CS227001B2 - Method of preparing thiazoloisoquinoline derivatives - Google Patents

Method of preparing thiazoloisoquinoline derivatives Download PDF

Info

Publication number
CS227001B2
CS227001B2 CS743796A CS379674A CS227001B2 CS 227001 B2 CS227001 B2 CS 227001B2 CS 743796 A CS743796 A CS 743796A CS 379674 A CS379674 A CS 379674A CS 227001 B2 CS227001 B2 CS 227001B2
Authority
CS
Czechoslovakia
Prior art keywords
group
derivative
thiazoloisoquinoline
carbonic acid
converted
Prior art date
Application number
CS743796A
Other languages
Czech (cs)
English (en)
Inventor
Kalman Harsanyi
Kalman Takacs
Pal Kiss
Laszlo Szekeres
Gyula Papp
Va Gyoer Benedek
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of CS227001B2 publication Critical patent/CS227001B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS743796A 1973-05-30 1974-05-28 Method of preparing thiazoloisoquinoline derivatives CS227001B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI1381A HU170680B (no) 1973-05-30 1973-05-30

Publications (1)

Publication Number Publication Date
CS227001B2 true CS227001B2 (en) 1984-04-16

Family

ID=10994482

Family Applications (2)

Application Number Title Priority Date Filing Date
CS743796A CS227001B2 (en) 1973-05-30 1974-05-28 Method of preparing thiazoloisoquinoline derivatives
CS746737A CS226901B1 (en) 1973-05-30 1974-05-28 Thiazoloisoquinoline derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
CS746737A CS226901B1 (en) 1973-05-30 1974-05-28 Thiazoloisoquinoline derivatives

Country Status (24)

Country Link
US (1) US3979397A (no)
JP (3) JPS6014038B2 (no)
AR (1) AR213611A1 (no)
AT (1) AT349018B (no)
BE (1) BE815679A (no)
BG (1) BG22391A3 (no)
CA (1) CA1037042A (no)
CH (2) CH622807A5 (no)
CS (2) CS227001B2 (no)
DD (1) DD119595A5 (no)
DE (1) DE2426267C2 (no)
DK (1) DK151028C (no)
EG (1) EG11439A (no)
ES (1) ES426773A1 (no)
FI (1) FI57262C (no)
FR (1) FR2241309B1 (no)
HU (1) HU170680B (no)
IL (1) IL44895A (no)
NL (1) NL176944C (no)
NO (1) NO150281C (no)
PL (1) PL101194B1 (no)
SE (1) SE419647B (no)
SU (1) SU569291A3 (no)
YU (1) YU37172B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4163786A (en) * 1973-05-30 1979-08-07 Chinoin Pharmaceutical And Chemical Works Ltd. Thiazoloisoquinolines with coronary and respiratory effects
US4062850A (en) * 1973-05-30 1977-12-13 Chinoin Pharmaceutical And Chemical Works Ltd. Thiazoloisoquinolines with coronary and respiratory effects
OA05403A (fr) * 1975-08-06 1981-02-28 Rhone Poulenc Ind Nouveaux dérivés de la thiazolo [3,4-b] isoquinoléine et leur procédé de préparation.
US4108999A (en) * 1977-02-22 1978-08-22 Rhone-Poulenc Industries Thiazolo[3,4-b]isoquinoline derivatives, pharmaceutical compositions containing them and pharmaceutical methods using them
NL7908655A (nl) * 1978-12-07 1980-06-10 Rhone Poulenc Ind Nieuwe thienopyridine-derivaten, de bereiding ervan, alsmede farmaceutische preparaten, die de nieuwe derivaten bevatten.
HU178454B (en) * 1979-07-02 1982-05-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing new isoquinoline derivatives containing sulphur
JPH0332569Y2 (no) * 1986-05-27 1991-07-10

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3042671A (en) * 1959-10-07 1962-07-03 Pfizer & Co C Benzopyridocolines
US3455933A (en) * 1966-11-15 1969-07-15 American Home Prod Thiazolo and thiazino isoquinoline derivatives
US3665007A (en) * 1970-05-04 1972-05-23 Squibb & Sons Inc Thiazolo (3,4-a) benzimidazoles and derivatives thereof

Also Published As

Publication number Publication date
FI57262C (fi) 1980-07-10
SU569291A3 (ru) 1977-08-15
FR2241309B1 (no) 1977-11-04
NL176944B (nl) 1985-02-01
HU170680B (no) 1977-08-28
YU148074A (en) 1982-06-18
IL44895A (en) 1979-07-25
CS226901B1 (en) 1984-04-16
BG22391A3 (bg) 1977-02-20
DK151028B (da) 1987-10-12
CA1037042A (en) 1978-08-22
DD119595A5 (no) 1976-05-05
ATA433674A (de) 1978-08-15
CH620220A5 (no) 1980-11-14
CH622807A5 (no) 1981-04-30
SE7407049L (no) 1974-12-02
EG11439A (en) 1978-12-31
DK289774A (no) 1975-01-20
ES426773A1 (es) 1976-07-16
SE419647B (sv) 1981-08-17
DK151028C (da) 1988-03-14
DE2426267A1 (de) 1975-01-09
BE815679A (fr) 1974-09-16
JPS57145884A (en) 1982-09-09
AR213611A1 (es) 1979-02-28
DE2426267C2 (de) 1984-02-09
NO150281C (no) 1984-09-19
JPS591714B2 (ja) 1984-01-13
FI164474A (no) 1974-12-01
FR2241309A1 (no) 1975-03-21
AT349018B (de) 1979-03-12
JPS6014038B2 (ja) 1985-04-11
FI57262B (fi) 1980-03-31
NO741939A (no) 1974-12-03
US3979397A (en) 1976-09-07
NO150281B (no) 1984-06-12
NL7407280A (no) 1974-12-03
JPS5842195B2 (ja) 1983-09-17
PL101194B1 (pl) 1978-12-30
JPS5047999A (no) 1975-04-28
YU37172B (en) 1984-08-31
IL44895A0 (en) 1974-07-31
NL176944C (nl) 1985-07-01
JPS57145885A (en) 1982-09-09

Similar Documents

Publication Publication Date Title
PT88899B (pt) Provesso para a preparacao de tetrahidro-furo {2,3-c}piridinas e de tetrahidro--tieno {2,3-c}piridinas e de composicoes farmaceuticas que as contem
US2924603A (en) Aralkylbenzmorphan derivatives
AU655634B2 (en) New active compounds
FI59253B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-hydroxi-2h-tieno(2,3-e) och (3,4-e)-1,2-tiazin-3-karboxamid-1,1-dioxid-derivat
IL26969A (en) Bis-(3-indole-alkylene or oxoalkylene)-azacyclic or diazacyclic compounds and their preparation
DK141069B (da) Analogifremgangsmåde til fremstilling af 1,5,10,10a-tetrahydrothiazolo (3,4-b)isoquinolinderivater eller syreadditionssalte deraf.
CS227001B2 (en) Method of preparing thiazoloisoquinoline derivatives
JPS6126546B2 (no)
JPH02129168A (ja) 新規化合物、その製法及びそれを含む医薬組成物
IE61070B1 (en) Antiarrhythmic agents
US4013672A (en) 2,5,7,8-Tetrahydro-1,2,4,5,6-pentaazabenzo[6,7]-cyclohepta[1,2,3-cd]-as-indacenes
PL121492B1 (en) Process for preparing novel salts of bis-tetrahydroisoquinolinium-alkyl m-or p-phenylene-dialkanocarboxylatessilanov bis-tetragidroizokhinolino-alkilovykh solejj
JPS5914037B2 (ja) イソキノリン誘導体、その製造方法およびそれを含有する医薬組成物
US3086972A (en) Aza-thiaxanthene derivatives
US3953461A (en) Amino derivatives of thiazolo[5,4-b]pyridine-6-carboxylic acids and esters
US3546220A (en) 2,3-dihydro-1h-pyrido-(2,3-b)(1,4)thiazines
US4163786A (en) Thiazoloisoquinolines with coronary and respiratory effects
US3728383A (en) {60 (m-alkoxyphenoxy) and {60 (m-trifluoro-methylphenoxy) m-toluic acids
US3657271A (en) 1 3-dimethyl-5-methylamino-8-phenylpyrazolo(4 3-e)(1 4)diazepine
US3388133A (en) Benz [b] indolo [2, 3-d] thiopyrylium compounds and processes for their production
US3773746A (en) 1,1'-azo bis(1h-imidazo(1,2-a)pyridinium dibromide compounds
US4994448A (en) Condensed quinolinium and isoquinolinium derivatives
US3845074A (en) Dibenzo(b,f)thiazepin(1,4)-11-yl amino alkanoic acids
NO830611L (no) Imidazotiadiazolalkenkarboksylsyreamider, nye mellomprodukter til deres fremstilling, deres fremstilling og deres anvendles i legemidler
PL121468B1 (en) Process for preparing novel salts of bis-tetrahydroiso-quinolinium-alkyl m-or p-phenylene-di/methan or ethen/-carboxylatesan/karboksilanov bis-tetragidroizokhinolinio-alkilovykh solejj