CS235036B2 - Method of 4"-epierythromycine a production - Google Patents

Method of 4"-epierythromycine a production Download PDF

Info

Publication number
CS235036B2
CS235036B2 CS831371A CS137183A CS235036B2 CS 235036 B2 CS235036 B2 CS 235036B2 CS 831371 A CS831371 A CS 831371A CS 137183 A CS137183 A CS 137183A CS 235036 B2 CS235036 B2 CS 235036B2
Authority
CS
Czechoslovakia
Prior art keywords
reaction
epierythromycin
product
hydrogen
carbonate
Prior art date
Application number
CS831371A
Other languages
Czech (cs)
English (en)
Inventor
Frank Ch Sciavolino
Mark A Cuadliana
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to CS837628A priority Critical patent/CS235048B2/cs
Priority to CS837629A priority patent/CS235049B2/cs
Publication of CS235036B2 publication Critical patent/CS235036B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CS831371A 1982-03-01 1983-02-28 Method of 4"-epierythromycine a production CS235036B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CS837628A CS235048B2 (en) 1982-03-01 1983-10-18 Method of semi-synthetical macrolides production
CS837629A CS235049B2 (en) 1982-03-01 1983-10-18 Method of semi-synthetical macrolides production

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/353,547 US4382085A (en) 1982-03-01 1982-03-01 4"-Epi erythromycin A and derivatives thereof as useful antibacterial agents

Publications (1)

Publication Number Publication Date
CS235036B2 true CS235036B2 (en) 1985-04-16

Family

ID=23389603

Family Applications (3)

Application Number Title Priority Date Filing Date
CS831371A CS235036B2 (en) 1982-03-01 1983-02-28 Method of 4"-epierythromycine a production
CS837629A CS235049B2 (en) 1982-03-01 1983-10-18 Method of semi-synthetical macrolides production
CS837628A CS235048B2 (en) 1982-03-01 1983-10-18 Method of semi-synthetical macrolides production

Family Applications After (2)

Application Number Title Priority Date Filing Date
CS837629A CS235049B2 (en) 1982-03-01 1983-10-18 Method of semi-synthetical macrolides production
CS837628A CS235048B2 (en) 1982-03-01 1983-10-18 Method of semi-synthetical macrolides production

Country Status (26)

Country Link
US (1) US4382085A (el)
EP (1) EP0087905B1 (el)
JP (1) JPS58159499A (el)
KR (1) KR850000965B1 (el)
AT (1) ATE15048T1 (el)
AU (1) AU555208B2 (el)
CA (1) CA1178596A (el)
CS (3) CS235036B2 (el)
DD (1) DD211565A5 (el)
DE (1) DE3360589D1 (el)
DK (1) DK157495C (el)
EG (1) EG16630A (el)
ES (2) ES8403928A1 (el)
FI (1) FI74287C (el)
GR (1) GR78094B (el)
GT (1) GT198301599A (el)
HU (1) HU193157B (el)
IE (1) IE56056B1 (el)
IL (1) IL68004A (el)
NO (1) NO155932C (el)
NZ (1) NZ203417A (el)
PH (1) PH17908A (el)
PL (1) PL138758B1 (el)
PT (1) PT76298B (el)
RO (1) RO86647B (el)
ZA (1) ZA831356B (el)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4526889A (en) * 1982-11-15 1985-07-02 Pfizer Inc. Epimeric azahomoerythromycin A derivative, intermediates and method of use
PH19293A (en) * 1982-11-15 1986-03-04 Pfizer Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof
GR80277B (en) * 1983-09-06 1985-01-04 Pfizer Azahomoerythromycin b derivatives and intermediates therefor
JPS60120895A (ja) * 1983-12-02 1985-06-28 Taisho Pharmaceut Co Ltd ６−０−メチル−２′−０，ν−ビス（ベンジルオキシカルボニル）−ν−デメチルエリスロマイシンａの製法
JPS60214796A (ja) * 1984-04-06 1985-10-28 Taisho Pharmaceut Co Ltd ６−０−メチルエリスロマイシン類の製法
EP0184921A3 (en) * 1984-12-08 1986-10-29 Beecham Group Plc Erythromycin derivatives
US4783811A (en) * 1984-12-27 1988-11-08 Texas Instruments Incorporated Method and apparatus for determining syllable boundaries
US4681872A (en) * 1985-11-12 1987-07-21 Abbott Laboratories Erythromycin A 11,12-carbonate and method of use
US4640910A (en) * 1985-11-12 1987-02-03 Abbott Laboratories Erythromycin A silylated compounds and method of use
US4833236A (en) * 1986-05-02 1989-05-23 Taisho Pharmaceutical Co., Ltd. Erythromycin derivatives
DK0699207T3 (da) * 1993-05-19 1997-12-08 Pfizer Mellemprodukt til azithromycin
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
US5605889A (en) * 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin
CA2492846C (en) * 2002-08-29 2012-09-25 Kosan Biosciences, Inc. Motilide compounds
WO2004101592A1 (ja) * 2003-05-19 2004-11-25 Taisho Pharmaceutical Co., Ltd. エリスロマイシンａ誘導体の製造方法
US7211568B2 (en) * 2003-12-18 2007-05-01 Kosan Biosciences Incorporated 9-Desoxoerythromycin compounds as prokinetic agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3417077A (en) * 1966-05-16 1968-12-17 Lilly Co Eli Erythromycin derivative and process for the preparation thereof
US3884904A (en) * 1973-06-21 1975-05-20 Abbott Lab 11-Substituted erythromycin B derivatives
US3884903A (en) * 1973-06-21 1975-05-20 Abbott Lab 4{41 -Deoxy-4{41 -oxoerythromycin B derivatives
SE445223B (sv) * 1977-02-04 1986-06-09 Pfizer Sett att framstella 4"-amino-erytomylin-a-derivat
US4150220A (en) * 1977-02-04 1979-04-17 Pfizer Inc. Semi-synthetic 4"-erythromycin A derivatives

Also Published As

Publication number Publication date
KR840003647A (ko) 1984-09-15
AU555208B2 (en) 1986-09-18
US4382085A (en) 1983-05-03
RO86647A (ro) 1985-04-17
ES520177A0 (es) 1984-04-01
DK96783D0 (da) 1983-02-28
DD211565A5 (de) 1984-07-18
CS235048B2 (en) 1985-04-16
IE56056B1 (en) 1991-04-10
DK96783A (da) 1983-09-02
GT198301599A (es) 1984-09-13
PL240764A1 (en) 1985-01-02
ATE15048T1 (de) 1985-09-15
RO86647B (ro) 1985-05-01
PL138758B1 (en) 1986-10-31
IL68004A0 (en) 1983-06-15
ZA831356B (en) 1983-11-30
PH17908A (en) 1985-01-25
GR78094B (el) 1984-09-26
DK157495C (da) 1990-06-11
FI74287C (fi) 1988-01-11
CS235049B2 (en) 1985-04-16
PT76298A (en) 1983-03-01
EP0087905B1 (en) 1985-08-21
EG16630A (en) 1991-03-30
ES526323A0 (es) 1985-11-16
IE830411L (en) 1983-09-01
CA1178596A (en) 1984-11-27
ES8602837A1 (es) 1985-11-16
ES8403928A1 (es) 1984-04-01
EP0087905A1 (en) 1983-09-07
NO830686L (no) 1983-09-02
AU1189883A (en) 1983-09-08
IL68004A (en) 1986-11-30
FI830654A0 (fi) 1983-02-28
FI74287B (fi) 1987-09-30
PT76298B (en) 1986-01-27
JPS58159499A (ja) 1983-09-21
NZ203417A (en) 1985-10-11
FI830654L (fi) 1983-09-02
NO155932C (no) 1987-06-24
DE3360589D1 (en) 1985-09-26
DK157495B (da) 1990-01-15
KR850000965B1 (ko) 1985-07-02
HU193157B (en) 1987-08-28
NO155932B (no) 1987-03-16
JPH0140039B2 (el) 1989-08-24

Similar Documents

Publication Publication Date Title
DK172636B1 (en) 6-o-methylerythromycin a derivative
CS235036B2 (en) Method of 4"-epierythromycine a production
PL143281B1 (en) Process for preparing 4"-api-9-desketo-9a-methyl-9a-aza-9a-homoerythromycin a
US4382086A (en) 9-Dihydro-11,12-ketal derivatives of erythromycin A and epi-erythromycin A
JPS5827800B2 (ja) 新規抗菌剤
JPH04504259A (ja) エリスロマイシン誘導体
CA1323026C (en) Antibacterial 9-deoxo-9a-allyl and propargyl-9a-aza- 9a-homoerythromycin a derivatives
US4585759A (en) Antibacterial derivatives of a neutral macrolide
CS200536B2 (en) Method of producing epimeric 4-amino oleandomycin derivatives
EP0114486B1 (en) Alkylation of oleandomycin
GB1585315A (en) Erythromycin a derivatives
US4363803A (en) 3",4"-Oxyallylene erythromycin and oleandomycin, composition and method of use
US4413119A (en) Semi-synthetic macrolides
US4169890A (en) Pharmaceutical composition containing 5"-amino-3',5"-dideoxy-ribostamycin and intermediate compounds
US4064143A (en) Oleandomycin derivatives
KR850000963B1 (ko) N-메틸 11-아자-10-데옥소-10-디하이드로 에리스로마이신 a 및 그 중간체의 제조방법
CA1250284A (en) Antibacterial epimeric azahomoerythromycin a derivative and production thereof
HU211493A9 (en) Derivatives 10, 11, 12, 13-tetrahydrodesmycosin, processes for preparation and use thereof in pharmaceuticals
DK158473B (da) Cycliske ethere af 9-deoxo-9a-aza-9a-homoerythromycin a og dettes 4ae-epimer, forbindelser til anvendelse som udgangsmateriale ved deres fremstilling, farmaceutiske praeparater indeholdende de cycliske ethere og anvendelse af de cycliske ethere til fremstilling af laegemidler