JPS5273820A - Glucosamine derivative and its method of manufacturing - Google Patents

Glucosamine derivative and its method of manufacturing

Info

Publication number
JPS5273820A
JPS5273820A JP51147903A JP14790376A JPS5273820A JP S5273820 A JPS5273820 A JP S5273820A JP 51147903 A JP51147903 A JP 51147903A JP 14790376 A JP14790376 A JP 14790376A JP S5273820 A JPS5273820 A JP S5273820A
Authority
JP
Japan
Prior art keywords
manufacturing
glucosamine derivative
glucosamine
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP51147903A
Other languages
Japanese (ja)
Other versions
JPS638118B2 (en
Inventor
Basuhangu Geruharuto
Harutoman Aruberuto
Sutanetsuku Yarosurafu
Zeere Aretsukusu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of JPS5273820A publication Critical patent/JPS5273820A/en
Publication of JPS638118B2 publication Critical patent/JPS638118B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP51147903A 1975-12-10 1976-12-10 Glucosamine derivative and its method of manufacturing Granted JPS5273820A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1604275A CH613709A5 (en) 1975-12-10 1975-12-10 Process for the preparation of glucosamine derivatives

Publications (2)

Publication Number Publication Date
JPS5273820A true JPS5273820A (en) 1977-06-21
JPS638118B2 JPS638118B2 (en) 1988-02-19

Family

ID=4414012

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51147903A Granted JPS5273820A (en) 1975-12-10 1976-12-10 Glucosamine derivative and its method of manufacturing

Country Status (30)

Country Link
JP (1) JPS5273820A (en)
AR (2) AR224091A1 (en)
AT (1) AT365607B (en)
AU (1) AU508764B2 (en)
BE (1) BE849214A (en)
CA (1) CA1262400A (en)
CH (2) CH613709A5 (en)
CS (4) CS205026B2 (en)
DD (1) DD129781A5 (en)
DE (1) DE2655500A1 (en)
DK (1) DK154654C (en)
ES (2) ES454118A1 (en)
FI (1) FI64164C (en)
FR (1) FR2361902A1 (en)
GB (1) GB1570625A (en)
GR (1) GR61647B (en)
HK (1) HK32883A (en)
HU (1) HU177970B (en)
IE (1) IE44190B1 (en)
IL (1) IL51076A (en)
MY (1) MY8400123A (en)
NL (1) NL7613666A (en)
NO (1) NO144850C (en)
NZ (1) NZ182837A (en)
PL (4) PL110787B1 (en)
PT (1) PT65946B (en)
SE (1) SE445923B (en)
SG (1) SG11083G (en)
SU (3) SU660589A3 (en)
ZA (1) ZA767333B (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54141718A (en) * 1978-02-24 1979-11-05 Ciba Geigy Ag Novel antigen derivative and its manufacture
JPS55392A (en) * 1978-06-05 1980-01-05 Anvar Muramyllpeptide type novel compounds and drug containing them
JPS55500167A (en) * 1978-03-20 1980-03-27
JPS55102599A (en) * 1979-01-29 1980-08-05 Merck & Co Inc Immunologically active dipertidyl saccharides and manufacture
JPS5649396A (en) * 1979-09-28 1981-05-02 Dai Ichi Seiyaku Co Ltd Novel muramyldipeptide derivative
JPS56128794A (en) * 1980-02-15 1981-10-08 Ciba Geigy Ag Aldohexose derivatives, their manufacture and medicine containing them
JPS56164196A (en) * 1980-04-17 1981-12-17 Merck & Co Inc Immunologically active dipeptidyl-4-0-, 6-0-acyl-2-amino-2-deoxy-d-glucose derivative and manufacture
WO2006118327A1 (en) * 2005-04-27 2006-11-09 Oxygenix Co Ltd Cationic amino acid type lipid

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
US4370265A (en) * 1974-10-22 1983-01-25 Agence Nationale De Valorisation Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
GB1571133A (en) * 1976-04-26 1980-07-09 Syntex Inc Immuniological adjuvant peptidoglycans compounds and methods of preparation thereof
DE2862107D1 (en) 1977-12-02 1982-11-18 Takeda Chemical Industries Ltd Glucosamine-peptide derivatives and their pharmaceutical compositions
US4397844A (en) * 1978-02-24 1983-08-09 Ciba-Geigy Corporation Antigen derivatives and processes for their preparation
FR2442241A2 (en) * 1978-03-20 1980-06-20 Anvar NOVEL ESTER COMPOUNDS OF MURAMYL-PEPTIDE, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, IN PARTICULAR IN THE FORM OF LIPOSOMES
FR2428050A1 (en) * 1978-06-05 1980-01-04 Anvar OLIGOMERS OF MURAMYL-PEPTIDE COMPOUNDS AND DRUGS CONTAINING THEM
FR2446292A1 (en) * 1979-01-12 1980-08-08 Anvar MURAMYL-PEPTIDES FIXED ON PEPTIDE POLYMERS AND MEDICAMENTS CONTAINING THEM
FR2449697A1 (en) 1979-02-20 1980-09-19 Anvar NOVEL MURAMYL-PEPTIDES SUBSTITUTED ON PEPTIDE NITROGEN AND MEDICAMENTS CONTAINING THEM
JPS55111499A (en) * 1979-02-21 1980-08-28 Takeda Chem Ind Ltd Glucosamine derivative and its preparation
JPS5618996A (en) * 1979-06-21 1981-02-23 Dai Ichi Seiyaku Co Ltd Muramyldipeptide derivative
FI75578C (en) * 1979-07-25 1988-07-11 Ciba Geigy Ag Analogous procedure for the preparation of pharmacologically acting lipophilic a phosphatidylmuramyl peptides.
EP0026746B1 (en) * 1979-10-02 1985-04-10 Ciba-Geigy Ag Combinatory compositions for use in a method for enhancing the activity of antibiotics, antibiotic preparations having enhanced activity and process for their production
US4409209A (en) * 1979-10-12 1983-10-11 Ciba-Geigy Corporation Novel phosphorylmuramyl peptides and processes for the manufacture thereof
FI803077A (en) 1979-10-12 1981-04-13 Ciba Geigy Ag FOERFARANDE FOER FRAMSTAELLNING AV MYRAMYLPEPTIDER
US4310514A (en) 1980-05-05 1982-01-12 Merck & Co., Inc. Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose derivatives and methods of preparation
EP0056560A1 (en) * 1981-01-19 1982-07-28 Ciba-Geigy Ag Active antibiotic compositions, process for their manufacture and process for the antibiotic activity of antibiotics
GR78246B (en) * 1981-01-23 1984-09-26 Ciba Geigy Ag
JPS6042398A (en) * 1983-08-18 1985-03-06 Toshiyuki Hamaoka Muramyldipeptide active ester derivative
EP0541486A1 (en) * 1991-11-07 1993-05-12 Ciba-Geigy Ag Polycyclic conjugates
US10610564B2 (en) 2015-02-26 2020-04-07 Stc.Unm IRGM and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy
ES2930246T3 (en) * 2015-12-10 2022-12-09 Bharat Biotech Int Ltd New compound derived from muramyl peptide, synthesis and uses thereof
EP3389643B1 (en) * 2015-12-15 2023-05-03 Bharat Biotech International Limited Novel muramyl peptide derivative compound, synthesis and uses thereof
WO2019040109A1 (en) 2017-08-21 2019-02-28 Celgene Corporation Processes for preparation of (s)-tert-butyl 4,5-diamino-5-oxopentanoate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54141718A (en) * 1978-02-24 1979-11-05 Ciba Geigy Ag Novel antigen derivative and its manufacture
JPH0130809B2 (en) * 1978-02-24 1989-06-22 Ciba Geigy
JPS55500167A (en) * 1978-03-20 1980-03-27
JPS55392A (en) * 1978-06-05 1980-01-05 Anvar Muramyllpeptide type novel compounds and drug containing them
JPH0233720B2 (en) * 1978-06-05 1990-07-30 Anbaaru Ajansu Nashionaru Do Barorizashion Do Ra Rusherushu
JPS55102599A (en) * 1979-01-29 1980-08-05 Merck & Co Inc Immunologically active dipertidyl saccharides and manufacture
JPS5649396A (en) * 1979-09-28 1981-05-02 Dai Ichi Seiyaku Co Ltd Novel muramyldipeptide derivative
JPS6312879B2 (en) * 1979-09-28 1988-03-23 Daiichi Seiyaku Co
JPS56128794A (en) * 1980-02-15 1981-10-08 Ciba Geigy Ag Aldohexose derivatives, their manufacture and medicine containing them
JPS56164196A (en) * 1980-04-17 1981-12-17 Merck & Co Inc Immunologically active dipeptidyl-4-0-, 6-0-acyl-2-amino-2-deoxy-d-glucose derivative and manufacture
WO2006118327A1 (en) * 2005-04-27 2006-11-09 Oxygenix Co Ltd Cationic amino acid type lipid
US7838685B2 (en) 2005-04-27 2010-11-23 Shinji Takeoka Cationic amino acid type lipid

Also Published As

Publication number Publication date
IL51076A0 (en) 1977-02-28
MY8400123A (en) 1984-12-31
AU508764B2 (en) 1980-04-03
CS205026B2 (en) 1981-04-30
NO764191L (en) 1977-06-13
JPS638118B2 (en) 1988-02-19
CS205027B2 (en) 1981-04-30
HU177970B (en) 1982-02-28
DK154654C (en) 1989-05-08
CH613709A5 (en) 1979-10-15
ES465514A1 (en) 1978-09-16
DK154654B (en) 1988-12-05
ZA767333B (en) 1977-11-30
CA1262400A (en) 1989-10-17
PL110353B1 (en) 1980-07-31
AT365607B (en) 1982-02-10
AR224091A1 (en) 1981-10-30
CH614718A5 (en) 1979-12-14
DK552476A (en) 1977-06-11
ES454118A1 (en) 1978-03-01
FI64164B (en) 1983-06-30
FI64164C (en) 1983-10-10
PL194291A1 (en) 1978-10-23
DE2655500A1 (en) 1977-06-23
IL51076A (en) 1980-09-16
FR2361902B1 (en) 1980-11-07
SE7613851L (en) 1977-06-11
SE445923B (en) 1986-07-28
NO144850C (en) 1981-11-25
CS205028B2 (en) 1981-04-30
IE44190B1 (en) 1981-09-09
AR220686A1 (en) 1980-11-28
SU1060118A3 (en) 1983-12-07
PT65946A (en) 1977-01-01
HK32883A (en) 1983-09-02
CS205025B2 (en) 1981-04-30
SU747430A3 (en) 1980-07-23
NL7613666A (en) 1977-06-14
ATA909276A (en) 1981-06-15
PT65946B (en) 1978-06-14
PL112672B1 (en) 1980-10-31
NZ182837A (en) 1978-07-28
IE44190L (en) 1977-06-10
SU660589A3 (en) 1979-04-30
SG11083G (en) 1983-09-16
FR2361902A1 (en) 1978-03-17
DD129781A5 (en) 1978-02-08
FI763541A (en) 1977-06-11
GB1570625A (en) 1980-07-02
GR61647B (en) 1978-12-05
PL110787B1 (en) 1980-07-31
PL110794B1 (en) 1980-07-31
NO144850B (en) 1981-08-17
AU2042276A (en) 1978-06-15
DE2655500C2 (en) 1988-12-22
BE849214A (en) 1977-06-09

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