CS204035B2 - Method of producing dihydrochloride monohydrate of racemic 3-/2-/3-tertiary butylamino-2-hydroxypropoxy/-phenyl/-6-hydrazinopyridazine - Google Patents

Method of producing dihydrochloride monohydrate of racemic 3-/2-/3-tertiary butylamino-2-hydroxypropoxy/-phenyl/-6-hydrazinopyridazine Download PDF

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Publication number
CS204035B2
CS204035B2 CS785723A CS572378A CS204035B2 CS 204035 B2 CS204035 B2 CS 204035B2 CS 785723 A CS785723 A CS 785723A CS 572378 A CS572378 A CS 572378A CS 204035 B2 CS204035 B2 CS 204035B2
Authority
CS
Czechoslovakia
Prior art keywords
dihydrochloride monohydrate
water
racemic
phenyl
hydrazinopyridazine
Prior art date
Application number
CS785723A
Other languages
Czech (cs)
English (en)
Inventor
Brian E Burpitt
Michael J Graham
Anthony M Roe
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of CS204035B2 publication Critical patent/CS204035B2/cs

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/20Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CS785723A 1978-08-04 1978-09-04 Method of producing dihydrochloride monohydrate of racemic 3-/2-/3-tertiary butylamino-2-hydroxypropoxy/-phenyl/-6-hydrazinopyridazine CS204035B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7832312 1978-08-04

Publications (1)

Publication Number Publication Date
CS204035B2 true CS204035B2 (en) 1981-03-31

Family

ID=10498866

Family Applications (1)

Application Number Title Priority Date Filing Date
CS785723A CS204035B2 (en) 1978-08-04 1978-09-04 Method of producing dihydrochloride monohydrate of racemic 3-/2-/3-tertiary butylamino-2-hydroxypropoxy/-phenyl/-6-hydrazinopyridazine

Country Status (29)

Country Link
EP (1) EP0007930B1 (bg)
JP (1) JPS6040424B2 (bg)
AR (1) AR223327A1 (bg)
AT (1) AT361001B (bg)
BG (1) BG34335A3 (bg)
CA (1) CA1098522A (bg)
CS (1) CS204035B2 (bg)
DD (1) DD138656A5 (bg)
DE (1) DE2862214D1 (bg)
DK (1) DK147761C (bg)
EG (1) EG13469A (bg)
ES (1) ES473056A1 (bg)
FI (1) FI64585C (bg)
GR (1) GR64897B (bg)
HU (1) HU181959B (bg)
IE (1) IE47555B1 (bg)
IL (1) IL55455A (bg)
IN (1) IN148775B (bg)
IT (1) IT1110169B (bg)
MT (1) MTP851B (bg)
MX (1) MX5425E (bg)
NO (1) NO783005L (bg)
NZ (1) NZ188281A (bg)
OA (1) OA06046A (bg)
PL (1) PL119444B1 (bg)
SU (1) SU897110A3 (bg)
YU (1) YU209078A (bg)
ZA (1) ZA785008B (bg)
ZM (1) ZM8078A1 (bg)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE42214B1 (en) * 1974-06-18 1980-07-02 Smith Kline French Lab Hydrazinopyredazines

Also Published As

Publication number Publication date
NO783005L (no) 1980-02-05
ES473056A1 (es) 1979-05-01
DK147761B (da) 1984-12-03
FI64585B (fi) 1983-08-31
SU897110A3 (ru) 1982-01-07
MTP851B (en) 1980-06-30
YU209078A (en) 1982-10-31
IN148775B (bg) 1981-06-13
AT361001B (de) 1981-02-10
ATA638378A (de) 1980-07-15
DK389378A (da) 1980-02-05
IE47555B1 (en) 1984-04-18
EP0007930B1 (en) 1983-03-30
IL55455A (en) 1981-11-30
FI64585C (fi) 1983-12-12
IT1110169B (it) 1985-12-23
IT7827234A0 (it) 1978-08-31
HU181959B (en) 1983-11-28
OA06046A (fr) 1981-06-30
CA1098522A (en) 1981-03-31
JPS6040424B2 (ja) 1985-09-11
NZ188281A (en) 1980-11-14
DE2862214D1 (en) 1983-05-05
ZA785008B (en) 1979-08-29
ZM8078A1 (en) 1979-07-19
AR223327A1 (es) 1981-08-14
PL209407A1 (bg) 1980-05-19
DK147761C (da) 1985-05-20
EG13469A (en) 1982-06-30
EP0007930A1 (en) 1980-02-20
MX5425E (es) 1983-08-03
BG34335A3 (bg) 1983-08-15
DD138656A5 (de) 1979-11-14
IE781702L (en) 1980-02-04
PL119444B1 (en) 1981-12-31
JPS5522651A (en) 1980-02-18
FI782705A (fi) 1980-02-05
GR64897B (en) 1980-06-07

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