CS221274B2 - Method of making the new 4-substituted derivatives of daunorubicine - Google Patents

Method of making the new 4-substituted derivatives of daunorubicine Download PDF

Info

Publication number
CS221274B2
CS221274B2 CS777517A CS751777A CS221274B2 CS 221274 B2 CS221274 B2 CS 221274B2 CS 777517 A CS777517 A CS 777517A CS 751777 A CS751777 A CS 751777A CS 221274 B2 CS221274 B2 CS 221274B2
Authority
CS
Czechoslovakia
Prior art keywords
demethoxy
title compound
room temperature
formula
compounds
Prior art date
Application number
CS777517A
Other languages
Czech (cs)
English (en)
Inventor
Luigi Bernardi
Paolo Masi
Antonino Suarato
Federico Arcamone
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of CS221274B2 publication Critical patent/CS221274B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS777517A 1976-11-16 1977-11-15 Method of making the new 4-substituted derivatives of daunorubicine CS221274B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB47601/76A GB1567456A (en) 1976-11-16 1976-11-16 Daunomycin derivatives

Publications (1)

Publication Number Publication Date
CS221274B2 true CS221274B2 (en) 1983-04-29

Family

ID=10445564

Family Applications (1)

Application Number Title Priority Date Filing Date
CS777517A CS221274B2 (en) 1976-11-16 1977-11-15 Method of making the new 4-substituted derivatives of daunorubicine

Country Status (25)

Country Link
US (2) US4166848A (fr)
JP (1) JPS5363366A (fr)
AT (1) AT356268B (fr)
AU (1) AU519681B2 (fr)
BE (1) BE860782A (fr)
CA (1) CA1090787A (fr)
CH (1) CH634336A5 (fr)
CS (1) CS221274B2 (fr)
DE (1) DE2750812C2 (fr)
DK (1) DK148059C (fr)
FI (1) FI63590C (fr)
FR (1) FR2370754B1 (fr)
GB (1) GB1567456A (fr)
GR (1) GR71885B (fr)
HU (1) HU177041B (fr)
IE (1) IE46165B1 (fr)
IL (1) IL53378A (fr)
NL (1) NL7712390A (fr)
NO (1) NO145762C (fr)
NZ (1) NZ185677A (fr)
PH (1) PH14874A (fr)
SE (1) SE435387B (fr)
SU (1) SU897111A3 (fr)
YU (1) YU269977A (fr)
ZA (1) ZA776812B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316985A (en) * 1979-01-16 1982-02-23 Hoffmann-La Roche Inc. Cyclic compounds
US4299822A (en) * 1980-06-09 1981-11-10 Sidney Farber Cancer Institute, Inc. N-Trifluoroacetyladriamycin-14-O-hemiglutarate and -hemiadipate and therapeutic compositions containing same
US4413120A (en) * 1981-04-06 1983-11-01 Purdue Research Foundation Process for producing acosamine, daunosamine, 1-thioacosamine and related compounds
GB8317037D0 (en) * 1983-06-23 1983-07-27 Erba Farmitalia 6-deoxyanthracyclines
US4870058A (en) * 1982-12-20 1989-09-26 Ohio State University Research Foundation 14-Acyloxy-2'-halo-anthracycline anti-cancer antibiotics
WO1985001726A1 (fr) * 1983-10-19 1985-04-25 The University Of Melbourne Precurseurs et analogues de carminomycinone et leurs derives
US4537882A (en) * 1984-05-10 1985-08-27 Ohio State University 4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same
GB8426672D0 (en) * 1984-10-22 1984-11-28 Erba Farmitalia Pharmaceutical compositions
JPS63106741A (ja) * 1986-10-24 1988-05-11 Asahi Optical Co Ltd 色分解光学読取装置
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
WO1989006654A1 (fr) * 1988-01-19 1989-07-27 Board Of Regents, The University Of Texas System Glycosides, compositions liposomiques a base de ces composes et procedes d'utilisation
GB9216962D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives
AU6364094A (en) * 1993-03-12 1994-09-26 Board Of Regents, The University Of Texas System Anthracyclines with unusually high activity against cells resistant to doxorubicin and its analogs
GB9416007D0 (en) * 1994-08-08 1994-09-28 Erba Carlo Spa Anthracyclinone derivatives
GB9418260D0 (en) * 1994-09-09 1994-10-26 Erba Carlo Spa Anthracycline derivatives
DE102004010219B4 (de) * 2004-02-27 2007-02-01 Hans-Knöll-Institut für Naturstoff-Forschung e.V. HKI10311129, neues Antibiotikum, Verfahren zu dessen Herstellung und Arzneimittel enthaltend HKI10311129

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3074975A (en) * 1960-11-07 1963-01-22 American Cyanamid Co Naphthacenequinones
US3201424A (en) * 1962-10-29 1965-08-17 American Cyanamid Co Derivatives of 1, 3, 11, 12-tetrahydroxynaphthacene and 1, 3, 6, 11-tetrahydroxynaphtacene-5, 12-quinone
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
GB1511559A (en) * 1975-09-26 1978-05-24 Farmaceutici Italia Anthracycline glycosides
GB1509875A (en) * 1976-06-14 1978-05-04 Farmaceutici Italia Optically active anthracyclinones and anthracycline glycosides

Also Published As

Publication number Publication date
NL7712390A (nl) 1978-05-18
JPS6133037B2 (fr) 1986-07-31
AT356268B (de) 1980-04-25
GR71885B (fr) 1983-08-04
BE860782A (fr) 1978-03-01
DK502977A (da) 1978-05-17
CA1090787A (fr) 1980-12-02
GB1567456A (en) 1980-05-14
AU3057977A (en) 1979-05-17
US4166848A (en) 1979-09-04
FI63590B (fi) 1983-03-31
FI773433A (fi) 1978-05-17
FR2370754B1 (fr) 1982-10-22
CH634336A5 (de) 1983-01-31
PH14874A (en) 1982-01-08
DE2750812A1 (de) 1978-05-18
IL53378A0 (en) 1978-01-31
NZ185677A (en) 1979-06-19
FR2370754A1 (fr) 1978-06-09
SE435387B (sv) 1984-09-24
ZA776812B (en) 1978-09-27
IE46165B1 (en) 1983-03-09
JPS5363366A (en) 1978-06-06
NO145762B (no) 1982-02-15
IE46165L (en) 1978-05-16
DK148059B (da) 1985-02-18
AU519681B2 (en) 1981-12-17
DE2750812C2 (de) 1986-01-09
NO773892L (no) 1978-05-18
IL53378A (en) 1981-12-31
HU177041B (hu) 1981-06-28
SU897111A3 (ru) 1982-01-07
FI63590C (fi) 1983-07-11
DK148059C (da) 1985-07-29
YU269977A (en) 1982-08-31
SE7712861L (sv) 1978-05-17
US4327029A (en) 1982-04-27
ATA806877A (de) 1979-09-15
NO145762C (no) 1982-05-26

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