DE2655500A1 - GLUCOSAMINE DERIVATIVES AND A METHOD FOR THE PREPARATION - Google Patents

GLUCOSAMINE DERIVATIVES AND A METHOD FOR THE PREPARATION

Info

Publication number
DE2655500A1
DE2655500A1 DE19762655500 DE2655500A DE2655500A1 DE 2655500 A1 DE2655500 A1 DE 2655500A1 DE 19762655500 DE19762655500 DE 19762655500 DE 2655500 A DE2655500 A DE 2655500A DE 2655500 A1 DE2655500 A1 DE 2655500A1
Authority
DE
Germany
Prior art keywords
glucosamine derivatives
glucosamine
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19762655500
Other languages
German (de)
Other versions
DE2655500C2 (en
Inventor
Gerhard Dr Baschang
Albert Dr Hartmann
Jaroslav Dr Stanek
Alex Sele
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ciba Geigy AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CH1604275A priority Critical patent/CH613709A5/en
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of DE2655500A1 publication Critical patent/DE2655500A1/en
Application granted granted Critical
Publication of DE2655500C2 publication Critical patent/DE2655500C2/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
DE2655500A 1975-12-10 1976-12-08 Expired DE2655500C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CH1604275A CH613709A5 (en) 1975-12-10 1975-12-10 Process for the preparation of glucosamine derivatives

Publications (2)

Publication Number Publication Date
DE2655500A1 true DE2655500A1 (en) 1977-06-23
DE2655500C2 DE2655500C2 (en) 1988-12-22

Family

ID=4414012

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2655500A Expired DE2655500C2 (en) 1975-12-10 1976-12-08

Country Status (30)

Country Link
JP (1) JPS638118B2 (en)
AR (2) AR224091A1 (en)
AT (1) AT365607B (en)
AU (1) AU508764B2 (en)
BE (1) BE849214A (en)
CA (1) CA1262400A (en)
CH (2) CH613709A5 (en)
CS (4) CS205028B2 (en)
DD (1) DD129781A5 (en)
DE (1) DE2655500C2 (en)
DK (1) DK154654C (en)
ES (2) ES454118A1 (en)
FI (1) FI64164C (en)
FR (1) FR2361902B1 (en)
GB (1) GB1570625A (en)
GR (1) GR61647B (en)
HK (1) HK32883A (en)
HU (1) HU177970B (en)
IE (1) IE44190B1 (en)
IL (1) IL51076A (en)
MY (1) MY8400123A (en)
NL (1) NL7613666A (en)
NO (1) NO144850C (en)
NZ (1) NZ182837A (en)
PL (4) PL110353B1 (en)
PT (1) PT65946B (en)
SE (1) SE445923B (en)
SG (1) SG11083G (en)
SU (3) SU660589A3 (en)
ZA (1) ZA7607333B (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2718010A1 (en) * 1976-04-26 1977-11-10 Syntex Inc NEW IMMUNOLOGICAL ADJUVANIC COMPOUNDS AND METHODS OF PREPARING THE SAME
US4235771A (en) * 1973-10-23 1980-11-25 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
EP0026746A1 (en) * 1979-10-02 1981-04-08 Ciba-Geigy Ag Combinatory compositions for use in a method for enhancing the activity of antibiotics, antibiotic preparations having enhanced activity and process for their production
EP0056560A1 (en) * 1981-01-19 1982-07-28 Ciba-Geigy Ag Active antibiotic compositions, process for their manufacture and process for the antibiotic activity of antibiotics
EP0056992A1 (en) * 1981-01-23 1982-08-04 Ciba-Geigy Ag Phosphorylated derivatives, pharmaceutical compositions containing such derivatives, and their use
US4370265A (en) * 1974-10-22 1983-01-25 Agence Nationale De Valorisation Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
US4401659A (en) * 1979-01-12 1983-08-30 Agence National De Valorisation De La Recherche (Anvar) Muramyl-peptides fixed to peptide-polymers and pharmaceutical compositions containing them
US4446128A (en) * 1978-02-24 1984-05-01 Ciba-Geigy Corporation Antigen derivatives and processes for their preparation
US5264431A (en) * 1991-11-07 1993-11-23 Ciba-Geigy Corp. Polycyclic conjugates

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI66878C (en) * 1978-02-24 1984-12-10 Ciba Geigy Ag FOERFARANDE Foer FRAMSTAELLNING AV NYA ANTIGENDERIVAT
FR2442241B2 (en) * 1978-03-20 1983-04-22 Anvar
FR2420545B1 (en) * 1978-03-20 1981-03-27 Anvar
FR2428051B1 (en) * 1978-06-05 1981-12-04 Anvar
FR2428050B1 (en) * 1978-06-05 1981-06-26 Anvar
US4256735A (en) * 1979-01-29 1981-03-17 Merck & Co., Inc. Immunologically active dipeptidyl saccharides and methods of preparation
JPS6244555B2 (en) * 1979-02-21 1987-09-21 Takeda Chemical Industries Ltd
JPS6227079B2 (en) * 1979-06-21 1987-06-12 Daiichi Seiyaku Co
FI75578C (en) * 1979-07-25 1988-07-11 Ciba Geigy Ag Analogous procedure for the preparation of pharmacologically acting lipophilic a phosphatidylmuramyl peptides.
JPS6312879B2 (en) * 1979-09-28 1988-03-23 Daiichi Seiyaku Co
FI803077A (en) * 1979-10-12 1981-04-13 Ciba Geigy Ag Foerfarande foer framstaellning av myramylpeptider
US4409209A (en) * 1979-10-12 1983-10-11 Ciba-Geigy Corporation Novel phosphorylmuramyl peptides and processes for the manufacture thereof
US4406889A (en) * 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
US4368190A (en) * 1980-04-17 1983-01-11 Merck & Co., Inc. Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
JPH0421680B2 (en) * 1983-08-18 1992-04-13 Toshuki Hamaoka
WO2006118327A1 (en) * 2005-04-27 2006-11-09 Oxygenix Co Ltd Cationic amino acid type lipid
US10610564B2 (en) 2015-02-26 2020-04-07 Stc.Unm IRGM and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy
US10927147B2 (en) 2015-12-10 2021-02-23 Bharat Biotech International Limited Muramyl peptide derivative compound, synthesis and uses thereof
EP3389643A4 (en) * 2015-12-15 2019-07-10 Bharat Biotech International Limited Novel muramyl peptide derivative compound, synthesis and uses thereof
JP2020531500A (en) 2017-08-21 2020-11-05 セルジーン コーポレイション (S) -TERT-Butyl 4,5-diamino-5-oxopentanoate preparation process

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2450355A1 (en) * 1973-10-23 1975-05-28 Anvar ADJUVANCES FORMED FROM N-ACYL-MURAMIC ACID DERIVATIVES AND VACCINES CONTAINING THEM

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2450355A1 (en) * 1973-10-23 1975-05-28 Anvar ADJUVANCES FORMED FROM N-ACYL-MURAMIC ACID DERIVATIVES AND VACCINES CONTAINING THEM

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
Biochem. Biophys. Res. Commun. 59, 1974, S.1317-1325 *
C.A., 83, 1975, 161981 *
ibido, 66, 1975, S.1316-1322 *
J. Med. Chem., 9, 1966, S.971-975 *
Z. Immun.-Forsch., 149, 1975, S.341-348 *

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235771A (en) * 1973-10-23 1980-11-25 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
US4323559A (en) * 1973-10-23 1982-04-06 Agencie Nationale De Valorisation De La Recherche (Anvar) Compounds derived from N-acetyl-nor-muramyl-L-alanyl-D-isoglutamic acid and other compounds and biologically active compositions containing such compounds
US4327085A (en) * 1973-10-23 1982-04-27 Agence National De Valorisation De La Recherache (Anvar) Biologically active compositions and methods of use
US4370265A (en) * 1974-10-22 1983-01-25 Agence Nationale De Valorisation Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
DE2718010A1 (en) * 1976-04-26 1977-11-10 Syntex Inc NEW IMMUNOLOGICAL ADJUVANIC COMPOUNDS AND METHODS OF PREPARING THE SAME
US4446128A (en) * 1978-02-24 1984-05-01 Ciba-Geigy Corporation Antigen derivatives and processes for their preparation
US4401659A (en) * 1979-01-12 1983-08-30 Agence National De Valorisation De La Recherche (Anvar) Muramyl-peptides fixed to peptide-polymers and pharmaceutical compositions containing them
EP0026746A1 (en) * 1979-10-02 1981-04-08 Ciba-Geigy Ag Combinatory compositions for use in a method for enhancing the activity of antibiotics, antibiotic preparations having enhanced activity and process for their production
EP0056560A1 (en) * 1981-01-19 1982-07-28 Ciba-Geigy Ag Active antibiotic compositions, process for their manufacture and process for the antibiotic activity of antibiotics
EP0056992A1 (en) * 1981-01-23 1982-08-04 Ciba-Geigy Ag Phosphorylated derivatives, pharmaceutical compositions containing such derivatives, and their use
US5264431A (en) * 1991-11-07 1993-11-23 Ciba-Geigy Corp. Polycyclic conjugates

Also Published As

Publication number Publication date
AR220686A1 (en) 1980-11-28
SU1060118A3 (en) 1983-12-07
SE445923B (en) 1986-07-28
BE849214A1 (en)
SG11083G (en) 1983-09-16
PL110787B1 (en) 1980-07-31
DK154654B (en) 1988-12-05
PT65946B (en) 1978-06-14
AU508764B2 (en) 1980-04-03
CA1262400A (en) 1989-10-17
AR224091A1 (en) 1981-10-30
CH613709A5 (en) 1979-10-15
PL110794B1 (en) 1980-07-31
AU2042276A (en) 1978-06-15
CS205027B2 (en) 1981-04-30
FR2361902A1 (en) 1978-03-17
NZ182837A (en) 1978-07-28
HK32883A (en) 1983-09-02
ES454118A1 (en) 1978-03-01
IE44190B1 (en) 1981-09-09
SU747430A3 (en) 1980-07-23
FI64164B (en) 1983-06-30
PL194291A1 (en) 1978-10-23
FI64164C (en) 1983-10-10
DD129781A5 (en) 1978-02-08
BE849214A (en) 1977-06-09
GB1570625A (en) 1980-07-02
GR61647B (en) 1978-12-05
MY8400123A (en) 1984-12-31
DK154654C (en) 1989-05-08
ATA909276A (en) 1981-06-15
NL7613666A (en) 1977-06-14
NO144850B (en) 1981-08-17
CS205026B2 (en) 1981-04-30
SE7613851L (en) 1977-06-11
JPS638118B2 (en) 1988-02-19
NO764191L (en) 1977-06-13
IL51076D0 (en) 1977-02-28
FI763541A (en) 1977-06-11
NO144850C (en) 1981-11-25
PL112672B1 (en) 1980-10-31
ZA7607333B (en) 1977-11-30
HU177970B (en) 1982-02-28
DK552476A (en) 1977-06-11
CS205025B2 (en) 1981-04-30
CA1262400A1 (en)
JPS5273820A (en) 1977-06-21
CH614718A5 (en) 1979-12-14
CS205028B2 (en) 1981-04-30
PT65946A (en) 1977-01-01
AT365607B (en) 1982-02-10
SU660589A3 (en) 1979-04-30
FR2361902B1 (en) 1980-11-07
IE44190L (en) 1977-06-10
PL110353B1 (en) 1980-07-31
IL51076A (en) 1980-09-16
DE2655500C2 (en) 1988-12-22
ES465514A1 (en) 1978-09-16

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