IL53378A - 4-demethoxy-4(lower alkoxy,cycloalkyloxy or benzyloxy)-daunomycins and process for the preparation thereof - Google Patents

4-demethoxy-4(lower alkoxy,cycloalkyloxy or benzyloxy)-daunomycins and process for the preparation thereof

Info

Publication number
IL53378A
IL53378A IL53378A IL5337877A IL53378A IL 53378 A IL53378 A IL 53378A IL 53378 A IL53378 A IL 53378A IL 5337877 A IL5337877 A IL 5337877A IL 53378 A IL53378 A IL 53378A
Authority
IL
Israel
Prior art keywords
daunomycins
demethoxy
cycloalkyloxy
benzyloxy
preparation
Prior art date
Application number
IL53378A
Other languages
English (en)
Other versions
IL53378A0 (en
Original Assignee
Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia
Publication of IL53378A0 publication Critical patent/IL53378A0/xx
Publication of IL53378A publication Critical patent/IL53378A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL53378A 1976-11-16 1977-11-14 4-demethoxy-4(lower alkoxy,cycloalkyloxy or benzyloxy)-daunomycins and process for the preparation thereof IL53378A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB47601/76A GB1567456A (en) 1976-11-16 1976-11-16 Daunomycin derivatives

Publications (2)

Publication Number Publication Date
IL53378A0 IL53378A0 (en) 1978-01-31
IL53378A true IL53378A (en) 1981-12-31

Family

ID=10445564

Family Applications (1)

Application Number Title Priority Date Filing Date
IL53378A IL53378A (en) 1976-11-16 1977-11-14 4-demethoxy-4(lower alkoxy,cycloalkyloxy or benzyloxy)-daunomycins and process for the preparation thereof

Country Status (25)

Country Link
US (2) US4166848A (xx)
JP (1) JPS5363366A (xx)
AT (1) AT356268B (xx)
AU (1) AU519681B2 (xx)
BE (1) BE860782A (xx)
CA (1) CA1090787A (xx)
CH (1) CH634336A5 (xx)
CS (1) CS221274B2 (xx)
DE (1) DE2750812C2 (xx)
DK (1) DK148059C (xx)
FI (1) FI63590C (xx)
FR (1) FR2370754B1 (xx)
GB (1) GB1567456A (xx)
GR (1) GR71885B (xx)
HU (1) HU177041B (xx)
IE (1) IE46165B1 (xx)
IL (1) IL53378A (xx)
NL (1) NL7712390A (xx)
NO (1) NO145762C (xx)
NZ (1) NZ185677A (xx)
PH (1) PH14874A (xx)
SE (1) SE435387B (xx)
SU (1) SU897111A3 (xx)
YU (1) YU269977A (xx)
ZA (1) ZA776812B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316985A (en) * 1979-01-16 1982-02-23 Hoffmann-La Roche Inc. Cyclic compounds
US4299822A (en) * 1980-06-09 1981-11-10 Sidney Farber Cancer Institute, Inc. N-Trifluoroacetyladriamycin-14-O-hemiglutarate and -hemiadipate and therapeutic compositions containing same
US4413120A (en) * 1981-04-06 1983-11-01 Purdue Research Foundation Process for producing acosamine, daunosamine, 1-thioacosamine and related compounds
GB8317037D0 (en) * 1983-06-23 1983-07-27 Erba Farmitalia 6-deoxyanthracyclines
US4870058A (en) * 1982-12-20 1989-09-26 Ohio State University Research Foundation 14-Acyloxy-2'-halo-anthracycline anti-cancer antibiotics
JPS61501388A (ja) * 1983-10-19 1986-07-10 ザ　ユニヴア−シテイ　オブ　メルボルン 有機化合物類
US4537882A (en) * 1984-05-10 1985-08-27 Ohio State University 4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same
GB8426672D0 (en) * 1984-10-22 1984-11-28 Erba Farmitalia Pharmaceutical compositions
JPS63106741A (ja) * 1986-10-24 1988-05-11 Asahi Optical Co Ltd 色分解光学読取装置
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
JPH03502327A (ja) * 1988-01-19 1991-05-30 ボード・オブ・リージェンツ，ザ・ユニバーシティ・オブ・テキサス・システム ３’‐デアミノドキソルビシンのエステル体、そのリポソーム組成物およびその使用方法
GB9216962D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives
WO1994020114A1 (en) * 1993-03-12 1994-09-15 Board Of Regents, The University Of Texas System Anthracyclines with unusually high activity against cells resistant to doxorubicin and its analogs
GB9416007D0 (en) * 1994-08-08 1994-09-28 Erba Carlo Spa Anthracyclinone derivatives
GB9418260D0 (en) * 1994-09-09 1994-10-26 Erba Carlo Spa Anthracycline derivatives
DE102004010219B4 (de) * 2004-02-27 2007-02-01 Hans-Knöll-Institut für Naturstoff-Forschung e.V. HKI10311129, neues Antibiotikum, Verfahren zu dessen Herstellung und Arzneimittel enthaltend HKI10311129

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3074975A (en) * 1960-11-07 1963-01-22 American Cyanamid Co Naphthacenequinones
US3201424A (en) * 1962-10-29 1965-08-17 American Cyanamid Co Derivatives of 1, 3, 11, 12-tetrahydroxynaphthacene and 1, 3, 6, 11-tetrahydroxynaphtacene-5, 12-quinone
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
GB1511559A (en) * 1975-09-26 1978-05-24 Farmaceutici Italia Anthracycline glycosides
GB1509875A (en) * 1976-06-14 1978-05-04 Farmaceutici Italia Optically active anthracyclinones and anthracycline glycosides

Also Published As

Publication number Publication date
US4327029A (en) 1982-04-27
SE7712861L (sv) 1978-05-17
AU519681B2 (en) 1981-12-17
PH14874A (en) 1982-01-08
NL7712390A (nl) 1978-05-18
SU897111A3 (ru) 1982-01-07
IL53378A0 (en) 1978-01-31
NZ185677A (en) 1979-06-19
GR71885B (xx) 1983-08-04
GB1567456A (en) 1980-05-14
DK148059B (da) 1985-02-18
US4166848A (en) 1979-09-04
FR2370754B1 (xx) 1982-10-22
IE46165L (en) 1978-05-16
NO145762B (no) 1982-02-15
ZA776812B (en) 1978-09-27
DE2750812A1 (de) 1978-05-18
SE435387B (sv) 1984-09-24
FI63590C (fi) 1983-07-11
JPS6133037B2 (xx) 1986-07-31
NO773892L (no) 1978-05-18
ATA806877A (de) 1979-09-15
CH634336A5 (de) 1983-01-31
JPS5363366A (en) 1978-06-06
YU269977A (en) 1982-08-31
FR2370754A1 (xx) 1978-06-09
CS221274B2 (en) 1983-04-29
CA1090787A (en) 1980-12-02
DK502977A (da) 1978-05-17
FI63590B (fi) 1983-03-31
HU177041B (hu) 1981-06-28
IE46165B1 (en) 1983-03-09
DK148059C (da) 1985-07-29
AU3057977A (en) 1979-05-17
BE860782A (fr) 1978-03-01
NO145762C (no) 1982-05-26
DE2750812C2 (de) 1986-01-09
AT356268B (de) 1980-04-25
FI773433A (fi) 1978-05-17

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