CS205028B2 - Method of producing glucosamine derivatives - Google Patents

Method of producing glucosamine derivatives Download PDF

Info

Publication number
CS205028B2
CS205028B2 CS768063A CS28579A CS205028B2 CS 205028 B2 CS205028 B2 CS 205028B2 CS 768063 A CS768063 A CS 768063A CS 28579 A CS28579 A CS 28579A CS 205028 B2 CS205028 B2 CS 205028B2
Authority
CS
Czechoslovakia
Prior art keywords
acid
group
hydrogen
compounds
deoxy
Prior art date
Application number
CS768063A
Other languages
Czech (cs)
English (en)
Inventor
Gerhard Baschang
Albert Hartmann
Jaroslav Stanek
Alex Sele
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of CS205028B2 publication Critical patent/CS205028B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CS768063A 1975-12-10 1976-12-09 Method of producing glucosamine derivatives CS205028B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1604275A CH613709A5 (en) 1975-12-10 1975-12-10 Process for the preparation of glucosamine derivatives

Publications (1)

Publication Number Publication Date
CS205028B2 true CS205028B2 (en) 1981-04-30

Family

ID=4414012

Family Applications (4)

Application Number Title Priority Date Filing Date
CS768063A CS205026B2 (en) 1975-12-10 1976-12-09 Method of producing glocosamine derivatives
CS768063A CS205028B2 (en) 1975-12-10 1976-12-09 Method of producing glucosamine derivatives
CS768063A CS205027B2 (en) 1975-12-10 1976-12-09 Method of producing glucosamine derivatives
CS768063A CS205025B2 (en) 1975-12-10 1976-12-09 Process for preparing derivatives of glukosamine

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CS768063A CS205026B2 (en) 1975-12-10 1976-12-09 Method of producing glocosamine derivatives

Family Applications After (2)

Application Number Title Priority Date Filing Date
CS768063A CS205027B2 (en) 1975-12-10 1976-12-09 Method of producing glucosamine derivatives
CS768063A CS205025B2 (en) 1975-12-10 1976-12-09 Process for preparing derivatives of glukosamine

Country Status (30)

Country Link
JP (1) JPS5273820A (sv)
AR (2) AR224091A1 (sv)
AT (1) AT365607B (sv)
AU (1) AU508764B2 (sv)
BE (1) BE849214A (sv)
CA (1) CA1262400A (sv)
CH (2) CH613709A5 (sv)
CS (4) CS205026B2 (sv)
DD (1) DD129781A5 (sv)
DE (1) DE2655500A1 (sv)
DK (1) DK154654C (sv)
ES (2) ES454118A1 (sv)
FI (1) FI64164C (sv)
FR (1) FR2361902A1 (sv)
GB (1) GB1570625A (sv)
GR (1) GR61647B (sv)
HK (1) HK32883A (sv)
HU (1) HU177970B (sv)
IE (1) IE44190B1 (sv)
IL (1) IL51076A (sv)
MY (1) MY8400123A (sv)
NL (1) NL7613666A (sv)
NO (1) NO144850C (sv)
NZ (1) NZ182837A (sv)
PL (4) PL110787B1 (sv)
PT (1) PT65946B (sv)
SE (1) SE445923B (sv)
SG (1) SG11083G (sv)
SU (3) SU660589A3 (sv)
ZA (1) ZA767333B (sv)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
US4370265A (en) * 1974-10-22 1983-01-25 Agence Nationale De Valorisation Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
GB1571133A (en) * 1976-04-26 1980-07-09 Syntex Inc Immuniological adjuvant peptidoglycans compounds and methods of preparation thereof
DE2862107D1 (en) 1977-12-02 1982-11-18 Takeda Chemical Industries Ltd Glucosamine-peptide derivatives and their pharmaceutical compositions
US4397844A (en) * 1978-02-24 1983-08-09 Ciba-Geigy Corporation Antigen derivatives and processes for their preparation
CA1138436A (en) * 1978-02-24 1982-12-28 Gerhard Baschang Process for the manufacture of novel antigens
FR2442241A2 (fr) * 1978-03-20 1980-06-20 Anvar Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes
FR2420545A1 (fr) * 1978-03-20 1979-10-19 Anvar Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques
FR2428050A1 (fr) * 1978-06-05 1980-01-04 Anvar Oligomeres de composes du type muramyl-peptide et medicaments les contenant
FR2428051A1 (fr) * 1978-06-05 1980-01-04 Anvar Nouveaux composes du type muramyl-peptide et medicaments les contenant
FR2446292A1 (fr) * 1979-01-12 1980-08-08 Anvar Muramyl-peptides fixes sur polymeres peptidiques et medicaments les contenant
US4256735A (en) 1979-01-29 1981-03-17 Merck & Co., Inc. Immunologically active dipeptidyl saccharides and methods of preparation
FR2449697A1 (fr) 1979-02-20 1980-09-19 Anvar Nouveaux muramyl-peptides substitues sur un azote peptidique et medicaments les contenant
JPS55111499A (en) * 1979-02-21 1980-08-28 Takeda Chem Ind Ltd Glucosamine derivative and its preparation
JPS5618996A (en) * 1979-06-21 1981-02-23 Dai Ichi Seiyaku Co Ltd Muramyldipeptide derivative
FI75578C (sv) 1979-07-25 1988-07-11 Ciba Geigy Ag Analogiförfarande för framställning av farmakologiskt verkande lipofil a fosfatidylmuramylpeptider.
JPS5649396A (en) * 1979-09-28 1981-05-02 Dai Ichi Seiyaku Co Ltd Novel muramyldipeptide derivative
EP0026746B1 (de) * 1979-10-02 1985-04-10 Ciba-Geigy Ag Kombinationspräparate zur Anwendung in einem Verfahren zur Steigerung der Wirkung von Antibiotika, antibiotische Präparate mit gesteigerter Wirksamkeit und Verfahren zu deren Herstellung
FI803077A (fi) 1979-10-12 1981-04-13 Ciba Geigy Ag Foerfarande foer framstaellning av myramylpeptider
US4409209A (en) * 1979-10-12 1983-10-11 Ciba-Geigy Corporation Novel phosphorylmuramyl peptides and processes for the manufacture thereof
US4406889A (en) * 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
US4368190A (en) * 1980-04-17 1983-01-11 Merck & Co., Inc. Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
US4310514A (en) 1980-05-05 1982-01-12 Merck & Co., Inc. Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose derivatives and methods of preparation
EP0056560A1 (de) * 1981-01-19 1982-07-28 Ciba-Geigy Ag Antibiotische Präparate mit gesteigerter Wirksamkeit, Verfahren zu deren Herstellung und Verfahren zur Steigerung der antibiotischen Wirkung von Antibiotika
GR78246B (sv) * 1981-01-23 1984-09-26 Ciba Geigy Ag
JPS6042398A (ja) * 1983-08-18 1985-03-06 Toshiyuki Hamaoka ムラミルジペプチド活性エステル誘導体
EP0541486A1 (de) * 1991-11-07 1993-05-12 Ciba-Geigy Ag Polycyclische Konjugate
WO2006118327A1 (ja) * 2005-04-27 2006-11-09 Oxygenix Co Ltd カチオン性アミノ酸型脂質
WO2016138286A1 (en) 2015-02-26 2016-09-01 Stc.Unm Irgm and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy
US10927147B2 (en) 2015-12-10 2021-02-23 Bharat Biotech International Limited Muramyl peptide derivative compound, synthesis and uses thereof
US10576147B2 (en) * 2015-12-15 2020-03-03 Bharat Biotech International Limited Muramyl peptide derivative compound, synthesis and uses thereof
MX2020002010A (es) 2017-08-21 2020-07-13 Celgene Corp Procesos para la preparacion de 4,5-diamino-5-oxopentanoato de (s)-terc-butilo.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents

Also Published As

Publication number Publication date
AR220686A1 (es) 1980-11-28
FI64164B (fi) 1983-06-30
ZA767333B (en) 1977-11-30
DK154654C (da) 1989-05-08
CH613709A5 (en) 1979-10-15
SU747430A3 (ru) 1980-07-23
FR2361902B1 (sv) 1980-11-07
DK552476A (da) 1977-06-11
IE44190B1 (en) 1981-09-09
SG11083G (en) 1983-09-16
SE7613851L (sv) 1977-06-11
DD129781A5 (de) 1978-02-08
PL110353B1 (en) 1980-07-31
PT65946B (en) 1978-06-14
FR2361902A1 (fr) 1978-03-17
PL194291A1 (pl) 1978-10-23
MY8400123A (en) 1984-12-31
AT365607B (de) 1982-02-10
NL7613666A (nl) 1977-06-14
DE2655500C2 (sv) 1988-12-22
FI763541A (sv) 1977-06-11
ATA909276A (de) 1981-06-15
PL110787B1 (en) 1980-07-31
ES454118A1 (es) 1978-03-01
NO144850C (no) 1981-11-25
PL110794B1 (en) 1980-07-31
HK32883A (en) 1983-09-02
NZ182837A (en) 1978-07-28
CS205025B2 (en) 1981-04-30
CS205027B2 (en) 1981-04-30
CS205026B2 (en) 1981-04-30
DE2655500A1 (de) 1977-06-23
AR224091A1 (es) 1981-10-30
DK154654B (da) 1988-12-05
IL51076A (en) 1980-09-16
FI64164C (fi) 1983-10-10
IE44190L (en) 1977-06-10
CA1262400A (en) 1989-10-17
BE849214A (fr) 1977-06-09
JPS638118B2 (sv) 1988-02-19
PL112672B1 (en) 1980-10-31
IL51076A0 (en) 1977-02-28
GB1570625A (en) 1980-07-02
GR61647B (en) 1978-12-05
AU508764B2 (en) 1980-04-03
JPS5273820A (en) 1977-06-21
SU660589A3 (ru) 1979-04-30
HU177970B (en) 1982-02-28
ES465514A1 (es) 1978-09-16
SE445923B (sv) 1986-07-28
AU2042276A (en) 1978-06-15
PT65946A (en) 1977-01-01
SU1060118A3 (ru) 1983-12-07
CH614718A5 (en) 1979-12-14
NO144850B (no) 1981-08-17
NO764191L (sv) 1977-06-13

Similar Documents

Publication Publication Date Title
CS205028B2 (en) Method of producing glucosamine derivatives
FI75578B (fi) Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider.
AU740663B2 (en) Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
US6355257B1 (en) Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
EP0015468B1 (en) 6-deoxyglucosamine-peptide derivatives, their production and use
HU185283B (en) Process for producing new phosphoryl-muramyl-peptides
US4368190A (en) Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
EP0041896B1 (en) Immunologically active dipeptidyl 2-amino-1,2-dideoxy-d-glucose derivatives and methods of preparation
FI72733C (sv) Förfarande för framställning av farmakologiskt verkande glukosderivat samt mellanprodukter använda vid förfarandet.
EP0039637B1 (en) Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-d-glucofuranose derivatives and methods of preparation
US4868155A (en) Dipeptidyl 4-0-,6-0-acyl-2-amino-2-deoxy-D-glucose compositions and methods of use in AIDS-immunocompromised human hosts
EP0014159B1 (en) Immunologically active dipeptidyl saccharides and methods of preparation
EP0018901B1 (en) Immunologically active peptidyl disaccharides, methods of preparation and vaccine
US4377570A (en) Immunologically active dipeptidyl saccharides and methods of preparation
EP0118364B1 (en) Immunostimulatory dipeptidyl d-glucose derivatives and methods of preparation
KR840001687B1 (ko) 포스포릴 무라밀 펩타이드의 제조방법