derivatives, processes for their manufacture, and their use
CS245797B2 (cs) Způsob výroby muramylpeptidů
NO860625L (no) Acylerte heksosederivater og fremgangsmaater til fremstilling derav.
US4574058A (en) Antigen derivatives and processes for their preparation
JPS61194099A (ja) アシル化ヘキソース誘導体及び該誘導体を含む医薬製剤
CN107459556B (zh) 左旋维c-2-氧乙酰-pakpak，其合成，活性和应用
KR830002059B1 (ko) 멀아밀-펲타이드형태인 신규 화합물의 제조방법
JPH06107681A (ja) ペプチド誘導体
JPH05163300A (ja) ペプチド誘導体およびその用途