FR2361902A1 - Derives de la glucosamine et leur procede de fabrication - Google Patents

Derives de la glucosamine et leur procede de fabrication

Info

Publication number
FR2361902A1
FR2361902A1 FR7637091A FR7637091A FR2361902A1 FR 2361902 A1 FR2361902 A1 FR 2361902A1 FR 7637091 A FR7637091 A FR 7637091A FR 7637091 A FR7637091 A FR 7637091A FR 2361902 A1 FR2361902 A1 FR 2361902A1
Authority
FR
France
Prior art keywords
manufacturing process
glucosamine derivatives
glucosamine
derivatives
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7637091A
Other languages
English (en)
Other versions
FR2361902B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of FR2361902A1 publication Critical patent/FR2361902A1/fr
Application granted granted Critical
Publication of FR2361902B1 publication Critical patent/FR2361902B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention concerne des composés chimiques nouveaux et un procédé pour leur fabrication. Ces composés répondent à la formule :
FR7637091A 1975-12-10 1976-12-09 Derives de la glucosamine et leur procede de fabrication Granted FR2361902A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1604275A CH613709A5 (en) 1975-12-10 1975-12-10 Process for the preparation of glucosamine derivatives

Publications (2)

Publication Number Publication Date
FR2361902A1 true FR2361902A1 (fr) 1978-03-17
FR2361902B1 FR2361902B1 (fr) 1980-11-07

Family

ID=4414012

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7637091A Granted FR2361902A1 (fr) 1975-12-10 1976-12-09 Derives de la glucosamine et leur procede de fabrication

Country Status (30)

Country Link
JP (1) JPS5273820A (fr)
AR (2) AR224091A1 (fr)
AT (1) AT365607B (fr)
AU (1) AU508764B2 (fr)
BE (1) BE849214A (fr)
CA (1) CA1262400A (fr)
CH (2) CH613709A5 (fr)
CS (4) CS205025B2 (fr)
DD (1) DD129781A5 (fr)
DE (1) DE2655500A1 (fr)
DK (1) DK154654C (fr)
ES (2) ES454118A1 (fr)
FI (1) FI64164C (fr)
FR (1) FR2361902A1 (fr)
GB (1) GB1570625A (fr)
GR (1) GR61647B (fr)
HK (1) HK32883A (fr)
HU (1) HU177970B (fr)
IE (1) IE44190B1 (fr)
IL (1) IL51076A (fr)
MY (1) MY8400123A (fr)
NL (1) NL7613666A (fr)
NO (1) NO144850C (fr)
NZ (1) NZ182837A (fr)
PL (4) PL112672B1 (fr)
PT (1) PT65946B (fr)
SE (1) SE445923B (fr)
SG (1) SG11083G (fr)
SU (3) SU660589A3 (fr)
ZA (1) ZA767333B (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0004512A1 (fr) * 1978-03-20 1979-10-03 ANVAR Agence Nationale de Valorisation de la Recherche Composés esters de muramyl-peptide et leurs applications dans les compositions pharmaceutiques et réactifs de laboratoire
WO1979000802A1 (fr) * 1978-03-20 1979-10-18 Anvar Nouveaux composes esters de muramyl-peptide et leurs applications dans les compositions pharmaceutiques et reactifs de laboratoire
EP0014159A1 (fr) * 1979-01-29 1980-08-06 Merck & Co. Inc. Dipeptidyl saccharides immunologiquement actifs et méthodes de préparation
EP0014984A1 (fr) * 1979-02-21 1980-09-03 Takeda Chemical Industries, Ltd. Dérivés peptidiques de la glucosamine, leur préparation et leur utilisation
EP0021367A1 (fr) * 1979-06-21 1981-01-07 Daiichi Seiyaku Co., Ltd. Dérivés de muramyldipeptides, procédé pour leur préparation et compositions pharmaceutiques les contenant
EP0025495A1 (fr) * 1979-07-25 1981-03-25 Ciba-Geigy Ag Muramyl peptides à activité lipophyle, procédés pour les préparer et leur utilisation
EP0027258A1 (fr) * 1979-10-12 1981-04-22 Ciba-Geigy Ag Phosphorylmuramyl peptides, procédé pour leur préparation et leur utilisation dans des médicaments
EP0056992A1 (fr) * 1981-01-23 1982-08-04 Ciba-Geigy Ag Dérivés phosphorylés, compositions pharmaceutiques contenant ces dérivés et leur application

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
US4370265A (en) * 1974-10-22 1983-01-25 Agence Nationale De Valorisation Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
CH636887A5 (en) * 1976-04-26 1983-06-30 Syntex Inc Process for the preparation of novel immunological adjuvant compounds
EP0002677B1 (fr) 1977-12-02 1982-10-13 Takeda Chemical Industries, Ltd. Dérivés de glucosamine-peptides et leurs compositions pharmaceutiques
US4397844A (en) * 1978-02-24 1983-08-09 Ciba-Geigy Corporation Antigen derivatives and processes for their preparation
FI66878C (fi) * 1978-02-24 1984-12-10 Ciba Geigy Ag Foerfarande foer framstaellning av nya antigenderivat
FR2428050A1 (fr) * 1978-06-05 1980-01-04 Anvar Oligomeres de composes du type muramyl-peptide et medicaments les contenant
FR2428051A1 (fr) * 1978-06-05 1980-01-04 Anvar Nouveaux composes du type muramyl-peptide et medicaments les contenant
FR2446292A1 (fr) * 1979-01-12 1980-08-08 Anvar Muramyl-peptides fixes sur polymeres peptidiques et medicaments les contenant
FR2449697A1 (fr) 1979-02-20 1980-09-19 Anvar Nouveaux muramyl-peptides substitues sur un azote peptidique et medicaments les contenant
JPS5649396A (en) * 1979-09-28 1981-05-02 Dai Ichi Seiyaku Co Ltd Novel muramyldipeptide derivative
DE3070457D1 (en) * 1979-10-02 1985-05-15 Ciba Geigy Ag Combinatory compositions for use in a method for enhancing the activity of antibiotics, antibiotic preparations having enhanced activity and process for their production
US4409209A (en) * 1979-10-12 1983-10-11 Ciba-Geigy Corporation Novel phosphorylmuramyl peptides and processes for the manufacture thereof
US4406889A (en) * 1980-02-15 1983-09-27 Ciba-Geigy Corporation Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use
US4368190A (en) * 1980-04-17 1983-01-11 Merck & Co., Inc. Immunologically active dipeptidyl 4-O-,6-O-acyl-2-amino-2-deoxy-D-glucose derivatives and methods for their preparation
US4310514A (en) 1980-05-05 1982-01-12 Merck & Co., Inc. Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose derivatives and methods of preparation
EP0056560A1 (fr) * 1981-01-19 1982-07-28 Ciba-Geigy Ag Préparations antibiotiques à effet accru, procédé pour leur obtention et procédé pour augmenter l'effet antibiotique des antibiotiques
JPS6042398A (ja) * 1983-08-18 1985-03-06 Toshiyuki Hamaoka ムラミルジペプチド活性エステル誘導体
EP0541486A1 (fr) * 1991-11-07 1993-05-12 Ciba-Geigy Ag Conjugates polycycliques
RU2181729C1 (ru) * 2000-09-20 2002-04-27 Калюжин Олег Витальевич Производные мурамовой кислоты
WO2006118327A1 (fr) * 2005-04-27 2006-11-09 Oxygenix Co Ltd Lipide de type acide aminé cationique
US10610564B2 (en) 2015-02-26 2020-04-07 Stc.Unm IRGM and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy
WO2017098529A1 (fr) * 2015-12-10 2017-06-15 Bharat Biotech International Limited Nouveau composé dérivé de muramyle, synthèse et utilisations associées
US12134664B2 (en) 2015-12-10 2024-11-05 Bharat Biotech International Ltd. Muramyl peptide derivatives
US10576147B2 (en) * 2015-12-15 2020-03-03 Bharat Biotech International Limited Muramyl peptide derivative compound, synthesis and uses thereof
EP3672939A1 (fr) 2017-08-21 2020-07-01 Celgene Corporation Procédés de préparation de (s)-tert-butyl 4,5-diamino-5-oxopentanoate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186194A (en) * 1973-10-23 1980-01-29 Agence Nationale De Valorisation De La Recherche (Anvar) Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0004512A1 (fr) * 1978-03-20 1979-10-03 ANVAR Agence Nationale de Valorisation de la Recherche Composés esters de muramyl-peptide et leurs applications dans les compositions pharmaceutiques et réactifs de laboratoire
WO1979000802A1 (fr) * 1978-03-20 1979-10-18 Anvar Nouveaux composes esters de muramyl-peptide et leurs applications dans les compositions pharmaceutiques et reactifs de laboratoire
FR2420545A1 (fr) * 1978-03-20 1979-10-19 Anvar Nouveaux esters de l'acide n-acetyl-muramyl-aminoacyl-glutamique ou des derives de substitution de celui-ci a proprietes anti-infectieuses et/ou d'adjuvants immunologiques
EP0014159A1 (fr) * 1979-01-29 1980-08-06 Merck & Co. Inc. Dipeptidyl saccharides immunologiquement actifs et méthodes de préparation
EP0014984A1 (fr) * 1979-02-21 1980-09-03 Takeda Chemical Industries, Ltd. Dérivés peptidiques de la glucosamine, leur préparation et leur utilisation
EP0021367A1 (fr) * 1979-06-21 1981-01-07 Daiichi Seiyaku Co., Ltd. Dérivés de muramyldipeptides, procédé pour leur préparation et compositions pharmaceutiques les contenant
EP0025495A1 (fr) * 1979-07-25 1981-03-25 Ciba-Geigy Ag Muramyl peptides à activité lipophyle, procédés pour les préparer et leur utilisation
EP0027258A1 (fr) * 1979-10-12 1981-04-22 Ciba-Geigy Ag Phosphorylmuramyl peptides, procédé pour leur préparation et leur utilisation dans des médicaments
EP0056992A1 (fr) * 1981-01-23 1982-08-04 Ciba-Geigy Ag Dérivés phosphorylés, compositions pharmaceutiques contenant ces dérivés et leur application

Also Published As

Publication number Publication date
ATA909276A (de) 1981-06-15
PL110787B1 (en) 1980-07-31
DK154654B (da) 1988-12-05
DE2655500C2 (fr) 1988-12-22
CA1262400A (fr) 1989-10-17
AR224091A1 (es) 1981-10-30
NO144850B (no) 1981-08-17
DE2655500A1 (de) 1977-06-23
DK154654C (da) 1989-05-08
SU660589A3 (ru) 1979-04-30
CS205028B2 (en) 1981-04-30
AR220686A1 (es) 1980-11-28
FR2361902B1 (fr) 1980-11-07
PT65946A (en) 1977-01-01
IE44190L (en) 1977-06-10
SU1060118A3 (ru) 1983-12-07
ZA767333B (en) 1977-11-30
CS205025B2 (en) 1981-04-30
PL110794B1 (en) 1980-07-31
IL51076A (en) 1980-09-16
JPS5273820A (en) 1977-06-21
CS205026B2 (en) 1981-04-30
AT365607B (de) 1982-02-10
FI64164B (fi) 1983-06-30
DK552476A (da) 1977-06-11
NZ182837A (en) 1978-07-28
FI763541A7 (fr) 1977-06-11
CH614718A5 (en) 1979-12-14
CS205027B2 (en) 1981-04-30
SE7613851L (sv) 1977-06-11
GB1570625A (en) 1980-07-02
GR61647B (en) 1978-12-05
BE849214A (fr) 1977-06-09
AU508764B2 (en) 1980-04-03
JPS638118B2 (fr) 1988-02-19
IL51076A0 (en) 1977-02-28
IE44190B1 (en) 1981-09-09
PL110353B1 (en) 1980-07-31
DD129781A5 (de) 1978-02-08
MY8400123A (en) 1984-12-31
ES454118A1 (es) 1978-03-01
PL112672B1 (en) 1980-10-31
NL7613666A (nl) 1977-06-14
ES465514A1 (es) 1978-09-16
HK32883A (en) 1983-09-02
PT65946B (en) 1978-06-14
SG11083G (en) 1983-09-16
SU747430A3 (ru) 1980-07-23
CH613709A5 (en) 1979-10-15
NO764191L (fr) 1977-06-13
FI64164C (fi) 1983-10-10
HU177970B (en) 1982-02-28
SE445923B (sv) 1986-07-28
AU2042276A (en) 1978-06-15
NO144850C (no) 1981-11-25
PL194291A1 (pl) 1978-10-23

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Legal Events

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ST Notification of lapse