CS199686B2 - Process for preparing new substituted n-cycloalkylmethyl-2-phenylamino-2-imidazolines - Google Patents

Process for preparing new substituted n-cycloalkylmethyl-2-phenylamino-2-imidazolines Download PDF

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Publication number
CS199686B2
CS199686B2 CS775341A CS534177A CS199686B2 CS 199686 B2 CS199686 B2 CS 199686B2 CS 775341 A CS775341 A CS 775341A CS 534177 A CS534177 A CS 534177A CS 199686 B2 CS199686 B2 CS 199686B2
Authority
CS
Czechoslovakia
Prior art keywords
acid
compounds
formula
reaction
cycloalkylmethyl
Prior art date
Application number
CS775341A
Other languages
Czech (cs)
English (en)
Inventor
Helmut Staehle
Herbert Koeppe
Werner Kummer
Klaus Stockhaus
Wolfgang Hoefke
Franz-Josef Kuhn
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Priority to CS79903A priority Critical patent/CS199687B2/cs
Publication of CS199686B2 publication Critical patent/CS199686B2/cs

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CS775341A 1976-08-14 1977-08-12 Process for preparing new substituted n-cycloalkylmethyl-2-phenylamino-2-imidazolines CS199686B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS79903A CS199687B2 (cs) 1976-08-14 1979-02-09 Způsob výroby nových substituovaných N-cykloalkylmethyl- -2-fenylamino-2-imidazolinů

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762636732 DE2636732A1 (de) 1976-08-14 1976-08-14 Neue substituierte 2-phenylamino- imidazoline- (2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben

Publications (1)

Publication Number Publication Date
CS199686B2 true CS199686B2 (en) 1980-07-31

Family

ID=5985507

Family Applications (1)

Application Number Title Priority Date Filing Date
CS775341A CS199686B2 (en) 1976-08-14 1977-08-12 Process for preparing new substituted n-cycloalkylmethyl-2-phenylamino-2-imidazolines

Country Status (31)

Country Link
US (1) US4100292A (pl)
JP (1) JPS6026112B2 (pl)
AT (1) AT357152B (pl)
AU (1) AU507063B2 (pl)
BE (1) BE857778A (pl)
CA (1) CA1085861A (pl)
CH (2) CH630906A5 (pl)
CS (1) CS199686B2 (pl)
DD (1) DD132964A5 (pl)
DE (1) DE2636732A1 (pl)
DK (1) DK152042C (pl)
ES (2) ES461598A1 (pl)
FI (1) FI64147C (pl)
FR (1) FR2361371A1 (pl)
GB (1) GB1548518A (pl)
GR (1) GR63351B (pl)
HU (1) HU175055B (pl)
IE (1) IE45556B1 (pl)
IL (1) IL52717A (pl)
LU (1) LU77961A1 (pl)
MX (1) MX4649E (pl)
NL (1) NL7708910A (pl)
NO (1) NO145275C (pl)
NZ (1) NZ184912A (pl)
PH (1) PH13735A (pl)
PL (2) PL102537B1 (pl)
PT (1) PT66918B (pl)
RO (1) RO76806A (pl)
SE (1) SE441184B (pl)
SU (2) SU660592A3 (pl)
ZA (1) ZA774875B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2830279A1 (de) * 1978-07-10 1980-01-31 Boehringer Sohn Ingelheim 2-eckige klammer auf n-(2'-chlor-4'- methyl-thienyl-3')-n-(cyclopropylmethyl)- amino eckige klammer zu-imidazolin-(2), dessen saeureadditionssalze, dieses enthaltende arzneimittel und verfahren zu seiner herstellung
DE2831234A1 (de) * 1978-07-15 1980-01-31 Boehringer Sohn Ingelheim Neue substituierte 2-phenylamino-imidazoline-(2) deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
DE2855306A1 (de) * 1978-12-21 1980-07-10 Boehringer Sohn Ingelheim Mittel zur senkung der herzfrequenz
US4255439A (en) * 1979-07-13 1981-03-10 Irving Cooper Means and method for aiding individuals to stop smoking
DE2947563A1 (de) * 1979-11-26 1981-06-04 C.H. Boehringer Sohn, 6507 Ingelheim Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
DE2949287A1 (de) * 1979-12-07 1981-06-11 C.H. Boehringer Sohn, 6507 Ingelheim Neue substituierte 2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
DE3200258A1 (de) * 1982-01-07 1983-07-21 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München Substituierte 1-benzoyl-2-phenylimino-imidazolidine, deren saeureadditionssalze, verfahren zu deren herstellung und diese enthaltende arzneimittel
GB8304593D0 (en) * 1983-02-18 1983-03-23 Beecham Group Plc Amidines
JPS6421906U (pl) * 1987-07-31 1989-02-03
JPH0543404U (ja) * 1991-11-07 1993-06-11 株式会社小糸製作所 車両用灯具
CN117534617B (zh) * 2023-12-21 2024-04-05 四川大学华西医院 一类2-氨基咪唑啉类化合物、其用途和含该化合物的药物组合物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3202660A (en) * 1961-10-09 1965-08-24 Boehringer Sohn Ingelheim Process for the preparation of 3-arylamino-1, 3-diazacycloalkenes
BE759048A (fr) * 1969-11-17 1971-05-17 Boehringer Sohn Ingelheim Nouvelles n-aminoalcoyl-arylamino-imidazolines-(2) substituees et procedes pour les fabriquer
BE759126A (fr) * 1969-11-19 1971-05-18 Boehringer Sohn Ingelheim Nouvelles n-cycloalcoyl-arylamino-imidazolines-(2) substituees et procedes pour les fabriquer
BE759125A (fr) * 1969-11-19 1971-05-18 Boehringer Sohn Ingelheim Nouvelles n-allyl-2-arylamino-imidazolines-(2) substituees et procedes pour les fabriquer
DE2016290A1 (de) * 1970-04-06 1971-11-04 C H Boehrmger Sohn, 6507 Ingel heim Substituierte N Hydroxylakyl 2 arylamine) imidazoline (2) und Verfahren zu deren Herstellung
DD95843A5 (pl) * 1971-01-21 1973-02-20
US3850926A (en) * 1971-01-21 1974-11-26 Boehringer Sohn Ingelheim 2-(n-substituted-phenylamino)-imidazolines-(2)
DE2259160A1 (de) * 1972-12-02 1974-06-06 Boehringer Sohn Ingelheim Neue substituierte 2-phenylaminoimidazoline, deren saeureadditionssalze und verfahren zur herstellung derselben sowie ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
CA1085861A (en) 1980-09-16
PT66918A (de) 1977-08-31
IL52717A0 (en) 1977-10-31
HU175055B (hu) 1980-05-28
FI772221A (pl) 1978-02-15
JPS6026112B2 (ja) 1985-06-21
ATA568977A (de) 1979-11-15
GB1548518A (en) 1979-07-18
RO76806A (ro) 1981-05-30
DK359577A (da) 1978-02-15
GR63351B (en) 1979-10-20
AU2788977A (en) 1979-03-08
AT357152B (de) 1980-06-25
PL102537B1 (pl) 1979-04-30
JPS5325567A (en) 1978-03-09
PL200251A1 (pl) 1978-05-22
PH13735A (en) 1980-09-10
SE7709158L (sv) 1978-02-15
FI64147C (fi) 1983-10-10
IE45556B1 (en) 1982-09-22
DD132964A5 (de) 1978-11-22
NO145275B (no) 1981-11-09
NZ184912A (en) 1979-10-25
IL52717A (en) 1980-12-31
SU660592A3 (ru) 1979-04-30
ES465225A1 (es) 1978-09-16
LU77961A1 (pl) 1978-09-14
AU507063B2 (en) 1980-01-31
SE441184B (sv) 1985-09-16
IE45556L (en) 1978-02-14
MX4649E (es) 1982-07-15
NO772825L (no) 1978-02-15
US4100292A (en) 1978-07-11
DK152042B (da) 1988-01-25
FR2361371A1 (fr) 1978-03-10
ZA774875B (en) 1979-04-25
SU677655A3 (ru) 1979-07-30
DK152042C (da) 1988-06-20
FI64147B (fi) 1983-06-30
NL7708910A (nl) 1978-02-16
FR2361371B1 (pl) 1980-09-12
BE857778A (fr) 1978-02-13
CH631970A5 (de) 1982-09-15
DE2636732A1 (de) 1978-02-16
PT66918B (de) 1979-07-13
CH630906A5 (de) 1982-07-15
NO145275C (no) 1982-02-17
ES461598A1 (es) 1978-06-01
PL103477B1 (pl) 1979-06-30

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