CS215052B2 - Method of making the 1,1-biphenyl-2-ylalkylaminoderivatives - Google Patents

Method of making the 1,1-biphenyl-2-ylalkylaminoderivatives Download PDF

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Publication number
CS215052B2
CS215052B2 CS801665A CS166580A CS215052B2 CS 215052 B2 CS215052 B2 CS 215052B2 CS 801665 A CS801665 A CS 801665A CS 166580 A CS166580 A CS 166580A CS 215052 B2 CS215052 B2 CS 215052B2
Authority
CS
Czechoslovakia
Prior art keywords
alkyl
group
hydrogen
biphenyl
formula
Prior art date
Application number
CS801665A
Other languages
Czech (cs)
English (en)
Inventor
William B Lacefield
Richard L Simon
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Priority to CS81821A priority Critical patent/CS215053B2/cs
Publication of CS215052B2 publication Critical patent/CS215052B2/cs

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CS801665A 1979-03-12 1980-03-11 Method of making the 1,1-biphenyl-2-ylalkylaminoderivatives CS215052B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS81821A CS215053B2 (cs) 1979-03-12 1981-02-04 Způsob výroby 1,1'-bifenyl-2-ylalkylaminoderivátů

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1953479A 1979-03-12 1979-03-12

Publications (1)

Publication Number Publication Date
CS215052B2 true CS215052B2 (en) 1982-07-30

Family

ID=21793713

Family Applications (1)

Application Number Title Priority Date Filing Date
CS801665A CS215052B2 (en) 1979-03-12 1980-03-11 Method of making the 1,1-biphenyl-2-ylalkylaminoderivatives

Country Status (31)

Country Link
EP (1) EP0015776B1 (xx)
JP (1) JPS55127347A (xx)
KR (1) KR840000103B1 (xx)
AR (1) AR228852A1 (xx)
AT (1) AT367395B (xx)
AU (1) AU528060B2 (xx)
BE (1) BE882167A (xx)
CA (1) CA1144926A (xx)
CH (1) CH644094A5 (xx)
CS (1) CS215052B2 (xx)
DD (1) DD149664A5 (xx)
DE (1) DE3060611D1 (xx)
DK (1) DK103480A (xx)
ES (6) ES489469A0 (xx)
FI (1) FI800736A (xx)
FR (1) FR2451363A1 (xx)
GB (1) GB2046256B (xx)
GR (1) GR68036B (xx)
HU (1) HU180334B (xx)
IE (1) IE49552B1 (xx)
IL (1) IL59557A (xx)
IT (1) IT1140773B (xx)
LU (1) LU82237A1 (xx)
MX (1) MX6219E (xx)
NZ (1) NZ193079A (xx)
PH (1) PH14749A (xx)
PL (1) PL121662B1 (xx)
PT (1) PT70928A (xx)
RO (1) RO79906A (xx)
SU (2) SU940645A3 (xx)
ZA (1) ZA801421B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100470454B1 (ko) * 2002-05-14 2005-02-05 대한민국 돼지 사료공급을 위한 자동조절급이기
CN101035756A (zh) * 2004-06-17 2007-09-12 南卡罗来纳州医科大学研究发展基金会 非天然氨基酸
EP2511273B8 (en) * 2011-04-15 2019-06-26 Hivih Inhibitors of viral replication, their process of preparation and their therapeutical uses
EP2821104A1 (en) 2013-07-05 2015-01-07 Laboratoire Biodim Inhibitors of viral replication, their process of preparation and their therapeutical uses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES236010A1 (es) * 1956-06-29 1957-12-16 Lab Pharmaceutica Dr C Janssen UN PROCEDIMIENTO PARA PREPARAR NUEVOS DERIVADOS PARASIMPATICOLiTICAMENTE ACTIVOS DE ALFAS-DEFENIL PROPANO
US3433836A (en) * 1966-01-14 1969-03-18 Rexall Drug Chemical Alpha-diaryl alpha,omega-alkylene glycol-dilower-alkylamines
GB1475314A (en) * 1973-11-02 1977-06-01 Cm Ind Phenyl-propylamine derivatives
IL48319A0 (en) * 1974-10-26 1975-12-31 Merck Patent Gmbh Araliphatic nitrogen compounds and a process for their preparation
GB1523655A (en) * 1975-02-10 1978-09-06 Armour Pharma 4-(4-biphenylyl) butylamines and treatment of the animal organism therewith

Also Published As

Publication number Publication date
AR228852A1 (es) 1983-04-29
ES8201526A1 (es) 1981-12-16
PL222601A1 (xx) 1981-01-30
ES8105262A1 (es) 1981-05-16
EP0015776A1 (en) 1980-09-17
ES497209A0 (es) 1981-12-16
FR2451363A1 (fr) 1980-10-10
IT1140773B (it) 1986-10-10
ES8201529A1 (es) 1981-12-16
DD149664A5 (de) 1981-07-22
AT367395B (de) 1982-06-25
ZA801421B (en) 1981-10-28
GB2046256A (en) 1980-11-12
MX6219E (es) 1984-12-21
EP0015776B1 (en) 1982-06-30
NZ193079A (en) 1982-05-31
PL121662B1 (en) 1982-05-31
PT70928A (en) 1980-04-01
ES8201528A1 (es) 1981-12-16
ES497208A0 (es) 1981-12-16
KR830001854A (ko) 1983-05-19
GB2046256B (en) 1983-04-20
ES8201527A1 (es) 1981-12-16
BE882167A (fr) 1980-09-11
ES497207A0 (es) 1981-12-16
DK103480A (da) 1980-09-13
ES497206A0 (es) 1981-12-16
IE800493L (en) 1980-09-12
HU180334B (en) 1983-02-28
SU1022655A3 (ru) 1983-06-07
RO79906A (ro) 1982-10-11
AU528060B2 (en) 1983-04-14
ATA134580A (de) 1981-11-15
JPS55127347A (en) 1980-10-02
KR840000103B1 (ko) 1984-02-11
IE49552B1 (en) 1985-10-30
PH14749A (en) 1981-11-20
IL59557A (en) 1983-10-31
DE3060611D1 (en) 1982-08-19
GR68036B (xx) 1981-10-27
SU940645A3 (ru) 1982-06-30
CH644094A5 (fr) 1984-07-13
ES8201525A1 (es) 1981-12-16
LU82237A1 (fr) 1980-06-06
FR2451363B1 (xx) 1983-01-14
CA1144926A (en) 1983-04-19
AU5630280A (en) 1980-09-18
IL59557A0 (en) 1980-06-30
ES497210A0 (es) 1981-12-16
IT8020503A0 (it) 1980-03-11
ES489469A0 (es) 1981-05-16
FI800736A (fi) 1980-09-13

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