CS196376B2 - Method for the stereoselective production of optical isomers of hexahydrodibenzopyranone derivatives - Google Patents

Method for the stereoselective production of optical isomers of hexahydrodibenzopyranone derivatives Download PDF

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Publication number
CS196376B2
CS196376B2 CS774518A CS451877A CS196376B2 CS 196376 B2 CS196376 B2 CS 196376B2 CS 774518 A CS774518 A CS 774518A CS 451877 A CS451877 A CS 451877A CS 196376 B2 CS196376 B2 CS 196376B2
Authority
CS
Czechoslovakia
Prior art keywords
acid
dimethyl
reaction
trans
cis
Prior art date
Application number
CS774518A
Other languages
Czech (cs)
English (en)
Inventor
Robert A Archer
William A Day
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Priority to CS782081A priority Critical patent/CS196377B2/cs
Publication of CS196376B2 publication Critical patent/CS196376B2/cs

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Saccharide Compounds (AREA)
CS774518A 1976-11-10 1977-07-06 Method for the stereoselective production of optical isomers of hexahydrodibenzopyranone derivatives CS196376B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CS782081A CS196377B2 (cs) 1976-11-10 1978-03-31 Způsob výroby opticky aktivních derivátů norpinenu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/740,502 US4102902A (en) 1976-11-10 1976-11-10 Stereoselective preparation of hexahydro dibenzopyranones and intermediates therefor

Publications (1)

Publication Number Publication Date
CS196376B2 true CS196376B2 (en) 1980-03-31

Family

ID=24976773

Family Applications (1)

Application Number Title Priority Date Filing Date
CS774518A CS196376B2 (en) 1976-11-10 1977-07-06 Method for the stereoselective production of optical isomers of hexahydrodibenzopyranone derivatives

Country Status (30)

Country Link
US (1) US4102902A (de)
JP (2) JPS5925792B2 (de)
AT (1) AT356103B (de)
AU (1) AU509355B2 (de)
BE (1) BE856413A (de)
BG (2) BG28411A4 (de)
CA (1) CA1101875A (de)
CH (2) CH632506A5 (de)
CS (1) CS196376B2 (de)
DD (2) DD140455A5 (de)
DE (3) DE2760005C2 (de)
DK (1) DK301477A (de)
ES (3) ES460389A1 (de)
FR (1) FR2370742A1 (de)
GB (2) GB1584181A (de)
GR (1) GR66417B (de)
HU (2) HU177308B (de)
IE (1) IE45247B1 (de)
IL (3) IL52427A (de)
MX (1) MX5172E (de)
NL (1) NL7707467A (de)
NZ (1) NZ184526A (de)
PH (3) PH13827A (de)
PL (2) PL104356B1 (de)
PT (1) PT66746B (de)
RO (1) RO78780A (de)
SE (3) SE428020B (de)
SU (2) SU786898A3 (de)
YU (1) YU163677A (de)
ZA (1) ZA773960B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL55274A (en) * 1978-08-02 1982-08-31 Yissum Res Dev Co 4-(2,6-dihydroxy-4-(dimethylheptyl)phenyl)substituted 2-pinen-10-ol and pinane derivatives,their preparation and pharmaceutical compositions comprising them
US4939169A (en) * 1985-09-20 1990-07-03 The Upjohn Company 1,4-naphthalenediol and 1,4-hydroquinone derivatives
EP0246245A1 (de) * 1985-09-20 1987-11-25 The Upjohn Company 1,4-naphthalindiol- und 1,4-hydrochinon-abkömmlinge
IL80411A (en) * 1986-10-24 1991-08-16 Raphael Mechoulam Preparation of dibenzopyranol derivatives and pharmaceutical compositions containing them
JPH0315035A (ja) * 1989-03-03 1991-01-23 Konica Corp カメラ
JP2577671B2 (ja) * 1990-06-11 1997-02-05 高砂熱学工業株式会社 気化式精密加湿装置
US20010009965A1 (en) * 1998-05-04 2001-07-26 Alexandros Makriyannis Novel analgesic and immunomodulatory cannabinoids
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US6943266B1 (en) * 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US7119108B1 (en) 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
WO2001028497A2 (en) * 1999-10-18 2001-04-26 University Of Connecticut Novel bicyclic cannabinoid agonists for the cannabinoid receptor
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US6900236B1 (en) 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
JP2003511469A (ja) 1999-10-18 2003-03-25 ユニバーシティ オブ コネチカット 抹消カンナビノイド受容体（ｃｂ２）選択的配位子
EP1361876A4 (de) * 2001-01-26 2004-03-31 Univ Connecticut Neue cannabimimetische liganden
ATE478670T1 (de) 2001-01-29 2010-09-15 Univ Connecticut Rezeptor-selektive cannabimimetische aminoalkylindole
CA2452881C (en) * 2001-07-13 2012-03-06 University Of Connecticut Novel bicyclic and tricyclic cannabinoids
WO2003035005A2 (en) * 2001-10-26 2003-05-01 University Of Connecticut Heteroindanes: a new class of potent cannabimimetic ligands
CA2483072A1 (en) * 2002-04-25 2003-11-06 Virginia Commonwealth University Cannabinoids
EP1545502A4 (de) 2002-08-23 2008-12-24 Univ Connecticut Keto-cannabinoide mit therapeutischen indikationen
JP2009510078A (ja) 2005-09-29 2009-03-12 エーエムアール テクノロジー インコーポレイテッド Δ−９−テトラヒドロカンナビノールの生成法
US9763894B2 (en) * 2006-12-05 2017-09-19 Virginia Commonwealth University Inflammation therapy
PL222532B1 (pl) 2012-04-05 2016-08-31 Akademia Morska W Szczecinie Sposób i układ do diagnozowania układu wtryskowego silników o zapłonie samoczynnym, zwłaszcza silników okrętowych
US12029718B2 (en) 2021-11-09 2024-07-09 Cct Sciences, Llc Process for production of essentially pure delta-9-tetrahydrocannabinol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3856820A (en) * 1973-07-18 1974-12-24 Smithkline Corp 2-AMINOMETHYL DIBENZO (b,d) PYRANS
US3856821A (en) * 1973-07-18 1974-12-24 Smithkline Corp ALKOXY DIBENZO (b,d) PYRANS
US3856822A (en) * 1973-07-18 1974-12-24 Smithkline Corp 3-alkenyl dibenzo (b,d)pyrans
US3928598A (en) * 1973-11-05 1975-12-23 Lilly Co Eli Hexahydro-dibenzo{8 b,d{9 pyran-9-ones as an anti-anxiety drug

Also Published As

Publication number Publication date
DK301477A (da) 1978-05-11
PL199362A1 (pl) 1978-05-22
JPS5865244A (ja) 1983-04-18
BG28061A3 (en) 1980-02-25
SE428020B (sv) 1983-05-30
SE434510B (sv) 1984-07-30
IE45247L (en) 1978-05-10
ZA773960B (en) 1979-02-28
PT66746B (en) 1978-11-27
GR66417B (de) 1981-03-20
RO78780A (ro) 1982-04-12
DE2729859A1 (de) 1978-05-11
YU163677A (en) 1982-10-31
CH632506A5 (de) 1982-10-15
PL104432B1 (pl) 1979-08-31
IL52427A0 (en) 1977-08-31
PH13827A (en) 1980-10-07
GB1584181A (en) 1981-02-11
BE856413A (fr) 1978-01-04
SE7707633L (sv) 1978-05-11
DD140455A5 (de) 1980-03-05
US4102902A (en) 1978-07-25
IE45247B1 (en) 1982-07-14
HU183286B (en) 1984-04-28
CH632481A5 (de) 1982-10-15
DE2729859C2 (de) 1984-08-23
HU177308B (en) 1981-09-28
ES460387A1 (es) 1978-04-01
ATA483677A (de) 1979-09-15
SE8005314L (sv) 1980-07-22
IL52427A (en) 1981-10-30
MX5172E (es) 1983-04-18
NZ184526A (en) 1979-03-16
PT66746A (en) 1977-07-01
ES460389A1 (es) 1978-04-16
AT356103B (de) 1980-04-10
JPS5359670A (en) 1978-05-29
DE2760005C2 (de) 1984-04-26
PH13890A (en) 1980-10-27
PH14708A (en) 1981-11-13
SU1128829A3 (ru) 1984-12-07
DD134350A5 (de) 1979-02-21
IL60589A0 (en) 1980-09-16
JPS5925792B2 (ja) 1984-06-21
GB1584182A (en) 1981-02-11
FR2370742A1 (fr) 1978-06-09
CA1101875A (en) 1981-05-26
AU2668477A (en) 1979-01-04
DE2760006C2 (de) 1985-07-04
NL7707467A (nl) 1978-05-12
SU786898A3 (ru) 1980-12-07
FR2370742B1 (de) 1980-12-26
JPS5912654B2 (ja) 1984-03-24
ES460388A1 (es) 1978-04-01
SE8005316L (sv) 1980-07-22
BG28411A4 (en) 1980-04-15
AU509355B2 (en) 1980-05-08
IL60590A0 (en) 1980-09-16
PL104356B1 (pl) 1979-08-31

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