AU2042276A - Glucosamine derivatives - Google Patents

Glucosamine derivatives

Info

Publication number
AU2042276A
AU2042276A AU20422/76A AU2042276A AU2042276A AU 2042276 A AU2042276 A AU 2042276A AU 20422/76 A AU20422/76 A AU 20422/76A AU 2042276 A AU2042276 A AU 2042276A AU 2042276 A AU2042276 A AU 2042276A
Authority
AU
Australia
Prior art keywords
glucosamine derivatives
glucosamine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU20422/76A
Other versions
AU508764B2 (en
Inventor
G. Hartmann A. Stanek J. and Sele A Haichang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of AU2042276A publication Critical patent/AU2042276A/en
Application granted granted Critical
Publication of AU508764B2 publication Critical patent/AU508764B2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU20422/76A 1975-12-10 1976-12-09 Glucosamine derivatives Expired AU508764B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CHCH16042/75 1975-12-10
CH1604275A CH613709A5 (en) 1975-12-10 1975-12-10 Process for the preparation of glucosamine derivatives

Publications (2)

Publication Number Publication Date
AU2042276A true AU2042276A (en) 1978-06-15
AU508764B2 AU508764B2 (en) 1980-04-03

Family

ID=4414012

Family Applications (1)

Application Number Title Priority Date Filing Date
AU20422/76A Expired AU508764B2 (en) 1975-12-10 1976-12-09 Glucosamine derivatives

Country Status (30)

Country Link
JP (1) JPS5273820A (en)
AR (2) AR224091A1 (en)
AT (1) AT365607B (en)
AU (1) AU508764B2 (en)
BE (1) BE849214A (en)
CA (1) CA1262400A (en)
CH (2) CH613709A5 (en)
CS (4) CS205028B2 (en)
DD (1) DD129781A5 (en)
DE (1) DE2655500A1 (en)
DK (1) DK154654C (en)
ES (2) ES454118A1 (en)
FI (1) FI64164C (en)
FR (1) FR2361902A1 (en)
GB (1) GB1570625A (en)
GR (1) GR61647B (en)
HK (1) HK32883A (en)
HU (1) HU177970B (en)
IE (1) IE44190B1 (en)
IL (1) IL51076A (en)
MY (1) MY8400123A (en)
NL (1) NL7613666A (en)
NO (1) NO144850C (en)
NZ (1) NZ182837A (en)
PL (4) PL112672B1 (en)
PT (1) PT65946B (en)
SE (1) SE445923B (en)
SG (1) SG11083G (en)
SU (3) SU660589A3 (en)
ZA (1) ZA767333B (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
US4370265A (en) * 1974-10-22 1983-01-25 Agence Nationale De Valorisation Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
CH636887A5 (en) * 1976-04-26 1983-06-30 Syntex Inc Process for the preparation of novel immunological adjuvant compounds
DE2862107D1 (en) 1977-12-02 1982-11-18 Takeda Chemical Industries Ltd Glucosamine-peptide derivatives and their pharmaceutical compositions
CA1138436A (en) * 1978-02-24 1982-12-28 Gerhard Baschang Process for the manufacture of novel antigens
US4397844A (en) * 1978-02-24 1983-08-09 Ciba-Geigy Corporation Antigen derivatives and processes for their preparation
FR2442241A2 (en) * 1978-03-20 1980-06-20 Anvar NOVEL ESTER COMPOUNDS OF MURAMYL-PEPTIDE, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, IN PARTICULAR IN THE FORM OF LIPOSOMES
FR2420545A1 (en) * 1978-03-20 1979-10-19 Anvar NEW ESTERS OF N-ACETYL-MURAMYL-AMINOACYL-GLUTAMIC ACID OR SUBSTITUTION DERIVATIVES THEREOF WITH ANTI-INFECTIOUS PROPERTIES AND / OR IMMUNOLOGICAL ADJUVANTS
FR2428051A1 (en) * 1978-06-05 1980-01-04 Anvar NOVEL MURAMYL-PEPTIDE COMPOUNDS AND MEDICAMENTS CONTAINING THEM
FR2428050A1 (en) * 1978-06-05 1980-01-04 Anvar OLIGOMERS OF MURAMYL-PEPTIDE COMPOUNDS AND DRUGS CONTAINING THEM
FR2446292A1 (en) * 1979-01-12 1980-08-08 Anvar MURAMYL-PEPTIDES FIXED ON PEPTIDE POLYMERS AND MEDICAMENTS CONTAINING THEM
US4256735A (en) 1979-01-29 1981-03-17 Merck & Co., Inc. Immunologically active dipeptidyl saccharides and methods of preparation
FR2449697A1 (en) 1979-02-20 1980-09-19 Anvar NOVEL MURAMYL-PEPTIDES SUBSTITUTED ON PEPTIDE NITROGEN AND MEDICAMENTS CONTAINING THEM
JPS55111499A (en) * 1979-02-21 1980-08-28 Takeda Chem Ind Ltd Glucosamine derivative and its preparation
JPS5618996A (en) * 1979-06-21 1981-02-23 Dai Ichi Seiyaku Co Ltd Muramyldipeptide derivative
FI75578C (en) 1979-07-25 1988-07-11 Ciba Geigy Ag Analogous procedure for the preparation of pharmacologically acting lipophilic a phosphatidylmuramyl peptides.
JPS5649396A (en) * 1979-09-28 1981-05-02 Dai Ichi Seiyaku Co Ltd Novel muramyldipeptide derivative
DE3070457D1 (en) * 1979-10-02 1985-05-15 Ciba Geigy Ag Combinatory compositions for use in a method for enhancing the activity of antibiotics, antibiotic preparations having enhanced activity and process for their production
FI803077A (en) 1979-10-12 1981-04-13 Ciba Geigy Ag FOERFARANDE FOER FRAMSTAELLNING AV MYRAMYLPEPTIDER
US4409209A (en) * 1979-10-12 1983-10-11 Ciba-Geigy Corporation Novel phosphorylmuramyl peptides and processes for the manufacture thereof
US4406889A (en) * 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
US4368190A (en) * 1980-04-17 1983-01-11 Merck & Co., Inc. Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
US4310514A (en) 1980-05-05 1982-01-12 Merck & Co., Inc. Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose derivatives and methods of preparation
EP0056560A1 (en) * 1981-01-19 1982-07-28 Ciba-Geigy Ag Active antibiotic compositions, process for their manufacture and process for the antibiotic activity of antibiotics
GR78246B (en) * 1981-01-23 1984-09-26 Ciba Geigy Ag
JPS6042398A (en) * 1983-08-18 1985-03-06 Toshiyuki Hamaoka Muramyldipeptide active ester derivative
EP0541486A1 (en) * 1991-11-07 1993-05-12 Ciba-Geigy Ag Polycyclic conjugates
US7838685B2 (en) 2005-04-27 2010-11-23 Shinji Takeoka Cationic amino acid type lipid
US10610564B2 (en) 2015-02-26 2020-04-07 Stc.Unm IRGM and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy
WO2017098529A1 (en) 2015-12-10 2017-06-15 Bharat Biotech International Limited Novel muramyl peptide derivative compound, synthesis and uses thereof
US10576147B2 (en) * 2015-12-15 2020-03-03 Bharat Biotech International Limited Muramyl peptide derivative compound, synthesis and uses thereof
CA3072735A1 (en) 2017-08-21 2019-02-28 Celgene Corporation Processes for the preparation of (s)-tert-butyl 4,5-diamino-5-oxopentanoate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents

Also Published As

Publication number Publication date
ZA767333B (en) 1977-11-30
IE44190L (en) 1977-06-10
DE2655500A1 (en) 1977-06-23
DK154654C (en) 1989-05-08
FI763541A (en) 1977-06-11
ES465514A1 (en) 1978-09-16
IL51076A0 (en) 1977-02-28
FR2361902A1 (en) 1978-03-17
SE445923B (en) 1986-07-28
PT65946B (en) 1978-06-14
DD129781A5 (en) 1978-02-08
NO144850C (en) 1981-11-25
NO764191L (en) 1977-06-13
CS205027B2 (en) 1981-04-30
CS205028B2 (en) 1981-04-30
SE7613851L (en) 1977-06-11
FR2361902B1 (en) 1980-11-07
MY8400123A (en) 1984-12-31
JPS5273820A (en) 1977-06-21
AT365607B (en) 1982-02-10
ATA909276A (en) 1981-06-15
BE849214A (en) 1977-06-09
AR220686A1 (en) 1980-11-28
IE44190B1 (en) 1981-09-09
NZ182837A (en) 1978-07-28
HK32883A (en) 1983-09-02
DK552476A (en) 1977-06-11
AU508764B2 (en) 1980-04-03
PT65946A (en) 1977-01-01
PL194291A1 (en) 1978-10-23
DE2655500C2 (en) 1988-12-22
JPS638118B2 (en) 1988-02-19
SU660589A3 (en) 1979-04-30
PL112672B1 (en) 1980-10-31
ES454118A1 (en) 1978-03-01
PL110787B1 (en) 1980-07-31
PL110353B1 (en) 1980-07-31
NO144850B (en) 1981-08-17
IL51076A (en) 1980-09-16
CH614718A5 (en) 1979-12-14
AR224091A1 (en) 1981-10-30
CA1262400A (en) 1989-10-17
HU177970B (en) 1982-02-28
FI64164B (en) 1983-06-30
SG11083G (en) 1983-09-16
PL110794B1 (en) 1980-07-31
CS205025B2 (en) 1981-04-30
CH613709A5 (en) 1979-10-15
CS205026B2 (en) 1981-04-30
NL7613666A (en) 1977-06-14
FI64164C (en) 1983-10-10
SU1060118A3 (en) 1983-12-07
DK154654B (en) 1988-12-05
GB1570625A (en) 1980-07-02
GR61647B (en) 1978-12-05
SU747430A3 (en) 1980-07-23

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